Page last updated: 2024-10-25

chlorpyrifos and Arteriosclerosis

chlorpyrifos has been researched along with Arteriosclerosis in 2 studies

Chlorpyrifos: An organothiophosphate cholinesterase inhibitor that is used as an insecticide and as an acaricide.
chlorpyrifos : An organic thiophosphate that is O,O-diethyl hydrogen phosphorothioate in which the hydrogen of the hydroxy group has been replaced by a 3,5,6-trichloropyridin-2-yl group.

Arteriosclerosis: Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.

Research Excerpts

ExcerptRelevanceReference
" Compared with their wild-type littermates, PON1-deficient mice were extremely sensitive to the toxic effects of chlorpyrifos oxon, the activated form of chlorpyrifos, and were more sensitive to chlorpyrifos itself."1.30Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis. ( Castellani, LW; Costa, LG; Fogelman, AM; Furlong, CE; Gu, L; Hama, S; Li, WF; Lusis, AJ; Navab, M; Shih, DM; Xia, YR, 1998)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shih, DM1
Gu, L1
Xia, YR1
Navab, M1
Li, WF1
Hama, S1
Castellani, LW1
Furlong, CE1
Costa, LG1
Fogelman, AM1
Lusis, AJ1
Soulen, RL1
Freeman, E1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Serum Oxidative Status as a Potential Predictor of Coronary Artery Disease.[NCT03646019]200 participants (Anticipated)Observational2018-09-30Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for chlorpyrifos and Arteriosclerosis

ArticleYear
Radiologic evaluation of myocardial infarction.
    Radiologic clinics of North America, 1971, Volume: 9, Issue:3

    Topics: Acute Disease; Adult; Angiography; Arteriosclerosis; Chronic Disease; Cineangiography; Cineradiograp

1971

Other Studies

1 other study available for chlorpyrifos and Arteriosclerosis

ArticleYear
Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis.
    Nature, 1998, Jul-16, Volume: 394, Issue:6690

    Topics: Animals; Aorta; Arteriosclerosis; Aryldialkylphosphatase; Cells, Cultured; Chlorpyrifos; Cholinester

1998