Page last updated: 2024-10-25

chlorpropamide and Obesity

chlorpropamide has been researched along with Obesity in 41 studies

Chlorpropamide: A sulfonylurea hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. (From Martindale, The Extra Pharmacopoeia, 30th ed, p277)
chlorpropamide : An N-sulfonylurea that is urea in which a hydrogen attached to one of the nitrogens is substituted by 4-chlorobenzenesulfonyl group and a hydrogen attached to the other nitrogen is substituted by propyl group. Chlorpropamide is a hypoglycaemic agent used in the treatment of type 2 (non-insulin-dependent) diabetes mellitus not responding to dietary modification.

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

Excerpt	Relevance	Reference
"In patients with type 2 diabetes, intensive blood-glucose control with insulin or sulphonylurea therapy decreases progression of microvascular disease and may also reduce the risk of heart attacks."	2.69	Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. ( , 1998)

Research

Studies (41)

Timeframe	Studies, this research(%)	All Research%
pre-1990	36 (87.80)	18.7374
1990's	4 (9.76)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (2.44)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Ito, M	1
Nagasawa, M	1
Omae, N	1
Ide, T	1
Akasaka, Y	1
Murakami, K	1
FINEBERG, SK	2
SEFTEL, HC	1
KEELEY, KJ	1
TEITELBAUM, M	1
LEMARCHANT, JM	1
LINQUETTE, M	1
FOSSATI, P	1
GASNAULT, JP	1
RACADOT, A	1
MOSS, JM	1
DELAWTER, DE	1
GALLAGHER, EJ	1
SALANS, LB	1
REAVEN, GM	2
CONTE, M	1
FOUET, P	1
LIGUORY, C	1
BENNER, EJ	1
PARTRIDGE, JW	1
HOLCOMB, B	1
Awoke, S	1
Voyles, NR	1
Bhathena, SJ	1
Tanenberg, RJ	1
Recant, L	1
Scott, CR	1
Frindik, JP	1
Kemp, SF	1
Kearns, GL	1
Cudworth, AG	1
Holman, RR	1
Turner, RC	1
Sauer, H	1
Schneider, B	1
Bernard, DB	1
Stowers, JM	2
Sutherland, HW	1
Kerridge, DF	1
Clarke, BF	1
Duncan, LJ	1
Butterfield, WJ	1
Whichelow, MJ	1
Mashaly, M	1
el-Ebrashy, N	1
Higazi, AM	1
Einen, MA	1
Aziz, MT	1
Steel, JM	1
Mngola, EN	1
Bloom, A	3
Chu, PC	1
Conway, MJ	1
Krouse, HA	1
Goodner, CJ	1
Jackson, WP	1
Bricker, LA	1
Mintz, DH	1
Lev-Ran, AS	1
Tomkins, AM	1
Brodribb, HS	1
Bode, HH	1
Harley, BM	1
Crawford, JD	1
Arky, RA	2
Abramson, EA	1
Abramson, E	1
Bruns, W	1
Michaelis, D	1
Wappler, E	1
Rigas, AN	1
Bittles, AH	1
Hadden, DR	1
Montgomery, DA	1
Yamagata, S	1
Goto, Y	1
Oneda, A	1
Kikuchi, J	1
Toyota, T	1

Clinical Trials (13)

