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chlorpromazine and Psychomotor Agitation

chlorpromazine has been researched along with Psychomotor Agitation in 26 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Psychomotor Agitation: A feeling of restlessness associated with increased motor activity. This may occur as a manifestation of nervous system drug toxicity or other conditions.

Research Excerpts

ExcerptRelevanceReference
"To examine the effects of oral or intramuscular chlorpromazine for psychosis induced agitation or aggression."8.86Chlorpromazine for psychosis induced aggression or agitation. ( Adams, CE; Ahmed, U; Jones, H, 2010)
"To examine the effects of oral or intramuscular chlorpromazine for psychosis induced agitation or aggression."4.86Chlorpromazine for psychosis induced aggression or agitation. ( Adams, CE; Ahmed, U; Jones, H, 2010)
" He developed neuroleptic malignant syndrome (NMS) which was treated successfully with intravenous diazepam."3.69Catatonic syndrome following recovery from neuroleptic malignant syndrome. ( Dent, J, 1995)
"Rectal thiopental is superior to this drug combination for pediatric sedation because it can be administered painlessly, has a more rapid onset and offset of action, and is of equal safety and efficacy at the dosage studied."2.67Rectal thiopental compared with intramuscular meperidine, promethazine, and chlorpromazine for pediatric sedation. ( Carey, BE; Falk, JL; Malone, LC; O'Brien, JF, 1991)
"Symptoms and clinical presentations of OTC deficiency vary widely according to the remaining activity of the enzyme."1.51Malnutrition with hypoaminoacidemia in a 22-year-old pregnant patient masking a likely ornithine transcarbamylase deficiency. ( Chartier, M; Cynober, L; Lefrère, B; Neveux, N; Patkaï, J; Ulmann, G, 2019)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199014 (53.85)18.7374
1990's3 (11.54)18.2507
2000's1 (3.85)29.6817
2010's6 (23.08)24.3611
2020's2 (7.69)2.80

Authors

AuthorsStudies
Dib, JE1
Yaacoub, HE1
Ikdais, WH1
Atallah, E1
Merheb, TJ1
Ajaltouni, J1
Akkari, M1
Mourad, M1
Nasr, ME1
Hachem, D1
Kazour, F1
Tahan, F1
Haddad, G1
Azar, J1
Zoghbi, M1
Haddad, C1
Hallit, S1
Adams, CE3
Choi, M1
Barra, ME1
Newman, K1
Sin, JH1
Lefrère, B1
Ulmann, G1
Chartier, M1
Patkaï, J1
Cynober, L1
Neveux, N1
Elbakary, NAH1
Ouanes, S1
Abengaña, J1
Chong, MS1
Tay, L1
Ahmed, U2
Jones, H2
James, BO1
LEHMANN, HE2
HANRAHAN, GE1
SETTEL, E1
TERMAN, LA1
RETTIG, JH1
GRIGOROVA, EV2
KISLENKOV, VA2
USHAKOV, GK2
VERBLIUNSKAIA, AA2
POLLASTRI, S1
SALATI, O1
TROUT, DL1
POUGETOUX, J1
DEUTSCH, H1
TSELIBEEV, BA1
ABRAMCZUK, J1
Dent, J1
Cunningham, SL1
Winkelman, JW1
Dorsey, CM1
Lukas, SE1
Richardson, GS1
Sholar, MB1
Hunt, A1
Hatch, CD1
Lund, BC1
Perry, PJ1
O'Brien, JF1
Falk, JL1
Carey, BE1
Malone, LC1
Klein, DF1
Dufresne, RL1
Wagner, RL1
Muskin, PR1
Mellman, LA1
Kornfeld, DS1

Reviews

1 review available for chlorpromazine and Psychomotor Agitation

ArticleYear
Chlorpromazine for psychosis induced aggression or agitation.
    The Cochrane database of systematic reviews, 2010, Apr-14, Issue:4

    Topics: Administration, Oral; Aggression; Antipsychotic Agents; Chlorpromazine; Haloperidol; Humans; Injecti

