chlorpropamide has been researched along with Porphyrias in 5 studies
Chlorpropamide: A sulfonylurea hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. (From Martindale, The Extra Pharmacopoeia, 30th ed, p277)
chlorpropamide : An N-sulfonylurea that is urea in which a hydrogen attached to one of the nitrogens is substituted by 4-chlorobenzenesulfonyl group and a hydrogen attached to the other nitrogen is substituted by propyl group. Chlorpropamide is a hypoglycaemic agent used in the treatment of type 2 (non-insulin-dependent) diabetes mellitus not responding to dietary modification.
Porphyrias: A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| KNOX, JM | 1 |
| ZAROWITZ, H | 1 |
| NEWHOUSE, S | 1 |
| Streda, M | 1 |
| De Matteis, F | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evidence-based Assessment of Medication Sensitivity in Acute Hepatic Porphyria[NCT03906214] | 60 participants (Actual) | Observational | 2019-04-03 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for chlorpropamide and Porphyrias
| Article | Year |
|---|---|
Glucose tolerance tests in the clinical picture of chronic liver diseases.
Topics: Adolescent; Adult; Age Factors; Aged; Alanine Transaminase; Aspartate Aminotransferases; Body Weight | 1975 |
Toxic hepatic porphyrias.
Topics: Alcoholism; Antifungal Agents; Chemical and Drug Induced Liver Injury; Chlorpropamide; Hexachlorocyc | 1968 |
Disturbances of liver porphyrin metabolism caused by drugs.
Topics: Animals; Chlorpropamide; Drug-Related Side Effects and Adverse Reactions; Estrogens; Griseofulvin; H | 1967 |
2 other studies available for chlorpropamide and Porphyrias
| Article | Year |
|---|---|
PHOTOSENSITIVITY--A COMMON PHYSICAL ALLERGY.
Topics: 4-Aminobenzoic Acid; Aminobenzoates; Anti-Bacterial Agents; Antimalarials; Chlorothiazide; Chlorprop | 1964 |
COPROPORPHYRINURIA WITH A CUTANEOUS REACTION INDUCED BY CHLORPROPAMIDE.
Topics: Chlorpropamide; Coproporphyria, Hereditary; Diabetes Mellitus; Porphyrias; Toxicology | 1965 |