Trial Overview

Trial	Phase	Enrollment	Study Type	Start Date	Status
A Randomized Phase 3 Trial of Metformin in Patients Initiating Androgen Deprivation Therapy as Prevention and Intervention of Metabolic Syndrome: The Prime Study[NCT03031821]	Phase 3	168 participants (Actual)	Interventional	2018-07-12	Terminated (stopped due to Manufacturer discontinued the production of study drugs.)
Financial Incentives and SMS to Improve African American Womens' Glycemic Control: Friends & Relatives Improving the Effectiveness of Networks for Diabetes Support Through Text Messaging (FRIENDS Text)[NCT02384265]		41 participants (Actual)	Interventional	2012-06-21	Completed
A Randomized, Multi-Center, Pivotal Efficacy and Safety Study Evaluating the EndoBarrier® System for Glycemic Improvement in Patients With Inadequately Controlled Type 2 Diabetes and Obesity[NCT04101669]		240 participants (Anticipated)	Interventional	2019-09-09	Recruiting
Effect of Metformin Glycinate on Postprandial Lipemia, Glycemic Control and Oxidation Markers in Type 2 Diabetes Patients[NCT02064881]	Phase 2/Phase 3	72 participants (Anticipated)	Interventional	2015-10-31	Recruiting
A Pilot Study to Evaluate Eli Lilly's Insulin Dosing Algorithm to Control Glycemia in Insulin-treated Adults With Type 2 Diabetes[NCT05514080]		10 participants (Actual)	Interventional	2019-12-06	Completed
A 16-wk, Uni-center, Randomized, Double-blind, Parallel, Phase 3b Trial to Evaluate Efficacy of Saxagliptin + Dapagliflozin vs.Dapagliflozin With Regard to EGP in T2DM With Insufficient Glycemic Control on Metformin+/-Sulfonylurea Therapy[NCT02613897]		56 participants (Actual)	Interventional	2016-01-31	Completed
The TELE-DD Project: a Nurse-led Randomised Controlled Trial on Treatment Adherence in Patients With Type 2 Diabetes and Comorbid Depression[NCT04097483]		428 participants (Actual)	Interventional	2017-01-31	Completed
Metformin Pharmacology in Human Cancers[NCT03477162]	Early Phase 1	18 participants (Actual)	Interventional	2018-05-15	Terminated (stopped due to Enrollment was closed as efforts had become more challenging, and the lab indicated that they were able to obtain their primary objective with the number that had already been enrolled.)
Does Glycated Hemoglobin Variability in Type 2 Diabetes Differ Depending on the Diabetes Treatment Threshold Used in the Qatari Population: Implication on Diabetes Complication Risk?[NCT02879409]		150 participants (Anticipated)	Interventional	2016-11-30	Active, not recruiting
The Effects of Metformin on Vascular Structure and Function in Subjects With the Metabolic Syndrome (MET Trial)[NCT00105066]	Phase 2	77 participants (Actual)	Interventional	2004-01-31	Completed
The Assessment of the Effect of Metformin and Its Serum Concentration on the Concentration of Substances Associated With the Production of Nitric Oxide in Patients With Impaired Carbohydrate Metabolism[NCT03398356]	Phase 4	47 participants (Actual)	Interventional	2017-10-20	Completed
Efficacy and Safety of Metformin Glycinate Compared to Metformin Hydrochloride on the Progression of Type 2 Diabetes[NCT04943692]	Phase 3	500 participants (Anticipated)	Interventional	2021-08-31	Suspended (stopped due to Administrative decision of the investigation direction)
Safety and Efficacy of Metformin Glycinate vs Metformin Hydrochloride on Metabolic Control and Inflammatory Mediators in Type 2 Diabetes Patients[NCT01386671]	Phase 3	203 participants (Actual)	Interventional	2014-06-30	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in BMI

Change in BMI (body mass index) from study start to 16 weeks (NCT02613897)
Timeframe: Change from baseline to 16 weeks

Intervention	Kg/m^2 (Mean)
DAPA/SAXA (Dapagliflozin Plus Saxagliptin)	-0.8
DAPA (Dapagliflozin Plus Placebo)	-0.66
PCB (Placebo Plus Placebo)	0.16

Change in Body Weight

Change in body weight from baseline to 16 weeks (NCT02613897)
Timeframe: Baseline to 16 weeks

Intervention	Kg (Mean)
DAPA/SAXA (Dapagliflozin Plus Saxagliptin)	-2.28
DAPA (Dapagliflozin Plus Placebo)	-1.76
PCB (Placebo Plus Placebo)	0.26

Change in Fasting Plasma Glucagon (FPG)

A measure of the change in fasting plasma glucagon from study start to 16 weeks (NCT02613897)
Timeframe: Change from baseline to 16 weeks

