chlorpromazine has been researched along with Substance Withdrawal Syndrome in 130 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Substance Withdrawal Syndrome: Physiological and psychological symptoms associated with withdrawal from the use of a drug after prolonged administration or habituation. The concept includes withdrawal from smoking or drinking, as well as withdrawal from an administered drug.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To compare the duration of treatment for neonatal abstinence syndrome (NAS) using chlorpromazine versus morphine hydrochloride." | 7.74 | Comparison of chlorpromazine versus morphine hydrochloride for treatment of neonatal abstinence syndrome. ( Barbotte, E; Cambonie, G; Grare, A; Mazurier, E; Picaud, JC; Pinzani, V, 2008) |
| " We have pursued evidence for the existence and nature of discontinuation syndromes following neuroleptics through reports of difficulties following the use of dopamine blocking anti-emetics, the use of chlorpromazine to treat tuberculosis, the use of antidepressant-neuroleptic combinations in affective disorders, the occurrence of tardive syndromes and studies designed to establish the existence of discontinuation syndromes in schizophrenia." | 4.80 | Neuroleptic discontinuation syndromes. ( Healy, D; Tranter, R, 1998) |
| "To compare the duration of treatment for neonatal abstinence syndrome (NAS) using chlorpromazine versus morphine hydrochloride." | 3.74 | Comparison of chlorpromazine versus morphine hydrochloride for treatment of neonatal abstinence syndrome. ( Barbotte, E; Cambonie, G; Grare, A; Mazurier, E; Picaud, JC; Pinzani, V, 2008) |
| "Phenazepam given to rats in a daily dose of 2 mg/kg intraperitoneally for a long (30 days) time ceased to produce the sedative effect, and discontinuation of the medication led to development of the so-called "recoil syndrome" characterized by general depression and disturbances of the conditioned-reflex activity." | 3.66 | [Experimental study of the "'rebound syndrome" following discontinuation of prolonged phenazepam administration and possibilities for preventing it]. ( Garibova, TL; Voronina, TA, 1981) |
| "The authors studied basal HGH levels and HGH response to insulin-induced hypoglycemia in 12 schizophrenic patients who had been treated with 200--450 mg/day of chlorpromazine for 6 months to 4 years compared with 12 schizophrenic patients who had received no drugs and 15 normal control subjects." | 3.66 | Effect of chlorpromazine on human growth hormone. ( Beg, AA; Dash, RJ; Varma, VK, 1979) |
| " The dosing of various drugs currently in use is also discussed." | 2.37 | The neonatal narcotic abstinence syndrome: a brief review. ( Calabrese, JR; Gulledge, AD, 1985) |
| "Development of neuroleptic malignant syndrome (NMS) following discontinuation of high-dose and high-potency neuroleptic agents is described." | 1.28 | Neuroleptic malignant syndrome during abrupt reduction of neuroleptic treatment. ( Hermesh, H; Munitz, H; Spivak, B; Tyano, S; Weizman, A; Wolovick, L, 1990) |
| "Of these patients, 85% experienced withdrawal symptoms, mainly insomnia, anxiety, and tensional restlessness." | 1.27 | Withdrawal symptoms after long-term treatment with low-potency neuroleptics. ( Annable, L; Bradwejn, J; Chouinard, G; Jones, BD; Ross-Chouinard, A, 1984) |
| "Rats with ablated frontal sensorimotor cortex and one with ablated sensorimotor connections to forebrain showed more vacuous chewing movements following 6-week chronic administration of a neuroleptic than did occipitally damaged rats or normal controls who were treated in the same way." | 1.26 | Oral dyskinesia in brain-damaged rats withdrawn from a neuroleptic: implication for models of tardive dyskinesia. ( Glassman, HN; Glassman, RB, 1980) |
| " The controls were comprised of naive rats (G-VI) and naive rats dosed in the same manner as the dependent rats." | 1.26 | Participant of serotonin turnover rate in the brain on barbital withdrawal convulsion. ( Hiramori, T; Nakao, K; Tagashira, E; Urano, T; Yanaura, S, 1982) |
| "This suggests that symptoms of Gilles de la Tourette syndrome which appear after withdrawal of chronic neuroleptic therapy may be due to transient hypersensitivity of dopamine receptor sites." | 1.26 | Transient Gilles de la Tourette syndrome after chronic neuroleptic withdrawal. ( Singer, WD, 1981) |
