chlorpropamide has been researched along with Autoimmune Diabetes in 36 studies
Chlorpropamide: A sulfonylurea hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. (From Martindale, The Extra Pharmacopoeia, 30th ed, p277)
chlorpropamide : An N-sulfonylurea that is urea in which a hydrogen attached to one of the nitrogens is substituted by 4-chlorobenzenesulfonyl group and a hydrogen attached to the other nitrogen is substituted by propyl group. Chlorpropamide is a hypoglycaemic agent used in the treatment of type 2 (non-insulin-dependent) diabetes mellitus not responding to dietary modification.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An epidemiological study was carried out to compare the prevalence of facial flushing in non-diabetics, patients with insulin dependent diabetes, and patients with non-insulin dependent diabetes in response to 40 ml sherry taken 12 hours after 250 mg chlorpropamide or placebo, administered double blind in randomised order." | 9.05 | Epidemiological study of prevalence of chlorpropamide alcohol flushing in insulin dependent diabetics, non-insulin dependent diabetics, and non-diabetics. ( Jarrett, RJ; Keen, H; Marsden, P; Murrells, T; Ng Tang Fui, S; Stott, R; Strakosch, C, 1983) |
| "An epidemiological study was carried out to compare the prevalence of facial flushing in non-diabetics, patients with insulin dependent diabetes, and patients with non-insulin dependent diabetes in response to 40 ml sherry taken 12 hours after 250 mg chlorpropamide or placebo, administered double blind in randomised order." | 5.05 | Epidemiological study of prevalence of chlorpropamide alcohol flushing in insulin dependent diabetics, non-insulin dependent diabetics, and non-diabetics. ( Jarrett, RJ; Keen, H; Marsden, P; Murrells, T; Ng Tang Fui, S; Stott, R; Strakosch, C, 1983) |
| "After the observation of decreasing insulin resistance in a diabetic patient during treatment with mebendazole for nematosis, we investigated the effect of mebendazole on metabolic control in six Type 1 (insulin-dependent) and six Type 2 (non-insulin-dependent) diabetic patients, eight of whom were chronically resistant to conventional treatment." | 3.67 | Improvement of metabolic control in diabetic patients during mebendazole administration: preliminary studies. ( Boden, G; Caprio, S; Dayal, VK; Hoeldtke, RD; Mozzoli, MA; Owen, OE; Ray, TK; Reichard, GA; Shuman, CR; Smith, RH, 1984) |
| "Among 53 patients with noninsulin-dependent diabetes (NIDD), chlorpropamide alcohol flushing (CPAF) was more prevalent than among 18 patients with insulin-dependent diabetes (64 vs." | 3.67 | Prevalence of chlorpropamide alcohol flush in Jewish Israeli diabetics. The role of serum chlorpropamide concentrations. ( Almog, S; Berezin, M; Brazu-Albu, J; Segal, P, 1985) |
| "Chlorpropamide was found to have a generalized cholesterol lowering effect (progressive significant fall in mean total cholesterol, LDL-C, HDL-C, and HDL3-C) with no significant change in the ratio of high-density lipoprotein to low-density lipoprotein cholesterol which was independent of insulin secretion." | 1.27 | Chlorpropamide lowers serum and lipoprotein cholesterol in insulin-dependent diabetes. ( Elkeles, RS; Richmond, W; Seviour, PW; Teal, TK, 1986) |