Intervention	mg/dl (Mean)
DAPA/SAXA (Dapagliflozin Plus Saxagliptin)	-28.52
DAPA (Dapagliflozin Plus Placebo)	26.89
PCB (Placebo Plus Placebo)	6.88

Change in Free Fatty Acids (FFA)

Measure of change in Free Fatty Acids from study start to 16 weeks (NCT02613897)
Timeframe: Change from baseline to 16 weeks

Intervention	mEq/L (Mean)
DAPA/SAXA (Dapagliflozin Plus Saxagliptin)	-0.06
DAPA (Dapagliflozin Plus Placebo)	-0.01
PCB (Placebo Plus Placebo)	0.00

Change in Glucose Oxidation

Change in percentage of glucose oxidation from study start to 16 weeks (NCT02613897)
Timeframe: Change from baseline to 16 weeks

Intervention	percentage of oxidation (Mean)
DAPA/SAXA (Dapagliflozin Plus Saxagliptin)	-22.07
DAPA (Dapagliflozin Plus Placebo)	-46.54
PCB (Placebo Plus Placebo)	4.65

Change in Lipid Oxidation

Change in lipid oxidation percentage from baseline to 16 weeks (NCT02613897)
Timeframe: Change from baseline to 16 weeks

Intervention	percentage of oxidation (Mean)
DAPA/SAXA (Dapagliflozin Plus Saxagliptin)	-11.87
DAPA (Dapagliflozin Plus Placebo)	22.02
PCB (Placebo Plus Placebo)	-6.69

HBA1c

Change in blood glucose level measured over a 3 month period from study start to 16 weeks (NCT02613897)
Timeframe: Change from baseline to 16 weeks

Intervention	percentage change in blood glucose level (Mean)
DAPA/SAXA (Dapagliflozin Plus Saxagliptin)	-1.67
DAPA (Dapagliflozin Plus Placebo)	-1.46
PCB (Placebo Plus Placebo)	0.44

Mean Oral Glucose Tolerance Test (OGTT)

Measure of change in OGTT from study start to 16 weeks (NCT02613897)
Timeframe: Change from baseline to 16 weeks

Intervention	mg/dl (Mean)
DAPA/SAXA (Dapagliflozin Plus Saxagliptin)	-49.62
DAPA (Dapagliflozin Plus Placebo)	-44.24
PCB (Placebo Plus Placebo)	20.26

Change in Endogenous Glucose Production (EGP)

All subjects received a Double-Tracer Oral Glucose Tolerance Test (OGTT) with 75g of glucose containing 14C-glucose together with intravenous primed-continuous infusion of 3(3H)-glucose for 240 minutes, at baseline (prior to) and after 16 weeks of therapy. Blood and urine samples were obtained during the OGTT to determine EGP. (NCT02613897)
Timeframe: Baseline and 16 weeks

Intervention	mg/kg*min (Mean)
	Baseline Measurement	16 weeks
DAPA (Dapagliflozin Plus Placebo)	2.56	2.8
DAPA/SAXA (Dapagliflozin Plus Saxagliptin)	2.45	2.4
PCB (Placebo Plus Placebo)	1.95	2.15

Concentration of Metformin in Adipose Tissue

To determine the concentration of metformin in adipose tissue. (NCT03477162)
Timeframe: Within 7 days from surgery

Intervention	ng/g (Median)
Metformin	70

Concentration of Metformin in Plasma.

To determine the concentration of metformin in plasma. (NCT03477162)
Timeframe: Within 7 days from surgery

Intervention	ng/mL (Median)
Metformin	450

Concentration of Metformin in Tumor-adjacent Normal Tissue

To determine the concentration of metformin in tumor-adjacent normal tissue. (NCT03477162)
Timeframe: Within 7 days from surgery

Intervention	ng/g (Median)
Metformin	749

Concentration of Metformin in Whole Blood.

