chlorpromazine has been researched along with Peptic Ulcer in 26 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Peptic Ulcer: Ulcer that occurs in the regions of the GASTROINTESTINAL TRACT which come into contact with GASTRIC JUICE containing PEPSIN and GASTRIC ACID. It occurs when there are defects in the MUCOSA barrier. The common forms of peptic ulcers are associated with HELICOBACTER PYLORI and the consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).
| Excerpt | Relevance | Reference |
|---|---|---|
| " Eventual discontinuation of cimetidine therapy led to a return of schizophrenic symptoms, which responded to an increase in chlorpromazine dosage to previous levels." | 5.28 | Adverse interaction between cimetidine and chlorpromazine in two cases of chronic schizophrenia. ( Byrne, A; O'Shea, B, 1989) |
| "Chlorpromazine did not inhibit lesions formed after combining indomethacin with insulin in a dose of 3 IU/kg." | 1.28 | Effect of chlorpromazine on ulcer formation by indomethacin in histamine- and insulin-stimulated rats. ( Kohút, A; Mirossay, L; Nicák, A, 1991) |
| " Eventual discontinuation of cimetidine therapy led to a return of schizophrenic symptoms, which responded to an increase in chlorpromazine dosage to previous levels." | 1.28 | Adverse interaction between cimetidine and chlorpromazine in two cases of chronic schizophrenia. ( Byrne, A; O'Shea, B, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 25 (96.15) | 18.7374 |
| 1990's | 1 (3.85) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| GABLE, JJ | 1 |
| KEYRILAINEN, TO | 1 |
| KALLIOMAKI, JL | 1 |
| GRONROOS, M | 1 |
| SUN, DC | 1 |
| SHAY, H | 1 |
| SCARPONI, E | 1 |
| NORBIATO, L | 1 |
| SOCHA, P | 1 |
| KUHN, E | 2 |
| WEISS, Z | 1 |
| BUCHEL, L | 3 |
| GALLAIRE, D | 2 |
| TUBARO, E | 1 |
| KONTUREK, S | 1 |
| RADECKI, T | 1 |
| SELMECI, L | 1 |
| TOTH, T | 1 |
| METYSOVA, J | 1 |
| METYS, J | 1 |
| VOTAVA, Z | 1 |
| Harada, M | 1 |
| Mayuzumi, K | 1 |
| Yano, S | 1 |
| Mirossay, L | 1 |
| Kohút, A | 1 |
| Nicák, A | 1 |
| Byrne, A | 1 |
| O'Shea, B | 1 |
| Lévy, J | 1 |
| Moczurad, K | 1 |
| Lemke, H | 1 |
| Oettel, M | 1 |
| Chemnitius, KH | 1 |
| Nagura, M | 1 |
| Caprino, L | 1 |
| Borrelli, F | 1 |
| Falchetti, R | 1 |
| Chrostowski, K | 1 |
| Jeske, J | 1 |
| Summers, RW | 1 |
| Kent, TH | 1 |
| Osborne, JW | 1 |
| Brodie, DA | 1 |
| Cook, PG | 1 |
| Bauer, BJ | 1 |
| Dagle, GE | 1 |
| Dvorák, V | 1 |
| Zamrazil, V | 1 |
| Liblau, L | 1 |
| Murawsky, M | 1 |
| Prioux-Guyonneau, M | 1 |
2 reviews available for chlorpromazine and Peptic Ulcer
| Article | Year |
|---|---|
PROTEIN METABOLISM DURING THERAPEUTIC SLEEP.
Topics: Barbiturates; Chlorpromazine; Conditioning, Classical; Humans; Narcotherapy; Neurotic Disorders; Nit | 1963 |
[DRUGS ON DISPLAY].
Topics: Antihypertensive Agents; Antineoplastic Agents; Chlorpromazine; Chlorprothixene; Coumarins; Peptic U | 1963 |
24 other studies available for chlorpromazine and Peptic Ulcer
| Article | Year |
|---|---|
Jaundice associated with chlorpromazine therapy and peptic ulcer: report of two cases.
Topics: Chlorpromazine; Jaundice; Peptic Ulcer | 1955 |
Effects of reserpine and chlorpromazine on the Shay rat.
Topics: Animals; Chlorpromazine; Gastric Juice; Peptic Ulcer; Rats; Reserpine | 1957 |
Synergistic action of chlorpromazine and tricyclamol on basal gastric secretion in duodenal ulcer patients.
Topics: Chlorpromazine; Digestion; Duodenal Ulcer; Gastric Juice; Peptic Ulcer; Procyclidine; Trihexyphenidy | 1959 |
[Peptic ulcer].
Topics: Chlorpromazine; Humans; Peptic Ulcer | 1959 |
[The use of phenothiazine derivatives in stationary intestinal ulcer cure].
Topics: Antipsychotic Agents; Chlorpromazine; Intestinal Diseases; Peptic Ulcer; Phenothiazines; Ulcer | 1959 |
[STOMACH SURGERY UNDER LOCAL ANESTHESIA WITH NEUROPLEGIC PREMEDICATION].
