Page last updated: 2024-10-25

chlorpyrifos and Acute Liver Injury, Drug-Induced

chlorpyrifos has been researched along with Acute Liver Injury, Drug-Induced in 15 studies

Chlorpyrifos: An organothiophosphate cholinesterase inhibitor that is used as an insecticide and as an acaricide.
chlorpyrifos : An organic thiophosphate that is O,O-diethyl hydrogen phosphorothioate in which the hydrogen of the hydroxy group has been replaced by a 3,5,6-trichloropyridin-2-yl group.

Research Excerpts

ExcerptRelevanceReference
" This study evaluated the potential of RBR extract to prevent chlorpyrifos (CPF)-induced liver injury, with an emphasis on oxidative stress, inflammation and apoptosis."3.91Ameliorative Effect of ( Al-Kubaisi, N; Al-Otibi, FO; Albasher, G; Almeer, R; Mahmoud, AM, 2019)
" The role of essential trace elements as the promising and efficient preventive prophylactic agents without any toxicity and side effects in attenuating the adverse effects caused by pesticides, have been reported by various scientists, the world over."2.50Current view of zinc as a hepatoprotective agent in conditions of chlorpyrifos induced toxicity. ( Dhawan, DK; Malhotra, A, 2014)
" CPF can cause many toxic effects on human production and life."1.72Ros-mediated mitochondrial oxidative stress is involved in the ameliorating effect of ginsenoside GSLS on chlorpyrifos-induced hepatotoxicity in mice. ( Chen, W; Du, R; He, Z; Liu, J; Liu, S; Pei, H; Wu, H; Zeng, J, 2022)
"Chlorpyrifos (CPF) is a organophosphate insecticide widely used in agriculture with attendant adverse health outcomes."1.56Protective effects of molecular hydrogen on hepatotoxicity induced by sub-chronic exposure to chlorpyrifos in rats. ( Kong, XM; Li, XY; Li, ZY; Liu, MY; Ma, XM; Song, JM; Xie, F; Xun, ZM; Zhao, PX, 2020)
" (no observed adverse effects level, NOAEL) and 1."1.36Adverse effects of lactational exposure to chlorpyrifos in suckling rats. ( Mansour, SA; Mossa, AH, 2010)
"Both chlorpyrifos and cactus were administrated orally via gavages."1.35Opuntia ficus indica extract protects against chlorpyrifos-induced damage on mice liver. ( Akacha, A; Ben Othman, M; Krifi, MN; Ncibi, S; Zourgui, L, 2008)
"Chlorpyrifos treatment diminished serum and hepatic zinc levels significantly (p < 0."1.31Protective effects of zinc in chlorpyrifos induced hepatotoxicity: a biochemical and trace elemental study. ( Chauhan, DP; Dhawan, DK; Goel, A, 2000)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19902 (13.33)18.7374
1990's0 (0.00)18.2507
2000's2 (13.33)29.6817
2010's6 (40.00)24.3611
2020's5 (33.33)2.80

Authors

AuthorsStudies
Pei, H1
Liu, S1
Zeng, J1
Liu, J1
Wu, H1
Chen, W1
He, Z1
Du, R1
Roshanravan, B1
Farkhondeh, T1
Darroudi, M1
Samarghandian, S1
Nikbin, S1
Tajik, A1
Allahyari, P1
Matin, G1
Hoseini Roote, SS1
Barati, E1
Ayazi, M1
Karimi, L1
Dayani Yazdi, F1
Javadinejad, N1
Azarbayjani, MA1
Xun, ZM1
Xie, F1
Zhao, PX1
Liu, MY1
Li, ZY1
Song, JM1
Kong, XM1
Ma, XM1
Li, XY1
Kunnaja, P1
Chansakaow, S1
Wittayapraparat, A1
Yusuk, P1
Sireeratawong, S1
Zhang, J1
Liu, L1
Ren, L1
Feng, W1
Lv, P1
Wu, W1
Yan, Y1
Suke, SG1
Sherekar, P1
Kahale, V1
Patil, S1
Mundhada, D1
Nanoti, VM1
Albasher, G1
Almeer, R1
Al-Otibi, FO1
Al-Kubaisi, N1
Mahmoud, AM1
Malhotra, A1
Dhawan, DK2
Dokuyucu, R1
Bilgili, A1
Hanedan, B1
Dogan, H1
Dokuyucu, A1
Celik, MM1
Mansour, SA1
Mossa, AH1
Ncibi, S1
Ben Othman, M1
Akacha, A1
Krifi, MN1
Zourgui, L1
Costa, LG1
Murphy, SD1
Goel, A1
Chauhan, DP1
Popov, TA1
Zadorozhnaia, TD1

Reviews

1 review available for chlorpyrifos and Acute Liver Injury, Drug-Induced

ArticleYear
Current view of zinc as a hepatoprotective agent in conditions of chlorpyrifos induced toxicity.
    Pesticide biochemistry and physiology, 2014, Volume: 112

