chlorpromazine has been researched along with Parkinson Disease in 87 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The anti-tremor potency of the compounds was assessed from suppression of Tremorine-induced tremors in mice." | 7.64 | Relationship between anti-acetylcholine and anti-Tremorine activity in anti-parkinsonian and related drugs. ( AHMED, A; MARSHALL, PB, 1962) |
| " The anti-tremor potency of the compounds was assessed from suppression of Tremorine-induced tremors in mice." | 3.64 | Relationship between anti-acetylcholine and anti-Tremorine activity in anti-parkinsonian and related drugs. ( AHMED, A; MARSHALL, PB, 1962) |
| "However, the performances of Huntington's disease subjects appeared to be different when compared to the other two groups." | 2.69 | Kinematic analysis of the reach to grasp movement in Parkinson's and Huntington's disease subjects. ( Bonfiglioli, C; Castiello, U; De Berti, G; Nichelli, P; Nicoletti, R, 1998) |
| "(ii) The effect of schizophrenia is to increase MAE duration, and this is not due to some peripheral artefact." | 2.39 | The duration of the movement aftereffect as an index of psychiatric illness. ( Harris, J, 1994) |
| "While neurodegenerative diseases affect millions of patients worldwide, there are insufficient available therapeutics to halt or slow down the progression of these diseases." | 1.72 | Design, Synthesis, and Biological Evaluation of Potent 20S Proteasome Activators for the Potential Treatment of α-Synucleinopathies. ( Jones, CL; Staerz, SD; Tepe, JJ, 2022) |
| "In addition to the diagnosis of chronic pseudoakathisia, five patients (62." | 1.31 | Prevalence and characteristics of patients with pseudoakathisia. ( Christodoulou, GN; Havaki-Kontaxaki, BJ; Kontaxakis, VP, 2000) |
| "Levodopa-induced dyskinesias (LID) in Parkinson's disease (PD) may be classified into three main categories: "On" dyskinesias, diphasic dyskinesias (DD), and "off" periods." | 1.28 | Levodopa-induced dyskinesias in Parkinson's disease: clinical and pharmacological classification. ( Gershanik, O; Luquin, MR; Obeso, JA; Scipioni, O; Vaamonde, J, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 79 (90.80) | 18.7374 |
| 1990's | 4 (4.60) | 18.2507 |
| 2000's | 1 (1.15) | 29.6817 |
| 2010's | 2 (2.30) | 24.3611 |
| 2020's | 1 (1.15) | 2.80 |
| Authors | Studies |
|---|---|
| Staerz, SD | 1 |
| Jones, CL | 1 |
| Tepe, JJ | 1 |
| Rukmangathen, R | 1 |
| Yallamalli, IM | 1 |
| Yalavarthi, PR | 1 |
| Lv, H | 1 |
| Yu, F | 1 |
| Sha, C | 1 |
| Huang, Y | 1 |
| Lu, Y | 1 |
| Zhang, L | 1 |
| Zhai, R | 1 |
| Wang, T | 1 |
| Fu, F | 1 |
| BALESTRIERI, A | 1 |
| MONTANARI, M | 1 |
| BERGOUIGNAN, M | 1 |
| DE BOUCAUD, P | 1 |
| FOURNIAL, P | 1 |
| BENTE, D | 1 |
| ITIL, T | 1 |
| MEGGIO, B | 1 |
| CATTANI, F | 1 |
| HAASE, HJ | 3 |
| MAY, RH | 1 |
