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chlorpromazine and Poisoning

chlorpromazine has been researched along with Poisoning in 44 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Poisoning: Used with drugs, chemicals, and industrial materials for human or animal poisoning, acute or chronic, whether the poisoning is accidental, occupational, suicidal, by medication error, or by environmental exposure.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the impact of this change and of the withdrawal of thioridazine in 2000 on antipsychotic-related fatal poisoning, we reviewed all such deaths in England and Wales 1993-2013 recorded on the Office for National Statistics drug poisoning deaths database."8.93Antipsychotic-related fatal poisoning, England and Wales, 1993-2013: impact of the withdrawal of thioridazine. ( Flanagan, RJ; Handley, S; Patel, MX, 2016)
"For chlorpromazine, there was no dose-response relationship for ECG changes, but there was a significant dose-response relationship for increasing heart rate and reduction in mean blood pressure."5.32Electrocardiogram and cardiovascular changes in thioridazine and chlorpromazine poisoning. ( Bateman, DN; Kelly, CA; Strachan, EM, 2004)
"To evaluate the impact of this change and of the withdrawal of thioridazine in 2000 on antipsychotic-related fatal poisoning, we reviewed all such deaths in England and Wales 1993-2013 recorded on the Office for National Statistics drug poisoning deaths database."4.93Antipsychotic-related fatal poisoning, England and Wales, 1993-2013: impact of the withdrawal of thioridazine. ( Flanagan, RJ; Handley, S; Patel, MX, 2016)
" Paracetamol, amitriptyline, chlorpromazine, ferrous sulphate, kerosene, organophosphates, carbon monoxide, snake bite, alcohol and rodenticides were involved in the poisoning."3.91Childhood Drug and Non-Drug Poisoning in Nigeria: An Economic Appraisal. ( Chijioke-Nwauche, I; Ikhile, I; Orisakwe, OE, 2019)
"As outpatient treatment of schizophrenia increases, cases of over-dose with phenothiazine drugs may be expected to increase also."1.25Phenothiazine poisoning. A review of 48 cases. ( Barry, D; Becker, CE; Meyskens, FL, 1973)

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-199039 (88.64)18.7374
1990's1 (2.27)18.2507
2000's2 (4.55)29.6817
2010's2 (4.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ikhile, I1
Chijioke-Nwauche, I1
Orisakwe, OE1
Handley, S1
Patel, MX1
Flanagan, RJ1
VALLAT, JN1
LEONI, G1
HANNIGAN, CA1
AMBROSE, C1
GRAGE, H1
BETTINI, S1
CANTORE, G1
HENNE, M1
HENNE, S1
MCQUEEN, EG1
MEYLER, L1
SCHALM, L1
STEINICKE, O1
ZACHAU-CHRISTIANSEN, B1
VANDENBRANDE, J1
FROMMEL, E1
FLEURY, C1
LEDEBUR, IV1
BEGUIN, M1
FAMILY, S1
LAPOLLA, A1
NASH, LR1
PIVONT, G1
DRISKET, L1
NEVEN, M1
SINHA, GB1
MITRA, SK1
LANGERON, L1
CROCCEL, L1
DE SWARTE, D1
ANDERSON, D1
Strachan, EM1
Kelly, CA1
Bateman, DN1
Isbister, GK1
Balit, CR1
Kilham, HA1
Steel, CM1
O'Duffy, J1
Brown, SS1
Goulon, M1
Nouailhat, F1
Lévy-Alcover, MA1
Dordain, G1
Goulding, R1
Duffy, N1
Barbour, BH1
LaSette, AM1
Koffler, A1
Way, JL1
Burrows, G1
Barry, D1
Meyskens, FL1
Becker, CE1
Nazardinov, FV1
Spitsin, MN1
Winter, M1
Taylor, DJ1
Nasilowski, W1
Sybirska, H1
Gajdzińska, H1
Lemke, H1
Oettel, M1
Chemnitius, KH1
Baber, WS1
Lindsay, JS1
Pollard, DE1
Ianzito, BM2
Liskow, B1
Stewart, MA1
Consroe, PF1
Billets, S1
Carruth, J1
Einolf, N1
Ward, R1
Fenselau, C1
Gabel, M1
Trautmann, A1
Reid, DD1
Kerr, WC1
Chin, L1
Picchioni, AL1
Duplisse, BR1
Rudakov, AF1
Bonnichsen, R1
Geertinger, P1
Maehly, AC1
Almazova, IG1
Raudonat, HW1
Staak, M1

