chlorpropamide has been researched along with Complications of Diabetes Mellitus in 49 studies
Chlorpropamide: A sulfonylurea hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. (From Martindale, The Extra Pharmacopoeia, 30th ed, p277)
chlorpropamide : An N-sulfonylurea that is urea in which a hydrogen attached to one of the nitrogens is substituted by 4-chlorobenzenesulfonyl group and a hydrogen attached to the other nitrogen is substituted by propyl group. Chlorpropamide is a hypoglycaemic agent used in the treatment of type 2 (non-insulin-dependent) diabetes mellitus not responding to dietary modification.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chlorpropamide (CPM) has been reported to produce impaired water excretion due to the enhancement of renal vasopressin (ADH) action and/or due to centrally enhanced ADH release, but it is still unknown whether CPM gives rise to ADH release with a subsequent hyponatremia in diabetes mellitus (DM), which, in turn, causes an impairment of the central nervous system." | 7.69 | Chlorpropamide-induced ADH release, hyponatremia and central pontine myelinolysis in diabetes mellitus. ( Funyu, T; Kimura, T; Mori, T; Ohta, M; Ota, K; Sahata, T; Sato, K; Shoji, M; Sugimura, K; Yamamoto, T, 1995) |
| "A patient with severe idiopathic diabetes insipidus, complicated by diabetes mellitus, was first treated with a combination o clofibrate and chlorpropamide." | 7.66 | Treatment of diabetes insipidus complicated by diabetes mellitus with chlorpropamide and clofibrate. ( Manns, M; Meyer zum Büschenfelde, KH; Schneider, J, 1980) |
| "Ten patients with primary hyperparathyroidism were placed on a constant 30 mEq of calcium and 120 meq of sodium diet, and alterations in their calcium balance in response to standard oral doses of chlorpropamide were studied over a 4 day control period and a 4 day treatment period." | 7.66 | Chlorpropamide-induced changes in patients with hyperparathyroidism. ( Breslau, N; Moses, AM; Numann, PJ, 1979) |
| "Chlorpropamide (CPM) has been reported to produce impaired water excretion due to the enhancement of renal vasopressin (ADH) action and/or due to centrally enhanced ADH release, but it is still unknown whether CPM gives rise to ADH release with a subsequent hyponatremia in diabetes mellitus (DM), which, in turn, causes an impairment of the central nervous system." | 3.69 | Chlorpropamide-induced ADH release, hyponatremia and central pontine myelinolysis in diabetes mellitus. ( Funyu, T; Kimura, T; Mori, T; Ohta, M; Ota, K; Sahata, T; Sato, K; Shoji, M; Sugimura, K; Yamamoto, T, 1995) |
| "A patient with severe idiopathic diabetes insipidus, complicated by diabetes mellitus, was first treated with a combination o clofibrate and chlorpropamide." | 3.66 | Treatment of diabetes insipidus complicated by diabetes mellitus with chlorpropamide and clofibrate. ( Manns, M; Meyer zum Büschenfelde, KH; Schneider, J, 1980) |
| "Ten patients with primary hyperparathyroidism were placed on a constant 30 mEq of calcium and 120 meq of sodium diet, and alterations in their calcium balance in response to standard oral doses of chlorpropamide were studied over a 4 day control period and a 4 day treatment period." | 3.66 | Chlorpropamide-induced changes in patients with hyperparathyroidism. ( Breslau, N; Moses, AM; Numann, PJ, 1979) |
| "A 72-year-old male being treated with chlorpropamide for diabetes mellitus had an emergency operation for a perforated gastric ulcer." | 3.65 | Postoperative hypoglycaemic coma associated with chlorpropamide. ( Khazzam, AS; Schen, RJ, 1975) |
