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chlorpropamide and Pregnancy

chlorpropamide has been researched along with Pregnancy in 52 studies

Chlorpropamide: A sulfonylurea hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. (From Martindale, The Extra Pharmacopoeia, 30th ed, p277)
chlorpropamide : An N-sulfonylurea that is urea in which a hydrogen attached to one of the nitrogens is substituted by 4-chlorobenzenesulfonyl group and a hydrogen attached to the other nitrogen is substituted by propyl group. Chlorpropamide is a hypoglycaemic agent used in the treatment of type 2 (non-insulin-dependent) diabetes mellitus not responding to dietary modification.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

Excerpt	Relevance	Reference
") was used to diagnose chemical diabetes during pregnancy in 180 women, 50 of whom subsequently received chlorpropamide therapy in a daily dosage of 100 mg; the remainder had no drug therapy."	7.65	Evaluation of chlorpropamide in chemical diabetes diagnosed during pregnancy. ( Bewsher, PD; Cormack, JD; Stowers, JM; Sutherland, HW, 1973)
") was used to diagnose chemical diabetes during pregnancy in 180 women, 50 of whom subsequently received chlorpropamide therapy in a daily dosage of 100 mg; the remainder had no drug therapy."	3.65	Evaluation of chlorpropamide in chemical diabetes diagnosed during pregnancy. ( Bewsher, PD; Cormack, JD; Stowers, JM; Sutherland, HW, 1973)

Research

Studies (52)

Timeframe	Studies, this research(%)	All Research%
pre-1990	48 (92.31)	18.7374
1990's	3 (5.77)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (1.92)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
TUCHMANN-DUPLESSIS, H	1
MERCIER-PAROT, L	1
Straszewski-Chavez, SL	1
Abrahams, VM	1
Aldo, PB	1
Romero, R	1
Mor, G	1
JACKSON, WP	3
CAMPBELL, GD	2
NOTELOVITZ, M	4
BLUMSOHN, D	1
BEISCHER, NA	1
LOWRY, J	1
POULSEN, JE	1
LOPEZFERNANDEZ, RJ	1
MERCHANTE, FR	1
CAGLI, V	1
MALINS, JM	2
COOKE, AM	1
PYKE, DA	2
FITZGERALD, MG	1
MOSS, JM	1
DELAWTER, DE	1
GALLAGHER, EJ	1
PANTELAKIS, SN	1
CAMERON, AH	1
DAVIDSON, S	1
DUNN, PM	1
FOSBROOKE, AS	1
LLOYD, JK	1
WOLFF, OH	1
KEEN, H	1
Douglas, CP	1
Richards, R	1
Barnett, AH	1
Spiliopoulos, AJ	1
MacDonald, MJ	1
Uhrig, JD	1
Hurley, RM	1
Calvani, M	1
Di Maio, C	1
Ghirelli, D	1
Robinson, AG	2
Verbalis, JG	1
Elliott, BD	1
Schenker, S	1
Langer, O	1
Johnson, R	1
Prihoda, T	1
Watson, WA	1
Petrie, JC	1
Galloway, DB	1
Bullock, I	1
Gilbert, JC	1
Tulloch, JA	1
Adamson, DG	1
Brearley, BF	1
Gill, G	1
Stowers, JM	6
Sutherland, HW	3
Kerridge, DF	1
Tattersall, RB	1
Frantz, AG	1
Vangen, O	1
Cormack, JD	2
Bewsher, PD	2
Wachholz, DE	1
Wahlstrom, RC	1
Sheldon, J	1
Coleman, T	1
Sutherland, H	2
Russell, G	2
Fisher, PM	1
Hughes, CR	1
Reid, A	1
Assemany, SR	1
Muzzo, S	1
Gardner, LI	1
Harris, EL	1
Heisig, N	2
Battaglia, RA	1
Meacham, TN	1
Kemball, ML	1
McIver, C	1
Milner, RD	1
Nourse, CH	1
Schiff, D	1
Tiernan, JR	1
Edwards, CR	1
Farquhar, JW	1
Isles, TE	1
Zucker, P	1
Simon, G	1
Kenmure, AC	1

Reviews

4 reviews available for chlorpropamide and Pregnancy

Article	Year
[Monitoring and treatment of diabetic fetopathy]. Recenti progressi in medicina, 1982, Volume: 72, Issue:3 Topics: Adult; Chlorpropamide; Congenital Abnormalities; Diabetes Mellitus; Female; Fetal Death; Fetal Disea	1982
Practical management of diabetes in the tropics. Tropical doctor, 1990, Volume: 20, Issue:1 Topics: Blood Glucose; Chlorpropamide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucose	1990
Radioimmunoassay of posterior pituitary peptides: a review. Metabolism: clinical and experimental, 1973, Volume: 22, Issue:8 Topics: Adult; Animals; Antibody Formation; Cattle; Chlorpropamide; Diabetes Insipidus; Female; Fetus; Goats	1973
Glibenclamide: a review. Drugs, 1971, Volume: 1, Issue:2 Topics: Administration, Oral; Adolescent; Adult; Aged; Animals; Biguanides; Blood Glucose; Carbon Isotopes;	1971