To determine the concentration of metformin in whole blood. (NCT03477162)
Timeframe: Within 7 days from surgery

Intervention	ng/mL (Median)
Metformin	514

Lung Tumor Tissue Concentration of Metformin

To determine the intra-tumor concentrations of metformin, with a standard deviation ≤25% of the mean, in patients with solid tumors of thoracic origin administered metformin extended release. (NCT03477162)
Timeframe: Within 7 days from surgery

Intervention	ng/g (Median)
Metformin	1290

Change in Arterial Stiffness Compared to Baseline

(NCT00105066)
Timeframe: Baseline and 4.5 months

Intervention	meters / second (Mean)
Placebo	-7.2
Metformin	-7.3

Change in Flow Mediated Dilation (FMD)

to evaluate improvement in endothelial function (NCT00105066)
Timeframe: Baseline and 4.5 months

Intervention	percentage change in diameter (Mean)
Placebo	8.8
Metformin	10.5

Homa Insulin Sensitivity

Homeostatic Model Assessment of insulin sensitivity (NCT00105066)
Timeframe: 4.5 months

Intervention	HOMA Score (Mean)
Placebo	57.4
Metformin	64.5

Serum Levels of ADMA at Different Time Points

ADMA- asymmetric dimethylarginine-serum concentration (NCT03398356)
Timeframe: before study start; 6 weeks from treatment start; 12 weeks from treatment start; 15 weeks from treatment start

Intervention	µM (Mean)
	6 weeks from the start of treatment	12 weeks from the start of treatment	15 weeks from the start of treatment
Group A	0.51	0.52	0.50
Group B	0.57	0.55	0.52

Serum Levels of Arginine at Different Time Points

arginine serum concentration (NCT03398356)
Timeframe: Baseline; 6 weeks from treatment start; 12 weeks from treatment start; 15 weeks from treatment start

Intervention	µM (Mean)
	6 weeks from the start of treatment	12 weeks from the start of treatment	15 weeks from the start of treatment
Group A	112.18	107.72	104.72
Group B	111.72	97.69	103.76

Serum Levels of Citrulline at Different Time Points

serum concentration of the citrulline (NCT03398356)
Timeframe: Baseline; 6 weeks from treatment start; 12 weeks from treatment start; 15 weeks from treatment start

Intervention	µM (Mean)
	6 weeks from the start of treatment	12 weeks from the start of treatment	15 weeks from the start of treatment
Group A	21.73	25.95	26.93
Group B	28.08	27.01	29.77

Serum Levels of DMA at Different Time Points

DMA- dimethylamine, serum concentration (NCT03398356)
Timeframe: Baseline; 6 weeks from treatment start; 12 weeks from treatment start; 15 weeks from treatment start

Intervention	µM (Mean)
	6 weeks from the start of treatment	12 weeks from the start of treatment	15 weeks from the start of treatment
Group A	1.71	1.63	1.62
Group B	2.07	1.89	1.84

Serum Levels of Metformin at Different Time Points

the serum concentration of the studied drug-metformin (NCT03398356)
Timeframe: 6 weeks from treatment start; 12 weeks from treatment start; 15 weeks from treatment start

Intervention	µM (Mean)
	6 weeks from the start of treatment	12 weeks from the start of treatment	15 weeks from the start of treatment
Group A	4.36	5.09	4.66
Group B	4.25	7.42	4.01

Serum Levels of SDMA at Different Time Points

SDMA-symmetric dimethylarginine-serum concentration (NCT03398356)
Timeframe: Baseline; 6 weeks from treatment start; 12 weeks from treatment start; 15 weeks from treatment start

Intervention	µM (Mean)
	6 weeks from the start of treatment	12 weeks from the start of treatment	15 weeks from the start of treatment
Group A	0.40	0.41	0.39
Group B	0.45	0.42	0.39

