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chlorpromazine and Tremor

chlorpromazine has been researched along with Tremor in 49 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Tremor: Cyclical movement of a body part that can represent either a physiologic process or a manifestation of disease. Intention or action tremor, a common manifestation of CEREBELLAR DISEASES, is aggravated by movement. In contrast, resting tremor is maximal when there is no attempt at voluntary movement, and occurs as a relatively frequent manifestation of PARKINSON DISEASE.

Research Excerpts

ExcerptRelevanceReference
"A Parkinsonian-like tremor can be induced by a combined application of chlorpromazine and pentobarbitone in cats."7.68Parkinsonian-like tremor induced by a combined application of chlorpromazine and pentobarbitone in cats with left-paw preference. ( Cankaya, A; Gepdiremen, A; Kutlu, N; Tan, U, 1992)
"Drugs which reduce central catecholamine activity increased the tremorigenic action physostigmine (0."7.65Modification of the tremorigenic activity of physostigmine. ( Ambrani, LM; Van Woert, MH, 1972)
" The anti-tremor potency of the compounds was assessed from suppression of Tremorine-induced tremors in mice."7.64Relationship between anti-acetylcholine and anti-Tremorine activity in anti-parkinsonian and related drugs. ( AHMED, A; MARSHALL, PB, 1962)
"A Parkinsonian-like tremor can be induced by a combined application of chlorpromazine and pentobarbitone in cats."3.68Parkinsonian-like tremor induced by a combined application of chlorpromazine and pentobarbitone in cats with left-paw preference. ( Cankaya, A; Gepdiremen, A; Kutlu, N; Tan, U, 1992)
"Drugs which reduce central catecholamine activity increased the tremorigenic action physostigmine (0."3.65Modification of the tremorigenic activity of physostigmine. ( Ambrani, LM; Van Woert, MH, 1972)
" The anti-tremor potency of the compounds was assessed from suppression of Tremorine-induced tremors in mice."3.64Relationship between anti-acetylcholine and anti-Tremorine activity in anti-parkinsonian and related drugs. ( AHMED, A; MARSHALL, PB, 1962)

Research

Studies (49)

TimeframeStudies, this research(%)All Research%
pre-199045 (91.84)18.7374
1990's3 (6.12)18.2507
2000's1 (2.04)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
AHMED, A1
MARSHALL, PB1
KANE, FJ1
TAYLOR, TW1
LESLIE, GB1
MAXWELL, DR1
ROOS, BE1
STEG, G1
THEOBALD, W1
BUECH, O1
KUNZ, HA1
MORPURGO, C1
STENGER, EG1
WILHELMI, G1
DECIMA, EE1
HASLETT, WL1
Spoerlein, MT1
VanderWende, C1
Chetty, M2
Gouws, E1
Miller, R2
Moodley, SV1
Alpert, M1
Diamond, F1
Weisenfreund, J1
Taleporos, E1
Friedhoff, AJ1
Beasley, BA1
Ford, DH1
Duvoisin, RC1
Banna, NR1
Kurkjian, R1
Tan, U2
Gepdiremen, A2
Kutlu, N2
Cankaya, A1
Banoglu, N1
Hakola, A1
van Beek, MC1
Timmerman, H1
Van Woert, MH2
Sethy, VH1
Ambani, LM1
Elie, R1
Gagnon, MA1
Lamontagne, Y1
Tetreault, L1
Poirier, LJ1
Henatsch, HD1
ten Bruggencate, HG1
Bossmann, H1
Gumulka, W1
Kostowski, W1
Czlonkowski, A1
Vaupel, DB1
Martin, WR1
Connor, JD1
Rossi, GV1
Baker, WW1
Weissman, A1
Jurna, I1
Nell, T1
Schreyer, I1
Chibanguza, G1
McClelland, HA1
Blessed, G1
Bhate, S1
Ali, N1
Clarke, PA1
Schulterbrandt, JG1
Raskin, A1
Reatig, N1
Ambrani, LM1
Derkach, P1
Larochelle, L1
Bieger, D1
Hornykiewicz, O1
Laville, C1
Margarit, J1
Crane, GE1
Naranjo, ER1
Prien, RF1
Caffey, EM1
Klett, CJ1
Birkett, DP1
Boltuch, B1
Yen, HC1
Day, CA1
Goldstein, S1
Himwich, WA1
Leiner, K1
Stout, M1
Gurovich, IIa1
Fleĭs, EP1
Schneider, CW1
Chenoweth, MB1
Lippmann, W1
Stern, P2
Ialdygina, AS1
Pervomaĭskiĭ, BIa1
Antropov, IuA1
Ahlborg, U1
Holmstedt, B1
Lindgren, JE1
Nieschulz, O1
Schmersahl, P1
Muller, DJ1
Igić, R1
Dandiya, PC1
Menon, MK1
Meyer, HJ1
Dierstein, M1