Trials

1 trial available for chlorpropamide and Pregnancy

Article	Year
Sulphonylurea therapy in the treatment of the pregnant diabetic. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1971, Feb-27, Volume: 45, Issue:9 Topics: Abnormalities, Drug-Induced; Adult; Apgar Score; Blood Glucose; Chlorpropamide; Diet Therapy; Female	1971

Other Studies

47 other studies available for chlorpropamide and Pregnancy

Article	Year
[Action of chlorpropamide, a hypoglycemic sulfonamide, on gestation and fetal development in the rat]. Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1959, Sep-28, Volume: 249 Topics: Animals; Chlorpropamide; Female; Fetal Development; Fetus; Hypoglycemic Agents; Pregnancy; Rats; Sul	1959
AKT controls human first trimester trophoblast cell sensitivity to FAS-mediated apoptosis by regulating XIAP expression. Biology of reproduction, 2010, Volume: 82, Issue:1 Topics: Apoptosis; Caspase 3; Cell Line; Chlorpropamide; Chromones; Down-Regulation; fas Receptor; Female; H	2010
Tolbutamide and chlorpropamide during pregnancy in human diabetics. Diabetes, 1962, Volume: 11(Suppl) Topics: Carbutamide; Chlorpropamide; Diabetes Mellitus; Female; Pregnancy; Pregnancy Complications; Tolbutam	1962
CHLORPROPAMIDE AND PERINATAL MORTALITY. British medical journal, 1963, Dec-28, Volume: 2, Issue:5373 Topics: Abnormalities, Drug-Induced; Chlorpropamide; Female; Infant Mortality; Infant, Newborn; Perinatal De	1963
THE DETECTION AND MANAGEMENT OF ABNORMAL GLUCOSE TOLERANCE DURING PREGNANCY. The Journal of obstetrics and gynaecology of the British Commonwealth, 1963, Volume: 70 Topics: Chlorpropamide; Cortisone; Diabetes Mellitus; Disease Management; Female; Glucose; Glucose Intoleran	1963
[ORAL DIABETIC DRUGS]. Nordisk medicin, 1964, Feb-20, Volume: 71 Topics: Carbutamide; Chlorpropamide; Diabetes Mellitus; Female; Humans; Metformin; Phenformin; Pregnancy; Pr	1964
[VARIANTS OF THE PRE-DIABETIC STATE IN PREGNANCY]. Toko-ginecologia practica, 1963, Volume: 22 Topics: Chlorpropamide; Diabetes Mellitus; Female; Prediabetic State; Pregnancy; Pregnancy in Diabetics; Pro	1963
[PREDIABETES AND PREGNANCY]. La Semana medica, 1963, Oct-24, Volume: 123 Topics: Anesthesia; Anesthesia, Obstetrical; Chlorpropamide; Diabetes Mellitus; Diet; Diet Therapy; Female;	1963
[THE THERAPY OF DIABETES MELLITUS]. Il Policlinico. Sezione pratica, 1964, Jan-06, Volume: 71 Topics: Carbutamide; Chlorpropamide; Diabetes Mellitus; Diabetic Coma; Diet, Diabetic; Female; Globins; Hypo	1964
SULPHONYLUREA DRUGS IN PREGNANCY. British medical journal, 1964, Jul-18, Volume: 2, Issue:5402 Topics: Abnormalities, Drug-Induced; Chlorpropamide; Diabetes Mellitus; Female; Fetal Death; Humans; Pregnan	1964
ORAL HYPOGLYCEMIC DRUGS: COMPARATIVE EVALUATION OF TOLBUTAMIDE, CHLORPROPAMIDE AND PHENFORMIN. Medical times, 1964, Volume: 92 Topics: Alkaline Phosphatase; Biomedical Research; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Diabete	1964
THE DIABETIC PREGNANCY. A STUDY OF SERUM LIPIDS IN MATERNAL AND UMBILICAL CORD BLOOD AND OF THE UTERINE AND PLACENTAL VASCULATURE. Archives of disease in childhood, 1964, Volume: 39 Topics: Abortion, Induced; Blood Chemical Analysis; Cesarean Section; Chlorpropamide; Cholesterol; Diabetes	1964
THE FAMILY DOCTOR AND THE DIABETIC. The Practitioner, 1965, Volume: 194 Topics: Acidosis; Adolescent; Child; Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetic	1965
Use of chlorpropamide in the treatment of diabetes in pregnancy. Diabetes, 1967, Volume: 16, Issue:1 Topics: Chlorpropamide; Diabetes Mellitus; Female; Humans; Pregnancy; Pregnancy in Diabetics	1967
Blockade of chlorpropamide-alcohol flushing by indomethacin suggests an association between prostaglandins and diabetic vascular complications. Lancet (London, England), 1980, Jul-26, Volume: 2, Issue:8187 Topics: Blood Vessels; Chlorpropamide; Diabetes Mellitus; Diabetic Angiopathies; Ethanol; Face; Female; Huma	1980
