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chlorpropamide and Alcohol Drinking

chlorpropamide has been researched along with Alcohol Drinking in 16 studies

Chlorpropamide: A sulfonylurea hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. (From Martindale, The Extra Pharmacopoeia, 30th ed, p277)
chlorpropamide : An N-sulfonylurea that is urea in which a hydrogen attached to one of the nitrogens is substituted by 4-chlorobenzenesulfonyl group and a hydrogen attached to the other nitrogen is substituted by propyl group. Chlorpropamide is a hypoglycaemic agent used in the treatment of type 2 (non-insulin-dependent) diabetes mellitus not responding to dietary modification.

Alcohol Drinking: Behaviors associated with the ingesting of ALCOHOLIC BEVERAGES, including social drinking.

Research Excerpts

ExcerptRelevanceReference
"It has been suggested that raised post-ethanol plasma acetaldehyde levels, from inhibition of aldehyde dehydrogenase, underlie the liability to chlorpropamide, alcohol flushing (CPAF)."5.07The formation of acetate from ethanol with and without prior chlorpropamide intake in diabetic and non-diabetic subjects. ( Akanji, AO; Hockaday, TD, 1991)
"Among 53 patients with noninsulin-dependent diabetes (NIDD), chlorpropamide alcohol flushing (CPAF) was more prevalent than among 18 patients with insulin-dependent diabetes (64 vs."3.67Prevalence of chlorpropamide alcohol flush in Jewish Israeli diabetics. The role of serum chlorpropamide concentrations. ( Almog, S; Berezin, M; Brazu-Albu, J; Segal, P, 1985)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199015 (93.75)18.7374
1990's1 (6.25)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Johnston, C2
Wiles, PG2
Pyke, DA5
Waldhäusl, W1
Groop, L1
Eriksson, CJ1
Huupponen, R1
Ylikahri, R1
Pelkonen, R1
Hillson, RM2
Hockaday, TD3
Barnett, AH3
Leslie, RD1
Mace, PJ1
Jerntorp, P2
Almér, LO2
Hulthén, UL1
Yamamoto, T1
Akanji, AO1
Ting, HH1
Smith, RF1
Yajnik, CS1
Crabbe, J1
Saunders, JB1
Ricciardi, BR1
Hopkinson, DA1
Sabán, J1
Ordóñez, A1
Navascués, I1
Suárez Terry, R1
Serrano Ríos, M1
Roe, DA1
Segal, P1
Brazu-Albu, J1
Almog, S1
Berezin, M1

Reviews

4 reviews available for chlorpropamide and Alcohol Drinking

ArticleYear
Chlorpropamide--alcohol flush: the case in favour.
    Diabetologia, 1984, Volume: 26, Issue:1

    Topics: Acetaldehyde; Alcohol Drinking; Biomechanical Phenomena; Chlorpropamide; Diabetic Angiopathies; Drug

1984
The chlorpropamide alcohol flush.
    Clinical science (London, England : 1979), 1984, Volume: 67, Issue:4

    Topics: Acetaldehyde; Alcohol Drinking; Chlorpropamide; Diabetes Mellitus, Type 2; Dose-Response Relationshi

1984
[Flush induced by chlorpropamide-alcohol (CAF): a genetic marker of diabetes mellitus or an undesirable effect of the drug?].
    Revista clinica espanola, 1985, Volume: 176, Issue:3

    Topics: Acetaldehyde; Alcohol Drinking; Chlorpropamide; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2

1985
Drug-food and drug-nutrient interactions.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 1985, Volume: 5, Issue:6

    Topics: Alcohol Drinking; Aldehyde Dehydrogenase; Anticonvulsants; Chlorpropamide; Contraceptives, Oral; Dru

1985

Trials

2 trials available for chlorpropamide and Alcohol Drinking

ArticleYear
Roles of chlorpropamide, alcohol and acetaldehyde in determining the chlorpropamide-alcohol flush.
    Diabetologia, 1984, Volume: 26, Issue:1

