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chlorpromazine and Pheochromocytoma

chlorpromazine has been researched along with Pheochromocytoma in 10 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Pheochromocytoma: A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)

Research Excerpts

ExcerptRelevanceReference
"Chlorpromazine (CPZ) is an effective cyanide antidote, with its greatest efficacy displayed when combined with the antidotes, sodium nitrite and sodium thiosulfate."1.27Cyanide-induced neurotoxicity: mechanisms of attenuation by chlorpromazine. ( Ardelt, BK; Borowitz, JL; Isom, GE; Johnson, JD; Maduh, EU, 1988)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-199010 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
LIMA, FP1
BARROS FILHO, NM1
FRANCA, HH1
LUND-JOHANSEN, P1
OMINE, H1
KONTA, R1
KANDA, Y1
YONEYA, T1
ENDO, Y1
FUJIKI, K1
KOYANAGI, S1
TAKAYA, H1
POOLE, A1
KNOX, J1
SLESSOR, A1
Tominaga, S1
Cremins, J1
Wagner, JA1
Halegoua, S1
Matsuda, Y1
Guroff, G1
Maduh, EU1
Johnson, JD1
Ardelt, BK1
Borowitz, JL1
Isom, GE1
Bingham, W1
Elliott, J1
Lyons, SM1

Other Studies

10 other studies available for chlorpromazine and Pheochromocytoma

ArticleYear
[Pheochromocytoma; considerations on diagnostic tests, with case report].
    Revista paulista de medicina, 1957, Volume: 50, Issue:2

    Topics: Chlorpromazine; Diagnostic Tests, Routine; Humans; Pheochromocytoma

1957
Shock after administration of phenothiazines in patients with pheochromocytoma.
    Acta medica Scandinavica, 1962, Volume: 172

    Topics: Antipsychotic Agents; Chlorpromazine; Chlorprothixene; Phenothiazines; Pheochromocytoma; Shock; Shoc

1962
[3 CASES OF PHEOCHROMOCYTOMA].
    Naika. Internal medicine, 1964, Volume: 13

    Topics: Adrenalectomy; Chlorpromazine; Diagnosis; Pathology; Phentolamine; Pheochromocytoma

1964
PHAEOCHROMOCYTOMA.
    The Medical journal of Australia, 1964, Sep-05, Volume: 2

    Topics: Catecholamines; Chlorpromazine; Diagnosis, Differential; Hyaluronoglucosaminidase; Hypertension; Hyp

1964
Phaeochromocytoma and neurofibromatosis; adrenolytic effect of phentolamine and chlorpromazine.
    Lancet (London, England), 1955, Apr-16, Volume: 268, Issue:6868

    Topics: Adrenergic Antagonists; Chlorpromazine; Humans; Neurofibromatoses; Neurofibromatosis 1; Paragangliom

1955
Histochemical studies on catecholamines (with special reference to the paraganglion).
    Nihon geka hokan. Archiv fur japanische Chirurgie, 1967, Jul-01, Volume: 36, Issue:4

    Topics: Adult; Animals; Catecholamines; Chlorpromazine; Chromaffin System; Female; Ganglia, Spinal; Histocyt

1967
Nerve growth factor action is mediated by cyclic AMP- and Ca+2/phospholipid-dependent protein kinases.
    The Journal of cell biology, 1986, Volume: 103, Issue:3

    Topics: Animals; Cell Line; Chlorpromazine; Cyclic AMP; Enzyme Activation; Nerve Growth Factors; Pheochromoc

1986
Purification and mechanism of activation of a nerve growth factor-sensitive S6 kinase from PC12 cells.
    The Journal of biological chemistry, 1987, Feb-25, Volume: 262, Issue:6

    Topics: Adrenal Gland Neoplasms; Animals; Calcium; Calmodulin; Cell Line; Chlorpromazine; Egtazic Acid; Kine

1987
Cyanide-induced neurotoxicity: mechanisms of attenuation by chlorpromazine.
    Toxicology and applied pharmacology, 1988, Volume: 96, Issue:1

    Topics: Adrenal Gland Neoplasms; Animals; Calcium; Chlorpromazine; Cyanides; Lipid Peroxides; Mice; Nervous

1988
Management of anaesthesia for phaeochromocytoma.
    Anaesthesia, 1972, Volume: 27, Issue:1

    Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Anesthesia, General; Arrhythmias, Cardiac; Blood Pressur

1972