Etiology and classification of diabetes in children. Practical genetics and prognosis counseling. Primary care, 1983, Volume: 10, Issue:4 Topics: Adolescent; Adult; Animals; Child; Child, Preschool; Chlorpropamide; Diabetes Mellitus, Type 1; Diab	1983
Chlorpropamide in pregnancy and transient neonatal diabetes insipidus. Canadian Medical Association journal, 1983, Feb-15, Volume: 128, Issue:4 Topics: Adult; Chlorpropamide; Diabetes Insipidus; Female; Humans; Infant, Newborn; Infant, Newborn, Disease	1983
Diabetes insipidus. Current therapy in endocrinology and metabolism, 1994, Volume: 5 Topics: Benzothiadiazines; Carbamazepine; Chlorpropamide; Clofibrate; Diabetes Insipidus; Diuretics; Female;	1994
Comparative placental transport of oral hypoglycemic agents in humans: a model of human placental drug transfer. American journal of obstetrics and gynecology, 1994, Volume: 171, Issue:3 Topics: Administration, Oral; Analysis of Variance; Antipyrine; Biological Transport; Chlorpropamide; Chroma	1994
In vivo cytogenetic activity of sulphonylurea drugs in man. Mutation research, 1976, Volume: 38, Issue:1 Topics: Adult; Chlorpropamide; Chromosome Aberrations; Chromosome Deletion; Diabetes Mellitus; Female; Glybu	1976
Dominant inheritance diabetes mellitus. Journal of the Royal College of Physicians of London, 1976, Volume: 11, Issue:1 Topics: Adolescent; Adult; Aged; Chlorpropamide; Diabetes Mellitus; Female; Genes, Dominant; Genotype; Gluco	1976
The management of pregnancy in diabetes mellitus. The Practitioner, 1975, Volume: 215, Issue:1289 Topics: Birth Weight; Blood Glucose; Chlorpropamide; Delivery, Obstetric; Diet, Diabetic; Female; Fetal Deat	1975
Long-range implications for the mother. The Aberdeen experience. Diabetes, 1985, Volume: 34 Suppl 2 Topics: Adolescent; Adult; Autoantibodies; Blood Glucose; Chlorpropamide; Fasting; Female; Follow-Up Studies	1985
Editorial: Chlorpropamide in diabetic pregnancy. Lancet (London, England), 1974, Jul-06, Volume: 2, Issue:7871 Topics: Abnormalities, Drug-Induced; Chlorpropamide; Female; Humans; Infant, Newborn; Maternal-Fetal Exchang	1974
Letter: Oral hypoglycaemic therapy in diabetic pregnancies. Lancet (London, England), 1974, Oct-12, Volume: 2, Issue:7885 Topics: Administration, Oral; Antigens; Biguanides; Blood Glucose; Chlorpropamide; Female; Humans; Insulin;	1974
Letter: Chlorpropamide in diabetic pregnancy. Lancet (London, England), 1974, Oct-05, Volume: 2, Issue:7884 Topics: Chlorpropamide; Female; Humans; Infant; Infant Mortality; Infant, Newborn; Maternal-Fetal Exchange;	1974
Mild familial diabetes with dominant inheritance. The Quarterly journal of medicine, 1974, Volume: 43, Issue:170 Topics: Acetohexamide; Adolescent; Adult; Aged; Blood Glucose; Carbohydrates; Child; Chlorpropamide; Diabete	1974
[Diabetes insipidus and pregnancy]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1972, Nov-10, Volume: 92, Issue:31 Topics: Adult; Amenorrhea; Chlorpropamide; Diabetes Insipidus; Female; Follow-Up Studies; Humans; Lactation	1972
Evaluation of chlorpropamide in chemical diabetes diagnosed during pregnancy. British medical journal, 1973, Jul-07, Volume: 3, Issue:5870 Topics: Birth Weight; Blood Glucose; Chlorpropamide; Female; Fetal Death; Fetus; Glucose; Glucose Tolerance	1973
Effect of chlorpropamide on gravid swine and blood glucose and fructose in the fetal pig. Journal of animal science, 1973, Volume: 37, Issue:1 Topics: Administration, Oral; Animal Feed; Animals; Blood Glucose; Body Weight; Chlorpropamide; Corpus Luteu	1973
Remission of diabetes mellitus during pregnancy. British medical journal, 1974, Jan-12, Volume: 1, Issue:5897 Topics: Adult; Birth Weight; Blood Glucose; Body Weight; Chlorpropamide; Diet Therapy; Female; Glucose Toler	1974