| VOEGELE, GE | 1 |
| FREYHAN, FA | 4 |
| SOMOGYI, I | 1 |
| TASS, G | 1 |
| NAHUNEK, K | 1 |
| RYBAKOVA, V | 1 |
| HASKOVEC, L | 1 |
| KNAUF, HW | 1 |
| LIT, AC | 1 |
| CAHAN, RB | 1 |
| PARRISH, DD | 1 |
| GUGGENHEIM, P | 1 |
| COHEN, L | 1 |
| GOLDSCHMIDT, D | 1 |
| AHMED, A | 1 |
| MARSHALL, PB | 1 |
| DI PERRI, R | 2 |
| GIAQUINTO, S | 1 |
| MERIAUX, J | 1 |
| NAVARRANNE, P | 1 |
| STRATAS, NE | 1 |
| PHILLIPS, RD | 1 |
| WALKER, PA | 1 |
| SANDIFER, MG | 1 |
| MANGHI, E | 1 |
| FLUGEL, F | 1 |
| POURSINES, Y | 1 |
| ALLIEZ, J | 1 |
| TOGA, M | 1 |
| Sheppard, C | 1 |
| Merlis, S | 1 |
| Rajput, AH | 1 |
| Rozdilsky, B | 1 |
| Hornykiewicz, O | 1 |
| Shannak, K | 1 |
| Lee, T | 1 |
| Seeman, P | 1 |
| Barbosa, ER | 1 |
| Marchiori, PE | 1 |
| Scaff, M | 1 |
| de Assis, JL | 1 |
| Young, SN | 1 |
| Gauthier, S | 1 |
| Chouinard, G | 1 |
| Anderson, GM | 1 |
| Purdy, WC | 1 |
| Atadzhanov, M | 1 |
| Campbell, DJ | 1 |
| Mendelsohn, FA | 1 |
| Adam, WR | 1 |
| Funder, JW | 1 |
| Harris, J | 1 |
| Gorchein, A | 1 |
| Bonfiglioli, C | 1 |
| De Berti, G | 1 |
| Nichelli, P | 1 |
| Nicoletti, R | 1 |
| Castiello, U | 1 |
| Havaki-Kontaxaki, BJ | 1 |
| Kontaxakis, VP | 1 |
| Christodoulou, GN | 1 |
| Hebenstreit, G | 1 |
| Nagatsu, T | 1 |
| Kanamori, T | 1 |
| Kato, T | 1 |
| Iizuka, R | 1 |
| Narabayashi, H | 1 |
| Martin, IC | 1 |
| Stadler, H | 1 |
| Ciria, MG | 1 |
| Bartholini, G | 2 |
| Beasley, BA | 1 |
| Ford, DH | 1 |
| Duvoisin, RC | 2 |
| Pakszys, W | 1 |
| Paulson, GW | 1 |
| Rizvi, CA | 1 |
| Crane, GE | 1 |
| Arushanian, EB | 2 |
| Luquin, MR | 1 |
| Scipioni, O | 1 |
| Vaamonde, J | 1 |
| Gershanik, O | 1 |
| Obeso, JA | 1 |
| Poirier, LJ | 1 |
| Stern, J | 1 |
| Mendell, J | 1 |
| Clark, K | 1 |
| Vogt, M | 1 |
| Carlsson, A | 1 |
| Van Loon, GR | 1 |
| Bruck, H | 1 |
| Gerstenbrand, F | 1 |
| Gnad, H | 1 |
| Gründig, E | 1 |
| Prosenz, P | 1 |
| Turunen, S | 1 |
| Achté, KA | 1 |
| Klawans, HL | 1 |
| Jurna, I | 1 |
| Nell, T | 1 |
| Schreyer, I | 1 |
| Sourkes, TL | 1 |
| Pakkenberg, H | 1 |
| Bottcher, J | 1 |
| Proctor, P | 1 |
| McGinness, J | 1 |
| Corry, P | 1 |
| McClelland, HA | 1 |
| Blessed, G | 1 |
| Bhate, S | 1 |
| Ali, N | 1 |
| Clarke, PA | 1 |
| Kelly, JT | 1 |
| Zimmermann, RL | 1 |
| Abuzzahab, FS | 1 |
| Schiele, BC | 1 |
| Singh, P | 2 |
| McDevitt, D | 1 |
| Mackay, J | 2 |
| Hadden, DR | 2 |
| Thody, AJ | 1 |
| Shuster, S | 1 |
| Messiha, FS | 1 |
| Turek, I | 1 |
| Morrison, AB | 1 |
| Webster, RA | 1 |
| McDevitt, DG | 1 |
| Ambani, LM | 1 |
| Van Woert, MH | 1 |
| Bowers, MB | 1 |
| Marsden, CD | 1 |
| Ganev, G | 1 |
| Karamalakov, L | 1 |
| Milenkov, K | 1 |
| Ianachkova, M | 1 |
| Sakhatchieva, L | 1 |
| Kiuchukova, P | 1 |
| Roĭlev, I | 1 |
| Naumov, I | 1 |
| Cheshmedzhiev, P | 1 |
| Dochkov, Zh | 1 |
| Brindle, GF | 1 |
