chlorpropamide has been researched along with Diabetes Mellitus, Type 1 in 36 studies
Chlorpropamide: A sulfonylurea hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. (From Martindale, The Extra Pharmacopoeia, 30th ed, p277)
chlorpropamide : An N-sulfonylurea that is urea in which a hydrogen attached to one of the nitrogens is substituted by 4-chlorobenzenesulfonyl group and a hydrogen attached to the other nitrogen is substituted by propyl group. Chlorpropamide is a hypoglycaemic agent used in the treatment of type 2 (non-insulin-dependent) diabetes mellitus not responding to dietary modification.
Diabetes Mellitus, Type 1: A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An epidemiological study was carried out to compare the prevalence of facial flushing in non-diabetics, patients with insulin dependent diabetes, and patients with non-insulin dependent diabetes in response to 40 ml sherry taken 12 hours after 250 mg chlorpropamide or placebo, administered double blind in randomised order." | 9.05 | Epidemiological study of prevalence of chlorpropamide alcohol flushing in insulin dependent diabetics, non-insulin dependent diabetics, and non-diabetics. ( Jarrett, RJ; Keen, H; Marsden, P; Murrells, T; Ng Tang Fui, S; Stott, R; Strakosch, C, 1983) |
| "An epidemiological study was carried out to compare the prevalence of facial flushing in non-diabetics, patients with insulin dependent diabetes, and patients with non-insulin dependent diabetes in response to 40 ml sherry taken 12 hours after 250 mg chlorpropamide or placebo, administered double blind in randomised order." | 5.05 | Epidemiological study of prevalence of chlorpropamide alcohol flushing in insulin dependent diabetics, non-insulin dependent diabetics, and non-diabetics. ( Jarrett, RJ; Keen, H; Marsden, P; Murrells, T; Ng Tang Fui, S; Stott, R; Strakosch, C, 1983) |
| "After the observation of decreasing insulin resistance in a diabetic patient during treatment with mebendazole for nematosis, we investigated the effect of mebendazole on metabolic control in six Type 1 (insulin-dependent) and six Type 2 (non-insulin-dependent) diabetic patients, eight of whom were chronically resistant to conventional treatment." | 3.67 | Improvement of metabolic control in diabetic patients during mebendazole administration: preliminary studies. ( Boden, G; Caprio, S; Dayal, VK; Hoeldtke, RD; Mozzoli, MA; Owen, OE; Ray, TK; Reichard, GA; Shuman, CR; Smith, RH, 1984) |
| "Among 53 patients with noninsulin-dependent diabetes (NIDD), chlorpropamide alcohol flushing (CPAF) was more prevalent than among 18 patients with insulin-dependent diabetes (64 vs." | 3.67 | Prevalence of chlorpropamide alcohol flush in Jewish Israeli diabetics. The role of serum chlorpropamide concentrations. ( Almog, S; Berezin, M; Brazu-Albu, J; Segal, P, 1985) |