Letter: Remission of diabetes during pregnancy. British medical journal, 1974, Mar-02, Volume: 1, Issue:5904 Topics: Blood Glucose; Chlorpropamide; Female; Humans; Infant Mortality; Pregnancy; Pregnancy in Diabetics	1974
Letter: Gestational diabetes. British medical journal, 1974, Mar-30, Volume: 1, Issue:5908 Topics: Chlorpropamide; Female; Glucose Tolerance Test; Humans; Pregnancy; Pregnancy in Diabetics	1974
Effect of moderate dosage of chlorpropamide in pregnancy on fetal outcome. Archives of disease in childhood, 1974, Volume: 49, Issue:4 Topics: Adult; Apgar Score; Birth Weight; Blood; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Female; F	1974
Treatment of subclinical diabetes. Advances in metabolic disorders, 1970, Volume: 1 Topics: Adult; Age Factors; Aged; Chlorpropamide; Female; Glycosuria; Humans; Hyperplasia; Hypoglycemic Agen	1970
Syndrome of phocomelic diabetic embryopathy (caudal dysplasia). American journal of diseases of children (1960), 1972, Volume: 123, Issue:5 Topics: Abnormalities, Multiple; Adolescent; Chlordiazepoxide; Chlorpropamide; Ectromelia; Female; Humans; I	1972
Adverse reactions to oral antidiabetic agents. British medical journal, 1971, Jul-03, Volume: 3, Issue:5765 Topics: Acetohexamide; Acidosis; Administration, Oral; Anemia; Chlorpropamide; Drug Antagonism; Drug Synergi	1971
[Critical reflections on the present status or oral diabetes therapy in pregnancy]. Archiv fur Gynakologie, 1971, Jun-04, Volume: 211, Issue:1 Topics: Administration, Oral; Biguanides; Carbutamide; Chlorpropamide; Female; Humans; Hypoglycemic Agents;	1971
Seminars on diabetes. II. Principles of management. Canadian Medical Association journal, 1971, Volume: 105, Issue:9 Topics: Acetohexamide; Chlorpropamide; Diabetes Mellitus; Diet, Diabetic; Female; Health Education; Humans;	1971
Effect of chlorpropamide upon prenatal losses in rabbits. Biology of reproduction, 1969, Volume: 1, Issue:3 Topics: Animals; Birth Weight; Blood Glucose; Chlorpropamide; Embryo Implantation; Female; Fetal Death; Male	1969
Neonatal hypoglycaemia in infants of diabetic mothers given sulphonylurea drugs in pregnancy. Archives of disease in childhood, 1970, Volume: 45, Issue:243 Topics: Acetohexamide; Chlorpropamide; Exchange Transfusion, Whole Blood; Female; Fetus; Humans; Hypoglycemi	1970
Measurement of plasma and urinary vasopressin by immunoassay. Proceedings of the Royal Society of Medicine, 1971, Volume: 64, Issue:8 Topics: Animals; Biological Assay; Bronchial Neoplasms; Carcinoma, Bronchogenic; Chlorpropamide; Diabetes In	1971
[Oral antidiabetics in pregnancy]. Medizinische Klinik, 1971, Mar-19, Volume: 66, Issue:12 Topics: Abnormalities, Drug-Induced; Biguanides; Carbutamide; Chlorpropamide; Female; Fetus; Humans; Hypogly	1971
Hypoglycemia in newborn infants of normal and diabetic mothers. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1968, Mar-09, Volume: 42, Issue:10 Topics: Blood Glucose; Chlorpropamide; Female; Glucose; Humans; Hypoglycemia; Infant, Newborn; Infant, Newbo	1968
Prolonged symptomatic neonatal hypoglycemia associated with maternal chlorpropamide therapy. Pediatrics, 1968, Volume: 42, Issue:5 Topics: Adult; Chlorpropamide; Exchange Transfusion, Whole Blood; Female; Humans; Hypoglycemia; Infant, Newb	1968
Pregnancy in a patient with a prosthetic mitral valve. The Journal of obstetrics and gynaecology of the British Commonwealth, 1968, Volume: 75, Issue:5 Topics: Adult; Chlorpropamide; Digoxin; Female; Fetal Death; Furosemide; Gestational Age; Heart Valve Prosth	1968
The adrenal cortex and the pregnant diabetic. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1969, Aug-09, Volume: 43, Issue:32 Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Glands; Adult; Chlorpropamide; Diabe	1969