| "In comparison to NIDDM of maturity onset (40/8), IDDM (40/6) and healthy controls (40/2) the frequency of positive CPAF showed no significant differences." | 1.26 | [Chlorpropamide-alcohol flush test in non-insulin-dependent diabetes mellitus in young age (MODY type)]. ( Adolph, W; Panzram, G, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 35 (97.22) | 18.7374 |
| 1990's | 1 (2.78) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| FIORIO, C | 1 |
| CASTELLAZZI, R | 1 |
| MOSS, JM | 1 |
| DELAWTER, DE | 1 |
| GALLAGHER, EJ | 1 |
| KEEN, H | 4 |
| Mutch, WJ | 1 |
| Stowers, JM | 1 |
| Jarrett, RJ | 2 |
| Guillausseau, PJ | 2 |
| Akoka, C | 2 |
| Lubetzki, J | 2 |
| Caprio, S | 1 |
| Ray, TK | 1 |
| Boden, G | 1 |
| Reichard, GA | 1 |
| Shuman, CR | 1 |
| Smith, RH | 1 |
| Mozzoli, MA | 1 |
| Dayal, VK | 1 |
| Hoeldtke, RD | 1 |
| Owen, OE | 1 |
| Rogoziński, R | 1 |
| Patewicz, K | 1 |
| Torzecki, Z | 1 |
| Jurga-Waniek, K | 1 |
| Mroszczyk, M | 1 |
| Błaszczyk, M | 1 |
| Pontiroli, AE | 1 |
| Alberetto, M | 1 |
| Bertoletti, A | 1 |
| Baio, G | 1 |
| Pozza, G | 1 |
| Ng Tang Fui, S | 1 |
| Strakosch, C | 1 |
| Murrells, T | 1 |
| Marsden, P | 2 |
| Stott, R | 1 |
| Babadzhanova, GIu | 1 |
| Mazovetskiĭ, AG | 1 |
| Kuraeva, TL | 1 |
| Mukhamedov, KhA | 1 |
| Groop, L | 1 |
| Eriksson, CJ | 1 |
| Wåhlin-Boll, E | 1 |
| Melander, A | 1 |
| MacDonald, MJ | 1 |
| Fui, SN | 1 |
| Jarrett, J | 1 |
| Gossain, V | 1 |
| Panzram, G | 1 |
| Adolph, W | 1 |
| Dreyer, M | 1 |
| Kühnau, J | 1 |
| Rüdiger, HW | 1 |
| Fajans, SS | 1 |
| Cloutier, MC | 1 |
| Crowther, RL | 1 |
| Shen, SW | 1 |
| Bressler, R | 1 |
| Teuscher, A | 1 |
| Radder, JK | 1 |
| Gill, G | 1 |
| Seviour, PW | 1 |
| Teal, TK | 1 |
| Richmond, W | 1 |
| Elkeles, RS | 1 |
| Moore, DC | 1 |
| Stanisstreet, M | 1 |
| Clarke, CA | 1 |
| Beck, F | 1 |
| Hipkin, LJ | 1 |
| Bońkowska, M | 1 |
| Sroczyński, J | 1 |
| Szramek-Urbaniak, A | 1 |
| Jerntorp, P | 1 |
| Ohlin, H | 1 |
| Sundkvist, G | 1 |
| Almér, LO | 1 |
| Sabán, J | 1 |
| Ordóñez, A | 1 |
| Navascués, I | 1 |
| Suárez Terry, R | 1 |
| Serrano Ríos, M | 1 |
| Dempe, A | 1 |
| Jordan, A | 1 |
| Segal, P | 1 |
| Brazu-Albu, J | 1 |
| Almog, S | 1 |
| Berezin, M | 1 |
| Ser, I | 1 |
| Tattersall, RB | 1 |
| Dacou-Voutetakis, C | 1 |
| Constantinidis, M | 1 |
| Moschos, A | 1 |
| Vlachou, C | 1 |
| Matsaniotis, N | 1 |
| Bretz, GW | 1 |
| Baghdassarian, A | 1 |
| Graber, JD | 1 |
| Zacherle, BJ | 1 |
| Norum, RA | 1 |
| Blizzard, RM | 1 |
| Crawford, JD | 1 |
| Bode, HH | 1 |
| Naccarato, R | 1 |
| Broglio, G | 1 |
| Sirigu, F | 1 |
| Previato, G | 1 |
| Fameli, O | 1 |
4 reviews available for chlorpropamide and Autoimmune Diabetes
| Article | Year |
|---|---|
Clinical and etiological heterogeneity of idiopathic diabetes mellitus. The banting memorial lecture.