2010

Trials

2 trials available for chlorpromazine and Psychomotor Agitation

ArticleYear
Rapid tranquillisation in a psychiatric emergency hospital in Lebanon: TREC-Lebanon - a pragmatic randomised controlled trial of intramuscular haloperidol and promethazine
    Psychological medicine, 2022, Volume: 52, Issue:13

    Topics: Antipsychotic Agents; Chlorpromazine; Haloperidol; Hospitals, Psychiatric; Humans; Lebanon; Prometha

2022
Rectal thiopental compared with intramuscular meperidine, promethazine, and chlorpromazine for pediatric sedation.
    Annals of emergency medicine, 1991, Volume: 20, Issue:6

    Topics: Administration, Rectal; Blood Gas Analysis; Child; Child, Preschool; Chlorpromazine; Double-Blind Me

1991

Other Studies

23 other studies available for chlorpromazine and Psychomotor Agitation

ArticleYear
Safety and Effectiveness of Intravenous Chlorpromazine for Agitation in Critically Ill Patients.
    Journal of intensive care medicine, 2020, Volume: 35, Issue:10

    Topics: Administration, Intravenous; Adult; Aged; Antipsychotic Agents; Arrhythmias, Cardiac; Blood Pressure

2020
Malnutrition with hypoaminoacidemia in a 22-year-old pregnant patient masking a likely ornithine transcarbamylase deficiency.
    Clinical nutrition ESPEN, 2019, Volume: 30

    Topics: Anti-Bacterial Agents; Antiemetics; Chlorpromazine; DNA Mutational Analysis; Female; Humans; Infant,

2019
First generation antipsychotic-induced severe hypothermia: A case report and review of the literature.
    Asian journal of psychiatry, 2019, Volume: 44

    Topics: Antipsychotic Agents; Chlorpromazine; Diagnosis, Differential; Drug Administration Schedule; Female;

2019
Delirium superimposed on dementia: phenomenological differences between patients with and without behavioral and psychological symptoms of dementia in a specialized delirium unit.
    International psychogeriatrics, 2017, Volume: 29, Issue:3

    Topics: Aged; Aged, 80 and over; Chlorpromazine; Delirium; Dementia; Female; Humans; Length of Stay; Linear

2017
Rapid tranquillization agents for severe behavioural disturbance: a survey of African psychiatrists' prescription patterns.
    Tropical doctor, 2011, Volume: 41, Issue:1

    Topics: Africa; Chlorpromazine; Diazepam; Health Care Surveys; Humans; Mental Disorders; Practice Patterns,

2011
Chlorpromazine for psychosis-induced aggression or agitation.
    Schizophrenia bulletin, 2011, Volume: 37, Issue:5

    Topics: Administration, Oral; Aggression; Antipsychotic Agents; Chlorpromazine; Double-Blind Method; Humans;

2011
Chlorpromazine; new inhibiting agent for psychomotor excitement and manic states.
    A.M.A. archives of neurology and psychiatry, 1954, Volume: 71, Issue:2

    Topics: Autonomic Agents; Bipolar Disorder; Chlorpromazine; Humans; Mental Disorders; Psychomotor Agitation;

1954
[An inhibiting drug for control and treatment of psychomotoric states of excitability (chlorpromazine, largactil, thorazine, megaphen)].
    Der Nervenarzt, 1954, Aug-20, Volume: 25, Issue:8

    Topics: Chlorpromazine; Mental Disorders; Psychomotor Agitation

1954
Chlorpromazine in the treatment of senile agitation.
    GP, 1955, Volume: 12, Issue:6

    Topics: Aged; Chlorpromazine; Disease; Humans; Mental Disorders; Psychomotor Agitation

1955
Treatment of senile agitation with chlorpromazine.
    Geriatrics, 1955, Volume: 10, Issue:11

    Topics: Chlorpromazine; Dementia; Mental Disorders; Psychomotor Agitation; Psychotic Disorders

1955
Chlorpromazine for the control of psychomotor excitement in the mentally deficient; a preliminary study.
    The Journal of nervous and mental disease, 1955, Volume: 122, Issue:2

    Topics: Behavior; Chlorpromazine; Humans; Intellectual Disability; Psychomotor Agitation