| "Chlorpropamide was found to have a generalized cholesterol lowering effect (progressive significant fall in mean total cholesterol, LDL-C, HDL-C, and HDL3-C) with no significant change in the ratio of high-density lipoprotein to low-density lipoprotein cholesterol which was independent of insulin secretion." | 1.27 | Chlorpropamide lowers serum and lipoprotein cholesterol in insulin-dependent diabetes. ( Elkeles, RS; Richmond, W; Seviour, PW; Teal, TK, 1986) |
| "In comparison to NIDDM of maturity onset (40/8), IDDM (40/6) and healthy controls (40/2) the frequency of positive CPAF showed no significant differences." | 1.26 | [Chlorpropamide-alcohol flush test in non-insulin-dependent diabetes mellitus in young age (MODY type)]. ( Adolph, W; Panzram, G, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 35 (97.22) | 18.7374 |
| 1990's | 1 (2.78) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| FIORIO, C | 1 |
| CASTELLAZZI, R | 1 |
| MOSS, JM | 1 |
| DELAWTER, DE | 1 |
| GALLAGHER, EJ | 1 |
| KEEN, H | 4 |
| Mutch, WJ | 1 |
| Stowers, JM | 1 |
| Jarrett, RJ | 2 |
| Guillausseau, PJ | 2 |
| Akoka, C | 2 |
| Lubetzki, J | 2 |
| Caprio, S | 1 |
| Ray, TK | 1 |
| Boden, G | 1 |
| Reichard, GA | 1 |
| Shuman, CR | 1 |
| Smith, RH | 1 |
| Mozzoli, MA | 1 |
| Dayal, VK | 1 |
| Hoeldtke, RD | 1 |
| Owen, OE | 1 |
| Rogoziński, R | 1 |
| Patewicz, K | 1 |
| Torzecki, Z | 1 |
| Jurga-Waniek, K | 1 |
| Mroszczyk, M | 1 |
| Błaszczyk, M | 1 |
| Pontiroli, AE | 1 |
| Alberetto, M | 1 |
| Bertoletti, A | 1 |
| Baio, G | 1 |
| Pozza, G | 1 |
| Ng Tang Fui, S | 1 |
| Strakosch, C | 1 |
| Murrells, T | 1 |
| Marsden, P | 2 |
| Stott, R | 1 |
| Babadzhanova, GIu | 1 |
| Mazovetskiĭ, AG | 1 |
| Kuraeva, TL | 1 |
| Mukhamedov, KhA | 1 |
| Groop, L | 1 |
| Eriksson, CJ | 1 |
| Wåhlin-Boll, E | 1 |
| Melander, A | 1 |
| MacDonald, MJ | 1 |
| Fui, SN | 1 |
| Jarrett, J | 1 |
| Gossain, V | 1 |
| Panzram, G | 1 |
| Adolph, W | 1 |
| Dreyer, M | 1 |
| Kühnau, J | 1 |
| Rüdiger, HW | 1 |
| Fajans, SS | 1 |
| Cloutier, MC | 1 |
| Crowther, RL | 1 |
| Shen, SW | 1 |
| Bressler, R | 1 |
| Teuscher, A | 1 |
| Radder, JK | 1 |
| Gill, G | 1 |
| Seviour, PW | 1 |
| Teal, TK | 1 |
| Richmond, W | 1 |
| Elkeles, RS | 1 |
| Moore, DC | 1 |
| Stanisstreet, M | 1 |
| Clarke, CA | 1 |
| Beck, F | 1 |
| Hipkin, LJ | 1 |
| Bońkowska, M | 1 |
| Sroczyński, J | 1 |
| Szramek-Urbaniak, A | 1 |
| Jerntorp, P | 1 |
| Ohlin, H | 1 |
| Sundkvist, G | 1 |
| Almér, LO | 1 |
| Sabán, J | 1 |
| Ordóñez, A | 1 |
| Navascués, I | 1 |
| Suárez Terry, R | 1 |
| Serrano Ríos, M | 1 |
| Dempe, A | 1 |
| Jordan, A | 1 |
| Segal, P | 1 |
| Brazu-Albu, J | 1 |
| Almog, S | 1 |
| Berezin, M | 1 |
| Ser, I | 1 |
| Tattersall, RB | 1 |
| Dacou-Voutetakis, C | 1 |
| Constantinidis, M | 1 |
| Moschos, A | 1 |
| Vlachou, C | 1 |
| Matsaniotis, N | 1 |
| Bretz, GW | 1 |
| Baghdassarian, A | 1 |
| Graber, JD | 1 |
| Zacherle, BJ | 1 |
| Norum, RA | 1 |
| Blizzard, RM | 1 |
| Crawford, JD | 1 |
| Bode, HH | 1 |
| Naccarato, R | 1 |
| Broglio, G | 1 |
| Sirigu, F | 1 |
| Previato, G | 1 |
| Fameli, O | 1 |
4 reviews available for chlorpropamide and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Clinical and etiological heterogeneity of idiopathic diabetes mellitus. The banting memorial lecture.
