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chlorpyrifos and Aging

chlorpyrifos has been researched along with Aging in 36 studies

Chlorpyrifos: An organothiophosphate cholinesterase inhibitor that is used as an insecticide and as an acaricide.
chlorpyrifos : An organic thiophosphate that is O,O-diethyl hydrogen phosphorothioate in which the hydrogen of the hydroxy group has been replaced by a 3,5,6-trichloropyridin-2-yl group.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
" In our previous study we have reported that co-exposure to chlorpyrifos and cold stress in aging rats markedly influence the toxic outcome as a result of oxidative stress."7.78Oxidative macromolecular alterations in the rat central nervous system in response to experimentally co-induced chlorpyrifos and cold stress: a comparative assessment in aging rats. ( Basha, PM; Poojary, A, 2012)
"Chlorpyrifos is a pesticide frequently detected in food and has been reported to disturb endocrine and gut health, which was regulated by gut microbiota and enteroendocrine cells."5.51Age- and diet-specific effects of chronic exposure to chlorpyrifos on hormones, inflammation and gut microbiota in rats. ( Fang, B; Li, JW; Pang, GF; Ren, FZ; Zhang, M, 2019)
"0mg/kg, but at a lower dosage (0."5.46Decreased anxiety in juvenile rats following exposure to low levels of chlorpyrifos during development. ( Armstrong, NH; Buchanan, AT; Carr, RL; Eells, JB; Mohammed, AN; Nail, CA; Ross, MK, 2017)
" We compared nicotinic autoreceptor function (NAF) during maturation and aging and evaluated its potential modulation by the common OP insecticide, chlorpyrifos (CPF)."3.72Nicotinic autoreceptor function in rat brain during maturation and aging: possible differential sensitivity to organophosphorus anticholinesterases. ( Harp, P; Pope, CN; Wu, YJ; Yan, XR, 2003)
"Chlorpyrifos is a pesticide frequently detected in food and has been reported to disturb endocrine and gut health, which was regulated by gut microbiota and enteroendocrine cells."1.51Age- and diet-specific effects of chronic exposure to chlorpyrifos on hormones, inflammation and gut microbiota in rats. ( Fang, B; Li, JW; Pang, GF; Ren, FZ; Zhang, M, 2019)
"0mg/kg, but at a lower dosage (0."1.46Decreased anxiety in juvenile rats following exposure to low levels of chlorpyrifos during development. ( Armstrong, NH; Buchanan, AT; Carr, RL; Eells, JB; Mohammed, AN; Nail, CA; Ross, MK, 2017)
" Oral CPFO resulted in substantial RBC ChEI, but no brain ChEI, indicating no CPFO systemic bioavailability to peripheral tissues."1.38Cholinesterase inhibition and toxicokinetics in immature and adult rats after acute or repeated exposures to chlorpyrifos or chlorpyrifos-oxon. ( Andrus, AK; Bartels, MJ; Beck, MJ; Bell, MP; Brzak, KA; Juberg, DR; Marty, MS; Passage, JK; Perala, AW, 2012)
"Chlorpyrifos (CPF) is a common organophosphorus (OP) pesticide."1.31Comparative cholinergic neurotoxicity of oral chlorpyrifos exposures in preweanling and adult rats. ( Olivier, K; Pope, CN; Won, YK; Zheng, Q, 2000)
"Chlorpyrifos (CPF) is an organophosphorus insecticide that elicits toxicity through inhibition of acetylcholinesterase (AChE)."1.31Age-related effects of chlorpyrifos on acetylcholine release in rat brain. ( Liu, J; Olivier, K; Pope, CN; Won, YK; Zheng, Q, 2001)

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19904 (11.11)18.7374
1990's7 (19.44)18.2507
2000's12 (33.33)29.6817
2010's10 (27.78)24.3611
2020's3 (8.33)2.80

