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chlorpromazine and Rhabdomyolysis

chlorpromazine has been researched along with Rhabdomyolysis in 4 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Rhabdomyolysis: Necrosis or disintegration of skeletal muscle often followed by myoglobinuria.

Research Excerpts

ExcerptRelevanceReference
"After receiving 90 mg of haloperidol and 100 mg of chlorpromazine hydrochloride within 25 hours, a 29-year-old man was found to have neuroleptic malignant syndrome (NMS), characterized by the acute onset of hyperpyrexia, extreme muscular rigidity, autonomic instability, and coma."3.67Neuroleptic malignant syndrome and dopaminergic blockade. ( Hashimoto, F; Jeffery, WH; Sherman, CB, 1984)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's1 (25.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Matsusue, A2
Hara, K2
Kageura, M2
Kashiwagi, M2
Lu, W2
Ishigami, A2
Gotohda, T2
Tokunaga, I2
Nisimura, A2
Sugimura, T2
Kubo, S2
Hashimoto, F1
Sherman, CB1
Jeffery, WH1
Soejima, A1
Suzuki, M1
Nagasawa, T1

Reviews

1 review available for chlorpromazine and Rhabdomyolysis

ArticleYear
[Rhabdomyolysis].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49, Issue:6

    Topics: Acute Kidney Injury; Adult; Chlorpromazine; Female; Haloperidol; Humans; Myoglobin; Myoglobinuria; R

1991

Other Studies

3 other studies available for chlorpromazine and Rhabdomyolysis

ArticleYear
Genetic analysis of ryanodine receptor 1 gene and carnitine palmitoyltransferase II gene: an autopsy case of neuroleptic malignant syndrome related to vegetamin.
    Legal medicine (Tokyo, Japan), 2009, Volume: 11 Suppl 1

    Topics: Adult; Amino Acid Substitution; Antipsychotic Agents; Brain; Brain Edema; Carnitine O-Palmitoyltrans

2009
An autopsy case of rhabdomyolysis related to vegetamin and genetic analysis of the rhabdomyolysis-associated genes.
    Journal of forensic and legal medicine, 2010, Volume: 17, Issue:1

    Topics: Adult; Amino Acid Substitution; Antipsychotic Agents; Carnitine O-Palmitoyltransferase; Chlorpromazi

2010
Neuroleptic malignant syndrome and dopaminergic blockade.
    Archives of internal medicine, 1984, Volume: 144, Issue:3

    Topics: Adult; Chlorpromazine; Dopamine; Haloperidol; Humans; Male; Muscular Diseases; Receptors, Dopamine;

1984