Topics: Adenoma, Islet Cell; Adult; Antibodies, Viral; Autoantibodies; Cell Adhesion; Chlorpropamide; Chromo | 1979 |
Clinical pharmacology of oral antidiabetic agents (second of two parts).
Topics: Administration, Oral; Cardiovascular Diseases; Chlorpropamide; Clinical Trials as Topic; Diabetes Me | 1977 |
Practical management of diabetes in the tropics.
Topics: Blood Glucose; Chlorpropamide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucose | 1990 |
[Flush induced by chlorpropamide-alcohol (CAF): a genetic marker of diabetes mellitus or an undesirable effect of the drug?].
Topics: Acetaldehyde; Alcohol Drinking; Chlorpropamide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2 | 1985 |
3 trials available for chlorpropamide and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Epidemiological study of prevalence of chlorpropamide alcohol flushing in insulin dependent diabetics, non-insulin dependent diabetics, and non-diabetics.
Topics: Adult; Aged; Alcoholic Beverages; Chlorpropamide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type | 1983 |
Test for chlorpropamide-alcohol flush becomes positive after prolonged chlorpropamide treatment in insulin-dependent and non-insulin-dependent diabetics.
Topics: Alcoholic Beverages; Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diagnosis, Differ | 1983 |
Clinical pharmacology of oral antidiabetic agents (second of two parts).
Topics: Administration, Oral; Cardiovascular Diseases; Chlorpropamide; Clinical Trials as Topic; Diabetes Me | 1977 |
30 other studies available for chlorpropamide and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
[CLINICAL EVALUATION OF AN ORAL ANTIDIABETIC CONSISTING OF THE ASSOCIATION OF A SULFONYLUREA AND A BIGUANIDE].
Topics: Adolescent; Biguanides; Child; Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Geriatr | 1964 |
ORAL HYPOGLYCEMIC DRUGS: COMPARATIVE EVALUATION OF TOLBUTAMIDE, CHLORPROPAMIDE AND PHENFORMIN.
Topics: Alkaline Phosphatase; Biomedical Research; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Diabete | 1964 |
THE FAMILY DOCTOR AND THE DIABETIC.
Topics: Acidosis; Adolescent; Child; Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetic | 1965 |
Reversible mild diabetes in children after treatment with chlorpropamide.
Topics: Administration, Oral; Adolescent; Child; Child, Preschool; Chlorpropamide; Diabetes Mellitus, Type 1 | 1980 |
Reversal of "mild" diabetes by chlorpropamide.
Topics: Child; Chlorpropamide; Diabetes Mellitus, Type 1; Humans | 1980 |
[The alcohol-chlorpropamide test. Study and diagnostic value of changes in cutaneous temperature].
Topics: Chlorpropamide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Ethanol; Face; Flushing; Human | 1984 |
Improvement of metabolic control in diabetic patients during mebendazole administration: preliminary studies.
Topics: Adult; Benzimidazoles; Blood Glucose; C-Peptide; Chlorpropamide; Diabetes Mellitus, Type 1; Diabetes | 1984 |
[Karyometric study of hepatocytes in diabetic patients treated with insulin or chlorpropamide].
Topics: Cell Nucleus; Chlorpropamide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Humans; Insulin; | 1984 |
Sulfonylureas enhance in vivo the effectiveness of insulin in type 1 (insulin dependent) diabetes mellitus.
Topics: Adolescent; Adult; Chlorpropamide; Diabetes Mellitus, Type 1; Drug Interactions; Female; Glipizide; | 1984 |
[The chlorpropamide-alcohol test in diabetes mellitus].
Topics: Adult; Chlorpropamide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagnosis, Differential | 1984 |
Chlorpropamide-alcohol flush: significance of body weight, sex and serum chlorpropamide level.
Topics: Body Weight; Chlorpropamide; Diabetes Mellitus, Type 1; Drug Interactions; Ethanol; Female; Flushing | 1984 |
[Facial vasomotor flushing due to alcohol-chlorpropamide. Prevalence in diabetic and non-diabetic patients].