| Jones, AB | 1 |
| Pare, CM | 2 |
| Nicholson, WJ | 1 |
| Price, K | 1 |
| Stacey, RS | 1 |
| Steg, G | 1 |
| Roos, BE | 1 |
| Blum, B | 1 |
| Weizmann, H | 1 |
| Simpson, GM | 1 |
| Krasilowsky, D | 1 |
| Kulcsar, IS | 1 |
| Merskey, H | 1 |
| Bruno, A | 1 |
| Bruno, SC | 1 |
| Chase, TN | 1 |
| Schnur, JA | 1 |
| Gordon, EK | 1 |
| Tissot, R | 1 |
| Culebras, A | 1 |
| Ialdygina, AS | 1 |
| Pervomaĭskiĭ, BIa | 1 |
| Antropov, IuA | 1 |
| Hader, M | 1 |
| Puca, FM | 1 |
| Oehme, P | 1 |
| Schwarz, K | 1 |
| Ekdawi, MY | 1 |
| Fowke, R | 1 |
11 reviews available for chlorpromazine and Parkinson Disease
| Article | Year |
|---|---|
[Modeling parkinsonism (review)].
Topics: Aluminum; Animals; Carbachol; Cats; Caudate Nucleus; Chlorides; Chlorpromazine; Disease Models, Anim | 1982 |
Is aldosterone secretion under dopaminergic control?
Topics: Aldosterone; Bromocriptine; Chlorpromazine; Dopamine; Dopamine Antagonists; Edema; Humans; Levodopa; | 1981 |
The duration of the movement aftereffect as an index of psychiatric illness.
Topics: Adult; Antiparkinson Agents; Attention; Chlorpromazine; Dopamine; Eye Movements; Female; Fixation, O | 1994 |
[The use of psychotropic drugs in general practice].
Topics: Alcohol Withdrawal Delirium; Anti-Anxiety Agents; Anxiety; Benzhydryl Compounds; Benzodiazepines; Bi | 1977 |
Aging and the extrapyramidal system.
Topics: Aged; Aging; Basal Ganglia Diseases; Chlorpromazine; Chorea; Dopamine; Frontal Lobe; Gait; Haloperid | 1976 |
Nervous mechanisms involved in experimentally induced extrapyramidal disturbances.
Topics: Animals; Basal Ganglia Diseases; Benztropine; Brain; Cats; Caudate Nucleus; Cerebellar Nuclei; Chlor | 1974 |
Release from brain tissue of compounds with possible transmitter function: interaction of drugs with these substances.
Topics: Acetylcholine; Animals; Brain; Brain Chemistry; Chlorpromazine; Dopamine; Humans; Norepinephrine; Pa | 1969 |
[The role of dopamine in the physiology and pathology of the basal ganglia].
Topics: Basal Ganglia; Brain; Caudate Nucleus; Chlorpromazine; Corpus Striatum; Dihydroxyphenylalanine; Dopa | 1972 |
Biochemical and pharmacological aspects of Parkinsonism.
Topics: Animals; Blood-Brain Barrier; Brain; Central Nervous System; Chemoreceptor Cells; Chlorpromazine; Co | 1972 |
The role of brain catecholamines in the regulation of ACTH secretion.
Topics: 17-Hydroxycorticosteroids; Acetylcholine; Adrenal Cortex Hormones; Adrenal Glands; Adrenalectomy; Ad | 1974 |
The pharmacology of parkinsonism (a review).
Topics: Acetylcholine; Animals; Atropa belladonna; Atropine; Central Nervous System; Chlorpromazine; Dextroa | 1968 |
9 trials available for chlorpromazine and Parkinson Disease
| Article | Year |
|---|---|
Kinematic analysis of the reach to grasp movement in Parkinson's and Huntington's disease subjects.