Reviews

3 reviews available for chlorpromazine and Tremor

ArticleYear
Aging and the extrapyramidal system.
    The Medical clinics of North America, 1976, Volume: 60, Issue:6

    Topics: Aged; Aging; Basal Ganglia Diseases; Chlorpromazine; Chorea; Dopamine; Frontal Lobe; Gait; Haloperid

1976
Nervous mechanisms involved in experimentally induced extrapyramidal disturbances.
    Confinia neurologica, 1974, Volume: 36, Issue:4-6

    Topics: Animals; Basal Ganglia Diseases; Benztropine; Brain; Cats; Caudate Nucleus; Cerebellar Nuclei; Chlor

1974
Lithium carbonate. A survey of the history and current status of Lithium in treating mood disorders.
    Diseases of the nervous system, 1971, Volume: 32, Issue:8

    Topics: Bipolar Disorder; Carbonates; Chlorpromazine; Clinical Trials as Topic; Coma; Depression; Epilepsy;

1971

Trials

8 trials available for chlorpromazine and Tremor

ArticleYear
The use of a side effect as a qualitative indicator of plasma chlorpromazine levels.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1999, Volume: 9, Issue:1-2

    Topics: Adolescent; Adult; Antipsychotic Agents; Biotransformation; Blood Pressure; Chlorpromazine; Female;

1999
The neuroleptic hypothesis: study of the covariation of extrapyramidal and therapeutic drug effects.
    The British journal of psychiatry : the journal of mental science, 1978, Volume: 133

    Topics: Adolescent; Adult; Basal Ganglia Diseases; Chlorpromazine; Clinical Trials as Topic; Female; Humans;

1978
Pilot trials with long-acting pipotiazine injections.
    Acta psychiatrica Scandinavica. Supplementum, 1973, Volume: 241

    Topics: Adolescent; Adult; Antipsychotic Agents; Catatonia; Chlorpromazine; Clinical Trials as Topic; Drug E

1973
The abrupt withdrawal of antiparkinsonian drugs in schizophrenic patients.
    The British journal of psychiatry : the journal of mental science, 1974, Volume: 124, Issue:579

    Topics: Adult; Aged; Antiparkinson Agents; Basal Ganglia Diseases; Behavior; Chlorpromazine; Clinical Trials

1974
True and apparent side effects in a controlled trial of chlorpromazine and imipramine in depression.
    Psychopharmacologia, 1974, Volume: 38, Issue:4

    Topics: Adult; Agranulocytosis; Chlorpromazine; Clinical Trials as Topic; Depression; Dermatitis; Edema; Eva

1974
Motor disorders induced by neuroleptics: a proposed new classification.
    Archives of general psychiatry, 1971, Volume: 24, Issue:2

    Topics: Adolescent; Adult; Chlorpromazine; Clinical Trials as Topic; Dystonia Musculorum Deformans; Factor A

1971
Lithium carbonate. A survey of the history and current status of Lithium in treating mood disorders.
    Diseases of the nervous system, 1971, Volume: 32, Issue:8

    Topics: Bipolar Disorder; Carbonates; Chlorpromazine; Clinical Trials as Topic; Coma; Depression; Epilepsy;