Authors

AuthorsStudies
Zhong, Y1
Ding, Q1
Huang, Z1
Xiao, X1
Han, X1
Su, Y1
Wang, D1
You, J1
Li, JW1
Fang, B1
Pang, GF1
Zhang, M1
Ren, FZ1
Perez-Fernandez, C1
Morales-Navas, M1
Guardia-Escote, L1
Colomina, MT2
Giménez, E1
Sánchez Santed, F1
Carr, RL3
Adams, AL1
Kepler, DR1
Ward, AB1
Ross, MK2
Basha, PM4
Poojary, A4
Armstrong, NH1
Buchanan, AT1
Eells, JB1
Mohammed, AN1
Nail, CA1
López-Granero, C1
Ruiz-Muñoz, AM1
Nieto-Escámez, FA1
Aschner, M1
Sánchez-Santed, F1
Billauer-Haimovitch, H1
Slotkin, TA3
Dotan, S1
Langford, R1
Pinkas, A1
Yanai, J1
Smith, JN1
Timchalk, C2
Bartels, MJ2
Poet, TS2
Marty, MS1
Andrus, AK1
Bell, MP1
Passage, JK1
Perala, AW1
Brzak, KA1
Beck, MJ1
Juberg, DR1
Wu, YJ1
Harp, P1
Yan, XR1
Pope, CN8
Karanth, S2
Liu, J3
Yan, B1
Chandrasekara, LW1
Pathiratne, A1
Kousba, AA1
Padilla, S3
Chakraborti, TK3
Farrar, JD2
Chambers, JE1
Mortensen, SR2
Chanda, SM1
Hooper, MJ2
Brimijoin, S1
Dam, K1
Seidler, FJ2
Zheng, Q2
Olivier, K3
Won, YK2
Pope, C2
Howard, MD1
Tate, CA1
Cousins, MM1
Chapman, ML1
Arthun, D1
Long, GG1
Scheidt, AB1
Everson, RJ1
Oehme, FW1
Capuano, AW1
Shah, RC1
Blanche, P1
Wilson, RS1
Barnes, LL1
Bennett, DA1
Arvanitakis, Z1
Pfister, A1
Deltour, G1
Kaiser, R1
Vendrely, E1
Milroy, WC1
Michaelson, SM1
Cleary, SF1
Pasternack, BS1
Beebe, GW1

Reviews

1 review available for chlorpyrifos and Aging

ArticleYear
Microwave cataractogenesis: a critical review of the literature.
    Aerospace medicine, 1972, Volume: 43, Issue:1

    Topics: Adult; Aging; Animals; Body Temperature; Cataract; Diathermy; Dogs; Evaluation Studies as Topic; Fem

1972

Other Studies

35 other studies available for chlorpyrifos and Aging

ArticleYear
Influence of ultraviolet-aging and adsorbed pollutants on toxicological effects of polyvinyl chloride microplastics to zebrafish.
    Environmental pollution (Barking, Essex : 1987), 2023, Jan-01, Volume: 316, Issue:Pt 2

    Topics: Adsorption; Aging; Animals; Chlorpyrifos; Environmental Pollutants; Microplastics; Plastics; Polyvin

2023
Age- and diet-specific effects of chronic exposure to chlorpyrifos on hormones, inflammation and gut microbiota in rats.
    Pesticide biochemistry and physiology, 2019, Volume: 159

    Topics: Aging; Animals; Chlorpyrifos; Diet, High-Fat; Gastrointestinal Microbiome; Hypothalamo-Hypophyseal S

2019
Pesticides and aging: Preweaning exposure to Chlorpyrifos induces a general hypomotricity state in late-adult rats.
    Neurotoxicology, 2021, Volume: 86

    Topics: Age Factors; Aging; Animals; Animals, Newborn; Chlorpyrifos; Female; Insecticides; Male; Maze Learni

2021
Induction of endocannabinoid levels in juvenile rat brain following developmental chlorpyrifos exposure.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 135, Issue:1

    Topics: Aging; Amidohydrolases; Animals; Arachidonic Acids; Brain; Chlorpyrifos; Cholinesterase Inhibitors;

2013
Mitochondrial dysfunction in aging rat brain regions upon chlorpyrifos toxicity and cold stress: an interactive study.
    Cellular and molecular neurobiology, 2014, Volume: 34, Issue:5

    Topics: Aging; Animals; Animals, Newborn; Brain; Chlorpyrifos; Cold Temperature; Male; Mitochondria; Oxidati

2014
Decreased anxiety in juvenile rats following exposure to low levels of chlorpyrifos during development.
    Neurotoxicology, 2017, Volume: 59

    Topics: Aging; Analysis of Variance; Animals; Animals, Newborn; Anxiety; Arachidonic Acids; Chlorpyrifos; Ch

2017
Chronic dietary chlorpyrifos causes long-term spatial memory impairment and thigmotaxic behavior.
    Neurotoxicology, 2016, Volume: 53

    Topics: Aging; Animals; Anti-Anxiety Agents; Chlorpyrifos; Cholinesterase Inhibitors; Cues; Diazepam; Dizoci

2016
Reversal of chlorpyrifos neurobehavioral teratogenicity in mice by nicotine administration and neural stem cell transplantation.
    Behavioural brain research, 2009, Dec-28, Volume: 205, Issue:2