Topics: Adult; Age of Onset; Aged; Analysis of Variance; Antiparkinson Agents; Basal Ganglia; Chlorpromazine | 1998 |
Implications of phenothiazine side effects: a study of antiparkinsonian agents in an older population.
Topics: Adult; Aged; Antipsychotic Agents; Chlorpromazine; Clinical Trials as Topic; Delayed-Action Preparat | 1975 |
Tardive dyskinesia as a possible sequel of long-term therapy with phenothiazines.
Topics: Adolescent; Child; Chlorpromazine; Clinical Trials as Topic; Diagnosis, Differential; Dystonia Muscu | 1975 |
The abrupt withdrawal of antiparkinsonian drugs in schizophrenic patients.
Topics: Adult; Aged; Antiparkinson Agents; Basal Ganglia Diseases; Behavior; Chlorpromazine; Clinical Trials | 1974 |
A double-blind study of amantadine hydrochloride versus benztropine mesylate in drug-induced parkinsonism.
Topics: Administration, Oral; Amantadine; Antiparkinson Agents; Benztropine; Capsules; Chlorpromazine; Clini | 1974 |
[Prophylaxis of neuroleptic parkonsonism with the Bulgarian drug INKhA-17 (Paabainkh) and bellazon].
Topics: Bulgaria; Chlorpromazine; Clinical Trials as Topic; Humans; Isoniazid; Mental Disorders; Parasympath | 1968 |
Brain amine concentrations after monoamine oxidase inhibitor administration.
Topics: Aged; Alkynes; Autopsy; Brain; Brain Stem; Caudate Nucleus; Chlorpromazine; Dopamine; Humans; Hypoth | 1972 |
Harmine antagonism of drug-induced extra-pyramidal disturbances.
Topics: Alkaloids; Anticonvulsants; Chlorpromazine; Clinical Trials as Topic; Encephalitis; Female; Humans; | 1964 |
Effects of L-DOPA on pharmacological parkinsonism.
Topics: Adolescent; Adult; Chlorpromazine; Clinical Trials as Topic; Dihydroxyphenylalanine; Female; Haloper | 1966 |
67 other studies available for chlorpromazine and Parkinson Disease
| Article | Year |
|---|---|
Design, Synthesis, and Biological Evaluation of Potent 20S Proteasome Activators for the Potential Treatment of α-Synucleinopathies.
Topics: alpha-Synuclein; Animals; Humans; Intrinsically Disordered Proteins; Mammals; Neurodegenerative Dise | 2022 |
Biopharmaceutical Potential of Selegiline Loaded Chitosan Nanoparticles in the Management of Parkinson's Disease.
Topics: Administration, Intranasal; Animals; Antiparkinson Agents; Brain; Catalase; Catalepsy; Chitosan; Chl | 2019 |
Effects of rotigotine and rotigotine extended-release microsphere therapy on myocardial ischemic injury in mice.
Topics: Animals; Cardiotonic Agents; Chlorpromazine; Creatine Kinase, MB Form; Dopamine Agonists; Isoprotere | 2019 |
[Effect of largactil in parkinson syndrome].
Topics: Autonomic Agents; Chlorpromazine; Parkinson Disease | 1953 |
[Reversible parkinsonism in the course of largactil therapy of vomiting in pregnancy].
Topics: Chlorpromazine; Female; Parkinson Disease; Parkinsonian Disorders; Pregnancy; Pregnancy Complication | 1954 |
[Parkinsonian states appearing during chlorpromazine therapy].
Topics: Chlorpromazine; Parkinson Disease | 1954 |
[The effects of high-dosed reserpin (serpasil) treatment and drug-induced parkinsonism-like states on the electroencephalogram].
Topics: Antihypertensive Agents; Chlorpromazine; Electroencephalography; Humans; Parkinson Disease; Parkinso | 1955 |
[Hypothesis on the mechanism of action of chlorpromazine (largactil) on the extrapyramidal manifestations of the parkinsonian syndrome].
Topics: Chlorpromazine; Parkinson Disease; Parkinsonian Disorders | 1955 |
[Psychiatric experiences with megaphen (largactil) and the Rauwolfia alkaloid serpasil with special reference to Parkinson's psychomotor syndrome].