1971
Chlorpromazine in geriatric psychiatry.
    Journal of the American Geriatrics Society, 1972, Volume: 20, Issue:8

    Topics: Aged; Chloral Hydrate; Chlorpromazine; Constipation; Dementia; Drug Synergism; Humans; Intracranial

1972

Other Studies

39 other studies available for chlorpromazine and Tremor

ArticleYear
Relationship between anti-acetylcholine and anti-Tremorine activity in anti-parkinsonian and related drugs.
    British journal of pharmacology and chemotherapy, 1962, Volume: 18

    Topics: Acetylcholine; Animals; Antiparkinson Agents; Antipsychotic Agents; Chlorpromazine; Cholinergic Anta

1962
An unusual reaction to combined imipramine-thorazine therapy.
    The American journal of psychiatry, 1963, Volume: 120

    Topics: Chlorpromazine; Imipramine; Reflex; Spasm; Speech Disorders; Tremor

1963
INHIBITION OF TREMORINE BY A GROUP OF NON-ANTI-PARKINSON PHENOTHIAZINE DERIVATIVES.
    Nature, 1964, Apr-04, Volume: 202

    Topics: Antipsychotic Agents; Atropine; Benactyzine; Chlorpromazine; Histamine H1 Antagonists; Mice; Muscle

1964
THE EFFECT OF L-3, 4-DIHYDROXYPHENYLALANINE AND DL-5-HYDROXYTRYPTOPHAN ON RIGIDITY AND TREMOR INDUCED BY RESERPINE, CHLORPROMAZINE AND PHENOXYBENZAMINE.
    Life sciences (1962), 1964, Volume: 3

    Topics: 5-Hydroxytryptophan; Amino Acids; Chlorpromazine; Dihydroxyphenylalanine; Dopamine; Inulin; Movement

1964
[COMPARATIVE PHARMACOLOGICAL INVESTIGATIONS WITH TOFRANIL, PERTOFRAN AND INSIDON].
    Archives internationales de pharmacodynamie et de therapie, 1964, Apr-01, Volume: 148

    Topics: Acetylcholine; Amphetamine; Amphetamines; Anesthetics; Animals; Antidepressive Agents; Catatonia; Ca

1964
EFFECTS OF OXOTREMORINE ON GAMMA FIBER ACTIVITY.
    Proceedings of the Western Pharmacology Society, 1964, Volume: 7

    Topics: Cats; Central Nervous System; Chlorpromazine; Decerebrate State; Muscles; Neurophysiology; Oxotremor

1964
Nature of the tremors induced by p-methoxydopamine.
    Life sciences, 1967, Oct-01, Volume: 6, Issue:19

    Topics: Animals; Chlorpromazine; Dopamine; Male; Methylation; Mice; Movement; Parasympatholytics; Phenobarbi

1967
Oral contraceptives increase the plasma concentrations of chlorpromazine.
    Therapeutic drug monitoring, 2001, Volume: 23, Issue:5

    Topics: Adult; Chlorpromazine; Contraceptives, Oral; Dopamine Antagonists; Drug Interactions; Dyskinesias; F

2001
Parkinsonism: animal analogues of the human disorder.
    Research publications - Association for Research in Nervous and Mental Disease, 1976, Volume: 55

    Topics: Animals; Butyrophenones; Chlorpromazine; Disease Models, Animal; Haplorhini; Hydroxydopamines; Levod

1976
A novel tremorigen antagonized by D-amphetamine.
    Brain research, 1975, Apr-04, Volume: 87, Issue:1

    Topics: Acetates; Aldehydes; Amines; Animals; Atropine; Calcium; Chlorpromazine; Dextroamphetamine; Diazepam

1975
Parkinsonian-like tremor induced by a combined application of chlorpromazine and pentobarbitone in cats with left-paw preference.
    The International journal of neuroscience, 1992, Volume: 63, Issue:3-4

    Topics: Animals; Atropine; Baclofen; Biperiden; Cats; Chlorpromazine; Feedback; Female; Functional Lateralit

1992
Intermittent tremor-bursts induced by chlorpromazine and pentobarbitone in guinea pigs: a new tremor model.
    The International journal of neuroscience, 1991, Volume: 61, Issue:3-4

