chlorpromazine has been researched along with Xerostomia in 8 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Xerostomia: Decreased salivary flow.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to compare the efficacy of olanzapine with that of chlorpromazine plus benztropine in patients with treatment-resistant schizophrenia." | 9.08 | Olanzapine compared with chlorpromazine in treatment-resistant schizophrenia. ( Bartko, JJ; Conley, RR; Gounaris, C; Hegerty, J; Lingle, J; Love, R; Peszke, M; Richardson, C; Tamminga, CA; Zaremba, S, 1998) |
| "To review the effects in clinical response of flupenthixol and low-potency antipsychotics for people with schizophrenia." | 8.90 | Flupenthixol versus low-potency first-generation antipsychotic drugs for schizophrenia. ( Dold, M; Engel, RR; Leucht, S; Tardy, M, 2014) |
| "The present study was performed to assess the effects of pilocarpine hydrochloride ((3S,4R)-3-ethyl-dihydro-4-[(1-methyl-1H-imidazole-5-yl)methyl]-2(3H)-furanone monohydrochloride, CAS 54-71-7) and cevimeline ((+/-)-cis-2-methylspiro[1,3-oxathiolane-5,3'-quinuclidine] hydrochloride, hemihydrate, CAS 153504-70-2), muscarinic receptor agonists, on salivary secretion from the submandibular/sublingual (SM/SL) glands in normal rats and in rats with xerostomia induced by X-ray (15 Gy) irradiation." | 7.72 | Effects of pilocarpine hydrochloride and cevimeline on submandibular/sublingual salivation in rat xerostomia model produced by X-ray irradiation. ( Asari, T; Kojima, M; Kusama, H; Maruyama, K; Omori, Y; Shibata, N, 2003) |
| "The purpose of this study was to compare the efficacy of olanzapine with that of chlorpromazine plus benztropine in patients with treatment-resistant schizophrenia." | 5.08 | Olanzapine compared with chlorpromazine in treatment-resistant schizophrenia. ( Bartko, JJ; Conley, RR; Gounaris, C; Hegerty, J; Lingle, J; Love, R; Peszke, M; Richardson, C; Tamminga, CA; Zaremba, S, 1998) |
| "To review the effects in clinical response of flupenthixol and low-potency antipsychotics for people with schizophrenia." | 4.90 | Flupenthixol versus low-potency first-generation antipsychotic drugs for schizophrenia. ( Dold, M; Engel, RR; Leucht, S; Tardy, M, 2014) |
| "The present study was performed to assess the effects of pilocarpine hydrochloride ((3S,4R)-3-ethyl-dihydro-4-[(1-methyl-1H-imidazole-5-yl)methyl]-2(3H)-furanone monohydrochloride, CAS 54-71-7) and cevimeline ((+/-)-cis-2-methylspiro[1,3-oxathiolane-5,3'-quinuclidine] hydrochloride, hemihydrate, CAS 153504-70-2), muscarinic receptor agonists, on salivary secretion from the submandibular/sublingual (SM/SL) glands in normal rats and in rats with xerostomia induced by X-ray (15 Gy) irradiation." | 3.72 | Effects of pilocarpine hydrochloride and cevimeline on submandibular/sublingual salivation in rat xerostomia model produced by X-ray irradiation. ( Asari, T; Kojima, M; Kusama, H; Maruyama, K; Omori, Y; Shibata, N, 2003) |
| "Polydipsia was the most prevalent (24, 60." | 1.51 | Adverse drug reactions experienced by out-patients taking chlorpromazine or haloperidol at Zomba Mental Hospital, Malawi. ( Chikowe, I; Domingo, M; Kampira, E; Mafuta, C; Mwakaswaya, V; Parveen, S, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chikowe, I | 1 |
| Domingo, M | 1 |
| Mwakaswaya, V | 1 |
| Parveen, S | 1 |
| Mafuta, C | 1 |
| Kampira, E | 1 |
| Tardy, M | 1 |
| Dold, M | 1 |
| Engel, RR | 1 |
| Leucht, S | 1 |
| Omori, Y | 1 |
| Asari, T | 1 |
| Maruyama, K | 1 |
| Kusama, H | 1 |
| Kojima, M | 1 |
| Shibata, N | 1 |
| Conley, RR | 1 |
| Tamminga, CA | 1 |
| Bartko, JJ | 1 |
| Richardson, C | 1 |
| Peszke, M | 1 |
| Lingle, J | 1 |
| Hegerty, J | 1 |
| Love, R | 1 |
| Gounaris, C | 1 |
| Zaremba, S | 1 |
| Milner, G | 1 |
| Kingstone, E | 1 |
| Kolivakis, T | 1 |
| Kossatz, I | 1 |
| Prien, RF | 1 |
| Caffey, EM | 1 |
| Klett, CJ | 1 |
| Scopp, IW | 1 |
| Heyman, RA | 1 |
2 reviews available for chlorpromazine and Xerostomia
| Article | Year |
|---|---|
Flupenthixol versus low-potency first-generation antipsychotic drugs for schizophrenia.
Topics: Akathisia, Drug-Induced; Antipsychotic Agents; Chlorpromazine; Flupenthixol; Humans; Randomized Cont | 2014 |
Gastro-intestinal side effects and psychotropic drugs.
Topics: Amitriptyline; Animals; Chlorpromazine; Constipation; Digestive System; Drug Synergism; Ethanol; Gas | 1969 |
3 trials available for chlorpromazine and Xerostomia
| Article | Year |
|---|---|
Olanzapine compared with chlorpromazine in treatment-resistant schizophrenia.
Topics: Adult; Akathisia, Drug-Induced; Analysis of Variance; Antipsychotic Agents; Basal Ganglia Diseases; | 1998 |
Double blind study of clopenthixol and chlorpromazine in acute hospitalized schizophrenics.
Topics: Acute Disease; Adolescent; Adult; Aged; Aspartate Aminotransferases; Blood Pressure; Body Weight; Ch | 1970 |
A comparison of lithium carbonate and chlorpromazine in the treatment of excited schizo-affectives. Report of the Veterans Administration and National Institute of Mental Health collaborative study group.
Topics: Adult; Affective Symptoms; Bipolar Disorder; Carbonates; Chlorpromazine; Evaluation Studies as Topic | 1972 |
3 other studies available for chlorpromazine and Xerostomia
| Article | Year |
|---|---|
Adverse drug reactions experienced by out-patients taking chlorpromazine or haloperidol at Zomba Mental Hospital, Malawi.
Topics: Adolescent; Adult; Antipsychotic Agents; Chlorpromazine; Cross-Sectional Studies; Erectile Dysfuncti | 2019 |
Effects of pilocarpine hydrochloride and cevimeline on submandibular/sublingual salivation in rat xerostomia model produced by X-ray irradiation.
Topics: Animals; Antipsychotic Agents; Body Temperature; Cardiovascular System; Central Nervous System; Chlo | 2003 |
Significance of dryness of the mouth caused by chlorpromazine.
Topics: Chlorpromazine; Dental Caries; Denture Retention; Diagnosis, Differential; Humans; Xerostomia | 1966 |