    Topics: Aging; Animals; Brain; Chlorpyrifos; Dose-Response Relationship, Drug; Female; Insecticides; Learnin

2009
Chlorpyrifos induced region specific vulnerability in rat CNS and modulation by age and cold stress: an interactive study.
    Neurochemical research, 2011, Volume: 36, Issue:2

    Topics: Aging; Animals; Catalase; Central Nervous System; Chlorpyrifos; Cold Temperature; Glutathione; Gluta

2011
In vitro age-dependent enzymatic metabolism of chlorpyrifos and chlorpyrifos-oxon in human hepatic microsomes and chlorpyrifos-oxon in plasma.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:8

    Topics: Adolescent; Adult; Aged; Aging; Biotransformation; Child; Child, Preschool; Chlorpyrifos; Female; Hu

2011
Oxidative macromolecular alterations in the rat central nervous system in response to experimentally co-induced chlorpyrifos and cold stress: a comparative assessment in aging rats.
    Neurochemical research, 2012, Volume: 37, Issue:2

    Topics: Aging; Animals; Central Nervous System; Chlorpyrifos; Cholinesterase Inhibitors; Cold Temperature; M

2012
Cholinesterase inhibition and toxicokinetics in immature and adult rats after acute or repeated exposures to chlorpyrifos or chlorpyrifos-oxon.
    Regulatory toxicology and pharmacology : RTP, 2012, Volume: 63, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Behavior, Animal; Brain; Chlorpyrifos; Cholinesterase Inhibitors;

2012
Cold stress interaction on organophosphate insecticide poisoning: age-related assessment in rat cerebral cortex.
    Indian journal of experimental biology, 2012, Volume: 50, Issue:2

    Topics: Acetylcholinesterase; Aging; Animals; Cerebral Cortex; Chlorpyrifos; Cold Temperature; Insecticides;

2012
Nicotinic autoreceptor function in rat brain during maturation and aging: possible differential sensitivity to organophosphorus anticholinesterases.
    Chemico-biological interactions, 2003, Jan-06, Volume: 142, Issue:3

    Topics: Acetylcholine; Aging; Animals; Animals, Newborn; Atropine; Brain; Chlorpyrifos; Cholinesterase Inhib

2003
Comparative carboxylesterase activities in infant and adult liver and their in vitro sensitivity to chlorpyrifos oxon.
    Regulatory toxicology and pharmacology : RTP, 2005, Volume: 42, Issue:1

    Topics: Adult; Aging; Carboxylesterase; Chlorpyrifos; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System

2005
Body size-related differences in the inhibition of brain acetylcholinesterase activity in juvenile Nile tilapia (Oreochromis niloticus) by chlorpyrifos and carbosulfan.
    Ecotoxicology and environmental safety, 2007, Volume: 67, Issue:1

    Topics: Acetylcholinesterase; Aging; Animals; Biomarkers; Body Size; Brain; Carbamates; Chlorpyrifos; Cholin

2007
Age-related brain cholinesterase inhibition kinetics following in vitro incubation with chlorpyrifos-oxon and diazinon-oxon.
    Toxicological sciences : an official journal of the Society of Toxicology, 2007, Volume: 95, Issue:1

    Topics: Acetylcholinesterase; Age Factors; Aging; Animals; Animals, Newborn; Brain; Chlorpyrifos; Cholineste

2007
Re: age-related brain cholinesterase inhibition kinetics following in vitro incubation with chlorpyrifos-oxon and diazinon-oxon.
    Toxicological sciences : an official journal of the Society of Toxicology, 2007, Volume: 98, Issue:2

    Topics: Acetylcholinesterase; Age Factors; Aging; Animals; Animals, Newborn; Brain; Chlorpyrifos; Cholineste

2007
Comparative neurochemical and neurobehavioral effects of repeated chlorpyrifos exposures in young and adult rats.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 46, Issue:1

    Topics: Aging; Animals; Behavior, Animal; Biomarkers; Body Weight; Brain; Brain Chemistry; Chlorpyrifos; Cho

1993
Kinetic analysis of the in vitro inhibition, aging, and reactivation of brain acetylcholinesterase from rat and channel catfish by paraoxon and chlorpyrifos-oxon.
    Toxicology and applied pharmacology, 1996, Volume: 139, Issue:2

    Topics: Acetylcholinesterase; Aging; Animals; Brain; Brain Chemistry; Chlorpyrifos; Cholinesterase Inhibitor

1996
Maturational differences in chlorpyrifos-oxonase activity may contribute to age-related sensitivity to chlorpyrifos.
    Journal of biochemical toxicology, 1996, Volume: 11, Issue:6