| "The chronic administration of phenothiazines has come under increasing scrutiny recently, and the uncritical use of this form of treatment has been criticized." | 1.26 | Schizophrenia following withdrawal from chronic phenothiazine administration: a case report. ( Sale, I, 1978) |
| "The chronic administration of several psychoactive drugs has been suggested to produce behavioral withdrawal syndromes in the absence of physical withdrawal." | 1.26 | Behavioral withdrawal following several psychoactive drugs. ( Annau, Z; Simpson, DM, 1977) |
| "6 Animals withdrawn following chronic administration of a number of drugs, barbitone, barbitone/bemegride mixture, Mandrax (methaqualone: diphenhydramine; 10: 1), chlordiazepoxide, nitrazepam, chlorpromazine or ethanol, exhibited a significant tolerance to intracerebroventricularly administered pentobarbitone." | 1.25 | A study of the factors affecting the sleeping time following intracerebroventricular administration of pentobarbitone sodium: effect of prior administration of centrally active drugs. ( Stevenson, IH; Turnbull, MJ, 1974) |
| "Thioridazine has little antiemetic action but perphenazine is prescribed for vomiting; hence it seems unlikely that the reported symptoms are due to a rebound action on the vomiting centre." | 1.24 | GASTROINTESTINAL DISTURBANCES ASSOCIATED WITH WITHDRAWAL OF ATARACTIC DRUGS. ( HADEN, P, 1964) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 116 (89.23) | 18.7374 |
| 1990's | 9 (6.92) | 18.2507 |
| 2000's | 4 (3.08) | 29.6817 |
| 2010's | 1 (0.77) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mazurier, E | 1 |
| Cambonie, G | 1 |
| Barbotte, E | 1 |
| Grare, A | 1 |
| Pinzani, V | 1 |
| Picaud, JC | 1 |
| Kashyap, GL | 1 |
| Patel, AG | 1 |
| Scarr, E | 1 |
| Parkin, FM | 1 |
| Pavey, G | 1 |
| Dean, B | 1 |
| FOX, V | 1 |
| CAFFEY, EM | 2 |
| DIAMOND, LS | 1 |
| FRANK, TV | 1 |
| GRASBERGER, JC | 1 |
| HERMAN, L | 1 |
| KLETT, CJ | 3 |
| ROTHSTEIN, C | 1 |
| BERLE, BB | 1 |
| NYSWANDER, M | 1 |
| AYCRIGG, JB | 1 |
| THOMPSON, BA | 1 |
| HADEN, P | 1 |
| MOYNIHAN, NH | 1 |
| BARTEN, HH | 1 |
| GANTZ, RS | 1 |
| BIRKETT, DP | 1 |
| LUTZ, EG | 1 |
| CIANI, N | 1 |
| DONINI, G | 1 |
| BROOKS, W | 1 |
| DEUTSCH, L | 1 |
| DICKES, R | 1 |
| Kulkarni, J | 1 |
| McCauley-Elsom, K | 1 |
| Marston, N | 1 |
| Gilbert, H | 1 |
| Gurvich, C | 1 |
| de Castella, A | 1 |
| Fitzgerald, P | 1 |
| Nichols, MM | 2 |
| Glassman, RB | 2 |
| Glassman, HN | 2 |
| Chouinard, G | 1 |
| Bradwejn, J | 1 |
| Annable, L | 1 |
| Jones, BD | 1 |
| Ross-Chouinard, A | 1 |
| Tagashira, E | 1 |
| Hiramori, T | 1 |
| Urano, T | 1 |
| Nakao, K | 1 |
| Yanaura, S | 1 |
| Baltrus, BM | 1 |
| Feigenbaum, JJ | 1 |
| Yanai, J | 1 |
| Hershey, LA | 1 |
| Gift, T | 1 |
| Atkins, RW | 1 |
| Rivera-Calimlim, L | 1 |
| Singer, WD | 1 |
| Mueller, J | 1 |
| Aminoff, MJ | 1 |
| Uhde, TW | 1 |
| Redmond, DE | 1 |
| Kleber, HD | 1 |
| Voronina, TA | 1 |
| Garibova, TL | 1 |
| Inoue, F | 1 |
| Janikowski, AM | 1 |
| Gruzelier, JH | 1 |
| Hammond, NV | 1 |
| Evans, EB | 1 |
| Balster, RL | 1 |
| Lamb, RJ | 1 |
| Griffiths, RR | 1 |
| Sun, SF | 1 |
| Tranter, R | 1 |
| Healy, D | 1 |
| Obuchowicz, E | 1 |
| Turchan, J | 1 |
| Iqbal, N | 1 |
| Davis, JM | 1 |
| Gosenfeld, L | 1 |
| Tsai, CC | 1 |
| Belknap, JK | 1 |
| Baldino, F | 1 |
| Cowan, A | 1 |
| Geller, EB | 1 |
| Adler, MW | 1 |
| Pakes, GE | 1 |
| Neumann, LL | 2 |
| Cohen, SN | 1 |
| Rifkin, A | 1 |
| Quitkin, F | 1 |
| Kane, J | 1 |
| Struve, F | 1 |
| Klein, DF | 1 |
| Kissin, B | 1 |
| Sale, I | 1 |
| Simpson, DM | 1 |
| Annau, Z | 1 |
| Martin, BR | 1 |
| Dewey, WL | 1 |
| Chau-Pham, T | 1 |
| Prnage, AJ | 1 |
| Beg, AA | 1 |
| Varma, VK | 1 |
| Dash, RJ | 1 |
| Marholin, D | 1 |
| Touchette, PE | 1 |
| Stewart, RM | 1 |
| Symes, AL | 1 |
| Lal, S | 1 |
| Young, SN | 1 |
| Tsang, D | 1 |
| Sourkes, TL | 1 |
| Murano, T | 1 |
| Senda, H | 1 |
| Yamamoto, H | 1 |
| Yano, I | 1 |
| Lynch, MA | 1 |
| Leonard, BE | 1 |
| Lucot, JB | 1 |
| McMillan, DE | 2 |
| Leander, JD | 1 |
| Andrews, P | 1 |
| Hall, JN | 1 |
| Snaith, RP | 1 |
| Caroli, F | 1 |
| Littre-Poirier, MF | 1 |
| Ginestet, D | 1 |
| Deniker, P | 1 |
| Toone, BK | 1 |
| Fenton, GW | 1 |
| Alpert, M | 1 |
| Diamond, F | 1 |
| Laski, EM | 1 |
| Hogarty, GE | 1 |
| Ulrich, RF | 1 |
| Mussare, F | 1 |
| Aristigueta, N | 1 |
| Frederickson, RC | 1 |
| Hewes, CR | 1 |
| Aiken, JW | 1 |
| Sardemann, H | 1 |
