chlorpromazine has been researched along with Parkinsonian Disorders in 33 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Parkinsonian Disorders: A group of disorders which feature impaired motor control characterized by bradykinesia, MUSCLE RIGIDITY; TREMOR; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see PARKINSON DISEASE), secondary parkinsonism (see PARKINSON DISEASE, SECONDARY) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the BASAL GANGLIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Parkinsonism is characterized by rest tremor, inflexibility, balance debilitation, slow motion and dementia." | 1.48 | Anticataleptic activity of Zamzam water in chlorpromazine induced animal model of Parkinson disease. ( Ikram, R; Riaz, B; Sikandar, B, 2018) |
| "Catalepsy was assessed by Bar test on day 21 and day 30 at 30, 60, 90 and 120 minutes interval." | 1.43 | Beneficial anti-Parkinson effects of camel milk in Chlorpromazineinduced animal model: Behavioural and histopathological study. ( Khatoon, H; Mirza, T; Najam, R; Sikandar, B, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (78.79) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (6.06) | 29.6817 |
| 2010's | 4 (12.12) | 24.3611 |
| 2020's | 1 (3.03) | 2.80 |
| Authors | Studies |
|---|---|
| Khan, SS | 2 |
| Ikram, R | 3 |
| Naeem, S | 2 |
| Khatoon, H | 2 |
| Anser, H | 1 |
| Sikander, B | 1 |
| Rao, SS | 1 |
| Riaz, B | 1 |
| Sikandar, B | 2 |
| Najam, R | 1 |
| Mirza, T | 1 |
| Kane, JM | 1 |
| Correll, CU | 1 |
| Harris, DS | 1 |
| Wolkowitz, OM | 1 |
| Reus, VI | 1 |
| Teixeira, AL | 1 |
| Cardoso, F | 1 |
| Maia, DP | 1 |
| Cunningham, MC | 1 |
| BERGOUIGNAN, M | 1 |
| BENTE, D | 1 |
| ITIL, T | 1 |
| MEGGIO, B | 1 |
| CATTANI, F | 1 |
| FREYHAN, FA | 1 |
| NAHUNEK, K | 1 |
| RYBAKOVA, V | 1 |
| KNAUF, HW | 1 |
| CAHAN, RB | 1 |
| PARRISH, DD | 1 |
| GUGGENHEIM, P | 1 |
| COHEN, L | 1 |
| MERIAUX, J | 1 |
| NAVARRANNE, P | 1 |
| STRATAS, NE | 1 |
| PHILLIPS, RD | 1 |
| WALKER, PA | 1 |
| SANDIFER, MG | 1 |
| RAVKIN, IG | 1 |
| NEHLIL, J | 1 |
| BOHACEK, N | 1 |
| HAJNSEK, F | 1 |
| SARTORIUS, N | 1 |
| MACKIEWICZ, J | 1 |
| GERSHON, S | 1 |
| LICHTIGFELD, FJ | 1 |
| NAYRAC, P | 1 |
| ARNOTT, G | 1 |
| MILBLED, G | 1 |
| BARUK, H | 1 |
| LAUNAY, J | 1 |
| GEORGIADES, G | 1 |
| KYRATSOS, C | 1 |
| MICHAILIDES, G | 1 |
| TSINOPOULOS, T | 1 |
| ZSCHUCKE, CF | 1 |
| BOCKNER, S | 1 |
| STERN, J | 1 |
| WARD, AA | 1 |
| HUNTER, R | 1 |
| EARL, CJ | 1 |
| THRONICROFT, S | 1 |
| DESCHAEPDRYVER, A | 1 |
| LAVERTY, R | 1 |
| SHARMAN, DF | 1 |
| HAASE, HJ | 1 |
| POURSINES, Y | 1 |
| ALLIEZ, J | 1 |
| TOGA, M | 1 |
2 reviews available for chlorpromazine and Parkinsonian Disorders
| Article | Year |
|---|---|
Past and present progress in the pharmacologic treatment of schizophrenia.
Topics: Antipsychotic Agents; Chlorpromazine; Clozapine; Controlled Clinical Trials as Topic; Diabetes Melli | 2010 |
[PSYCHOPHARMACA: OBSERVATIONS AND INTERPRETATIONS].
