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chlorpromazine and Tuberculosis, Multidrug-Resistant

chlorpromazine has been researched along with Tuberculosis, Multidrug-Resistant in 2 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Tuberculosis, Multidrug-Resistant: Tuberculosis resistant to chemotherapy with two or more ANTITUBERCULAR AGENTS, including at least ISONIAZID and RIFAMPICIN. The problem of resistance is particularly troublesome in tuberculous OPPORTUNISTIC INFECTIONS associated with HIV INFECTIONS. It requires the use of second line drugs which are more toxic than the first line regimens. TB with isolates that have developed further resistance to at least three of the six classes of second line drugs is defined as EXTENSIVELY DRUG-RESISTANT TUBERCULOSIS.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kristiansen, JE1
Dastidar, SG1
Palchoudhuri, S1
Roy, DS1
Das, S1
Hendricks, O1
Christensen, JB1
Machado, D1
Couto, I1
Perdigão, J1
Rodrigues, L1
Portugal, I1
Baptista, P1
Veigas, B1
Amaral, L1
Viveiros, M1

Reviews

1 review available for chlorpromazine and Tuberculosis, Multidrug-Resistant

ArticleYear
Phenothiazines as a solution for multidrug resistant tuberculosis: From the origin to present.
    International microbiology : the official journal of the Spanish Society for Microbiology, 2015, Volume: 18, Issue:1

    Topics: Antipsychotic Agents; Antitubercular Agents; Chlorpromazine; Humans; Mycobacterium tuberculosis; Phe

2015

Other Studies

1 other study available for chlorpromazine and Tuberculosis, Multidrug-Resistant

ArticleYear
Contribution of efflux to the emergence of isoniazid and multidrug resistance in Mycobacterium tuberculosis.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: Antitubercular Agents; Bacterial Proteins; Biological Transport, Active; Carrier Proteins; Catalase;

2012