| Friis-Hansen, B | 1 |
| Zelson, C | 5 |
| Vargas, GC | 1 |
| Pildes, RS | 1 |
| Vidyasagar, D | 1 |
| Keith, LG | 1 |
| Sayers, AC | 1 |
| Bürki, HR | 1 |
| Ruch, W | 1 |
| Asper, H | 1 |
| Gregory, RP | 1 |
| Smith, PT | 1 |
| Rudge, P | 1 |
| Spivak, B | 1 |
| Weizman, A | 1 |
| Wolovick, L | 1 |
| Hermesh, H | 1 |
| Tyano, S | 1 |
| Munitz, H | 1 |
| Matthews, P | 1 |
| Quinn, D | 1 |
| Marcoux, GS | 1 |
| Falkenberg, K | 1 |
| Koyuncuoğlu, H | 2 |
| Saydam, B | 1 |
| Dufresne, RL | 1 |
| Wagner, RL | 1 |
| Gupta, AK | 1 |
| Jha, BK | 1 |
| Kishnir, SL | 1 |
| Borisenko, SA | 1 |
| Burov, IuV | 1 |
| Sener, AI | 1 |
| Ceylan, ME | 1 |
| Calabrese, JR | 1 |
| Gulledge, AD | 1 |
| Ramkumar, V | 1 |
| el-Fakahany, EE | 1 |
| Priestley, BL | 2 |
| Tobias, LL | 1 |
| MacDonald, ML | 1 |
| Kaim, SC | 4 |
| Cicero, TJ | 1 |
| Meyer, ER | 1 |
| Bell, RD | 1 |
| Stevenson, IH | 1 |
| Turnbull, MJ | 1 |
| Avrutskii, GIa | 1 |
| Gurovich, IIa | 1 |
| Prokhorova, IS | 1 |
| Tirkel'taub, IuA | 1 |
| Romanov, IuD | 1 |
| Evans, JI | 2 |
| Lewis, SA | 3 |
| James, IP | 1 |
| Jus, A | 1 |
| Pineau, R | 1 |
| Jus, K | 1 |
| Villeneuve, A | 1 |
| Gautier, J | 1 |
| Pires, P | 1 |
| Drolet, A | 1 |
| Cote, M | 1 |
| Villeneuve, R | 1 |
| Goetz, RL | 1 |
| Bain, RV | 1 |
| McNichol, RW | 1 |
| Cirksena, WJ | 1 |
| Payne, JT | 1 |
| Glasgow, MC | 1 |
| Norton, PR | 1 |
| Oge, V | 1 |
| Mellor, CS | 1 |
| Aherwadkar, SJ | 1 |
| Efendigil, MC | 1 |
| Coulshed, N | 1 |
| Perlmutter, JF | 1 |
| Goldstein, DB | 1 |
| Kamei, C | 1 |
| Shimomura, K | 1 |
| Ueki, S | 1 |
| McClelland, HA | 1 |
| Blessed, G | 1 |
| Bhate, S | 1 |
| Ali, N | 1 |
| Clarke, PA | 1 |
| Fraser, HF | 1 |
| Lewis, BW | 1 |
| Stothers, JK | 1 |
| De Maio, D | 1 |
| Frost, JB | 1 |
| Lee, SJ | 1 |
| Casalino, M | 1 |
| Kaneto, H | 1 |
| Koida, M | 1 |
| Tsuchie, F | 1 |
| Miyagawa, H | 1 |
| Rothstein, P | 1 |
| Gould, JB | 1 |
| Zavell, PM | 1 |
| Semmens, JM | 1 |
| Hughes, JS | 1 |
| Little, JC | 1 |
| Goldberg, SC | 1 |
| Schooler, NR | 1 |
| Mattsson, N | 1 |
| Morton, MR | 1 |
| Motto, JA | 1 |
| Rothfeld, B | 1 |
| Kornetsky, C | 1 |
| Hollister, LE | 1 |
| Crane, GE | 1 |
| Naranjo, ER | 1 |
| Krystof, J | 1 |
| Zyg, J | 1 |
| Mitkiewicz, S | 1 |
| Kaczyński, J | 1 |
| Learoyd, BM | 1 |
| Barron, CN | 1 |
| Rubin, LF | 1 |
| Steelman, RL | 1 |
| Cameron, OG | 1 |
| Appel, JB | 1 |
| French, SW | 1 |
| Todoroff, T | 1 |
| Norum, ML | 1 |
| Glass, L | 1 |
| Evans, HE | 1 |
| Kahn, EJ | 2 |
| Neumann, L | 1 |
| Polk, G | 1 |
| Rubio, E | 1 |
| Wasserman, E | 1 |
| Muller, DJ | 1 |
| Kennedy, PF | 1 |
| Abenson, MH | 1 |
| Polk, GA | 1 |
| Prien, RF | 1 |
| Cole, JO | 1 |
| Belkin, NF | 1 |
| Greenberg, LM | 1 |
| Roth, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phenobarbital Versus Ativan for Refractory Alcohol Withdrawal Treatment in the Intensive Care Unit[NCT04156464] | Phase 4 | 142 participants (Anticipated) | Interventional | 2020-07-06 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 reviews available for chlorpromazine and Substance Withdrawal Syndrome
| Article | Year |
|---|---|
Evidence for the involvement of central dopaminergic receptors in the acute and chronic effects induced by barbiturates.
Topics: Adenylyl Cyclases; Animals; Barbiturates; Brain; Chlorpromazine; Dopamine; Drug Interactions; Drug T | 1983 |
Neuroleptic discontinuation syndromes.
Topics: Antiemetics; Antipsychotic Agents; Chlorpromazine; Dyskinesia, Drug-Induced; Humans; Mood Disorders; | 1998 |
Maintenance antipsychotic drugs do prevent relapse: a reply to Tobias and MacDonald.
Topics: Antipsychotic Agents; Chlorpromazine; Chronic Disease; Drug Evaluation; Fluphenazine; Humans; Perphe | 1976 |
The neonatal narcotic withdrawal syndrome: a therapeutic challenge.
Topics: Barbiturates; Chlorpromazine; Diazepam; Humans; Infant Care; Infant, Newborn; Infant, Newborn, Disea | 1975 |
The neonatal narcotic abstinence syndrome: a brief review.
Topics: Chlorpromazine; Diazepam; Female; Humans; Infant, Newborn; Methadone; Narcotics; Opium; Phenobarbita | 1985 |
Withdrawal of maintenance drugs with long-term hospitalized mental patients: a critical review.
Topics: Acute Disease; Adult; Aged; Antipsychotic Agents; Chlorpromazine; Chronic Disease; Clinical Trials a | 1974 |
Certain theoretical and practical considerations involved in evaluating the overall abuse potential of opiate agonists and antagonists.