Topics: Amphetamine; Amphetamines; Caudate Nucleus; Central Nervous System Stimulants; Chlorpromazine; Dihyd | 1964 |
31 other studies available for chlorpromazine and Parkinsonian Disorders
| Article | Year |
|---|---|
Effect of M. chamomilla L. tea on chlorpromazine induced catalepsy: A neuroprotective study.
Topics: Animals; Antiparkinson Agents; Behavior, Animal; Brain; Catalepsy; Chlorpromazine; Disease Models, A | 2020 |
NSAIDs ameliorate cognitive and motor impairment in a model of parkinsonism induced by chlorpromazine.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipsychotic Agents; Behavior, Animal; Chlorproma | 2017 |
Anticataleptic activity of Zamzam water in chlorpromazine induced animal model of Parkinson disease.
Topics: Animals; Brain; Carbidopa; Catalepsy; Chlorpromazine; Disease Models, Animal; Drug Combinations; Hyd | 2018 |
Beneficial anti-Parkinson effects of camel milk in Chlorpromazineinduced animal model: Behavioural and histopathological study.
Topics: Animals; Antiparkinson Agents; Behavior, Animal; Brain; Camelus; Carbidopa; Catalepsy; Chlorpromazin | 2016 |
Movement disorder, memory, psychiatric symptoms and serum DHEA levels in schizophrenic and schizoaffective patients.
Topics: Adult; Aged; Antipsychotic Agents; Chlorpromazine; Dehydroepiandrosterone; Female; Humans; Hydrocort | 2001 |
Sydenham's chorea may be a risk factor for drug induced parkinsonism.
Topics: Antipsychotic Agents; Chlorpromazine; Chorea; Humans; Parkinsonian Disorders; Retrospective Studies; | 2003 |
[Reversible parkinsonism in the course of largactil therapy of vomiting in pregnancy].
Topics: Chlorpromazine; Female; Parkinson Disease; Parkinsonian Disorders; Pregnancy; Pregnancy Complication | 1954 |
[The effects of high-dosed reserpin (serpasil) treatment and drug-induced parkinsonism-like states on the electroencephalogram].
Topics: Antihypertensive Agents; Chlorpromazine; Electroencephalography; Humans; Parkinson Disease; Parkinso | 1955 |
[Hypothesis on the mechanism of action of chlorpromazine (largactil) on the extrapyramidal manifestations of the parkinsonian syndrome].
Topics: Chlorpromazine; Parkinson Disease; Parkinsonian Disorders | 1955 |
Psychomotility and parkinsonism in treatment with neuroleptic drugs.
Topics: Antipsychotic Agents; Chlorpromazine; Electroconvulsive Therapy; Humans; Mental Disorders; Movement; | 1957 |
[Parkinsonism-like symptoms caused by chlorpromazine therapy].
Topics: Chlorpromazine; Electroconvulsive Therapy; Humans; Parkinson Disease; Parkinsonian Disorders; Psycho | 1958 |
[Treatment of parkinsonism-like syndromes caused by reserpine & chlorpromazine].
Topics: Chlorpromazine; Humans; Parkinson Disease; Parkinsonian Disorders; Piperidines; Reserpine; Syndrome | 1958 |
Reversibility of drug-induced parkinsonism.
Topics: Chlorpromazine; Parkinson Disease; Parkinsonian Disorders; Reserpine | 1960 |
Theoretical considerations in parkinsonism induced by tranquilizing drugs.
Topics: Chlorpromazine; Parkinson Disease; Parkinsonian Disorders; Reserpine; Tranquilizing Agents | 1959 |
[Paradoxical parkinsonian syndrome after drug ingestion in a patient with portacaval anastomosis].
Topics: Chlorpromazine; Parkinson Disease; Parkinsonian Disorders; Portacaval Shunt, Surgical | 1963 |
A study of drug-induced parkinsonism.
Topics: Chlorpromazine; Humans; Mental Disorders; Parkinson Disease; Parkinsonian Disorders; Prochlorperazin | 1963 |
[THE PROBLEM OF ALLERGY IN PSYCHIATRY].
Topics: Chlorpromazine; Drug Hypersensitivity; Epilepsy; Hypersensitivity; Mental Disorders; Parkinsonian Di | 1963 |
[COMPLICATIONS OF NEUROLEPTICS].