| "In view of the increasing incidence of primary hepatocellular carcinoma in western Europe and concern that this may in part be related to long-term use of drugs which cause hepatic microsomal enzyme induction, we undertook a comparison of long-term drug use in 105 patients with hepatocellular carcinoma and equal numbers of age and sex-matched patients with colorectal tumours and with fractures of femur." | 1.27 | Diabetes mellitus and primary hepatocellular carcinoma. ( Clarke, J; Gray, JM; Lawson, DH; Lee, FD; McKillop, C; Patrick, RS, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 46 (93.88) | 18.7374 |
| 1990's | 2 (4.08) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (2.04) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kaomongkolgit, R | 1 |
| Copperman, IJ | 1 |
| Cantwell, AR | 1 |
| Martz, W | 1 |
| Fisher, AA | 1 |
| Laakso, M | 1 |
| Nuorva, K | 1 |
| Aro, A | 1 |
| Uusitupa, M | 1 |
| Siitonen, O | 1 |
| Huupponen, R | 1 |
| Tattersall, RB | 1 |
| Ohlin, H | 1 |
| Jerntorp, P | 1 |
| Bergström, B | 1 |
| Almér, LO | 1 |
| Valkusz, Z | 1 |
| Laczi, F | 1 |
| László, FA | 3 |
| Tsou, JY | 1 |
| Kotler, M | 1 |
| Lavine, RL | 1 |
| Barnett, AH | 1 |
| Pyke, DA | 3 |
| Aasen, G | 1 |
| Frey, HM | 2 |
| Manns, M | 1 |
| Schneider, J | 1 |
| Meyer zum Büschenfelde, KH | 1 |
| Kimura, T | 1 |
| Ota, K | 1 |
| Shoji, M | 1 |
| Funyu, T | 1 |
| Ohta, M | 1 |
| Sato, K | 1 |
| Yamamoto, T | 1 |
| Mori, T | 1 |
| Sahata, T | 1 |
| Sugimura, K | 1 |
| Numann, PJ | 1 |
| Breslau, N | 1 |
| Moses, AM | 1 |
| Leslie, RD | 2 |
| Soler, NG | 1 |
| Bennett, MA | 1 |
| Pentecost, BL | 1 |
| Fitzgerald, MG | 1 |
| Malins, JM | 1 |
| Schen, RJ | 1 |
| Khazzam, AS | 1 |
| Czakó, L | 3 |
| Kahán-László, I | 1 |
| Bernard, DB | 1 |
| Lawson, DH | 1 |
| Gray, JM | 1 |
| McKillop, C | 1 |
| Clarke, J | 1 |
| Lee, FD | 1 |
| Patrick, RS | 1 |
| True, BL | 1 |
| Perry, PJ | 1 |
| Burns, EA | 1 |
| Bogie, W | 1 |
| Peers, M | 1 |
| Fähndrich, W | 1 |
| Liebermeister, H | 1 |
| Schmitt, H | 1 |
| Daweke, H | 1 |
| Stowers, JM | 1 |
| Steel, JM | 1 |
| Mngola, EN | 1 |
| Besser, GM | 1 |
| Mortimer, CH | 1 |
| McNeilly, AS | 1 |
| Thorner, MO | 1 |
| Batistoni, GA | 1 |
| Bloom, SR | 1 |
| Kastrup, KW | 1 |
| Hanssen, KF | 1 |
| Hall, R | 1 |
| Coy, DH | 1 |
| Kastin, AJ | 1 |
| Schally, AV | 1 |
| Henning, H | 1 |
| Look, D | 1 |
| Adadevoh, BK | 1 |
| Menakaya, GC | 1 |
| Francis, TI | 1 |
| Adi, FC | 1 |
| Schneider, T | 1 |
| Lopis, S | 1 |
| Kadota, I | 1 |
| Kovács, K | 2 |
| Szám, I | 2 |
| Radó, JP | 1 |
| Borbély, L | 2 |
| Szigeti, L | 2 |
| Takó, J | 2 |
| Haim, S | 1 |
| Friedman-Birnbaum, R | 1 |
| Shafrir, A | 1 |
| Bricker, LA | 1 |
| Mintz, DH | 1 |
| Lev-Ran, AS | 1 |
| Pettipierre, B | 1 |
| Fabre, J | 2 |
| Pabst, R | 1 |
| Huchzermeyer, H | 1 |
| Kalden, J | 1 |
| Wajchenberg, BL | 1 |
| Modesto Filho, J | 1 |
| Ventrella, C | 1 |
| Giannini, SD | 1 |
| Liberman, B | 1 |
| Hoxter, G | 1 |
| Rudhardt, M | 1 |
| Petitpierre, B | 1 |
| Perrin, L | 1 |
| Devrim, S | 1 |
| Radó, J | 1 |
| Hagen, GA | 1 |
| Frawley, TF | 1 |
| Goto, A | 1 |
| Nagase, M | 1 |
| Ogawa, N | 1 |
| Yozai, S | 1 |
| Kawanishi, K | 1 |
| Rosenlund, B | 1 |
| Duncan, GG | 1 |
| Elliott, FA | 1 |
| Duncan, TG | 1 |
| Schatanoff, J | 1 |
| László, F | 1 |
| Micarelli, A | 1 |
| Martinelli, GP | 1 |
5 reviews available for chlorpropamide and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
[25 years of diabetic treatment by oral hypoglycemic agents: successes and failures].