Topics: Animals; Chlorpromazine; Codeine; Cyclazocine; Drug Combinations; Drug Evaluation; Drug Evaluation, | 1973 |
Effects of narcotics and narcotic antagonists on operant behavior.
Topics: Animals; Avoidance Learning; Behavior, Animal; Chlorpromazine; Columbidae; Conditioning, Operant; Cy | 1973 |
Psychoactive drugs in the immature organism.
Topics: Amphetamine; Animals; Autistic Disorder; Behavior, Animal; Catecholamines; Child; Child Behavior; Ch | 1970 |
23 trials available for chlorpromazine and Substance Withdrawal Syndrome
| Article | Year |
|---|---|
Lateralized deficits and drug influences on the dichotic listening of schizophrenic patients.
Topics: Attention; Chlorpromazine; Dominance, Cerebral; Galvanic Skin Response; Humans; Mental Recall; Schiz | 1980 |
Are prophylactic antiparkinson drugs necessary? A controlled study of procyclidine withdrawal.
Topics: Adult; Aftercare; Bipolar Disorder; Chlorpromazine; Clinical Trials as Topic; Double-Blind Method; D | 1978 |
Withdrawal of chronic chlorpromazine medication: an experimental analysis.
Topics: Adult; Chlorpromazine; Double-Blind Method; Humans; Intellectual Disability; Male; Middle Aged; Plac | 1979 |
A controlled trial of phenothiazine withdrawal in chronic schizophrenic patients.
Topics: Administration, Oral; Chlorpromazine; Chronic Disease; Clinical Trials as Topic; Dose-Response Relat | 1976 |
[Trial of interruption of antiparkinson drugs in long term treatments with neuroleptics].
Topics: Adult; Antiparkinson Agents; Basal Ganglia Diseases; Chlorpromazine; Clinical Trials as Topic; Fluph | 1975 |
The treatment of heroin addicts with dextromethorphan: a double-blind comparison of dextromethorphan with chlorpromazine.
Topics: Adult; Chlorpromazine; Dextromethorphan; Diazepam; Double-Blind Method; Female; Heroin Dependence; H | 1990 |
Clonidine in heroin withdrawal syndrome: a controlled study in India.
Topics: Adolescent; Adult; Chlordiazepoxide; Chlorpromazine; Clinical Trials as Topic; Clonidine; Drug Thera | 1988 |
Comparison of the suppressive effects of L-aspartic acid and chlorpromazine + diazepam treatments on opiate abstinence syndrome signs in men.
Topics: Aspartic Acid; Chlorpromazine; Diazepam; Drug Therapy, Combination; Humans; Male; Opioid-Related Dis | 1986 |
Withdrawal of maintenance drugs with long-term hospitalized mental patients: a critical review.
Topics: Acute Disease; Adult; Aged; Antipsychotic Agents; Chlorpromazine; Chronic Disease; Clinical Trials a | 1974 |
Prevention of delirium tremens: use of phenothiazines versus drugs cross-dependent with alcohol.
Topics: Antipsychotic Agents; Biogenic Amines; Brain Chemistry; Chlordiazepoxide; Chlorpromazine; Drug Toler | 1974 |
Penfluridol: a long-acting oral neuroleptic as therapeutic agent in chronic schizophrenia.
Topics: Adult; Analysis of Variance; Basal Ganglia Diseases; Body Weight; Chlorpromazine; Chronic Disease; C | 1974 |
The abrupt withdrawal of antiparkinsonian drugs in schizophrenic patients.
Topics: Adult; Aged; Antiparkinson Agents; Basal Ganglia Diseases; Behavior; Chlorpromazine; Clinical Trials | 1974 |
An appraisal of the continuing practice of prescribing tranquillizing drugs for long-stay psychiatric patients.
Topics: Chlorpromazine; Chronic Disease; Clinical Trials as Topic; Humans; Mental Disorders; Placebos; Subst | 1967 |
Paranoid and withdrawal symptoms in schizophrenia: differential symptom reduction over time.
Topics: Chlorpromazine; Clinical Trials as Topic; Fluphenazine; Humans; Paranoid Disorders; Phenothiazines; | 1967 |
A study of the withdrawal of chlorpromazine or trifluoperazine in chronic schizophrenia.
Topics: Chlorpromazine; Chronic Disease; Clinical Trials as Topic; Hospitalization; Hospitals, Psychiatric; | 1968 |
Acute alcohol-withdrawal syndromes; a controlled study of phenothiazine effectiveness.
Topics: Adult; Aged; Chlorpromazine; Clinical Trials as Topic; Emotions; Gastrointestinal Diseases; Hallucin | 1968 |
Treatment of the acute alcohol withdrawal state: a comparison of four drugs.
Topics: Chlordiazepoxide; Chlorpromazine; Clinical Trials as Topic; Humans; Hydroxyzine; Middle Aged; Placeb | 1969 |
Psychoactive drugs in the immature organism.
Topics: Amphetamine; Animals; Autistic Disorder; Behavior, Animal; Catecholamines; Child; Child Behavior; Ch | 1970 |
Evaluating changes in symptoms during acute alcohol withdrawal.
Topics: Affect; Alcoholism; Chlordiazepoxide; Chlorpromazine; Clinical Trials as Topic; Female; Humans; Hydr | 1971 |
Motor disorders induced by neuroleptics: a proposed new classification.
Topics: Adolescent; Adult; Chlorpromazine; Clinical Trials as Topic; Dystonia Musculorum Deformans; Factor A | 1971 |
The course of the heroin withdrawal syndrome in newborn infants treated with phenobarbital or chlorpromazine.
Topics: Chlorpromazine; Female; Heroin; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; Phenobarbi | 1969 |
Relapse in chronic schizophrenics following abrupt withdrawal of tranquillizing medication.
Topics: Adult; Chlorpromazine; Chronic Disease; Female; Hospitals, Psychiatric; Humans; Male; Middle Aged; P | 1969 |
Differential effects of abrupt versus gradual withdrawal of chlorpromazine in hospitalized chronic schizophrenic patients.
