chlorpromazine has been researched along with Puberty, Precocious in 3 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Puberty, Precocious: Development of SEXUAL MATURATION in boys and girls at a chronological age that is 2.5 standard deviations below the mean age at onset of PUBERTY in the population. This early maturation of the hypothalamic-pituitary-gonadal axis results in sexual precocity, elevated serum levels of GONADOTROPINS and GONADAL STEROID HORMONES such as ESTRADIOL and TESTOSTERONE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of chlorpromazine (CPZ) on prolactin (PRL) secretion was studied in fourteen sexually immature males; nine with idiopathic hypogonadotrophic hypogonadism and five who proved to be normal early pubertal boys." | 7.66 | The response of prolactin to chlorpromazine stimulation in men with hypogonadotrophic hypogonadism and early pubertal boys: relationship to sex steroid exposure. ( Johnsonbaugh, RE; Sherins, RJ; Winters, SJ, 1982) |
| "The effect of chlorpromazine (CPZ) on prolactin (PRL) secretion was studied in fourteen sexually immature males; nine with idiopathic hypogonadotrophic hypogonadism and five who proved to be normal early pubertal boys." | 3.66 | The response of prolactin to chlorpromazine stimulation in men with hypogonadotrophic hypogonadism and early pubertal boys: relationship to sex steroid exposure. ( Johnsonbaugh, RE; Sherins, RJ; Winters, SJ, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ismail, AA | 1 |
| Harkness, RA | 1 |
| Winters, SJ | 1 |
| Johnsonbaugh, RE | 1 |
| Sherins, RJ | 1 |
| Kurachi, K | 1 |
| Ozaki, M | 1 |
| Tani, T | 1 |
| Mitsui, I | 1 |
| Miyazaki, M | 1 |
3 other studies available for chlorpromazine and Puberty, Precocious
| Article | Year |
|---|---|
Urinary testosterone excretion in men in normal and pathological conditions.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocortical Hyperfunction; Adult; Chlorpromazine; Hum | 1967 |
The response of prolactin to chlorpromazine stimulation in men with hypogonadotrophic hypogonadism and early pubertal boys: relationship to sex steroid exposure.
Topics: Adolescent; Adult; Child; Chlorpromazine; Chorionic Gonadotropin; Follicle Stimulating Hormone; Huma | 1982 |
[Clinical picture of gonadotropin secretion anomalies].
Topics: Adult; Amenorrhea; Chiari-Frommel Syndrome; Chlorpromazine; Female; Gonadotropins; Humans; Hypopitui | 1968 |