Page last updated: 2024-10-25

chlorpropamide and Parkinson Disease

chlorpropamide has been researched along with Parkinson Disease in 3 studies

Chlorpropamide: A sulfonylurea hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. (From Martindale, The Extra Pharmacopoeia, 30th ed, p277)
chlorpropamide : An N-sulfonylurea that is urea in which a hydrogen attached to one of the nitrogens is substituted by 4-chlorobenzenesulfonyl group and a hydrogen attached to the other nitrogen is substituted by propyl group. Chlorpropamide is a hypoglycaemic agent used in the treatment of type 2 (non-insulin-dependent) diabetes mellitus not responding to dietary modification.

Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Majid, N1
Siddiqi, MK1
Hassan, MN1
Malik, S1
Khan, S1
Khan, RH1
BARRINGTON, PC1
Ahmed, I1
Ahmad, B1
Hussain, MF1

Trials

1 trial available for chlorpropamide and Parkinson Disease

ArticleYear
The use of chlorpropamide in the treatment of Parkinsonism.
    The British journal of clinical practice, 1968, Volume: 22, Issue:7

    Topics: Adult; Aged; Chlorpropamide; Female; Humans; Male; Middle Aged; Parkinson Disease

1968

Other Studies

2 other studies available for chlorpropamide and Parkinson Disease

ArticleYear
Inhibition of primary and secondary nucleation alongwith disruption of amyloid fibrils and alleviation of associated cytotoxicity: A biophysical insight of a novel property of Chlorpropamide (an anti-diabetic drug).
    Biomaterials advances, 2023, Volume: 151

    Topics: Amyloid; Amyloidogenic Proteins; Amyloidosis; Chlorpropamide; Humans; Parkinson Disease

2023
CHLORPROPAMIDE IN PARKINSON'S DISEASE.
    Bristol medico-chirurgical journal (1963), 1964, Volume: 79

    Topics: Biomedical Research; Chlorpropamide; Drug Therapy; Humans; Parkinson Disease; Parkinsonian Disorders

1964