Reviews

2 reviews available for chlorpromazine and Poisoning

ArticleYear
Antipsychotic-related fatal poisoning, England and Wales, 1993-2013: impact of the withdrawal of thioridazine.
    Clinical toxicology (Philadelphia, Pa.), 2016, Volume: 54, Issue:6

    Topics: Antipsychotic Agents; Benzodiazepines; Chlorpromazine; Clozapine; Drug Recalls; England; Heroin; Hum

2016
Antipsychotic poisoning in young children: a systematic review.
    Drug safety, 2005, Volume: 28, Issue:11

    Topics: Antipsychotic Agents; Aripiprazole; Benzodiazepines; Child; Child, Preschool; Chlorpromazine; Clozap

2005

Other Studies

42 other studies available for chlorpromazine and Poisoning

ArticleYear
Childhood Drug and Non-Drug Poisoning in Nigeria: An Economic Appraisal.
    Annals of global health, 2019, 07-09, Volume: 85, Issue:1

    Topics: Acetaminophen; Adolescent; Age Distribution; Amitriptyline; Analgesics, Non-Narcotic; Antipsychotic

2019
[Poisoning with chloropromazine (largactil) in the course of a suicide attempt].
    Journal de medecine de Bordeaux et du Sud-Ouest, 1954, Volume: 131, Issue:6

    Topics: Autonomic Agents; Chlorpromazine; Humans; Poisoning; Suicide; Suicide, Attempted

1954
[Histochemical study of phosphatase of the central nervous system in experimental poisoning by neuroplegics (largactil) and ganglioplegics].
    Giornale di psichiatria e di neuropatologia, 1955, Volume: 83, Issue:2

    Topics: Autonomic Agents; Biochemical Phenomena; Central Nervous System; Chlorpromazine; Humans; Phosphoric

1955
Bromide intoxication.
    The Journal of the Maine Medical Association, 1956, Volume: 47, Issue:3

    Topics: Bromides; Chlorpromazine; Hypnotics and Sedatives; Poisoning

1956
[Clinical experiences with megaphen, with special reference to its effects as antiepileptic drug and as adjuvant in cases of poisoning].
    Psychiatrie, Neurologie, und medizinische Psychologie, 1955, Volume: 7, Issue:11

    Topics: Adjuvants, Immunologic; Adjuvants, Pharmaceutic; Anticonvulsants; Chlorpromazine; Epilepsy; Nausea;

1955
[Protective action of ACTH, cortisone, calcium gluconate, pyrilamine (neoantergan), promethazine (fargan), and chlorpromazine (largactil) against experimental poisoning with Latrodectus venom in guinea pigs].
    Rendiconti - Istituto superiore di sanita, 1955, Volume: 18, Issue:6

    Topics: Adrenocorticotropic Hormone; Antipsychotic Agents; Calcium Gluconate; Chlorpromazine; Cortisone; Glu

1955
[Acute poisoning during attempted suicide by chlorpromazine].
    Annales medico-psychologiques, 1956, Volume: 114, Issue:2

    Topics: Chlorpromazine; Humans; Poisoning; Psychotropic Drugs; Suicide; Suicide, Attempted

1956
TOXIC EFFECTS OF PHENOTHIAZINE TRANQUILLIZERS.
    The New Zealand medical journal, 1963, Volume: 62

    Topics: Central Nervous System Diseases; Chlorpromazine; Epilepsy; Female; Fluphenazine; Hypotension; Jaundi

1963
[CHANGES IN THE BLOOD CAUSED BY DRUGS].
    Nederlands tijdschrift voor geneeskunde, 1963, Nov-09, Volume: 107

    Topics: Agranulocytosis; Anemia; Anemia, Aplastic; Anemia, Hemolytic; Chloramphenicol; Chlorpromazine; Drug

1963
[LIVER DAMAGE BY DRUGS].
    Nederlands tijdschrift voor geneeskunde, 1963, Dec-07, Volume: 107

    Topics: Aminosalicylic Acid; Aminosalicylic Acids; Arsphenamine; Chemical and Drug Induced Liver Injury; Chl

1963
[PHENOTHIAZINE AND CHLORPROTHIXENE POISONING IN CHILDREN].
    Nordisk medicin, 1964, Aug-27, Volume: 72

    Topics: Barbiturates; Child; Chlorpromazine; Chlorprothixene; Humans; Infant; Phenothiazines; Poisoning; Psy

1964
[ACUTE ACCIDENTAL DRUG POISONING IN CHILDREN].
    Belgisch tijdschrift voor geneeskunde, 1964, Aug-01, Volume: 20