Topics: Aged; Aging; Blood Glucose; Cardiovascular Diseases; Chlorpropamide; Diabetes Complications; Diabete | 1984 |
Oral treatment in diabetes.
Topics: Acetohexamide; Acidosis; Administration, Oral; Animals; Biguanides; Cardiovascular Diseases; Chlorpr | 1972 |
[Evaluation of therapy of diabetes mellitus, with special reference to the control of diabetes mellitus with oral antidiabetics].
Topics: Adult; Animals; Blood Glucose; Cattle; Chlorpropamide; Diabetes Complications; Diabetes Mellitus; Di | 1969 |
Generalized granuloma annulare: relationship to diabetes mellitus as revealed in 8 cases.
Topics: Adult; Chlorpropamide; Diabetes Complications; Diabetes Mellitus; Diet, Diabetic; Female; Granuloma; | 1970 |
Insulin-independent diabetes mellitus.
Topics: Acetohexamide; Adult; Age Factors; Aged; Basement Membrane; Capillaries; Carbohydrate Metabolism, In | 1971 |
4 trials available for chlorpropamide and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
Chlorpropamide-alcohol flushing, aldehyde dehydrogenase activity, and diabetic complications.
Topics: Acetaldehyde; Aged; Aldehyde Oxidoreductases; Chlorpropamide; Diabetes Complications; Diabetes Melli | 1982 |
HB419 (glibenclamide) in the treatment of diabetes mellitus.
Topics: Adult; Age Factors; Aged; Biguanides; Chlorpropamide; Clinical Trials as Topic; Diabetes Complicatio | 1969 |
[Concurrence of diabetes insipidus and diabetes mellitus. Treatment with chlorpropamide].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Blood Glucose; Chlorpropamide; Clinical Trials as | 1969 |
Clinico-pharmacological investigations with chlorpropamide in diabetes insipidus associated with diabetes mellitus.
Topics: Carbutamide; Chlorpropamide; Clinical Trials as Topic; Clopamide; Craniocerebral Trauma; Diabetes Co | 1970 |
40 other studies available for chlorpropamide and Complications of Diabetes Mellitus
| Article | Year |
|---|---|
Oral lichenoid drug reaction associated with antihypertensive and hypoglycemic drugs.
Topics: Antihypertensive Agents; Atenolol; Chlorpropamide; Diabetes Complications; Diabetes Mellitus; Erythe | 2010 |
Purpura in a patient taking chlordiazepoxid.
Topics: Aged; Chlordiazepoxide; Chlorpropamide; Diabetes Complications; Female; Humans; Insulin, Long-Acting | 1967 |
Idiopathic bullae in diabetics. Bullosis diabeticorum.
Topics: Adult; Aged; Biopsy; Blister; Chlorpropamide; Diabetes Complications; Diabetic Neuropathies; Diet Th | 1967 |
Systemic contact dermatitis from Orinase and Diabinese in diabetics with para-amino hypersensitivity.
Topics: Adult; Benzocaine; Chlorpropamide; Diabetes Complications; Drug Eruptions; Female; Humans; Male; Mid | 1982 |
Chlorpropamide-alcohol flushing and coronary heart disease in non-insulin dependent diabetics.
Topics: Adult; Chlorpropamide; Coronary Disease; Diabetes Complications; Diabetic Angiopathies; Ethanol; Fac | 1983 |
Development of the Schwartz-Bartter syndrome after the administration of chlorpropamide and 1-deamino-8-D-arginine vasopressin.