    Topics: Acetaldehyde; Adult; Alcohol Drinking; Chlorpropamide; Diabetes Mellitus, Type 2; Dose-Response Rela

1984
The formation of acetate from ethanol with and without prior chlorpropamide intake in diabetic and non-diabetic subjects.
    African journal of medicine and medical sciences, 1991, Volume: 20, Issue:2

    Topics: Acetates; Adult; Alcohol Drinking; Chlorpropamide; Diabetes Mellitus, Type 2; Ethanol; Female; Flush

1991

Other Studies

10 other studies available for chlorpropamide and Alcohol Drinking

ArticleYear
To flush or not to flush? Comments on the chlorpropamide-alcohol flush.
    Diabetologia, 1984, Volume: 26, Issue:1

    Topics: Alcohol Drinking; Chlorpropamide; Diabetes Mellitus, Type 2; Drug Interactions; Flushing; Humans; Va

1984
Chlorpropamide-alcohol flush: a critical reappraisal.
    Diabetologia, 1984, Volume: 26, Issue:1

    Topics: Adult; Alcohol Drinking; Biomechanical Phenomena; Chlorpropamide; Diabetes Mellitus, Type 2; Drug In

1984
Chlorpropamide-alcohol flushing and proteinuria in non-insulin-dependent diabetics.
    British medical journal (Clinical research ed.), 1981, Feb-14, Volume: 282, Issue:6263

    Topics: Alcohol Drinking; Chlorpropamide; Diabetes Mellitus; Diabetic Nephropathies; Face; Humans; Hyperemia

1981
Chlorpropamide-alcohol flushing and microangiopathy in insulin-dependent diabetes.
    British medical journal (Clinical research ed.), 1981, Feb-14, Volume: 282, Issue:6263

    Topics: Adolescent; Adult; Alcohol Drinking; Child; Chlorpropamide; Diabetes Mellitus; Diabetic Angiopathies

1981
Chlorpropamide-alcohol flushing in relation to macroangiopathy and peripheral neuropathy in non-insulin dependent diabetes.
    Acta medica Scandinavica. Supplementum, 1981, Volume: 656

    Topics: Aged; Alcohol Drinking; Chlorpropamide; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Neuropath

1981
Chlorpropamide-alcohol flushing and blood kinins.
    Acta medica Scandinavica. Supplementum, 1981, Volume: 656

    Topics: Alcohol Drinking; Chlorpropamide; Diabetes Mellitus; Facial Dermatoses; Humans; Kinins; Pilot Projec

1981
Letter: Diabetes insipidus and drinking alcohol.
    The New England journal of medicine, 1976, Jan-01, Volume: 294, Issue:1

    Topics: Alcohol Drinking; Chlorpropamide; Diabetes Insipidus; Ethanol; Humans

1976
Erythrocyte aldehyde dehydrogenase, plasma chlorpropamide concentrations and the chlorpropamide alcohol flush.
    Diabete & metabolisme, 1987, Volume: 13, Issue:1

    Topics: Alcohol Drinking; Aldehyde Dehydrogenase; Chlorpropamide; Erythrocytes; Female; Flushing; Humans; Ma

1987
Chlorpropamide-alcohol flush reaction and isoenzyme profiles of alcohol dehydrogenase and aldehyde dehydrogenase.
    Clinical science (London, England : 1979), 1986, Volume: 71, Issue:5

    Topics: Alcohol Dehydrogenase; Alcohol Drinking; Aldehyde Dehydrogenase; Chlorpropamide; Ethanol; Female; Fl

1986
Prevalence of chlorpropamide alcohol flush in Jewish Israeli diabetics. The role of serum chlorpropamide concentrations.
    Israel journal of medical sciences, 1985, Volume: 21, Issue:2

    Topics: Adult; Aged; Alcohol Drinking; Body Temperature; Chlorpropamide; Diabetes Mellitus, Type 1; Diabetes

1985