    Topics: Accidents; Child; Chlorpromazine; Diagnosis; Drug Therapy; Hypnotics and Sedatives; Infant; Pharmace

1964
THE PLACE OF ACETYLSALICYLIC ACID IN PSYCHOPHARMACOLOGY. AN EXPERIMENTAL STUDY.
    Arzneimittel-Forschung, 1963, Volume: 13

    Topics: Amphetamine; Amphetamines; Animals; Aspirin; Body Temperature Regulation; Chlordiazepoxide; Chlorpro

1963
TWO SUICIDE ATTEMPTS WITH CHLORPROMAZINE.
    The American journal of psychiatry, 1965, Volume: 121

    Topics: Amphetamine; Chlorpromazine; Coma; Depression; Dextroamphetamine; Drug Therapy; Gastric Lavage; Hypo

1965
[Largactil (chlorpromazine) poisoning].
    Revue medicale de Liege, 1955, Feb-01, Volume: 10, Issue:3

    Topics: Chlorpromazine; Humans; Poisoning

1955
A case of acute chlorpromazine hydrochloride poisoning.
    Journal of the Indian Medical Association, 1955, Apr-16, Volume: 24, Issue:14

    Topics: Bipolar Disorder; Chlorpromazine; Humans; Mental Disorders; Poisoning; Psychotic Disorders

1955
[Voluntary poisoning by chlorpromazine].
    Journal des sciences medicales de Lille, 1955, Volume: 73, Issue:2

    Topics: Chlorpromazine; Humans; Poisoning; Suicide

1955
Opium poisoning precipitated by chlorpromazine.
    The Medical journal of Australia, 1955, Jun-11, Volume: 42, Issue:1 24

    Topics: Alcoholism; Chlorpromazine; Humans; Liver Cirrhosis; Opium; Poisoning

1955
Electrocardiogram and cardiovascular changes in thioridazine and chlorpromazine poisoning.
    European journal of clinical pharmacology, 2004, Volume: 60, Issue:8

    Topics: Adult; Antipsychotic Agents; Blood Pressure; Chlorpromazine; Dose-Response Relationship, Drug; Elect

2004
Clinical effects and treatment of imipramine and amitriptyline poisoning in children.
    British medical journal, 1967, Sep-09, Volume: 3, Issue:5566

    Topics: Accident Prevention; Amitriptyline; Blood Gas Analysis; Child; Chlorpromazine; Electrocardiography;

1967
[Toxic coma with autonomic sideration, with a favorable outcome].
    Revue neurologique, 1967, Volume: 116, Issue:4

    Topics: Adult; Amobarbital; Body Temperature; Brain; Cardiovascular System; Chlorpromazine; Coma; Diazepam;

1967
The treatment of acute poisoning.
    Transactions of the Medical Society of London, 1967, Volume: 83

    Topics: Acute Disease; Antidotes; Atropine; Barbiturates; Carbon Monoxide Poisoning; Chlorpromazine; Deferox

1967
A 33-year-old woman with a propranolol and chlorpromazine overdose, with applied nursing diagnoses.
    Journal of emergency nursing, 1993, Volume: 19, Issue:1

    Topics: Adult; Chlorpromazine; Critical Care; Drug Overdose; Education, Nursing, Continuing; Female; Glucago

1993
Fixed-bed charcoal hemoperfusion for the treatment of drug overdose.
    Kidney international. Supplement, 1976, Issue:7

    Topics: Adolescent; Adsorption; Adult; Blood Platelets; Charcoal; Chlordiazepoxide; Chlorpromazine; Ethchlor

1976
Cyanide intoxication: protection with chlorpromazine.
    Toxicology and applied pharmacology, 1976, Volume: 36, Issue:1

    Topics: Animals; Chlorpromazine; Cyanides; Drug Synergism; Lethal Dose 50; Mice; Nitrites; Poisoning; Thiosu

1976
Phenothiazine poisoning. A review of 48 cases.
    California medicine, 1973, Volume: 118, Issue:1

    Topics: Adult; Antipsychotic Agents; Child; Child, Preschool; Chlorpromazine; Female; Humans; Male; Poisonin

1973
[Experience with the use of chlorpromazine in the treatment of acute poisoning with organophosphorus compounds].
    Sovetskaia meditsina, 1974, Volume: 0, Issue:7

    Topics: Acute Disease; Chlorpromazine; Female; Humans; Male; Organophosphate Poisoning; Poisoning

1974
Letter: Danger of saline emetics in first-aid for poisoning.
    British medical journal, 1974, Sep-28, Volume: 3, Issue:5934