Topics: Antihypertensive Agents; Chlorpromazine; Parkinson Disease; Rauwolfia; Reserpine; Schizophrenia; Sec | 1955 |
Parkinsonian reactions following chlorpromazine and reserpine; similar reactions in the same patients.
Topics: Antihypertensive Agents; Chlorpromazine; Parkinson Disease; Reserpine; Secologanin Tryptamine Alkalo | 1956 |
[Definition and mode of action of the psychomotor Parkinson syndrome therapeutically induced by serpasil and largactil].
Topics: Antihypertensive Agents; Chlorpromazine; Parkinson Disease; Reserpine; Secologanin Tryptamine Alkalo | 1956 |
Comments on the biological and psychopathological basis of individual variation in chlorpromazine therapy.
Topics: Chlorpromazine; Humans; Parkinson Disease; Psychopathology | 1956 |
Comments on the biological and psychopathological basis of individual variation in chlorpromazine therapy.
Topics: Chlorpromazine; Humans; Parkinson Disease; Psychopathology | 1956 |
Comments on the biological and psychopathological basis of individual variation in chlorpromazine therapy.
Topics: Chlorpromazine; Humans; Parkinson Disease; Psychopathology | 1956 |
Comments on the biological and psychopathological basis of individual variation in chlorpromazine therapy.
Topics: Chlorpromazine; Humans; Parkinson Disease; Psychopathology | 1956 |
Psychomotility and parkinsonism in treatment with neuroleptic drugs.
Topics: Antipsychotic Agents; Chlorpromazine; Electroconvulsive Therapy; Humans; Mental Disorders; Movement; | 1957 |
[BAL therapy in Parkinson's syndrome caused by largactil].
Topics: Chlorpromazine; Dimercaprol; Parkinson Disease | 1957 |
[Psychomotility, extrapyramidal syndrome and mode of action of neuroleptic therapies; chlorpromazine, reserpine and prochlorperazine].
Topics: Antipsychotic Agents; Basal Ganglia Diseases; Chlorpromazine; Disease; Extrapyramidal Tracts; Humans | 1957 |
[Parkinsonism-like symptoms caused by chlorpromazine therapy].
Topics: Chlorpromazine; Electroconvulsive Therapy; Humans; Parkinson Disease; Parkinsonian Disorders; Psycho | 1958 |
[Contribution to the parkinsonian effects of chlorpromazine & reserpine].
Topics: Chlorpromazine; Humans; Parkinson Disease; Reserpine | 1958 |
[Treatment of parkinsonism-like syndromes caused by reserpine & chlorpromazine].
Topics: Chlorpromazine; Humans; Parkinson Disease; Parkinsonian Disorders; Piperidines; Reserpine; Syndrome | 1958 |
[Parkinson's disease treated with neuroleptics].
Topics: Antihypertensive Agents; Antipsychotic Agents; Chlorpromazine; Parkinson Disease; Secologanin Trypta | 1959 |
Reversibility of drug-induced parkinsonism.
Topics: Chlorpromazine; Parkinson Disease; Parkinsonian Disorders; Reserpine | 1960 |
Theoretical considerations in parkinsonism induced by tranquilizing drugs.
Topics: Chlorpromazine; Parkinson Disease; Parkinsonian Disorders; Reserpine; Tranquilizing Agents | 1959 |
[Experiences and conclusions in regard to the use of hirepin. Part I].
Topics: Chlorpromazine; Parkinson Disease; Perphenazine; Reserpine | 1960 |
Relationship between anti-acetylcholine and anti-Tremorine activity in anti-parkinsonian and related drugs.
Topics: Acetylcholine; Animals; Antiparkinson Agents; Antipsychotic Agents; Chlorpromazine; Cholinergic Anta | 1962 |
[Chlorpromazine, Jendrassi's maneuver and parkinsonian rigor].
Topics: Chlorpromazine; Electroencephalography; Electromyography; Muscle Rigidity; Nervous System Physiologi | 1962 |
[Paradoxical parkinsonian syndrome after drug ingestion in a patient with portacaval anastomosis].
Topics: Chlorpromazine; Parkinson Disease; Parkinsonian Disorders; Portacaval Shunt, Surgical | 1963 |
A study of drug-induced parkinsonism.
