chlorpromazine has been researched along with Reperfusion Injury in 5 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To analyze the influence of chlorpromazine on renal histology of rats submitted to ischemia and reperfusion injury." | 7.83 | Influence of chlorpromazine on renal histology of rats submitted to ischemia and reperfusion injury. ( Brenny, T; Czeczko, NG; Foiatto, JC; Gomes, RP; Malafaia, O; Oliveira, AM; Wietzikoski, EG, 2016) |
| "In both the CPZ-treated and nontreated groups, ischemia induced a decline in muscle glycogen content, with a corresponding increase in muscle lactate and a decrease in mitochondrial respiratory control ratio." | 5.32 | Lack of chlorpromazine effect on skeletal muscle metabolism after ischemia and a short reperfusion period. ( Cherri, J; Massuda, CA; Piccinato, CE; Salles Roselino, JE, 2004) |
| "To analyze the influence of chlorpromazine on renal histology of rats submitted to ischemia and reperfusion injury." | 3.83 | Influence of chlorpromazine on renal histology of rats submitted to ischemia and reperfusion injury. ( Brenny, T; Czeczko, NG; Foiatto, JC; Gomes, RP; Malafaia, O; Oliveira, AM; Wietzikoski, EG, 2016) |
| "To evaluate the influence of chlorpromazine (CPZ) on renal function and lipid peroxidation in a rat model of kidney ischemia/reperfusion injury." | 3.74 | Renal ischemia and reperfusion injury: influence of chorpromazine on renal function and lipid peroxidation. ( Carvalho, RM; Celini, FM; Cologna, AJ; Martins, AC; Suaid, HJ; Tirapelli, LF; Tucci Junior, S, 2008) |
| "In both the CPZ-treated and nontreated groups, ischemia induced a decline in muscle glycogen content, with a corresponding increase in muscle lactate and a decrease in mitochondrial respiratory control ratio." | 1.32 | Lack of chlorpromazine effect on skeletal muscle metabolism after ischemia and a short reperfusion period. ( Cherri, J; Massuda, CA; Piccinato, CE; Salles Roselino, JE, 2004) |
| "Spinal cord ischemia was obtained by clamping the abdominal aorta caudally to the renal arteries for 30 min, after which it was released and the animals were observed for a period of 48 hrs." | 1.31 | The protective action of chlorpromazine on the spinal cord of rabbits submitted to ischemia and reperfusion is dose-dependent. ( Alves, P; Barbieri-Neto, J; Mazzetto, SA; Sader, AA; Sader, SL; Vanni, JC, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Foiatto, JC | 1 |
| Czeczko, NG | 1 |
| Wietzikoski, EG | 1 |
| Malafaia, O | 1 |
| Brenny, T | 1 |
| Oliveira, AM | 1 |
| Gomes, RP | 1 |
| Tucci Junior, S | 1 |
| Carvalho, RM | 1 |
| Celini, FM | 1 |
| Cologna, AJ | 1 |
| Suaid, HJ | 1 |
| Tirapelli, LF | 1 |
| Martins, AC | 1 |
| Sader, AA | 1 |
| Barbieri-Neto, J | 1 |
| Sader, SL | 1 |
| Mazzetto, SA | 1 |
| Alves, P | 1 |
| Vanni, JC | 1 |
| Piccinato, CE | 1 |
| Salles Roselino, JE | 1 |
| Massuda, CA | 1 |
| Cherri, J | 1 |
| Roselino, JE | 1 |
| Castro-e-Silva Júnior, O | 1 |
| Romanello, LM | 1 |
| Ceneviva, R | 1 |
5 other studies available for chlorpromazine and Reperfusion Injury
| Article | Year |
|---|---|
Influence of chlorpromazine on renal histology of rats submitted to ischemia and reperfusion injury.
Topics: Animals; Chlorpromazine; Disease Models, Animal; Ischemia; Ischemic Preconditioning; Kidney; Kidney | 2016 |
Renal ischemia and reperfusion injury: influence of chorpromazine on renal function and lipid peroxidation.
Topics: Animals; Biomarkers; Chlorpromazine; Creatinine; Disease Models, Animal; Dopamine Antagonists; Ische | 2008 |
The protective action of chlorpromazine on the spinal cord of rabbits submitted to ischemia and reperfusion is dose-dependent.
Topics: Animals; Biopsy, Needle; Brain Ischemia; Chlorpromazine; Disease Models, Animal; Dose-Response Relat | 2002 |
Lack of chlorpromazine effect on skeletal muscle metabolism after ischemia and a short reperfusion period.
Topics: Animals; Chlorpromazine; Disease Models, Animal; Dogs; Glycogen; Hydrogen-Ion Concentration; Ischemi | 2004 |
Effect of chlorpromazine and biliary drainage on portal blood flow and mitochondrial function during extrahepatic cholestasis.
Topics: Alanine Transaminase; Animals; Bile Ducts; Chlorpromazine; Cholestasis, Extrahepatic; Drainage; Hydr | 1989 |