    Topics: Adult; Amitriptyline; Chlorides; Chlorpromazine; Diazepam; Emetics; Female; First Aid; Humans; Imipr

1974
Legal-medical and toxicological evaluation of 18 lethal cases of poisoning by phenothiazine derivatives.
    Zeitschrift fur Rechtsmedizin. Journal of legal medicine, 1974, Volume: 74, Issue:4

    Topics: Adult; Autopsy; Chlorpromazine; Chromatography, Paper; Chromatography, Thin Layer; Female; Humans; K

1974
[Pharmacologic-endocrinological findings in animal experiments with TURISYNCHRON and SUISYNCHROM. 2. Toxicologic findings].
    Archiv fur experimentelle Veterinarmedizin, 1974, Volume: 28, Issue:5

    Topics: Acute Disease; Administration, Oral; Animals; Atropine; Body Weight; Chlorpromazine; Chronic Disease

1974
General hospital psychiatry.
    The New Zealand medical journal, 1972, Volume: 76, Issue:486

    Topics: Adolescent; Adult; Age Factors; Aged; Amitriptyline; Amobarbital; Child; Child, Preschool; Chlorprom

1972
Reaction to LSD in a two-year-old child.
    The Journal of pediatrics, 1972, Volume: 80, Issue:4

    Topics: Child, Preschool; Chlorpromazine; Fear; Gastric Lavage; Hallucinations; Humans; Hyperkinesis; Lyserg

1972
Treatment of acute hallucinogenic drug toxicity: specific pharmacological intervention.
    American journal of hospital pharmacy, 1973, Volume: 30, Issue:1

    Topics: Amphetamine; Atropa belladonna; Chlorpromazine; Dronabinol; Hallucinogens; Humans; Lysergic Acid Die

1973
Rapid identification of acute drug intoxications.
    The Johns Hopkins medical journal, 1973, Volume: 133, Issue:3

    Topics: Acute Disease; Caffeine; Chlorpromazine; Gastric Lavage; Glutethimide; Humans; Mass Spectrometry; Me

1973
Treatment for ingestion of LSD.
    The Journal of pediatrics, 1972, Volume: 81, Issue:3

    Topics: Child, Preschool; Chlorpromazine; Diazepam; Drug Interactions; Humans; Lysergic Acid Diethylamide; P

1972
[Dialysis of drugs and poisons. 2].
    Medizinische Klinik, 1972, Nov-03, Volume: 67, Issue:44

    Topics: Acetaminophen; Aminopyrine; Amitriptyline; Aspirin; Carbamazepine; Chlordiazepoxide; Chlorpromazine;

1972
Phenelzine poisoning responding to phenothiazine.
    The Medical journal of Australia, 1969, Dec-13, Volume: 2, Issue:24

    Topics: Adult; Blood Pressure; Chlorpromazine; Drug Antagonism; Humans; Male; Meperidine; Phenelzine; Poison

1969
The action of activated charcoal on poisons in the digestive tract.
    Toxicology and applied pharmacology, 1970, Volume: 16, Issue:3

    Topics: Animals; Aspirin; Barbiturates; Charcoal; Chloroquine; Chlorpheniramine; Chlorpromazine; Digestive S

1970
[Resuscitation of children in acute drug poisoning using the method of forced diuresis].
    Pediatriia, 1970, Volume: 49, Issue:1

    Topics: Child; Child, Preschool; Chlorpromazine; Diuresis; Humans; Isoniazid; Methods; Phenothiazines; Poiso

1970
Toxicological data on phenothiazine drugs in autopsy cases.
    Zeitschrift fur Rechtsmedizin. Journal of legal medicine, 1970, Volume: 67, Issue:3

    Topics: Adolescent; Adult; Aged; Autopsy; Child; Child, Preschool; Chlorpromazine; Chromatography, Thin Laye

1970
[Changes in the nervous system during acute chlorpromazine poisoning in children].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1970, Volume: 70, Issue:10

    Topics: Adolescent; Child; Child, Preschool; Chlorpromazine; Humans; Infant; Nervous System; Neurologic Mani

1970
[Biochemical and medico-legal considerations of fatal megaphen (Chlorpromazine) poisoning in an infant. Problems in the separation of etiological relationships].
    Zeitschrift fur Rechtsmedizin. Journal of legal medicine, 1970, Volume: 67, Issue:2

    Topics: Child, Preschool; Chlorpromazine; Drug Synergism; Forensic Medicine; Humans; Phenobarbital; Poisonin

1970