Topics: Chlorpromazine; Humans; Mental Disorders; Parkinson Disease; Parkinsonian Disorders; Prochlorperazin | 1963 |
[Occurrence and interpretation of psychomotor parkinsonism in megaphen or largactil prolonged therapy].
Topics: Chlorpromazine; Parkinson Disease; Parkinsonian Disorders | 1954 |
[Largactil (R.P.4560) in hypertonic and dyskinetic syndromes].
Topics: Chlorpromazine; Chorea; Dyskinesias; Humans; Movement Disorders; Parkinson Disease; Syndrome | 1954 |
[Parkinson like manifestations produced by medicamentation].
Topics: Antihypertensive Agents; Chlorpromazine; Humans; Parkinson Disease; Secologanin Tryptamine Alkaloids | 1955 |
[Parkinsonian syndrome following prolonged administration of chlorpromazine with fatal concomitant stroke. Appearance of pallidal lesions].
Topics: Basal Ganglia; Chlorpromazine; Ganglia; Globus Pallidus; Humans; Parkinson Disease; Parkinsonian Dis | 1959 |
Drug-induced extrapyramidal symptoms: their incidence and treatment.
Topics: Chlorpromazine; Chlorprothixene; Extrapyramidal Tracts; Female; Fluphenazine; Humans; Male; Parasymp | 1967 |
Reversible drug-induced parkinsonism. Clinicopathologic study of two cases.
Topics: Aged; Antipsychotic Agents; Chlorpromazine; Haloperidol; Humans; Male; Middle Aged; Parkinson Diseas | 1982 |
[Huntington chorea: report of 16 cases].
Topics: Adult; Aged; Brain Diseases; Chlorpromazine; Dementia; Diagnosis, Differential; Female; gamma-Aminob | 1983 |
The effect of carbidopa and benserazide on human plasma 5-hydroxytryptophan levels.
Topics: 5-Hydroxytryptophan; Adult; Benserazide; Carbidopa; Chlorpromazine; Dihydroxyphenylalanine; Humans; | 1982 |
Treatment of Parkinson's disease in a patient with acute intermittent porphyria.
Topics: Aged; Antiparkinson Agents; Benserazide; Chlorpromazine; Dopamine Antagonists; Drug Interactions; Fe | 1995 |
Prevalence and characteristics of patients with pseudoakathisia.
Topics: Adult; Akathisia, Drug-Induced; Antiparkinson Agents; Antipsychotic Agents; Chlorpromazine; Chronic | 2000 |
Dopamine-stimulated adenylate cyclase activity in the human brain: changes in Parkinsonism.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Aged; Brain; Caudate Nucleus; Chlorpromazine; Dopamine; F | 1978 |
"In vivo" release of endogenous neurotransmitters in cat limbic regions: effect of chlorpromazine and of electrical stimulation.
Topics: Acetylcholine; Animals; Cats; Chlorpromazine; Dopamine; Electric Stimulation; Female; Hippocampus; L | 1975 |
Parkinsonism: animal analogues of the human disorder.
Topics: Animals; Butyrophenones; Chlorpromazine; Disease Models, Animal; Haplorhini; Hydroxydopamines; Levod | 1976 |
[Interaction between L-dopa and other drugs].
Topics: Amantadine; Anti-Arrhythmia Agents; Apomorphine; Chlorpromazine; Drug Antagonism; Drug Interactions; | 1976 |
[The phenomenon of experimental motor retardation as one of the manifestations of the Parkinsonian syndrome].
Topics: Amphetamine; Animals; Catecholamines; Cats; Caudate Nucleus; Chlorpromazine; Dihydroergotoxine; Dise | 1975 |
Levodopa-induced dyskinesias in Parkinson's disease: clinical and pharmacological classification.
Topics: Aged; Apomorphine; Chlorpromazine; Dopamine Agents; Dose-Response Relationship, Drug; Dyskinesia, Dr | 1992 |
H reflex suppression by thalamic stimulation and drug administration.
Topics: Chlorpromazine; Diazepam; Electric Stimulation; Humans; Motor Neurons; Muscle Spindles; Oscillometry | 1968 |
[Comparative biochemical studies in organic parkinsonian syndromes and drug induced parkinsonian syndromes].