1955
[Arrest of psychomotor excitation with aminazine].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1956, Volume: 56, Issue:7

    Topics: Chlorpromazine; Law Enforcement; Psychomotor Agitation

1956
[Arrest of psychomotor excitation with aminazine].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1956, Volume: 56, Issue:7

    Topics: Chlorpromazine; Law Enforcement; Psychomotor Agitation

1956
[Arrest of psychomotor excitation with aminazine].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1956, Volume: 56, Issue:7

    Topics: Chlorpromazine; Law Enforcement; Psychomotor Agitation

1956
[Arrest of psychomotor excitation with aminazine].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1956, Volume: 56, Issue:7

    Topics: Chlorpromazine; Law Enforcement; Psychomotor Agitation

1956
[Chlorpromazine (largactil) in psychomotor agitation states after surgical operations].
    Minerva chirurgica, 1957, Jan-15, Volume: 12, Issue:1

    Topics: Chlorpromazine; Psychomotor Agitation; Surgical Procedures, Operative

1957
A method of estimating drug effects on central excitability of the Siamese fighting fish.
    Archives internationales de pharmacodynamie et de therapie, 1957, Aug-01, Volume: 111, Issue:3

    Topics: Animals; Chlorpromazine; Fishes; Pentylenetetrazole; Perciformes; Psychomotor Agitation

1957
[Study of neuromuscular excitability during the course of prolonged neuroleptic treatment (chlorpromazine & reserpine); technic, results, pathogenic considerations].
    Journal de medecine de Lyon, 1957, Nov-05, Volume: 38, Issue:908

    Topics: Antipsychotic Agents; Chlorpromazine; Muscles; Psychomotor Agitation; Reserpine

1957
[Pathogenesis of excitability in insulin therapy and its control].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1957, Volume: 57, Issue:12

    Topics: Chlorpromazine; Convulsive Therapy; Humans; Insulin; Psychomotor Agitation

1957
[On the appearance of acathisia during neuroleptic therapy].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1960, Dec-26, Volume: 15

    Topics: Antipsychotic Agents; Chlorpromazine; Humans; Movement; Movement Disorders; Psychiatric Somatic Ther

1960
Catatonic syndrome following recovery from neuroleptic malignant syndrome.
    Journal of intellectual disability research : JIDR, 1995, Volume: 39 ( Pt 5)

    Topics: Anti-Anxiety Agents; Antipsychotic Agents; Catatonia; Chlorpromazine; Diazepam; Dose-Response Relati

1995
An electromyographic marker for neuroleptic-induced akathisia: preliminary measures of sensitivity and specificity.
    Clinical neuropharmacology, 1996, Volume: 19, Issue:4

    Topics: Adolescent; Adult; Age Factors; Aged; Antipsychotic Agents; Chlorpromazine; Electromyography; Female

1996
Failed challenge with quetiapine after neuroleptic malignant syndrome with conventional antipsychotics.
    Pharmacotherapy, 2001, Volume: 21, Issue:8

    Topics: Alzheimer Disease; Antipsychotic Agents; Chlorpromazine; Dibenzothiazepines; Haloperidol; Humans; Hy

2001
Schizophrenia and bipolar affective disorders: likenesses and differences.
    The Hillside journal of clinical psychiatry, 1989, Volume: 11, Issue:1

    Topics: Acute Disease; Bipolar Disorder; Chlorpromazine; Chronic Disease; Delusions; Depressive Disorder; Hu

1989
Antipsychotic-withdrawal akathisia versus antipsychotic-induced akathisia: further evidence for the existence of tardive akathisia.
    The Journal of clinical psychiatry, 1988, Volume: 49, Issue:11

    Topics: Adult; Akathisia, Drug-Induced; Ambulatory Care; Antipsychotic Agents; Basal Ganglia Diseases; Chlor

1988
A "new" drug for treating agitation and psychosis in the general hospital: chlorpromazine.
    General hospital psychiatry, 1986, Volume: 8, Issue:6

    Topics: Adolescent; Adult; Aged; Arousal; Chlorpromazine; Dose-Response Relationship, Drug; Hospitals, Gener

1986