Topics: Chlorpromazine; Humans; Male; Placebos; Schizophrenia; Statistics as Topic; Substance Withdrawal Syn | 1966 |
100 other studies available for chlorpromazine and Substance Withdrawal Syndrome
| Article | Year |
|---|---|
Comparison of chlorpromazine versus morphine hydrochloride for treatment of neonatal abstinence syndrome.
Topics: Antiemetics; Chlorpromazine; Dopamine Antagonists; Female; Humans; Infant, Newborn; Male; Morphine; | 2008 |
Unusual presentation of a patient with GBL withdrawal: a case report.
Topics: 4-Butyrolactone; Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Chlorpromazine; Delirium; Hal | 2011 |
Decreased density of [3H]TCP binding following antipsychotic drug withdrawal in rats.
Topics: Animals; Antipsychotic Agents; Benzodiazepines; Brain; Chlorpromazine; Clozapine; Haloperidol; Ion C | 2002 |
Treatment of withdrawal symptoms in the management of alcoholism.
Topics: Alcoholism; Chlorpromazine; Humans; Muscle Relaxants, Central; Substance Withdrawal Syndrome | 1956 |
DISCONTINUATION OR REDUCTION OF CHEMOTHERAPY IN CHRONIC SCHIZOPHRENICS.
Topics: Behavior; Biomedical Research; Chlorpromazine; Humans; Placebos; Psychological Tests; Schizophrenia; | 1964 |
AMBULATORY WITHDRAWAL TREATMENT OF HEROIN ADDICTS.
Topics: Chloral Hydrate; Chlorpromazine; Drug Therapy; Glutethimide; Heroin; Humans; Meprobamate; Methylphen | 1964 |
TWO CASES OF WITHDRAWAL FROM ETHCHLORVYNOL.
Topics: Chlorpromazine; Delirium; Epilepsy, Tonic-Clonic; Ethchlorvynol; Hallucinations; Hypnotics and Sedat | 1964 |
ADDICTION TO DEXTROMORAMIDE.
Topics: Back Pain; Behavior, Addictive; Chlorpromazine; Dextromoramide; Substance Withdrawal Syndrome; Subst | 1964 |
GASTROINTESTINAL DISTURBANCES ASSOCIATED WITH WITHDRAWAL OF ATARACTIC DRUGS.
Topics: Chlorpromazine; Chlorprothixene; Drug Therapy; Gastrointestinal Diseases; Mental Disorders; Perphena | 1964 |
ALCOHOL-WITHDRAWAL SYNDROME.
Topics: Alcohol-Induced Disorders; Alcoholism; Alcohols; Chlorpromazine; Drug Therapy; Humans; Promazine; Ps | 1965 |
TOXIC PSYCHOSIS WITH TRANSIENT DYSMNESTIC SYNDROME FOLLOWING WITHDRAWAL FROM VALIUM.
Topics: Chlorpromazine; Diazepam; Epilepsy; Epilepsy, Tonic-Clonic; Hallucinations; Humans; Memory; Psychose | 1965 |
PHENOTHIAZINE REDUCTION AS A CAUSE OF REHOSPITALIZATION.
Topics: Chlorpromazine; Drug Therapy; Fluphenazine; Hospitalization; Humans; Perphenazine; Phenothiazines; P | 1965 |
DISSIPATION OF PHENOTHIAZINE EFFECT AND RECURRENCE OF SCHIZOPHRENIC PSYCHOSIS.
Topics: Chlorpromazine; Drug Therapy; Humans; Phenothiazines; Psychotic Disorders; Schizophrenia; Substance | 1965 |
[ON THERAPEUTIC EFFICACY OF SUDDEN SUSPENSION OF PROLONGED THERAPY WITH ASSOCIATED RESERPINE AND CHLORPROMAZINE IN SCHIZOPHRENIC SUBJECTS].
Topics: Chlorpromazine; Drug Therapy; Haloperidol; Humans; Phenothiazines; Reserpine; Schizophrenia; Substan | 1965 |
The use of chlorpromazine hydrochloride in the treatment of barbiturate addiction with acute withdrawal syndrome.
Topics: Barbiturates; Behavior, Addictive; Chlorpromazine; Humans; Substance Withdrawal Syndrome; Substance- | 1955 |
Preliminary findings from the National Register of Antipsychotic Medication in Pregnancy.
Topics: Adult; Antipsychotic Agents; Australia; Benzodiazepines; Chlorpromazine; Cross-Sectional Studies; Da | 2008 |
Acute alcohol withdrawal syndrome in a newborn.
Topics: Adult; Alcoholism; Chlorpromazine; Exchange Transfusion, Whole Blood; Female; Glucose; Humans; Hyper | 1967 |
Oral dyskinesia in brain-damaged rats withdrawn from a neuroleptic: implication for models of tardive dyskinesia.
Topics: Amphetamine; Animals; Antipsychotic Agents; Apomorphine; Behavior, Animal; Brain; Chlorpromazine; Di | 1980 |
Withdrawal symptoms after long-term treatment with low-potency neuroleptics.
Topics: Adult; Akathisia, Drug-Induced; Ambulatory Care; Antipsychotic Agents; Anxiety Disorders; Chlorproma | 1984 |
Participant of serotonin turnover rate in the brain on barbital withdrawal convulsion.
Topics: Animals; Barbital; Barbiturates; Brain; Chlorpromazine; Humans; Hydroxyindoleacetic Acid; Male; Nitr | 1982 |
Failure to find electrophysiological correlates of chronic neuroleptic-induced oral dyskinesias in cats: somatosensory and substantia nigra evoked potentials, electroencephalogram, and caudate spindles.
Topics: Animals; Basal Ganglia; Cats; Caudate Nucleus; Chlorpromazine; Electroencephalography; Evoked Potent | 1982 |
Effect of a drug holiday on plasma chlorpromazine levels in chronic schizophrenic patients.