Topics: Arginine Vasopressin; Body Water; Chlorpropamide; Deamino Arginine Vasopressin; Diabetes Complicatio | 1982 |
Thyroid-blocking activity of chlorpropamide in a diabetic patient with hyperthyroidism.
Topics: Chlorpropamide; Depression, Chemical; Diabetes Complications; Diabetes Mellitus; Female; Humans; Hyp | 1981 |
Chlorpropamide-alcohol flushing and large-vessel disease in non-insulin-dependent diabetes.
Topics: Cardiovascular Diseases; Chlorpropamide; Diabetes Complications; Erythema; Ethanol; Humans; Middle A | 1980 |
Excessive sensitivity to the hyponatremic effect of chlorpropamide in a patient with diabetes mellitus and anterior pituitary insufficiency.
Topics: Aged; Chlorpropamide; Diabetes Complications; Diabetes Mellitus; Female; Humans; Hyponatremia; Osmol | 1980 |
Treatment of diabetes insipidus complicated by diabetes mellitus with chlorpropamide and clofibrate.
Topics: Adult; Chlorpropamide; Clofibrate; Diabetes Complications; Diabetes Insipidus; Drug Therapy, Combina | 1980 |
Chlorpropamide-induced ADH release, hyponatremia and central pontine myelinolysis in diabetes mellitus.
Topics: Aged; Chlorpropamide; Demyelinating Diseases; Diabetes Complications; Diabetes Mellitus; Female; Hum | 1995 |
Chlorpropamide-induced changes in patients with hyperparathyroidism.
Topics: Adenosine Monophosphate; Adult; Aged; Calcium; Chlorpropamide; Diabetes Complications; Female; Human | 1979 |
Chlorpropamide-alcohol flushing: a dominantly inherited trait associated with diabetes.
Topics: Adolescent; Adult; Aged; Alcoholic Beverages; Blushing; Child; Chlorpropamide; Diabetes Complication | 1978 |
Chlorpropamide-alcohol flushing: a definition of its relation to non-insulin-dependent diabetes.
Topics: Adolescent; Adult; Aged; Alcoholic Beverages; Blushing; Child; Chlorpropamide; Diabetes Complication | 1978 |
Myocardial infarction in diabetics.
Topics: Administration, Oral; Adult; Aged; Chlorpropamide; Coronary Care Units; Diabetes Complications; Diab | 1975 |
Postoperative hypoglycaemic coma associated with chlorpropamide.
Topics: Aged; Chlorpropamide; Diabetes Complications; Diabetes Mellitus; Diabetic Coma; Humans; Hypoglycemia | 1975 |
[Combined clofibrate-chlorpropamide therapy in diabetes insipidus complicated with diabetes mellitus].
Topics: Chlorpropamide; Clofibrate; Diabetes Complications; Diabetes Insipidus; Diuresis; Drug Therapy, Comb | 1975 |
Nephrotic syndrome a clinical approach.
Topics: Aged; Chlorpropamide; Diabetes Complications; Humans; Male; Naproxen; Nephrotic Syndrome; Obesity; P | 1990 |
Diabetes mellitus and primary hepatocellular carcinoma.
Topics: Adult; Carcinoma, Hepatocellular; Chlorpropamide; Diabetes Complications; Diabetes Mellitus; Female; | 1986 |
Profound hypoglycemia with the addition of a tricyclic antidepressant to maintenance sulfonylurea therapy.
Topics: Aged; Chlorpropamide; Depressive Disorder; Diabetes Complications; Diabetes Mellitus; Doxepin; Drug | 1987 |
Letter: Antidiabetic treatment and myocardial infarction.
Topics: Chlorpropamide; Diabetes Complications; Diabetes Mellitus; Humans; Myocardial Infarction; Ventricula | 1974 |
[A comparison of intravenous tolbutamide and insulin administration during and after operation in patients with maturity-onset diabetes (author's transl)].
Topics: Administration, Oral; Age Factors; Aged; Anesthesia, General; Blood Glucose; Carbohydrates; Carbutam | 1974 |
Diabetes in Kenya.
Topics: Adult; Age Factors; Blood Glucose; Chlorpropamide; Diabetes Complications; Diabetes Mellitus; Diabet | 1974 |
Long-term infusion of growth hormone release inhibiting hormone in acromegaly: effects on pituitary and pancreatic hormones.