    Topics: Acoustic Stimulation; Animals; Biperiden; Chlorpromazine; Disease Models, Animal; Guinea Pigs; Muscl

1991
Some benzhydryl derivatives as central dopamine receptor stimulating agents.
    The Journal of pharmacy and pharmacology, 1974, Volume: 26, Issue:1

    Topics: Animals; Apomorphine; Behavior, Animal; Benzyl Compounds; Brain; Chlorpromazine; Dihydroxyphenylalan

1974
Effect of phenothiazines on central cholinergic activity.
    Advances in biochemical psychopharmacology, 1974, Volume: 9, Issue:0

    Topics: Acetylcholine; Animals; Antipsychotic Agents; Basal Ganglia Diseases; Brain; Brain Chemistry; Chlorp

1974
The extrapyramidal neuroleptic syndrome: description and measurement.
    Current therapeutic research, clinical and experimental, 1973, Volume: 15, Issue:7

    Topics: Basal Ganglia Diseases; Chlorpromazine; Electromyography; Facial Muscles; Gait; Humans; Movement Dis

1973
[The importance of proprioceptors and muscle spindle gamma curve for curare tremor in the cat].
    Pflugers Archiv fur die gesamte Physiologie des Menschen und der Tiere, 1966, Volume: 292, Issue:4

    Topics: Animals; Cats; Chlorpromazine; Curare; Meprobamate; Muscle Spindles; Perfusion; Sensory Receptor Cel

1966
Role of 5-HT in the action of some drugs affecting extrapyramidal system.
    Pharmacology, 1973, Volume: 10, Issue:6

    Topics: Amphetamine; Animals; Brain; Catalepsy; Chlorpromazine; Electrodes; Extrapyramidal Tracts; Female; F

1973
Interaction of oxotremorine with atropine, chlorpromazine, cyproheptadine, imipramine and phenoxybenzamine on the flexor reflex of the chronic spinal dog.
    Psychopharmacologia, 1973, Volume: 30, Issue:1

    Topics: Animals; Atropine; Chlorpromazine; Cyproheptadine; Dogs; Drug Interactions; Imipramine; Oxotremorine

1973
Antagonism of intracaudate carbachol tremor by local injections of catecholamines.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 155, Issue:3

    Topics: Adenosine Triphosphate; Animals; Brain; Carbachol; Cats; Chlorpromazine; Dopamine; Electrophysiology

1967
Psychopharmacological effects of thiothixene and related compounds.
    Psychopharmacologia, 1968, Volume: 12, Issue:2

    Topics: Animals; Apomorphine; Avoidance Learning; Body Temperature; Catalepsy; Chlorpromazine; Dextroampheta

1968
Motor disturbance induced by tremorine and oxotremorine.
    Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1970, Volume: 267, Issue:1

    Topics: Acetylcholine; Amines; Animals; Atropine; Biperiden; Brain; Bridged-Ring Compounds; Chlorpromazine;

1970
[The emetic action of theophylline in the dog].
    Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 212, Issue:1

    Topics: Animals; Chlorpromazine; Dogs; Dose-Response Relationship, Drug; Emetics; Haloperidol; Myotonia; Nau

1974
Modification of the tremorigenic activity of physostigmine.
    British journal of pharmacology, 1972, Volume: 46, Issue:2

    Topics: Animals; Behavior, Animal; Catecholamines; Chlorpromazine; Dihydroxyphenylalanine; Drug Synergism; M

1972
L-DOPA-chlorpromazine antagonism on running activity in mice.
    Canadian journal of physiology and pharmacology, 1974, Volume: 52, Issue:1

    Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Body Weight; Chlorpromazine; Dih

1974
[The effects of sulpiride on the central nervous system].
    Pathologie-biologie, 1969, Volume: 17, Issue:1

    Topics: Amphetamine; Analgesia; Animals; Atropine; Chlorpromazine; Male; Mescaline; Mice; Morphine; Nicotine

1969
Evaluation of anti-tremor drugs in tremor-induced rodents.
    Archives internationales de pharmacodynamie et de therapie, 1965, Volume: 155, Issue:1