Topics: Adult; Chlorpromazine; Chronic Disease; Humans; Male; Middle Aged; Parkinson Disease, Secondary; Phe | 1981 |
Transient Gilles de la Tourette syndrome after chronic neuroleptic withdrawal.
Topics: Adolescent; Chlorpromazine; Drug Hypersensitivity; Haloperidol; Humans; Male; Receptors, Dopamine; S | 1981 |
Tourette-like syndrome after long-term neuroleptic drug treatment.
Topics: Adult; Chlorpromazine; Dyskinesia, Drug-Induced; Haloperidol; Humans; Male; Substance Withdrawal Syn | 1982 |
Psychosis in the opioid addicted patient: assessment and treatment.
Topics: Adult; Chlorpromazine; Diagnosis, Differential; Double-Blind Method; Haloperidol; Heroin Dependence; | 1982 |
[Experimental study of the "'rebound syndrome" following discontinuation of prolonged phenazepam administration and possibilities for preventing it].
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Chlorpromazine; Conditioning, Clas | 1981 |
Withdrawal akinesia.
Topics: Basal Ganglia Diseases; Chlorpromazine; Humans; Male; Middle Aged; Substance Withdrawal Syndrome; Th | 1981 |
Inhaled 1,1,1-trichloroethane-produced physical dependence in mice: effects of drugs and vapors on withdrawal.
Topics: Administration, Inhalation; Animals; Chlorpromazine; Ethanol; Male; Mice; Midazolam; Pentobarbital; | 1993 |
Behavioral effects of pentobarbital, lorazepam, ethanol and chlorpromazine substitution in pentobarbital-dependent baboons.
Topics: Animals; Behavior, Animal; Chlorpromazine; Ethanol; Lorazepam; Male; Papio; Pentobarbital; Substance | 1993 |
[Nursing care of abstinent patients with heroin addiction].
Topics: Adult; Chlorpromazine; Female; Fever; Heroin; Heroin Dependence; Humans; Male; Promethazine; Substan | 1993 |
Effects of acute or long-term treatment with chlorpromazine, haloperidol or sulpiride on neuropeptide Y-like immunoreactivity concentrations in the nucleus accumbens of rat.
Topics: Animals; Antipsychotic Agents; Chlorpromazine; Dopamine Antagonists; Dopamine D2 Receptor Antagonist | 1999 |
Heroin use, diplopia, largactil.
Topics: Adult; Antipsychotic Agents; Chlorpromazine; Diplopia; Heroin; Humans; Male; Substance Withdrawal Sy | 2000 |
Barbiturate physical dependence in mice: effects of neuroleptics and diazepam on the withdrawal syndrome.
Topics: Animals; Antipsychotic Agents; Barbiturates; Chlorpromazine; Diazepam; Haloperidol; Humans; Male; Me | 1978 |
Effects of antipsychotic and antianxiety drugs on the morphine abstinence syndrome in rats.
Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Behavior, Animal; Body Weight; Chlordiazepoxide; | 1979 |
Lithium toxicity with phenothiazine withdrawal.
Topics: Chlorpromazine; Humans; Lithium; Substance Withdrawal Syndrome | 1979 |
The use of psychoactive drugs in the long-term treatment of chronic alcoholics.
Topics: Alcoholism; Anti-Anxiety Agents; Antipsychotic Agents; Anxiety; Chlordiazepoxide; Chlorpromazine; Ch | 1975 |
Schizophrenia following withdrawal from chronic phenothiazine administration: a case report.
Topics: Adult; Chlorpromazine; Female; Humans; Schizophrenia; Substance Withdrawal Syndrome | 1978 |
Behavioral withdrawal following several psychoactive drugs.
Topics: Animals; Brain; Chlorpromazine; Desipramine; Dextroamphetamine; Electric Stimulation; Humans; Iproni | 1977 |
Interactions of thyrotropin releasing hormone and morphine sulfate in rodents.
Topics: Analgesics; Animals; Apomorphine; Behavior, Animal; Body Weight; Chlorpromazine; Dronabinol; Humans; | 1977 |
Effect of chlorpromazine on human growth hormone.
Topics: Adolescent; Adult; Child; Chlorpromazine; Dose-Response Relationship, Drug; Female; Growth Hormone; | 1979 |
Effect of chronic chlorpromazine administration or prior treatment with reserpine on brain apomorphine concentrations and apomorphine-induced sterotyped behaviour in the rat.
Topics: Animals; Apomorphine; Behavior; Brain Chemistry; Chlorpromazine; Drug Interactions; Humans; Male; Mo | 1977 |
Studies on the physical dependence potential of analgesics.
Topics: Adrenal Cortex; Animals; Chlorpromazine; Humans; Levallorphan; Male; Mice; Mitochondria; Morphine; M | 1978 |
Changes in brain gamma-aminobutyric acid concentrations following acute and chronic amphetamine administration and during post amphetamine depression.
Topics: Animals; Brain; Chlorpromazine; Depression; Dextroamphetamine; gamma-Aminobutyric Acid; Humans; Male | 1978 |
The behavioral effects of chlorpromazine alone and in combination with different morphine treatments in rats.
Topics: Animals; Behavior, Animal; Chlorpromazine; Conditioning, Operant; Dose-Response Relationship, Drug; | 1979 |
Epileptic seizures induced by psychotropic drugs.
Topics: Adolescent; Adult; Aged; Birth Order; Brain Damage, Chronic; Chlorpromazine; Diazepam; Dose-Response | 1977 |
Anticholinergic exacerbation of phenothiazine-induced extrapyramidal syndrome.
Topics: Adult; Basal Ganglia Diseases; Chlorpromazine; Humans; Substance Withdrawal Syndrome; Trifluoperazin | 1976 |
Drug discontinuation among long term, successfully maintained schizophrenic outpatients.
Topics: Ambulatory Care; Chlorpromazine; Humans; Movement Disorders; Recurrence; Schizophrenia; Schizophreni | 1976 |
Correlation between the in vivo and an in vitro expression of opiate withdrawal precipitated by naloxone: their antagonism by l-(-)-delta9-tetrahydrocannabinol.