Topics: Adenoma, Islet Cell; Adult; Antibodies, Viral; Autoantibodies; Cell Adhesion; Chlorpropamide; Chromo | 1979 |
Clinical pharmacology of oral antidiabetic agents (second of two parts).
Topics: Administration, Oral; Cardiovascular Diseases; Chlorpropamide; Clinical Trials as Topic; Diabetes Me | 1977 |
Practical management of diabetes in the tropics.
Topics: Blood Glucose; Chlorpropamide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Glucose | 1990 |
[Flush induced by chlorpropamide-alcohol (CAF): a genetic marker of diabetes mellitus or an undesirable effect of the drug?].
Topics: Acetaldehyde; Alcohol Drinking; Chlorpropamide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2 | 1985 |
3 trials available for chlorpropamide and Autoimmune Diabetes
| Article | Year |
|---|---|
Epidemiological study of prevalence of chlorpropamide alcohol flushing in insulin dependent diabetics, non-insulin dependent diabetics, and non-diabetics.
Topics: Adult; Aged; Alcoholic Beverages; Chlorpropamide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type | 1983 |
Test for chlorpropamide-alcohol flush becomes positive after prolonged chlorpropamide treatment in insulin-dependent and non-insulin-dependent diabetics.
Topics: Alcoholic Beverages; Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diagnosis, Differ | 1983 |
Clinical pharmacology of oral antidiabetic agents (second of two parts).
Topics: Administration, Oral; Cardiovascular Diseases; Chlorpropamide; Clinical Trials as Topic; Diabetes Me | 1977 |
30 other studies available for chlorpropamide and Autoimmune Diabetes
| Article | Year |
|---|---|
[CLINICAL EVALUATION OF AN ORAL ANTIDIABETIC CONSISTING OF THE ASSOCIATION OF A SULFONYLUREA AND A BIGUANIDE].
Topics: Adolescent; Biguanides; Child; Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Geriatr | 1964 |
ORAL HYPOGLYCEMIC DRUGS: COMPARATIVE EVALUATION OF TOLBUTAMIDE, CHLORPROPAMIDE AND PHENFORMIN.
Topics: Alkaline Phosphatase; Biomedical Research; Blood Glucose; Chlorpropamide; Diabetes Mellitus; Diabete | 1964 |
THE FAMILY DOCTOR AND THE DIABETIC.
Topics: Acidosis; Adolescent; Child; Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetic | 1965 |
Reversible mild diabetes in children after treatment with chlorpropamide.
Topics: Administration, Oral; Adolescent; Child; Child, Preschool; Chlorpropamide; Diabetes Mellitus, Type 1 | 1980 |
Reversal of "mild" diabetes by chlorpropamide.
Topics: Child; Chlorpropamide; Diabetes Mellitus, Type 1; Humans | 1980 |
[The alcohol-chlorpropamide test. Study and diagnostic value of changes in cutaneous temperature].
Topics: Chlorpropamide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Ethanol; Face; Flushing; Human | 1984 |
Improvement of metabolic control in diabetic patients during mebendazole administration: preliminary studies.
Topics: Adult; Benzimidazoles; Blood Glucose; C-Peptide; Chlorpropamide; Diabetes Mellitus, Type 1; Diabetes | 1984 |
[Karyometric study of hepatocytes in diabetic patients treated with insulin or chlorpropamide].
Topics: Cell Nucleus; Chlorpropamide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Humans; Insulin; | 1984 |
Sulfonylureas enhance in vivo the effectiveness of insulin in type 1 (insulin dependent) diabetes mellitus.
Topics: Adolescent; Adult; Chlorpropamide; Diabetes Mellitus, Type 1; Drug Interactions; Female; Glipizide; | 1984 |
[The chlorpropamide-alcohol test in diabetes mellitus].
Topics: Adult; Chlorpropamide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagnosis, Differential | 1984 |
Chlorpropamide-alcohol flush: significance of body weight, sex and serum chlorpropamide level.
Topics: Body Weight; Chlorpropamide; Diabetes Mellitus, Type 1; Drug Interactions; Ethanol; Female; Flushing | 1984 |
[Facial vasomotor flushing due to alcohol-chlorpropamide. Prevalence in diabetic and non-diabetic patients].