Topics: Acromegaly; Adrenocorticotropic Hormone; Aged; Blood Glucose; Chlorpropamide; Diabetes Complications | 1974 |
[Reaction of diabetic carbohydrate metabolism on the change from chlorpropamide to glibenclamide].
Topics: Adult; Chlorpropamide; Diabetes Complications; Diabetes Mellitus; Female; Glyburide; Humans; Hypogly | 1972 |
Absence of hyponatraemia in African diabetics on chlorpropamide.
Topics: Adolescent; Adult; Aged; Bicarbonates; Chlorides; Chlorpropamide; Diabetes Complications; Diabetes M | 1973 |
Diabetes mellitus associated with epidemic of infectious hepatitis in Nigeria.
Topics: Adult; Chlorpropamide; Diabetes Complications; Diabetes Mellitus; Glucose Tolerance Test; Hepatitis | 1974 |
Treatment with chlorpropamide-phenformin combination in adult, obese, ketosis-resistant diabetics.
Topics: Age Factors; Aged; Chlorpropamide; Diabetes Complications; Diabetes Mellitus; Diabetic Ketoacidosis; | 1971 |
[The effect of renal insufficiency on the hypoglycemic action of sulfonylureas. Kinetics of chlorpropamide in a case of nephropathy].
Topics: Adult; Aged; Chlorpropamide; Diabetes Complications; Diabetes Mellitus; Female; Glomerular Filtratio | 1972 |
[Chlorpropamide therapy of diabetes insipidus].
Topics: Chlorpropamide; Diabetes Complications; Diabetes Insipidus; Diuresis; Humans; Male; Middle Aged; Vas | 1972 |
Lipoatrophic diabetes: a new variant characterized by tapeto-retinal degeneration, late onset generalized lipoatrophy, insulin-resistant hyperglycemia and hyperlipidemia.
Topics: Adipose Tissue; Adolescent; Adult; Age Factors; Blood Glucose; Chlorpropamide; Cholesterol; Depressi | 1972 |
[Kinetics of chlorpropamide in renal insufficiency. Effect of associated therapeutics].
Topics: Chloramphenicol; Chlorpropamide; Diabetes Complications; Diabetes Mellitus; Drug Interactions; Human | 1971 |
[Recent acquisitions on insulin homeostasis (apropos of a case of diabetes mellitus complicated by cholostatic hepatitis)].
Topics: Adult; Chlorpropamide; Cholestasis; Diabetes Complications; Homeostasis; Humans; Insulin; Male | 1969 |
[Clinical and pharmacologic studies in diabetes insipidus complicated by diabetes mellitus].
Topics: Chlorpropamide; Diabetes Complications; Diabetes Insipidus; Diuresis; Furosemide; Humans; Male; Midd | 1970 |
Hyponatremia due to sulfonylurea compounds.
Topics: Aged; Atrophy; Blood; Brain Diseases; Chlorpropamide; Diabetes Complications; Diabetes Mellitus; Fem | 1970 |
[Diabetes insipidus with diabetes mellitus--changes of serum I.R.I. and effect of oral antidiabetics].
Topics: Adult; Chlorpropamide; Diabetes Complications; Diabetes Insipidus; Diabetes Mellitus; Humans; Insuli | 1970 |
Studies in patients with chlorpropamide-induced hypoglycemia.
Topics: Aged; Blood Glucose; Chlorpropamide; Diabetes Complications; Female; Glucose; Humans; Hypoglycemia; | 1970 |
Some clinical potentials of chlorophenoxyisobutyrate (clofibrate) therapy (hyperlipidemia--angina pectoris--blood sludging-diabetic neuropathy).
Topics: Acetohexamide; Adult; Agglutination; Angina Pectoris; Anticholesteremic Agents; Arteriosclerosis; Bo | 1968 |
[Simultaneous occurrence of diabetes insipidus and diabetes mellitus and their treatement with chlorpropamide].
Topics: Adult; Chlorpropamide; Diabetes Complications; Diabetes Insipidus; Diabetes Mellitus; Female; Humans | 1968 |
[2 cases of hypoglycemic coma in patients treated with oral hypoglycemic agents].
Topics: Adult; Aged; Chlorpropamide; Coma; Diabetes Complications; Humans; Hypoglycemia; Male | 1966 |