Page last updated: 2024-10-25

chlorpromazine and Tension-Type Headache

chlorpromazine has been researched along with Tension-Type Headache in 5 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Tension-Type Headache: A common primary headache disorder, characterized by a dull, non-pulsatile, diffuse, band-like (or vice-like) PAIN of mild to moderate intensity in the HEAD; SCALP; or NECK. The subtypes are classified by frequency and severity of symptoms. There is no clear cause even though it has been associated with MUSCLE CONTRACTION and stress. (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)

Research Excerpts

ExcerptRelevanceReference
"There were reductions in the recurrence and in the use of rescue medication in the chlorpromazine group."6.70Intravenous chlorpromazine in the acute treatment of episodic tension-type headache: a randomized, placebo controlled, double-blind study. ( Bigal, ME; Bordini, CA; Speciali, JG, 2002)
"There were reductions in the recurrence and in the use of rescue medication in the chlorpromazine group."2.70Intravenous chlorpromazine in the acute treatment of episodic tension-type headache: a randomized, placebo controlled, double-blind study. ( Bigal, ME; Bordini, CA; Speciali, JG, 2002)
"In 1996, 1254 patients were treated for headache and 64 of them required hospitalization."1.30[Headache treatment in an emergency unit of the city of Ribeirão Preto, Brazil]. ( Bigal, ME; Bordini, CA; Speciali, JG, 1999)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Weinman, D2
Nicastro, O2
Akala, O2
Friedman, BW2
Tfelt-Hansen, P1
Langemark, M1
Bigal, ME2
Bordini, CA2
Speciali, JG2

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Repurposing of Chlorpromazine in Covid-19 Treatment[NCT04366739]Phase 340 participants (Anticipated)Interventional2020-04-29Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for chlorpromazine and Tension-Type Headache

ArticleYear
Parenteral treatment of episodic tension-type headache: a systematic review.
    Headache, 2014, Volume: 54, Issue:2

    Topics: Administration, Intravenous; Chlorpromazine; Dipyrone; Humans; Injections, Intramuscular; Injections

2014

Trials

1 trial available for chlorpromazine and Tension-Type Headache

ArticleYear
Intravenous chlorpromazine in the acute treatment of episodic tension-type headache: a randomized, placebo controlled, double-blind study.
    Arquivos de neuro-psiquiatria, 2002, Volume: 60, Issue:3-A

    Topics: Acute Disease; Adult; Chlorpromazine; Dopamine Antagonists; Double-Blind Method; Female; Humans; Inj

2002

Other Studies

3 other studies available for chlorpromazine and Tension-Type Headache

ArticleYear
Parenteral treatment of episodic tension-type headache. Is there sufficient evidence?
    Headache, 2014, Volume: 54, Issue:5

    Topics: Chlorpromazine; Dipyrone; Humans; Metoclopramide; Tension-Type Headache

2014
Parenteral treatment of episodic tension-type headache: is there sufficient evidence? A response.
    Headache, 2014, Volume: 54, Issue:5

    Topics: Chlorpromazine; Dipyrone; Humans; Metoclopramide; Tension-Type Headache

2014
[Headache treatment in an emergency unit of the city of Ribeirão Preto, Brazil].
    Arquivos de neuro-psiquiatria, 1999, Volume: 57, Issue:3B

    Topics: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroida

1999