chlorpropamide has been researched along with Adverse Drug Event in 17 studies
Chlorpropamide: A sulfonylurea hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. (From Martindale, The Extra Pharmacopoeia, 30th ed, p277)
chlorpropamide : An N-sulfonylurea that is urea in which a hydrogen attached to one of the nitrogens is substituted by 4-chlorobenzenesulfonyl group and a hydrogen attached to the other nitrogen is substituted by propyl group. Chlorpropamide is a hypoglycaemic agent used in the treatment of type 2 (non-insulin-dependent) diabetes mellitus not responding to dietary modification.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We proposed a systematic classification scheme using FDA-approved drug labeling to assess the DILI potential of drugs, which yielded a benchmark dataset with 287 drugs representing a wide range of therapeutic categories and daily dosage amounts." | 1.37 | FDA-approved drug labeling for the study of drug-induced liver injury. ( Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (58.82) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (5.88) | 29.6817 |
| 2010's | 6 (35.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, M | 1 |
| Vijay, V | 1 |
| Shi, Q | 2 |
| Liu, Z | 2 |
| Fang, H | 2 |
| Tong, W | 2 |
| Dawson, S | 1 |
| Stahl, S | 1 |
| Paul, N | 1 |
| Barber, J | 1 |
| Kenna, JG | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Sakatis, MZ | 1 |
| Reese, MJ | 1 |
| Harrell, AW | 1 |
| Taylor, MA | 1 |
| Baines, IA | 1 |
| Chen, L | 1 |
| Bloomer, JC | 1 |
| Yang, EY | 1 |
| Ellens, HM | 1 |
| Ambroso, JL | 1 |
| Lovatt, CA | 1 |
| Ayrton, AD | 1 |
| Clarke, SE | 1 |
| Morgan, RE | 1 |
| van Staden, CJ | 1 |
| Chen, Y | 1 |
| Kalyanaraman, N | 1 |
| Kalanzi, J | 1 |
| Dunn, RT | 1 |
| Afshari, CA | 1 |
| Hamadeh, HK | 1 |
| Donatelli, NS | 1 |
| Somes, J | 1 |
| Clark, BG | 1 |
| Vestal, RE | 1 |
| Erskine, IA | 1 |
| Mackay, JM | 1 |
| Fox, DP | 1 |
| Knight, EL | 1 |
| Avorn, J | 1 |
| Roe, DA | 1 |
| Hallberg, L | 1 |
| Lundborg, P | 1 |
| Hodkinson, HM | 1 |
| Wepler, R | 1 |
| Rommel, K | 1 |
| Moses, AM | 1 |
| Miller, M | 1 |
| de Matteis, F | 1 |
| Meiring, Pde V | 1 |
| da Cruz, I | 1 |
| Leopold, IH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evidence-based Assessment of Medication Sensitivity in Acute Hepatic Porphyria[NCT03906214] | 60 participants (Actual) | Observational | 2019-04-03 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for chlorpropamide and Adverse Drug Event
| Article | Year |
|---|---|
Beers list: what's NOT on "tap" for the older adult.
Topics: Aged, 80 and over; Antiemetics; Antihypertensive Agents; Arthritis; Chlorpropamide; Confusion; Diabe | 2013 |
Drug-food and drug-nutrient interactions.
Topics: Alcohol Drinking; Aldehyde Dehydrogenase; Anticonvulsants; Chlorpropamide; Contraceptives, Oral; Dru | 1985 |
[Drugs and parameters in the laboratory medicine].
Topics: Aminosalicylic Acids; Aspirin; Blood Cell Count; Chlorpromazine; Chlorpropamide; Circadian Rhythm; C | 1973 |
Drug-induced dilutional hyponatremia.
Topics: Acetaminophen; Amitriptyline; Animals; Anura; Body Fluids; Carbamazepine; Chlorpropamide; Clofibrate | 1974 |
Disturbances of liver porphyrin metabolism caused by drugs.
Topics: Animals; Chlorpropamide; Drug-Related Side Effects and Adverse Reactions; Estrogens; Griseofulvin; H | 1967 |
12 other studies available for chlorpropamide and Adverse Drug Event
| Article | Year |
|---|---|
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Des | 2011 |
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2012 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily | 2013 |
Adverse drug reactions in the elderly: case studies.
Topics: Acetazolamide; Aged; Anemia, Hemolytic; Bromocriptine; Captopril; Chlorpropamide; Cimetidine; Clonid | 1984 |
Monitoring patients on long-term drug therapy for genotoxic effects.
Topics: Atenolol; Azathioprine; Cells, Cultured; Chlorpropamide; Chronic Disease; Drug-Related Side Effects | 1984 |
Quality indicators for appropriate medication use in vulnerable elders.
Topics: Aged; Analgesics, Opioid; Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Barbiturates; Ch | 2001 |
[Local reporting of adverse effects--an experimental work at the main hospital].
Topics: Aged; Chlorpropamide; Diabetes Mellitus; Dicumarol; Drug Interactions; Drug Therapy, Combination; Dr | 1974 |
Biochemical side effects of drugs in the elderly.
Topics: Aged; Calcium; Chlorpropamide; Diethylstilbestrol; Drug-Related Side Effects and Adverse Reactions; | 1974 |
To the Editor. Adverse effects from drugs.
Topics: Chlorpropamide; Digoxin; Drug-Related Side Effects and Adverse Reactions; Indomethacin; Penicillins; | 1969 |
Ocular complications of drugs. Visual changes.
Topics: Adrenal Cortex Hormones; Cardiac Glycosides; Chloramphenicol; Chlorpropamide; Drug-Related Side Effe | 1968 |