Topics: Acetylcholine; Animals; Chlorpromazine; Codeine; Dose-Response Relationship, Drug; Dronabinol; Femal | 1976 |
[New born infants of drug addicted mothers].
Topics: Adolescent; Adult; Birth Weight; Chlorpromazine; Diazepam; Female; Humans; Infant, Newborn; Infant, | 1975 |
Acute management of neonatal addiction.
Topics: Antidiarrheals; Chlorpromazine; Diazepam; Female; Heroin Dependence; Humans; Infant, Newborn; Infant | 1975 |
Effect of maternal heroin addiction on 67 liveborn neonates. Withdrawal symptoms, small body size, and small head circumference were frequent findings.
Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Birth Weight; Blood Glucose; Cephalomet | 1975 |
Neuroleptic-induced hypersensitivity of striatal dopamine receptors in the rat as a model of tardive dyskinesias. Effects of clozapine, haloperidol, loxapine and chlorpromazine.
Topics: Animals; Apomorphine; Chlorpromazine; Clozapine; Corpus Striatum; Dibenzazepines; Dibenzoxazepines; | 1975 |
Tardive dyskinesia presenting as severe dysphagia.
Topics: Bipolar Disorder; Chlorpromazine; Deglutition Disorders; Dyskinesia, Drug-Induced; Female; Flupenthi | 1992 |
Neuroleptic malignant syndrome during abrupt reduction of neuroleptic treatment.
Topics: Adolescent; Antipsychotic Agents; Chlorpromazine; Dose-Response Relationship, Drug; Drug Therapy, Co | 1990 |
Fluoxetine and neuroleptic synergistic effects.
Topics: Adolescent; Chlorpromazine; Diseases in Twins; Drug Synergism; Fluoxetine; Haloperidol; Humans; Male | 1991 |
Antipsychotic-withdrawal akathisia versus antipsychotic-induced akathisia: further evidence for the existence of tardive akathisia.
Topics: Adult; Akathisia, Drug-Induced; Ambulatory Care; Antipsychotic Agents; Basal Ganglia Diseases; Chlor | 1988 |
Hematemesis following discontinuation of psychoactive drugs in geriatric patients.
Topics: Aged; Chlorpromazine; Female; Haloperidol; Hematemesis; Humans; Imipramine; Male; Procyclidine; Psyc | 1988 |
[Effect of pharmacological substances on the altered permeability of the hemato-encephalic barrier for 14C-tyrosine due to ethanol].
Topics: Alcoholism; Animals; Blood-Brain Barrier; Carbon Radioisotopes; Cell Membrane Permeability; Chlorpro | 1987 |
Changes in the affinity of [3H]nimodipine binding sites in the brain upon chlorpromazine treatment and subsequent withdrawal.
Topics: Animals; Binding Sites; Brain; Calcium Channel Blockers; Chlorpromazine; Humans; In Vitro Techniques | 1985 |
Drug addiction and the newborn.
Topics: Amphetamine; Antipsychotic Agents; Barbiturates; Cannabis; Child Welfare; Chlorpromazine; Diazepam; | 1973 |
Effects of phenoxybenzamine on the narcotic withdrawal syndrome in the rat.
Topics: Adrenergic beta-Antagonists; Animals; Behavior, Animal; Body Weight; Chlorpromazine; Depression, Che | 1974 |
A study of the factors affecting the sleeping time following intracerebroventricular administration of pentobarbitone sodium: effect of prior administration of centrally active drugs.
Topics: Aging; Amphetamine; Animals; Anti-Anxiety Agents; Barbiturates; Body Weight; Carbon Radioisotopes; C | 1974 |
[Sudden cessation of psychotropic drugs].
Topics: Adolescent; Adult; Amitriptyline; Antidepressive Agents; Bipolar Disorder; Blood Pressure; Chlorprom | 1974 |
Sleep studies in early delirium and during drug withdrawal in normal subjects and the effect of phenothiazines on such states.
Topics: Amobarbital; Chlorpromazine; Delirium; Humans; Phenothiazines; Sleep, REM; Substance Withdrawal Synd | 1968 |
Acute phenothiazine dystonia in narcotic addicts.
Topics: Chlorpromazine; Humans; Muscular Diseases; Parasympatholytics; Substance Withdrawal Syndrome; Substa | 1969 |
Neonatal withdrawal symptoms associated with maternal use of pentazocine.
Topics: Back Pain; Camphor; Chlorpromazine; Death, Sudden; Female; Humans; Infant, Newborn; Infant, Newborn, | 1974 |
Management of withdrawal from alcohol (including delirium tremens).
Topics: Adrenocorticotropic Hormone; Alcoholism; Anti-Bacterial Agents; Chlorpromazine; Humans; Hydrocortiso | 1967 |
Drug withdrawal state. An EEG sleep study.
Topics: Amobarbital; Chlorpromazine; Electroencephalography; Humans; Male; Sleep, REM; Substance Withdrawal | 1968 |
Infant of the addicted mother.
Topics: Chlorpromazine; Diazepam; Female; Heroin Dependence; Humans; Infant, Newborn; Infant, Newborn, Disea | 1973 |
The effects of drugs on barbiturate withdrawal convulsions in the rat.
Topics: Animals; Barbiturates; Chlordiazepoxide; Chlorpromazine; Ethanol; Ethosuximide; Female; Humans; Hydr | 1970 |
Drug therapy in alcoholism. It is especially important in the prevention of such complications as seizures, DT's, Wernicke's encephalopathy, or polyneuritis.
Topics: Alcoholism; Anticonvulsants; Chlordiazepoxide; Chlorpromazine; Diazepam; Disulfiram; Humans; Hydroxy | 1971 |
Sedation threshold and sedation recovery time in alcoholics.
Topics: Adult; Alcoholism; Amobarbital; Attention; Chloral Hydrate; Chlorpromazine; Differential Threshold; | 1974 |
Chlorpromazine therapy, and associated acute disturbances of cardiac rhythm.
