Page last updated: 2024-10-25

chlorpropamide and Agranulocytosis

chlorpropamide has been researched along with Agranulocytosis in 9 studies

Chlorpropamide: A sulfonylurea hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. (From Martindale, The Extra Pharmacopoeia, 30th ed, p277)
chlorpropamide : An N-sulfonylurea that is urea in which a hydrogen attached to one of the nitrogens is substituted by 4-chlorobenzenesulfonyl group and a hydrogen attached to the other nitrogen is substituted by propyl group. Chlorpropamide is a hypoglycaemic agent used in the treatment of type 2 (non-insulin-dependent) diabetes mellitus not responding to dietary modification.

Agranulocytosis: A decrease in the number of GRANULOCYTES; (BASOPHILS; EOSINOPHILS; and NEUTROPHILS).

Research Excerpts

ExcerptRelevanceReference
"A fatal case of agranulocytosis due to chlorpromazine is reported."7.64A drug-specific leuco-agglutinin in a fatal case of agranulocytosis due to chlorpromazine. ( GARZON, FL; HEWLETT, JS; HOFFMAN, GC, 1963)
"A fatal case of agranulocytosis due to chlorpromazine is reported."3.64A drug-specific leuco-agglutinin in a fatal case of agranulocytosis due to chlorpromazine. ( GARZON, FL; HEWLETT, JS; HOFFMAN, GC, 1963)
"Twenty-three episodes of drug-induced agranulocytosis admitted to the Beilinson Medical Center between 1960-1972 are reported."1.25Drug-induced agranulocytosis. A survey of twenty-three episodes. ( de Vries, A; Mintz, U; Pinkhas, J; Shaklai, M, 1975)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19909 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
HOFFMAN, GC1
HEWLETT, JS1
GARZON, FL1
STEIN, JH1
HAMILTON, HE1
SHEETS, RF1
HAUNZ, EA1
CORNATZER, WE1
LUPER, M1
FORKS, G1
KARLIN, H1
Kanefsky, TM1
Medoff, SJ1
Mintz, U1
Shaklai, M1
Pinkhas, J1
de Vries, A1
Tucker, SC1
Lynch, JP1
Ansell, BF1
Levitt, LJ1
Traissac, FJ1
Dangoumau, J1

Reviews

1 review available for chlorpropamide and Agranulocytosis

ArticleYear
[Cytopenias caused by hypoglycemic sulfonamides].
    Journees annuelles de diabetologie de l'Hotel-Dieu, 1968, Volume: 9

    Topics: Aged; Agranulocytosis; Anemia, Aplastic; Anemia, Hemolytic; Carbutamide; Chlorpropamide; Female; Hum

1968

Other Studies

8 other studies available for chlorpropamide and Agranulocytosis

ArticleYear
A drug-specific leuco-agglutinin in a fatal case of agranulocytosis due to chlorpromazine.
    Journal of clinical pathology, 1963, Volume: 16

    Topics: Agglutinins; Agranulocytosis; Antibodies; Asthma; Chlorpromazine; Chlorpropamide; Drug Hypersensitiv

1963
AGRANULOCYTOSIS CAUSED BY CHLORPROPAMIDE. A CASE REPORT WITH CONFIRMATION BY LEUKOAGGLUTINATION STUDIES.
    Archives of internal medicine, 1964, Volume: 113

    Topics: Agranulocytosis; Chlorpropamide; Diagnosis; Geriatrics; Hemagglutination; Leukocytes; Pathology; Tox

1964
LIVER FUNCTION IN CHLORPROPAMIDE THERAPY. FIVE YEAR CLINICAL STUDY OF 181 PATIENTS.
    JAMA, 1964, Apr-20, Volume: 188

    Topics: Agranulocytosis; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Biomedical

1964
Fatal agranulocytosis following chlorpropamide treatment of diabetes. Report of a case.
    The New England journal of medicine, 1960, May-26, Volume: 262

    Topics: Agranulocytosis; Chlorpropamide; Diabetes Mellitus; Humans; Hypoglycemic Agents

1960
Stevens-Johnson syndrome and neutropenia with chlorpropamide therapy.
    Archives of internal medicine, 1980, Volume: 140, Issue:11

    Topics: Aged; Agranulocytosis; Chlorpropamide; Female; Humans; Hyperglycemia; Neutropenia; Stevens-Johnson S

1980
Drug-induced agranulocytosis. A survey of twenty-three episodes.
    Medecine interne, 1975, Volume: 13, Issue:3

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Aminopyrine; Anti-Infective Agents; Anti-Inflammatory Agen

1975
Chlorpropamide-induced agranulocytosis.
    JAMA, 1977, Aug-01, Volume: 238, Issue:5

    Topics: Aged; Agranulocytosis; Bone Marrow; Chlorpropamide; Diabetes Mellitus; Female; Humans; Leukocytes; R

1977
Chlorpropamide-induced pure white cell aplasia.
    Blood, 1987, Volume: 69, Issue:2

    Topics: Aged; Aged, 80 and over; Agranulocytosis; Bone Marrow Diseases; Chlorpropamide; Diabetes Mellitus, T

1987