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chlorpromazine and Priapism

chlorpromazine has been researched along with Priapism in 20 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Priapism: A prolonged painful erection that may lasts hours and is not associated with sexual activity. It is seen in patients with SICKLE CELL ANEMIA, advanced malignancy, spinal trauma; and certain drug treatments.

Research Excerpts

ExcerptRelevanceReference
"To investigate the mechanism of drug-induced priapism, we gave the antipsychotic agent chlorpromazine and the antidepressant trazodone to 14 dogs by intravenous and intracorporeal injection."7.67Priapism induced by chlorpromazine and trazodone: mechanism of action. ( Abber, JC; Juenemann, KP; Lue, TF; Luo, JA; Tanagho, EA, 1987)
"A patient developed priapism following a single intramuscular injection of chlorpromazine for hiccups."7.65Priapism as a sequela of chlorpromazine therapy. ( Merkin, TE, 1977)
"Stuttering Priapism is a recurrent, persistent penile erection in the absence of sexual desire due to altered genital hemodynamics, affecting the arterial component (high flow, non-ischemic) or the veno-occlusive mechanism (low flow, ischemic)."5.48Successful Management of Psychotropics Induced Stuttering Priapism with Pseudoephedrine in a Patient with Schizophrenia. ( Birur, B; Nagaraja, S; Pandurangi, A; Thippaiah, SM, 2018)
"Priapism is the prolonged, painful erection of penile tissue not accompanied by sexual arousal."5.43Risperidone, quetiapine and chlorpromazine may have induced priapism in an adolescent. ( Baytunca, MB; Erermis, S; Kose, S; Ozbaran, B, 2016)
"Priapism is an uncommon urologic emergency with a variety of known etiologies including the use of psychotropic medications."5.32Priapism in a patient receiving long-term chlorpromazine therapy. A case report. ( Bedir, S; Dayanç, M; Kilciler, M; Peker, AF; Sümer, F, 2003)
"Priapism is a pathologically prolonged and painful penile erection, usually unassociated with sexual desire or intercourse."5.30Priapism induced by chlorpromazine. ( Culha, M; Gökalp, A; Mutlu, N; Ozkurkcugil, C; Turkan, S, 1999)
"The pathophysiology and treatment of priapism are reviewed."5.28Self-administered intraurethral chlorpromazine: an unusual cause of priapism. ( Jackson, SC; Walker, JS, 1991)
"Stuttering Priapism is a recurrent, persistent penile erection in the absence of sexual desire due to altered genital hemodynamics, affecting the arterial component (high flow, non-ischemic) or the veno-occlusive mechanism (low flow, ischemic)."1.48Successful Management of Psychotropics Induced Stuttering Priapism with Pseudoephedrine in a Patient with Schizophrenia. ( Birur, B; Nagaraja, S; Pandurangi, A; Thippaiah, SM, 2018)
"Priapism is the prolonged, painful erection of penile tissue not accompanied by sexual arousal."1.43Risperidone, quetiapine and chlorpromazine may have induced priapism in an adolescent. ( Baytunca, MB; Erermis, S; Kose, S; Ozbaran, B, 2016)
"Priapism is a urologic emergency, and a urologic consultation should be obtained as early as possible."1.33Priapism associated with typical and atypical antipsychotic medications. ( Chen, CD; Kao, WT; Lung, FW; Tung, YP; Wang, CS, 2006)
"Priapism is a rare but serious adverse effect of psychotropic drugs resulting from their peripheral alpha-adrenoreceptor blocking action."1.27Priapism and psychotropic medication. ( de Alwis, C; Kogeorgos, J, 1986)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-199012 (60.00)18.7374
1990's3 (15.00)18.2507
2000's3 (15.00)29.6817
2010's2 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Thippaiah, SM1
Nagaraja, S1
Birur, B1
Pandurangi, A1
Baytunca, MB1
Kose, S1
Ozbaran, B1
Erermis, S1
Kilciler, M1
Bedir, S1
Sümer, F1
Dayanç, M1
Peker, AF1
Priyadarshi, S1
Wang, CS1
Kao, WT1
Chen, CD1
Tung, YP1
Lung, FW1
Griffith, SR1
Zil, JS1
Mutlu, N1
Ozkurkcugil, C1
Culha, M1
Turkan, S1
Gökalp, A1
Merkin, TE1
Gottlieb, JI1
Lustberg, T1
Moloney, PJ1
Elliott, GB1
Johnson, HW1
Jackson, SC1
Walker, JS1
Chen, EY1
Lee, AS1
Balon, R1
Berchou, R1
Han, H1
Abber, JC1
Lue, TF1
Luo, JA1
Juenemann, KP1
Tanagho, EA1
Kogeorgos, J1
de Alwis, C1
Bastecký, J1
Gregová, L1
Karayalcin, G1
Imran, M1
Rosner, F1
Bourgeois, M1
Dawson-Butterworth, K2

Trials

1 trial available for chlorpromazine and Priapism

ArticleYear
Oral terbutaline in the management of pharmacologically induced prolonged erection.
    International journal of impotence research, 2004, Volume: 16, Issue:5

    Topics: Adrenergic beta-Agonists; Adult; Aged; Antipsychotic Agents; Chlorpromazine; Humans; Injections; Mal