Reviews

4 reviews available for chlorpropamide and Obesity

Article	Year
[What is achieved by the therapy with oral antidiabetics?]. Der Internist, 1976, Volume: 17, Issue:12 Topics: Administration, Oral; Adult; Biguanides; Chlorpropamide; Diabetes Mellitus; Diabetic Angiopathies; D	1976
Oral treatment in diabetes. Clinics in endocrinology and metabolism, 1972, Volume: 1, Issue:3 Topics: Acetohexamide; Acidosis; Administration, Oral; Animals; Biguanides; Cardiovascular Diseases; Chlorpr	1972
Oral sulphonylureas in the management of diabetes. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1971, Jan-30, Volume: 45, Issue:5 Topics: Acetohexamide; Chlorpropamide; Cyclohexanes; Diabetes Mellitus; Endocrine Glands; Glucose Tolerance	1971
Insulin-independent diabetes mellitus. The Medical clinics of North America, 1971, Volume: 55, Issue:2 Topics: Acetohexamide; Adult; Age Factors; Aged; Basement Membrane; Capillaries; Carbohydrate Metabolism, In	1971

Trials

8 trials available for chlorpropamide and Obesity

Article	Year
United Kingdom Prospective Diabetes Study (UKPDS). 13: Relative efficacy of randomly allocated diet, sulphonylurea, insulin, or metformin in patients with newly diagnosed non-insulin dependent diabetes followed for three years. BMJ (Clinical research ed.), 1995, Jan-14, Volume: 310, Issue:6972 Topics: Adult; Aged; Blood Glucose; Body Weight; Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type	1995
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet (London, England), 1998, Sep-12, Volume: 352, Issue:9131 Topics: Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Glyburi	1998
U.K. prospective diabetes study. II. Reduction in HbA1c with basal insulin supplement, sulfonylurea, or biguanide therapy in maturity-onset diabetes. A multicenter study. Diabetes, 1985, Volume: 34, Issue:8 Topics: Adult; Aged; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Gl	1985
Comparison of chlorpropamide and metformin treatment on weight and blood-glucose response of uncontrolled obese diabetics. Lancet (London, England), 1968, Jan-20, Volume: 1, Issue:7534 Topics: Adult; Aged; Blood Glucose; Body Weight; Chlorpropamide; Diabetes Mellitus; Diet Therapy; Female; Hu	1968
Effect of diet, sulphonylureas, and phenformin on peripheral glucose uptake in diabetes and obesity. Lancet (London, England), 1968, Oct-12, Volume: 2, Issue:7572 Topics: Adult; Aged; Blood Flow Velocity; Body Weight; Chlorpropamide; Diabetes Mellitus; Diet Therapy; Fema	1968
Insulin response to glucose in the presence of oral hypoglycemics. Annals of the New York Academy of Sciences, 1968, Mar-26, Volume: 148, Issue:3 Topics: Adolescent; Adult; Biguanides; Chlorpropamide; Diabetes Mellitus; Fatty Acids, Nonesterified; Glucos	1968
Treatment of the obese diabetic. A comparative study of placebo, sulfonylurea and phenformin. Metabolism: clinical and experimental, 1967, Volume: 16, Issue:3 Topics: Blood Glucose; Body Weight; Chlorpropamide; Cholesterol; Clinical Trials as Topic; Diabetes Mellitus	1967
Circadian variation of glucose, insulin, and free fatty acids during long-term use of oral hypoglycaemic agents in diabetes mellitus. British medical journal, 1968, Oct-05, Volume: 4, Issue:5622 Topics: Aged; Blood Glucose; Chlorpropamide; Circadian Rhythm; Diabetes Mellitus; Diet, Diabetic; Fatty Acid	1968