Topics: Adult; Aged; Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2 | 1984 |
Etiology and classification of diabetes in children. Practical genetics and prognosis counseling.
Topics: Adolescent; Adult; Animals; Child; Child, Preschool; Chlorpropamide; Diabetes Mellitus, Type 1; Diab | 1983 |
[Chlorpropamide-alcohol flush test in non-insulin-dependent diabetes mellitus in young age (MODY type)].
Topics: Adolescent; Adult; Aged; Child; Chlorpropamide; Diabetes Mellitus, Type 1; Ethanol; Female; Humans; | 1982 |
Chlorpropamide-alcohol flushing is not useful for individual genetic counseling of diabetic patients.
Topics: Adolescent; Adult; Blushing; C-Peptide; Child; Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, | 1980 |
[The biological effect of purely synthetic human insulin in patients with diabetes mellitus].
Topics: Adult; Aged; Buformin; Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; Hormone | 1979 |
[Diabetes mellitus and heredity].
Topics: Adult; Child; Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Ethanol; HLA Antigens; H | 1979 |
Chlorpropamide lowers serum and lipoprotein cholesterol in insulin-dependent diabetes.
Topics: Adult; Blood Glucose; Chlorpropamide; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mell | 1986 |
Effect on rat embryos of in vitro culture in sera from human diabetic patients.
Topics: Animals; Chlorpropamide; Culture Media; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Embryo | 1987 |
[Value of the chlorpropamide-alcohol test for determining the type of diabetes mellitus].
Topics: Adolescent; Adult; Aged; Chlorpropamide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagn | 1987 |
[Studies of the functional state of blood vessels in various types of diabetes mellitus using the chlorpropamide-alcohol test].
Topics: Adult; Aged; Chlorpropamide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Ethanol; Humans; | 1986 |
Effects of chlorpropamide and alcohol on aldehyde dehydrogenase activity and blood acetaldehyde concentration.
Topics: Acetaldehyde; Adult; Aged; Aldehyde Dehydrogenase; Chlorpropamide; Diabetes Mellitus, Type 1; Diabet | 1986 |
[Frequency of a positive result in the chlorpropamide-alcohol flush test in type I and type II diabetes].
Topics: Adolescent; Adult; Aged; Chlorpropamide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagn | 1986 |
Prevalence of chlorpropamide alcohol flush in Jewish Israeli diabetics. The role of serum chlorpropamide concentrations.
Topics: Adult; Aged; Alcohol Drinking; Body Temperature; Chlorpropamide; Diabetes Mellitus, Type 1; Diabetes | 1985 |
Plasma-insulin in a young diabetic after 13 years' oral therapy.
Topics: Administration, Oral; Adolescent; Child; Chlorpropamide; Diabetes Mellitus, Type 1; Humans; Insulin; | 1971 |
Mild familial diabetes with dominant inheritance.
Topics: Acetohexamide; Adolescent; Adult; Aged; Blood Glucose; Carbohydrates; Child; Chlorpropamide; Diabete | 1974 |
Diabetes mellitus following mumps. Insulin reserve.
Topics: Blood Glucose; Child; Child, Preschool; Chlorpropamide; Diabetes Mellitus, Type 1; Female; Glucose; | 1974 |
Coexistence of diabetes mellitus and insipidus and optic atrophy in two male siblings. Studies and review of literature.
Topics: Adolescent; Chlorpropamide; Diabetes Insipidus; Diabetes Mellitus, Type 1; Genes, Recessive; Humans; | 1970 |
Diabetes and the amplifier hypothesis.
Topics: Child; Chlorpropamide; Diabetes Insipidus; Diabetes Mellitus; Diabetes Mellitus, Type 1; Humans; Ins | 1970 |
[Some advantages of the combination of phenformin and chlorpropamide in the therapy of diabetes mellitus].
Topics: Adolescent; Adult; Aged; Child; Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female | 1965 |