    Topics: Antioxidants; Chemical and Drug Induced Liver Injury; Chlorpyrifos; Environmental Exposure; Humans;

2014

Other Studies

14 other studies available for chlorpyrifos and Acute Liver Injury, Drug-Induced

ArticleYear
Ros-mediated mitochondrial oxidative stress is involved in the ameliorating effect of ginsenoside GSLS on chlorpyrifos-induced hepatotoxicity in mice.
    Aging, 2022, 09-22, Volume: 15, Issue:3

    Topics: Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Chlorpyrifos; Ginsenosides; Humans; I

2022
Protective Effect of Chrysin Against Chlorpyrifos-induced Hepatotoxicity in Rats: Biochemical and Histopathological Approaches in a Sub-chronic Study.
    Current pharmaceutical biotechnology, 2023, Volume: 24, Issue:10

    Topics: Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Chlorpyrifos; Flavonoids; Insecticide

2023
Aerobic exercise and eugenol supplementation ameliorated liver injury induced by chlorpyrifos via modulation acetylcholinesterase activation and antioxidant defense.
    Environmental toxicology, 2020, Volume: 35, Issue:7

    Topics: Acetylcholinesterase; Animals; Antioxidants; Catalase; Chemical and Drug Induced Liver Injury; Chlor

2020
Protective effects of molecular hydrogen on hepatotoxicity induced by sub-chronic exposure to chlorpyrifos in rats.
    Annals of agricultural and environmental medicine : AAEM, 2020, Sep-11, Volume: 27, Issue:3

    Topics: Animals; Chemical and Drug Induced Liver Injury; Chlorpyrifos; Dose-Response Relationship, Drug; Hyd

2020
In Vitro Antioxidant Activity of
    Molecules (Basel, Switzerland), 2021, Mar-28, Volume: 26, Issue:7

    Topics: Acetylcholinesterase; Alanine Transaminase; Alkaline Phosphatase; Animals; Antidotes; Antioxidants;

2021
The single and joint toxicity effects of chlorpyrifos and beta-cypermethrin in zebrafish (Danio rerio) early life stages.
    Journal of hazardous materials, 2017, Jul-15, Volume: 334

    Topics: Adherens Junctions; Animals; Antioxidants; Apoptosis; Catalase; Cell Cycle; Chemical and Drug Induce

2017
Ameliorative effect of nanoencapsulated flavonoid against chlorpyrifos-induced hepatic oxidative damage and immunotoxicity in Wistar rats.
    Journal of biochemical and molecular toxicology, 2018, Volume: 32, Issue:5

    Topics: Animals; Chemical and Drug Induced Liver Injury; Chlorpyrifos; Flavonoids; Liver; Male; Nanocapsules

2018
Ameliorative Effect of
    Biomolecules, 2019, 07-07, Volume: 9, Issue:7

    Topics: Animals; Antioxidants; Apoptosis; Beta vulgaris; Biomarkers; Chemical and Drug Induced Liver Injury;

2019
Attenuating effects of caffeic acid phenethyl ester with intralipid on hepatotoxicity of chlorpyrifos in the case of rats.
    Medycyna pracy, 2016, Dec-22, Volume: 67, Issue:6

    Topics: Animals; Antioxidants; Caffeic Acids; Chemical and Drug Induced Liver Injury; Chlorpyrifos; Immunoch

2016
Adverse effects of lactational exposure to chlorpyrifos in suckling rats.
    Human & experimental toxicology, 2010, Volume: 29, Issue:2

    Topics: Animals; Animals, Suckling; Biomarkers; Body Weight; Chemical and Drug Induced Liver Injury; Chlorpy

2010
Opuntia ficus indica extract protects against chlorpyrifos-induced damage on mice liver.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2008, Volume: 46, Issue:2

    Topics: Animals; Chemical and Drug Induced Liver Injury; Chlorpyrifos; Dose-Response Relationship, Drug; Ins

2008
Interaction between acetaminophen and organophosphates in mice.
    Research communications in chemical pathology and pharmacology, 1984, Volume: 44, Issue:3

    Topics: Acetaminophen; Animals; Brain; Chemical and Drug Induced Liver Injury; Chlorpyrifos; Cholinesterases

1984
Protective effects of zinc in chlorpyrifos induced hepatotoxicity: a biochemical and trace elemental study.
    Biological trace element research, 2000, Volume: 74, Issue:2

    Topics: Animals; Body Weight; Chemical and Drug Induced Liver Injury; Chlorpyrifos; Enzymes; Insecticides; M

2000
[Rhythmicity in the structure-functional changes in hepatocytes following exposure to pesticides].
    Biulleten' eksperimental'noi biologii i meditsiny, 1977, Volume: 83, Issue:3

    Topics: Alcoholic Intoxication; Animals; Azo Compounds; Biotransformation; Carbon Tetrachloride Poisoning; C

1977