chlorpromazine has been researched along with Torsade de Pointes in 5 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A case is presented of Torsade de Pointes (TDP) with T wave alternans in a 31-year-old female receiving a moderate dose of chlorpromazine." | 7.68 | [Torsade de Pointes with T wave alternans in a patient receiving moderate dose of chlorpromazine: report of a case]. ( Ishikawa, T; Kashiwagi, M; Ochiai, H; Oyama, Y; Tokita, Y; Usui, T, 1990) |
| "A case is presented of Torsade de Pointes (TDP) with T wave alternans in a 31-year-old female receiving a moderate dose of chlorpromazine." | 3.68 | [Torsade de Pointes with T wave alternans in a patient receiving moderate dose of chlorpromazine: report of a case]. ( Ishikawa, T; Kashiwagi, M; Ochiai, H; Oyama, Y; Tokita, Y; Usui, T, 1990) |
| " The atypicals cause fewer extrapyramidal symptoms and tardive dyskinesia, but there is growing concern regarding the significant long-term metabolic and cardiac adverse effects of these novel antipsychotics." | 2.42 | From chlorpromazine to clozapine--antipsychotic adverse effects and the clinician's dilemma. ( Abidi, S; Bhaskara, SM, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mirams, GR | 1 |
| Cui, Y | 1 |
| Sher, A | 1 |
| Fink, M | 1 |
| Cooper, J | 1 |
| Heath, BM | 1 |
| McMahon, NC | 1 |
| Gavaghan, DJ | 1 |
| Noble, D | 1 |
| Kramer, J | 1 |
| Obejero-Paz, CA | 1 |
| Myatt, G | 1 |
| Kuryshev, YA | 1 |
| Bruening-Wright, A | 1 |
| Verducci, JS | 1 |
| Brown, AM | 1 |
| Abidi, S | 1 |
| Bhaskara, SM | 1 |
| Hoehns, JD | 1 |
| Stanford, RH | 1 |
| Geraets, DR | 1 |
| Skelly, KS | 1 |
| Lee, HC | 1 |
| Gaul, BL | 1 |
| Ochiai, H | 1 |
| Kashiwagi, M | 1 |
| Usui, T | 1 |
| Oyama, Y | 1 |
| Tokita, Y | 1 |
| Ishikawa, T | 1 |
2 reviews available for chlorpromazine and Torsade de Pointes
| Article | Year |
|---|---|
From chlorpromazine to clozapine--antipsychotic adverse effects and the clinician's dilemma.
Topics: Antipsychotic Agents; Chlorpromazine; Clozapine; Diabetes Mellitus; Humans; Hyperlipidemias; Long QT | 2003 |
Torsades de pointes associated with chlorpromazine: case report and review of associated ventricular arrhythmias.
Topics: Antipsychotic Agents; Chlorpromazine; Humans; Male; Middle Aged; Torsades de Pointes; Ventricular Fi | 2001 |
3 other studies available for chlorpromazine and Torsade de Pointes
| Article | Year |
|---|---|
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; | 2011 |
MICE models: superior to the HERG model in predicting Torsade de Pointes.
Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp T | 2013 |
[Torsade de Pointes with T wave alternans in a patient receiving moderate dose of chlorpromazine: report of a case].
Topics: Adult; Chlorpromazine; Electrocardiography; Female; Humans; Schizophrenia; Syncope; Torsades de Poin | 1990 |