2004

Other Studies

19 other studies available for chlorpromazine and Priapism

ArticleYear
Successful Management of Psychotropics Induced Stuttering Priapism with Pseudoephedrine in a Patient with Schizophrenia.
    Psychopharmacology bulletin, 2018, 02-05, Volume: 48, Issue:2

    Topics: Adult; Antipsychotic Agents; Bronchodilator Agents; Chlorpromazine; Humans; Male; Priapism; Pseudoep

2018
Risperidone, quetiapine and chlorpromazine may have induced priapism in an adolescent.
    Pediatrics international : official journal of the Japan Pediatric Society, 2016, Volume: 58, Issue:1

    Topics: Adolescent; Antipsychotic Agents; Attention Deficit Disorder with Hyperactivity; Chlorpromazine; Dru

2016
Priapism in a patient receiving long-term chlorpromazine therapy. A case report.
    Urologia internationalis, 2003, Volume: 71, Issue:1

    Topics: Adult; Antipsychotic Agents; Chlorpromazine; Humans; Male; Priapism; Suction; Therapeutic Irrigation

2003
Priapism associated with typical and atypical antipsychotic medications.
    International clinical psychopharmacology, 2006, Volume: 21, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adult; Antipsychotic Agents; Chlorpromazine; Humans; Male; Priapism; R

2006
Priapism in a patient receiving antipsychotic therapy.
    Psychosomatics, 1984, Volume: 25, Issue:8

    Topics: Chlorpromazine; Erectile Dysfunction; Humans; Male; Middle Aged; Priapism

1984
Priapism induced by chlorpromazine.
    International journal of clinical practice, 1999, Volume: 53, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adult; Aged; Chlorpromazine; Humans; Male; Priapism

1999
Priapism as a sequela of chlorpromazine therapy.
    JACEP, 1977, Volume: 6, Issue:8

    Topics: Adult; Chlorpromazine; Heparin; Humans; Male; Priapism; Therapeutic Irrigation

1977
Phenothiazine-induced priapism: a case report.
    The American journal of psychiatry, 1977, Volume: 134, Issue:12

    Topics: Adult; Chlorpromazine; Depression; Humans; Male; Mesoridazine; Priapism; Schizophrenia

1977
Experiences with priapism.
    The Journal of urology, 1975, Volume: 114, Issue:1

    Topics: Anesthesia, Epidural; Child; Chlorpromazine; Drainage; Erectile Dysfunction; Humans; Male; Methods;

1975
Self-administered intraurethral chlorpromazine: an unusual cause of priapism.
    The American journal of emergency medicine, 1991, Volume: 9, Issue:2

    Topics: Adult; Chlorpromazine; Clinical Protocols; Emergency Service, Hospital; Humans; Instillation, Drug;

1991
Neuroleptic-induced priapism, hepatotoxicity and subsequent impotence in a patient with depressive psychosis.
    The British journal of psychiatry : the journal of mental science, 1990, Volume: 157

    Topics: Chemical and Drug Induced Liver Injury; Chlorpromazine; Depressive Disorder; Dose-Response Relations

1990
Priapism associated with thiothixene, chlorpromazine, and thioridazine.
    The Journal of clinical psychiatry, 1987, Volume: 48, Issue:5

    Topics: Adult; Bipolar Disorder; Chlorpromazine; Humans; Male; Priapism; Thioridazine; Thiothixene

1987
Priapism induced by chlorpromazine and trazodone: mechanism of action.
    The Journal of urology, 1987, Volume: 137, Issue:5

    Topics: Animals; Chlorpromazine; Dogs; Male; Penile Erection; Penis; Priapism; Regional Blood Flow; Trazodon

1987
Priapism and psychotropic medication.
    The British journal of psychiatry : the journal of mental science, 1986, Volume: 149

    Topics: Adult; Chlormethiazole; Chlorpromazine; Humans; Male; Munchausen Syndrome; Priapism; Promazine; Schi

1986
Priapism as a possible complication of the chlorpromazine treatment.
    Activitas nervosa superior, 1974, Volume: 16, Issue:3

    Topics: Adult; Bipolar Disorder; Chlorpromazine; Humans; Male; Priapism

1974
Priapism in sickle cell disease: report of five cases.
    The American journal of the medical sciences, 1972, Volume: 264, Issue:4

    Topics: Adult; Anemia, Sickle Cell; Blood Transfusion; Chlorpromazine; Codeine; Diethylstilbestrol; Drainage

1972
[Priapisms during neuroleptic drug administration (3 cases)].
    La Nouvelle presse medicale, 1972, Apr-22, Volume: 1, Issue:17

    Topics: Adult; Chlorpromazine; Haloperidol; Humans; Male; Mental Disorders; Methotrimeprazine; Priapism; Tra

1972
Priapism and phenothiazines.
    British medical journal, 1970, Oct-10, Volume: 4, Issue:5727

    Topics: Blood Pressure; Chlorpromazine; Humans; Male; Phenothiazines; Priapism; Schizophrenia

1970
Idiopathic priapism associated with schizophrenia.
    The British journal of clinical practice, 1969, Volume: 23, Issue:3

    Topics: Adult; Chlorpromazine; Humans; Male; Priapism; Schizophrenia

1969