    Topics: Acetylcholinesterase; Aging; Animals; Animals, Newborn; Brain; Chlorpyrifos; Esterases; Female; Inse

1996
Comparison of the in vitro sensitivity of rat acetylcholinesterase to chlorpyrifos-oxon: what do tissue IC50 values represent?
    Toxicology and applied pharmacology, 1998, Volume: 148, Issue:1

    Topics: Acetylcholinesterase; Aging; Animals; Brain; Chlorpyrifos; Cholinesterase Inhibitors; Female; In Vit

1998
Chlorpyrifos releases norepinephrine from adult and neonatal rat brain synaptosomes.
    Brain research. Developmental brain research, 1999, Dec-10, Volume: 118, Issue:1-2

    Topics: Aging; Animals; Animals, Newborn; Brain; Chlorpyrifos; Cholinergic Antagonists; Female; Insecticides

1999
Comparative cholinergic neurotoxicity of oral chlorpyrifos exposures in preweanling and adult rats.
    Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 55, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Animals, Suckling; Autonomic Nervous System Diseases; Body Weight;

2000
Carboxylesterase and A-esterase activities during maturation and aging: relationship to the toxicity of chlorpyrifos and parathion in rats.
    Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 58, Issue:2

    Topics: Age Factors; Aging; Animals; Carboxylic Ester Hydrolases; Chlorpyrifos; Esterases; Female; Insectici

2000
Age-related effects of chlorpyrifos on acetylcholine release in rat brain.
    Neurotoxicology, 2001, Volume: 22, Issue:1

    Topics: Acetylcholine; Aging; Animals; Animals, Newborn; Autoreceptors; Brain Chemistry; Cerebral Cortex; Ch

2001
In vitro effects of chlorpyrifos, parathion, methyl parathion and their oxons on cardiac muscarinic receptor binding in neonatal and adult rats.
    Toxicology, 2002, Jan-15, Volume: 170, Issue:1-2

    Topics: Aging; Animals; Animals, Newborn; Binding, Competitive; Chlorpyrifos; Cholinesterase Inhibitors; Fem

2002
Inhibition of forskolin-stimulated cAMP formation in vitro by paraoxon and chlorpyrifos oxon in cortical slices from neonatal, juvenile, and adult rats.
    Journal of biochemical and molecular toxicology, 2001, Volume: 15, Issue:5

    Topics: Aging; Animals; Animals, Newborn; Chlorpyrifos; Colforsin; Cyclic AMP; Female; In Vitro Techniques;

2001
Functional alterations in CNS catecholamine systems in adolescence and adulthood after neonatal chlorpyrifos exposure.
    Brain research. Developmental brain research, 2002, Feb-28, Volume: 133, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Brain; Catecholamines; Chlorpyrifos; Dopamine; Dose-Response Relat

2002
Dose-related inhibition of brain and plasma cholinesterase in neonatal and adult rats following sublethal organophosphate exposures.
    Toxicology, 1992, Volume: 73, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Brain; Chlorpyrifos; Cholinesterase Inhibitors; Cholinesterases; D

1992
Comparison of in vivo cholinesterase inhibition in neonatal and adult rats by three organophosphorothioate insecticides.
    Toxicology, 1991, Volume: 68, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Brain; Brain Chemistry; Chlorpyrifos; Cholinesterase Inhibitors; C

1991
Age related susceptibility of newborn pigs to the cutaneous application of chlorpyrifos.
    Veterinary and human toxicology, 1986, Volume: 28, Issue:4

    Topics: Administration, Topical; Aging; Animals; Animals, Newborn; Chlorpyrifos; Cholinesterases; Drug Resis

1986
Derivation and validation of the Rapid Assessment of Dementia Risk (RADaR) for older adults.
    PloS one, 2022, Volume: 17, Issue:3

    Topics: Aged; Aged, 80 and over; Aging; Child, Preschool; Cohort Studies; Dementia; Humans; Radar; Risk Asse

2022
[Radioautographic procedures and their value in research (3d part)].
    Revue des corps de sante des armees terre, mer, air, 1968, Volume: 9, Issue:2

    Topics: Aging; Animals; Autoradiography; Hypoxia; Methods; Mice; Mononuclear Phagocyte System; Radar; Radiat

1968
Cataract incidence in radar workers.
    Archives of environmental health, 1965, Volume: 11, Issue:2

    Topics: Adult; Aging; Cataract; Humans; Middle Aged; Military Medicine; Radar; Radiation Injuries; United St

1965