chlorpromazine has been researched along with Stevens-Johnson Syndrome in 7 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Stevens-Johnson Syndrome: Rare cutaneous eruption characterized by extensive KERATINOCYTE apoptosis resulting in skin detachment with mucosal involvement. It is often provoked by the use of drugs (e.g., antibiotics and anticonvulsants) or associated with PNEUMONIA, MYCOPLASMA. It is considered a continuum of Toxic Epidermal Necrolysis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Six cases of drug-induced toxic epidermal necrolysis treated in a burns unit are presented." | 1.28 | Treatment of toxic epidermal necrolysis and a review of six cases. ( Krzeminska, EC; Tanner, NS; Ward, DJ, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (71.43) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| BAILEY, G | 1 |
| ROSENBAUM, JM | 1 |
| ANDERSON, B | 1 |
| Purcell, P | 1 |
| Valmana, A | 1 |
| Ward, DJ | 1 |
| Krzeminska, EC | 1 |
| Tanner, NS | 1 |
| Ohlenschlaeger, K | 1 |
| Stein, KM | 1 |
| Schlappner, OL | 1 |
| Heaton, CL | 1 |
| Decherd, JW | 1 |
| Bruinsma, W | 1 |
| Lalla, M | 1 |
| Virolainen, M | 1 |
7 other studies available for chlorpromazine and Stevens-Johnson Syndrome
| Article | Year |
|---|---|
TOXIC EPIDERMAL NECROLYSIS.
Topics: Alcoholism; Anti-Bacterial Agents; Chloramphenicol; Chlorpromazine; Drug Eruptions; Drug Therapy; Hu | 1965 |
Toxic epidermal necrolysis following chlorpromazine ingestion complicated by SIADH.
Topics: Adult; Antipsychotic Agents; Chlorpromazine; Humans; Inappropriate ADH Syndrome; Male; Stevens-Johns | 1996 |
Treatment of toxic epidermal necrolysis and a review of six cases.
Topics: Adolescent; Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Antimalarials; Chlorp | 1990 |
Toxic epidermal necrolysis and Stevens-Johnson's disease.
Topics: Adult; Blood Transfusion; Chlorpromazine; Diagnosis, Differential; Female; Humans; Immunization, Pas | 1966 |
Demonstration of basal cell immunofluorescence in drug-induced toxic epidermal necrolysis.
Topics: Adult; Binding Sites; Chlorpromazine; Complement System Proteins; Female; Fluorescent Antibody Techn | 1972 |
Adverse reaction profiles of drug eruptions.
Topics: Ampicillin; Analgesics; Aspirin; Chlorpromazine; Drug-Related Side Effects and Adverse Reactions; Er | 1972 |
Blood lymphoblast proliferation in vivo in cutaneous drug hypersensitivity reactions.
Topics: Blood Cell Count; Carbamazepine; Chlorpromazine; Drug Hypersensitivity; Exanthema; Humans; Lymphocyt | 1974 |