Topics: Antipsychotic Agents; Chlorpromazine; Haloperidol; Parkinsonian Disorders; Phenothiazines; Prochlorp | 1963 |
[EXTRAPYRAMIDAL SYMPTOMS DUE TO THE USE OF PSYCHOPHARMACA].
Topics: Chlorpromazine; Chlorprothixene; Extrapyramidal Tracts; Fluphenazine; Imipramine; Methotrimeprazine; | 1963 |
AN EXPERIMENTAL STUDY OF THE NEUROPATHOLOGICAL AND TOXICOLOGICAL EFFECTS OF CHLORPROMAZINE AND RESERPINE.
Topics: Cerebellum; Cerebrovascular Circulation; Chlorpromazine; Guinea Pigs; Nervous System Diseases; Parki | 1964 |
DRUG-INDUCED PARKINSONIAN SYNDROME IN A CASE OF TRANQUILLIZER POISONING.
Topics: Chlorpromazine; Glutethimide; Humans; Muscle Relaxants, Central; Parasympatholytics; Parkinsonian Di | 1964 |
[HUNTINGTON'S CHOREA, HUMOR DISORDERS WITH MANIC MANIFESTATIONS, BENEFICIAL EFFECTS OF HALOPERIDOL (FLUOROPHENYLPIPERIDINOBUTYROPHENONE). ABSENCE OF THE THERAPEUTIC AKINETO-HYPERTONIC SYNDROME].
Topics: Bipolar Disorder; Chlorpromazine; Chorea; Electroencephalography; Electromyography; Haloperidol; Hum | 1964 |
[NEUROLEPTICS AND THE LAW OF STAGES].
Topics: Antipsychotic Agents; Catalepsy; Catatonia; Chlorpromazine; Epilepsy; Humans; Imipramine; Parkinsoni | 1964 |
[OCULAR PRESSURE, NEUROLEPTIC AGENTS AND PARKINSONIAN STATES].
Topics: Antipsychotic Agents; Chlorpromazine; Haloperidol; Intraocular Pressure; Methotrimeprazine; Parkinso | 1963 |
[ON THE ANTAGONISM OF THE ACTION OF NEUROLEPTICS AND ANTIPARKINSON AGENTS].
Topics: Antiparkinson Agents; Antipsychotic Agents; Chlorpromazine; Handwriting; Humans; Movement Disorders; | 1964 |
NEUROLOGICAL SYMPTOMS WITH PHENOTHIAZINES.
Topics: Brain Diseases; Chlorpromazine; Movement Disorders; Neurologic Manifestations; Parkinsonian Disorder | 1964 |
THE RELATIONSHIP OF THE ALPHA AND GAMMA MOTOR SYSTEMS TO THE EFFICACY OF THE SURGICAL THERAPY OF PARKINSONISM.
Topics: Brain; Chlorpromazine; Globus Pallidus; Humans; Movement Disorders; Neurosurgery; Parkinsonian Disor | 1963 |
AN APPARENTLY IRREVERSIBLE SYNDROME OF ABNORMAL MOVEMENTS FOLLOWING PHENOTHIAZINE MEDICATION.
Topics: Brain; Brain Damage, Chronic; Brain Diseases; Chlorpromazine; Chorea; Diagnosis, Differential; Elect | 1964 |
MODIFICATION BY DRUGS OF THE METABOLISM OF 3,4-DIHYDROXYPHENYLETHYLAMINE, NORADRENALINE AND 5-HYDROXYTRYPTAMINE IN THE BRAIN.
Topics: Animals; Atropine; Behavior, Animal; Brain; Brain Chemistry; Cats; Caudate Nucleus; Cerebral Cortex; | 1965 |
[Occurrence and interpretation of psychomotor parkinsonism in megaphen or largactil prolonged therapy].
Topics: Chlorpromazine; Parkinson Disease; Parkinsonian Disorders | 1954 |
[Parkinsonian syndrome following prolonged administration of chlorpromazine with fatal concomitant stroke. Appearance of pallidal lesions].
Topics: Basal Ganglia; Chlorpromazine; Ganglia; Globus Pallidus; Humans; Parkinson Disease; Parkinsonian Dis | 1959 |