    Topics: 5-Hydroxytryptophan; Alkaloids; Amino Alcohols; Animals; Anticonvulsants; Chlorisondamine; Chlorprom

1965
Psychoactive agents in dogs with bilateral lesions in subcortical structures.
    Neurology, 1971, Volume: 21, Issue:8

    Topics: 5-Hydroxytryptophan; Animals; Caudate Nucleus; Chlorpromazine; Dogs; Dopamine; Haloperidol; Hippocam

1971
[A chronic extrapyramidal syndrome as a complication of neuroleptic therapy].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1969, Volume: 69, Issue:12

    Topics: Aged; Bipolar Disorder; Chlorpromazine; Chronic Disease; Extrapyramidal Tracts; Female; Haloperidol;

1969
Effects of hallucinogenic and other drugs on the nest-building behaviour of mice.
    Nature, 1970, Mar-28, Volume: 225, Issue:5239

    Topics: Animals; Chlordiazepoxide; Chlorpromazine; Competitive Behavior; Depression, Chemical; Desipramine;

1970
Blockade of norepinephrine uptake and related activities of cis- and trans-N,N'-bis-(1-naphthylmethyl)-1,4-cyclohexane bis-(methylamine) dihydrochloride.
    Biochemical pharmacology, 1970, Volume: 19, Issue:5

    Topics: Adipose Tissue; Amines; Animals; Atropine; Chlorpromazine; Cyclohexanes; Desipramine; Drug Antagonis

1970
Mesoridazine (Serentil).
    The Medical letter on drugs and therapeutics, 1971, Jan-08, Volume: 13, Issue:1

    Topics: Alcoholism; Anxiety; Brain Damage, Chronic; Chlorpromazine; Humans; Hypotension; Intellectual Disabi

1971
[Contribution on the effect of histamine on the central nervous system].
    Wiener klinische Wochenschrift, 1968, Mar-08, Volume: 80, Issue:10

    Topics: Acetylcholine; Animals; Brain Chemistry; Central Nervous System; Chlorpromazine; Drug Synergism; Fem

1968
[On the clinical picture of current forms of epidemic encephalitis].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1968, Volume: 68, Issue:3

    Topics: Adolescent; Adult; Autonomic Nervous System; Child; Chlorpromazine; Depersonalization; Encephalitis,

1968
Fate and metabolism of some hallucinogenic indolealkylamines.
    Advances in pharmacology, 1968, Volume: 6, Issue:Pt B

    Topics: Animals; Atropine; Carbon Isotopes; Chlorpromazine; Chromatography, Gas; Conditioning, Classical; Ha

1968
[On the pharmacology of active materials from betel. 2. Transformation of arecoline to arecaidine].
    Arzneimittel-Forschung, 1968, Volume: 18, Issue:2

    Topics: Animals; Areca; Behavior, Animal; Brain; Calcium; Chlorpromazine; Chromatography, Thin Layer; Guinea

1968
A comparison of three approaches to alcohol-withdrawal states.
    Southern medical journal, 1969, Volume: 62, Issue:4

    Topics: Adult; Alcoholism; Chloral Hydrate; Chlordiazepoxide; Chlorpromazine; Female; Humans; Male; Paraldeh

1969
[Contribution to the function of histamine in the central nervous system].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1969, Volume: 263, Issue:1

    Topics: Animals; Central Nervous System; Chlorpromazine; Copper; Histamine; Histidine; Lysergic Acid Diethyl

1969
Interaction of asarone with mescaline, amphetamine and tremorine.
    Life sciences, 1965, Volume: 4, Issue:17

    Topics: Animals; Atropine; Chlorpromazine; Dextroamphetamine; Hallucinations; Humans; Mescaline; Mice; Oils,

1965
[On the antagonistic effect of pyrone compounds of the kava rhizome (Piper methysticum Forst) against 1,4-dipyrrolidino-2-butyne].
    Arzneimittel-Forschung, 1965, Volume: 15, Issue:11

    Topics: Alkynes; Animals; Atropine; Chlorpromazine; Drug Antagonism; Drug Synergism; Hypothermia; Male; Mice

1965