Topics: Adjuvants, Anesthesia; Anesthesia, Local; Chlorpromazine; Ephedrine; Humans; Meperidine; Peptic Ulce | 1963 |
[REDUCTION OF DURATION OF CONSTRAINT FOR THE PRODUCTION OF EXPERIMENTAL ULCERS IN RATS. APPLICATION TO THE STUDY OF PROTECTIVE SUBSTANCES].
Topics: Atropine; Chlorpromazine; Muscle Relaxants, Central; Peptic Ulcer; Pharmacology; Rats; Research; Str | 1963 |
[CONTRIBUTION OF THE STUDY OF THE EFFECT OF THERAPEUTIC SLEEP ON METABOLISM. 4. EFFECT OF THERAPEUTIC SLEEP ON PROTEIN METABOLISM: C) CHANGES IN NITROGEN UTILIZATION].
Topics: Barbiturates; Biomedical Research; Chlorpromazine; Conditioning, Classical; Diet; Diet Therapy; Diet | 1964 |
[EFFECT OF LARGACTIL AND PHENERGAN ON GASTRIC SECRETION AND DEVELOPMENT OF EXPERIMENTAL PEPTIC ULCER].
Topics: Biomedical Research; Chlorpromazine; Gastric Acidity Determination; Gastric Juice; Peptic Ulcer; Pha | 1964 |
INFLUENCE OF COMBINED ATROPINE-CHLORBROMAZINE TREATMENT ON RESERPINE-INDUCED GASTRIC ULCER.
Topics: Anti-Allergic Agents; Atropine; Chlorpromazine; Gastric Juice; Histamine H1 Antagonists; Peptic Ulce | 1964 |
ATTEMPT TO DIFFERENTIATE THYMOLEPTICS AND NEUROLEPTICS BY MEANS OF THEIR INFLUENCE ON THE EFFECTS OF RESERPINE.
Topics: Amitriptyline; Antidepressive Agents; Antipsychotic Agents; Behavior, Animal; Body Temperature; Chlo | 1964 |
Peripheral and central effects of atropine and chlorpromazine on gastric motility and ulceration in stressed rats.
Topics: Animals; Atropine; Chlorpromazine; Gastrointestinal Motility; Injections, Intravenous; Injections, I | 1981 |
Effect of chlorpromazine on ulcer formation by indomethacin in histamine- and insulin-stimulated rats.
Topics: Animals; Anti-Ulcer Agents; Chlorpromazine; Gastric Acid; Gastric Mucosa; Histamine; Indomethacin; I | 1991 |
Adverse interaction between cimetidine and chlorpromazine in two cases of chronic schizophrenia.
Topics: Chlorpromazine; Cimetidine; Drug Interactions; Esophagitis, Peptic; Female; Humans; Male; Middle Age | 1989 |
[Action of substances protective against ulcers due to constraint in rats maintained at ambiant temperature of 14 degrees C].
Topics: Amphetamine; Animals; Atropine; Barbiturates; Bis-Trimethylammonium Compounds; Chlorpromazine; Dextr | 1967 |
[Clinical and experimental studies on the effect of neuroplegic drugs on gastric secretion and peptic ulcers].
Topics: Adolescent; Adult; Animals; Cats; Chlorpromazine; Depression, Chemical; Duodenal Ulcer; Female; Gast | 1974 |
[Pharmacologic-endocrinological findings in animal experiments with TURISYNCHRON and SUISYNCHROM. 2. Toxicologic findings].
Topics: Acute Disease; Administration, Oral; Animals; Atropine; Body Weight; Chlorpromazine; Chronic Disease | 1974 |
Effect of psychotropic drugs on catecholamines in brain and adrenal medulla of rats under stress producing peptic ulcers.
Topics: Adrenal Medulla; Animals; Brain Chemistry; Catecholamines; Chlorpromazine; Denervation; Dopamine; Im | 1972 |
General pharmacological properties of 4,5-diphenyl-2-bis-(2-hydroxyethyl)-aminoxazol (ditazol).
Topics: Amphetamine; Animals; Anti-Inflammatory Agents; Atropine; Blood Pressure; Cats; Chlorpromazine; Etha | 1973 |
[Properties of drugs decreasing gastric acidity in endoradiosound-controlled treatment of peptic ulcer].
Topics: Acid-Base Equilibrium; Adolescent; Adult; Chlorpromazine; Female; Gastric Acidity Determination; Hum | 1972 |
Effects of drugs, ileal obstruction, and irradiation on rat gastrointestinal propulsion.
Topics: Animals; Chlorisondamine; Chlorpromazine; Chromium Isotopes; Fasting; Gastrointestinal Motility; Ile | 1970 |
Indomethacin-induced intestinal lesions in the rat.
Topics: Administration, Oral; Animals; Antacids; Aspirin; Atropine; Bile Ducts; Bretylium Compounds; Chlorpr | 1970 |
[Effect of chlorpromazine on the glucose tolerance test after triamcinolone administration].
Topics: Adolescent; Adult; Blood Glucose; Chlorpromazine; Female; Glucose Tolerance Test; Humans; Male; Meth | 1971 |
[Influence of pyschotropic substances on variations of total plasma free fatty acids in constrained rats].
Topics: Animals; Chlorpromazine; Depression, Chemical; Dextromoramide; Fatty Acids, Nonesterified; Female; H | 1969 |