Topics: Adult; Blood Glucose; Chlorpromazine; Electrocardiography; Female; Haloperidol; Heart Block; Humans; | 1974 |
Heroin addiction and pregnancy.
Topics: Apgar Score; Birth Weight; Breech Presentation; Chlorpromazine; Delivery, Obstetric; Female; Fetal D | 1974 |
Quantitative study of alcohol withdrawal signs in mice.
Topics: Alcoholism; Animals; Barbiturates; Behavior, Animal; Chlorpromazine; Diazepam; Disease Models, Anima | 1973 |
Significance of withdrawal jumping response in predicting physical dependence in mice.
Topics: Amitriptyline; Animals; Atropine; Cannabis; Chlordiazepoxide; Chlorpromazine; Diazepam; Humans; Imip | 1973 |
Treatment of neonatal withdrawal syndrome.
Topics: Chlorpromazine; Diazepam; Heroin Dependence; Humans; Infant, Newborn; Methadone; Opium; Phenobarbita | 1973 |
Congenital narcotic addiction.
Topics: Chlorpromazine; Female; Humans; Infant, Newborn; Narcotics; Pregnancy; Substance Withdrawal Syndrome | 1973 |
Letter: Withdrawal syndrome after neuroleptics.
Topics: Adult; Chlorpromazine; Haloperidol; Humans; Male; Parkinson Disease, Secondary; Substance Withdrawal | 1973 |
Mesoridazine and chlorpromazine in the treatment of alcohol withdrawal syndrome.
Topics: Administration, Oral; Alcoholism; Chlorpromazine; Female; Humans; Injections, Intramuscular; Male; M | 1973 |
Neonatal narcotic addiction. Comparative effects of maternal intake of heroin and methadone.
Topics: Adult; Apgar Score; Birth Weight; Chlorpromazine; Female; Gestational Age; Heroin Dependence; Humans | 1973 |
[Screening procedure for barbital type physical dependence liability of psychotropic drugs in mice].
Topics: Amitriptyline; Animals; Barbiturates; Behavior, Animal; Benzazepines; Benzodiazepinones; Body Weight | 1973 |
Managing emergencies in the newborn.
Topics: Anesthesia, Obstetrical; Anti-Bacterial Agents; Apnea; Bronchopneumonia; Chlorpromazine; Cyclopropan | 1974 |
Born with a habit. Infants of drug-addicted mothers.
Topics: Abnormalities, Drug-Induced; Adult; Age Factors; Barbiturates; Camphor; Chlorpromazine; Codeine; Dia | 1974 |
Perinatal tips.
Topics: Chlorpromazine; Education, Medical, Continuing; Female; Humans; Infant, Newborn; Infant, Newborn, Di | 1974 |
Letter: Chlorodyne dependence.
Topics: Blood Glucose; Chloroform; Chlorpromazine; Drug Combinations; Female; Humans; Infant, Newborn; Infan | 1974 |
Withdrawal symptoms after long-term treatment with neuroleptics.
Topics: Adult; Aged; Blood Circulation; Chlorpromazine; Fever; Humans; Hyperkinesis; Hypotension; Hypothermi | 1972 |
The effect of sedatives on the metabolic rate during alcohol withdrawal.
Topics: Adult; Alcoholism; Amobarbital; Basal Metabolism; Chlormethiazole; Chlorpromazine; Depression, Chemi | 1972 |
Chlorpromazine and the eye of the dog. IV. Reversibility of ocular lesions.
Topics: Animals; Chlorpromazine; Cornea; Cytoplasmic Granules; Dogs; Eye Diseases; Female; Humans; Male; Pen | 1972 |
Conditioned suppression of bar-pressing behavior by stimuli associated with drugs.
Topics: Animals; Behavior, Animal; Chlorpromazine; Conditioning, Operant; Drinking Behavior; Extinction, Psy | 1972 |
Effect of in vivo and in vitro ethanol and chlorpromazine on brain mitochondria after ethanol withdrawal.
Topics: Animals; Brain; Calcium; Cell Fractionation; Cell Membrane Permeability; Chlorpromazine; Ethanol; Hu | 1972 |
Drug addiction and the newborn.
Topics: Birth Weight; Child Development; Child Welfare; Chlorpromazine; Heroin; Heroin Dependence; Humans; I | 1972 |
Narcotic withdrawal in the newborn.
Topics: Birth Weight; Chlorpromazine; Cocaine; Female; Heroin Dependence; Humans; Infant, Newborn; Infant, N | 1972 |
Heroin withdrawal syndrome.
Topics: Chlorpromazine; Female; Heroin; Humans; Infant, Newborn; Infant, Newborn, Diseases; Maternal-Fetal E | 1970 |
Optimal therapy of the alcohol withdrawal state.
Topics: Adult; Chlordiazepoxide; Chlorpromazine; Electrolytes; Female; Humans; Hydroxyzine; Male; Paraldehyd | 1970 |
Neonatal narcotic addiction: 10 year observation.
Topics: Birth Weight; Chlorpromazine; Congenital Abnormalities; Female; Heroin; Humans; Infant, Newborn; Jau | 1971 |
A comparison of three approaches to alcohol-withdrawal states.
Topics: Adult; Alcoholism; Chloral Hydrate; Chlordiazepoxide; Chlorpromazine; Female; Humans; Male; Paraldeh | 1969 |
Chorea and phenothiazines.
Topics: Aged; Chlorpromazine; Chorea; Female; Humans; Movement Disorders; Phenothiazines; Schizophrenia; Sub | 1969 |
Subjective estimates of sleep: an EEG evaluation.
Topics: Analysis of Variance; Chlormethiazole; Chlorpromazine; Electroencephalography; Female; Humans; Hypno | 1969 |
Drug withdrawal in male and female chronic schizophrenics.
Topics: Chlorpromazine; Chronic Disease; Cognition Disorders; Female; Humans; Male; Paranoid Disorders; Phen | 1969 |