Topics: Adult; Aged; Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2 | 1984 |
Etiology and classification of diabetes in children. Practical genetics and prognosis counseling.
Topics: Adolescent; Adult; Animals; Child; Child, Preschool; Chlorpropamide; Diabetes Mellitus, Type 1; Diab | 1983 |
[Chlorpropamide-alcohol flush test in non-insulin-dependent diabetes mellitus in young age (MODY type)].
Topics: Adolescent; Adult; Aged; Child; Chlorpropamide; Diabetes Mellitus, Type 1; Ethanol; Female; Humans; | 1982 |
Chlorpropamide-alcohol flushing is not useful for individual genetic counseling of diabetic patients.
Topics: Adolescent; Adult; Blushing; C-Peptide; Child; Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, | 1980 |
[The biological effect of purely synthetic human insulin in patients with diabetes mellitus].
Topics: Adult; Aged; Buformin; Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; Hormone | 1979 |
[Diabetes mellitus and heredity].
Topics: Adult; Child; Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Ethanol; HLA Antigens; H | 1979 |
Chlorpropamide lowers serum and lipoprotein cholesterol in insulin-dependent diabetes.
Topics: Adult; Blood Glucose; Chlorpropamide; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mell | 1986 |
Effect on rat embryos of in vitro culture in sera from human diabetic patients.
Topics: Animals; Chlorpropamide; Culture Media; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Embryo | 1987 |
[Value of the chlorpropamide-alcohol test for determining the type of diabetes mellitus].
Topics: Adolescent; Adult; Aged; Chlorpropamide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagn | 1987 |
[Studies of the functional state of blood vessels in various types of diabetes mellitus using the chlorpropamide-alcohol test].
Topics: Adult; Aged; Chlorpropamide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Ethanol; Humans; | 1986 |
Effects of chlorpropamide and alcohol on aldehyde dehydrogenase activity and blood acetaldehyde concentration.
Topics: Acetaldehyde; Adult; Aged; Aldehyde Dehydrogenase; Chlorpropamide; Diabetes Mellitus, Type 1; Diabet | 1986 |
[Frequency of a positive result in the chlorpropamide-alcohol flush test in type I and type II diabetes].
Topics: Adolescent; Adult; Aged; Chlorpropamide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagn | 1986 |
Prevalence of chlorpropamide alcohol flush in Jewish Israeli diabetics. The role of serum chlorpropamide concentrations.
Topics: Adult; Aged; Alcohol Drinking; Body Temperature; Chlorpropamide; Diabetes Mellitus, Type 1; Diabetes | 1985 |
Plasma-insulin in a young diabetic after 13 years' oral therapy.
Topics: Administration, Oral; Adolescent; Child; Chlorpropamide; Diabetes Mellitus, Type 1; Humans; Insulin; | 1971 |
Mild familial diabetes with dominant inheritance.
Topics: Acetohexamide; Adolescent; Adult; Aged; Blood Glucose; Carbohydrates; Child; Chlorpropamide; Diabete | 1974 |
Diabetes mellitus following mumps. Insulin reserve.
Topics: Blood Glucose; Child; Child, Preschool; Chlorpropamide; Diabetes Mellitus, Type 1; Female; Glucose; | 1974 |
Coexistence of diabetes mellitus and insipidus and optic atrophy in two male siblings. Studies and review of literature.
Topics: Adolescent; Chlorpropamide; Diabetes Insipidus; Diabetes Mellitus, Type 1; Genes, Recessive; Humans; | 1970 |
Diabetes and the amplifier hypothesis.
Topics: Child; Chlorpropamide; Diabetes Insipidus; Diabetes Mellitus; Diabetes Mellitus, Type 1; Humans; Ins | 1970 |
[Some advantages of the combination of phenformin and chlorpropamide in the therapy of diabetes mellitus].
Topics: Adolescent; Adult; Aged; Child; Chlorpropamide; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female | 1965 |