Other Studies

29 other studies available for chlorpropamide and Obesity

Article	Year
Differential regulation of CIDEA and CIDEC expression by insulin via Akt1/2- and JNK2-dependent pathways in human adipocytes. Journal of lipid research, 2011, Volume: 52, Issue:8 Topics: Adipocytes; Apoptosis; Apoptosis Regulatory Proteins; Chlorpropamide; DNA Fragmentation; Down-Regula	2011
THE TREATMENT OF DIABETES WITH ORAL DRUGS AND DIET. Medical times, 1963, Volume: 91 Topics: Chlorpropamide; Diabetes Mellitus; Diet; Diet, Reducing; Obesity; Phenformin; Phenmetrazine; Tolbuta	1963
STUDIES IN GLYCOSURIA AND DIABETES IN NON-WHITE POPULATIONS OF THE TRANSVAAL. I. AFRICANS. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1963, Nov-30, Volume: 37 Topics: Black People; Chlorpropamide; Diabetes Mellitus; Diet; Glycosuria; Health Surveys; Hemochromatosis;	1963
[BIGUANIDES AND SULFONAMIDES IN SMALL DOSES IN THE INITIAL TREATMENT OF THE DIABETES OF THE OBESE PERSON]. Le Diabete, 1963, Volume: 11 Topics: Biguanides; Chlorpropamide; Diabetes Mellitus; Humans; Metformin; Obesity; Sulfanilamide; Sulfanilam	1963
[THE INTRAVENOUS CHLORPROPAMIDE TEST. EARLY AND LATE RESPONSES]. Le Diabete, 1964, Volume: 12 Topics: Acromegaly; Blood Glucose; Chlorpropamide; Cushing Syndrome; Goiter; Graves Disease; Humans; Hypogly	1964
ORAL HYPOGLYCEMIC DRUGS: COMPARATIVE EVALUATION OF TOLBUTAMIDE, CHLORPROPAMIDE AND PHENFORMIN. Medical times, 1964, Volume: 92 Topics: Alkaline Phosphatase; Biomedical Research; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Diabete	1964
EFFECT OF ORAL HYPOGLYCEMIC AGENTS ON SERUM INSULIN-LIKE ACTIVITY OF PATIENTS WITH VARIOUS DEGREES OF CARBOHYDRATE INTOLERANCE. Metabolism: clinical and experimental, 1965, Volume: 14 Topics: Blood; Carbohydrate Metabolism, Inborn Errors; Child; Chlorpropamide; Diabetes Mellitus; Glucose Tol	1965
[2 CASES OF HYPOGLYCEMIA DUE TO CHLORPROPAMIDE IN DIABETIC SUBJECTS]. Bulletins et memoires de la Societe medicale des hopitaux de Paris, 1965, Feb-19, Volume: 116 Topics: Chlorpropamide; Diabetes Mellitus; Drug Therapy; Hypoglycemia; Obesity; Toxicology	1965
AN EVALUATION OF LONG-TERM CHLORPROPAMIDE THERAPY. JAMA, 1965, Sep-06, Volume: 193 Topics: Aged; Chlorpropamide; Diabetes Mellitus; Diet, Diabetic; Drug Therapy; Drug Tolerance; Geriatrics; H	1965
Alterations of plasma opioid activity in human diabetics. Life sciences, 1984, May-21, Volume: 34, Issue:21 Topics: beta-Endorphin; Chlorpropamide; Diabetes Mellitus; Diet, Diabetic; Endorphins; Enkephalin, Leucine;	1984
Recurrent hypoglycemia and obesity in an adolescent--insulinoma or imitator? Clinical pediatrics, 1996, Volume: 35, Issue:3 Topics: Child; Chlorpropamide; Diagnosis, Differential; Female; Humans; Hypoglycemia; Hypoglycemic Agents; I	1996
Type 2 (insulin-independent) diabetes--fibres and flushers. Diabetologia, 1979, Volume: 17, Issue:2 Topics: Chlorpropamide; Diabetes Mellitus; Ethanol; Humans; Obesity; Skin Temperature	1979
Basal normoglycemia attained with chlorpropamide in mild diabetes. Metabolism: clinical and experimental, 1978, Volume: 27, Issue:5 Topics: Blood Glucose; C-Peptide; Capillary Fragility; Chlorpropamide; Circadian Rhythm; Depression, Chemica	1978
Nephrotic syndrome a clinical approach. Hospital practice (Office ed.), 1990, Sep-15, Volume: 25, Issue:9 Topics: Aged; Chlorpropamide; Diabetes Complications; Humans; Male; Naproxen; Nephrotic Syndrome; Obesity; P	1990
Beneficial effect of moderate weight loss in older patients with non-insulin-dependent diabetes mellitus poorly controlled with insulin. Journal of the American Geriatrics Society, 1985, Volume: 33, Issue:2 Topics: Aged; Body Weight; Chlorpropamide; Diabetes Mellitus, Type 2; Diet, Diabetic; Diet, Reducing; Female	1985
Long-range implications for the mother. The Aberdeen experience. Diabetes, 1985, Volume: 34 Suppl 2 Topics: Adolescent; Adult; Autoantibodies; Blood Glucose; Chlorpropamide; Fasting; Female; Follow-Up Studies	1985
Oral management of uncomplicated maturity onset diabetes. The Journal of the Egyptian Medical Association, 1974, Volume: 57, Issue:7-8 Topics: Adult; Aged; Biguanides; Chlorpropamide; Diabetes Mellitus; Diet; Drug Combinations; Glucose Toleran	1974
Diabetes in Kenya. Tropical doctor, 1974, Volume: 4, Issue:4 Topics: Adult; Age Factors; Blood Glucose; Chlorpropamide; Diabetes Complications; Diabetes Mellitus; Diabet	1974
Oral therapy in diabetes. Journal of the Royal College of Physicians of London, 1972, Volume: 7, Issue:1 Topics: Acetohexamide; Administration, Oral; Animals; Chlorpropamide; Diabetes Mellitus; Diet Therapy; Evalu	1972
The pattern of rsponse of plasma insulin and glucose to meals and fasting during chlorpropamide therapy. Annals of internal medicine, 1968, Volume: 68, Issue:4 Topics: Adult; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Fasting; Fatty Acids, Nonesterified; Female	1968
Treatment with chlorpropamide-phenformin combination in adult, obese, ketosis-resistant diabetics. Israel journal of medical sciences, 1971, Volume: 7, Issue:6 Topics: Age Factors; Aged; Chlorpropamide; Diabetes Complications; Diabetes Mellitus; Diabetic Ketoacidosis;	1971
Assessment of the need for continued oral therapy in diabetics. British medical journal, 1972, Mar-11, Volume: 1, Issue:5801 Topics: Administration, Oral; Adult; Aged; Blood Glucose; Body Weight; Chlorpropamide; Diabetes Mellitus; Fe	1972
Continued oral therapy in diabetes. British medical journal, 1972, Apr-08, Volume: 2, Issue:5805 Topics: Administration, Oral; Aged; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Diet Therapy; Humans;	1972
[Round-table discussion on the value of the association of chlorpropamide with metformin in the treatment of diabetes mellitus]. Journal de medecine de Lyon, 1972, Feb-05, Volume: 53, Issue:222 Topics: Aged; Chlorpropamide; Diabetes Mellitus; Dosage Forms; Drug Combinations; Humans; Metformin; Obesity	1972
Restoration of normal drinking behavior by chlorpropamide in patients with hypodipsia and diabetes insipidus. The American journal of medicine, 1971, Volume: 51, Issue:3 Topics: Brain Neoplasms; Child; Chlorpropamide; Craniopharyngioma; Cysts; Dehydration; Diabetes Insipidus; D	1971
The place of phenformin in the treatment of diabetes. Postgraduate medical journal, 1969, Volume: 45 Topics: Adult; Capsules; Chlorpropamide; Diabetes Mellitus; Humans; Insulin; Middle Aged; Obesity; Phenformi	1969
[Diabetes mellitus. XII. Oral diabetes therapy]. Zeitschrift fur arztliche Fortbildung, 1971, Feb-01, Volume: 65, Issue:3 Topics: Administration, Oral; Biguanides; Carbutamide; Chlorpropamide; Diabetes Mellitus; Humans; Hypoglycem	1971
Combinations of oral hypoglycemic drugs in obese, insulin-resistant diabetics. Geriatrics, 1968, Volume: 23, Issue:9 Topics: Adult; Aged; Blood Glucose; Carbohydrate Metabolism; Chlorpropamide; Diabetes Mellitus; Drug Synergi	1968
Clinical evaluation of the effect of glyclopyramide in diabetes mellitus. The Tohoku journal of experimental medicine, 1969, Volume: 98, Issue:2 Topics: Adult; Age Factors; Aged; Animals; Blood Glucose; Carbohydrates; Chlorpropamide; Cholesterol; Diabet	1969