Topics: Alanine Transaminase; Aspartate Aminotransferases; Biochemical Phenomena; Biochemistry; Chlorpromazi | 1966 |
The bucco-linguo-masticatory syndrome as a side-effect of neuroleptics therapy.
Topics: Adult; Aged; Brain Damage, Chronic; Cheek; Chlorpromazine; Chlorprothixene; Clopenthixol; Female; Ha | 1967 |
Motor disturbance induced by tremorine and oxotremorine.
Topics: Acetylcholine; Amines; Animals; Atropine; Biperiden; Brain; Bridged-Ring Compounds; Chlorpromazine; | 1970 |
Actions of levodopa and dopamine in the central nervous system.
Topics: Animals; Apomorphine; Binding Sites; Brain; Central Nervous System; Chlorpromazine; Dihydroxyphenyla | 1971 |
Corpus striatum in paralysis agitans and in perphenazine-injected rats.
Topics: Aged; Amphetamine; Amphetamines; Animals; Basal Ganglia; Caudate Nucleus; Chlorpromazine; Corpus Str | 1974 |
A hypothesis on the preferential destruction of melanized tissues.
Topics: Cell Survival; Chlorpromazine; DNA; Dwarfism; Ear, Inner; Energy Transfer; Humans; Hypogonadism; Mel | 1974 |
The pharmacological control of growth hormone release. Studies on the action of L-dopa and chlorpromazine in normal subjects and patients with Parkinsonism, acromegaly and delayed onset of puberty.
Topics: Acromegaly; Chlorpromazine; Dihydroxyphenylalanine; Glucose Tolerance Test; Growth Hormone; Humans; | 1973 |
The control of melanocyte-stimulating hormone secretion.
Topics: Animals; Brain; Catecholamines; Chlorpromazine; Dihydroxyphenylalanine; Humans; Hypothalamus; Inject | 1973 |
Decreased dopamine and homovanillic acid excretion in a case with chlorpromazine-induced Parkinsonism.
Topics: Chlorpromazine; Dopamine; Homovanillic Acid; Humans; Male; Parkinson Disease; Parkinson Disease, Sec | 1973 |
Drug-induced experimental Parkinsonism.
Topics: Animals; Atropine; Benztropine; Butyrophenones; Cats; Chlorpromazine; Dose-Response Relationship, Dr | 1973 |
Effects of L-dopa and chlorpromazine on human growth hormone and TSH secretion in normal subjects and acromegalics.
Topics: Acromegaly; Adult; Chlorpromazine; Dihydroxyphenylalanine; Female; Glucose; Growth Hormone; Humans; | 1973 |
Physostigmine effects on phenothiazine-induced extrapyramidal reactions.
Topics: Adult; Antiparkinson Agents; Chlorpromazine; Drug Hypersensitivity; Extrapyramidal Tracts; Female; H | 1973 |
Reversal of reserpine-induced bradykinesia by alpha-methyldopa--new light on its modus operandi.
Topics: Animals; Carbidopa; Chlorpromazine; Dihydroxyphenylalanine; Disease Models, Animal; Disulfiram; Dose | 1974 |
The use of neuroleptic agents in a neurosurgical unit.
Topics: Benperidol; Cerebral Angiography; Chlorpromazine; Craniocerebral Trauma; Electrodes; Epilepsy; Fenta | 1969 |
Clinical implications of monoamine oxidase inhibition.
Topics: Brain; Brain Stem; Caudate Nucleus; Chlorpromazine; Depression; Dopamine; Drug Synergism; Humans; Hy | 1972 |
The effect of drugs inducing Parkinson's syndrome on muscle reflex mechanisms. A summary.
Topics: Animals; Chlorpromazine; Electrophysiology; Motor Neurons; Muscles; Parkinson Disease; Phenoxybenzam | 1965 |
Cerebrospinal fluid monoamine catabolites in drug-induced extrapyramidal disorders.
Topics: Amines; Brain; Chlorpromazine; Extrapyramidal Tracts; Female; Humans; Hydroxyindoleacetic Acid; Move | 1970 |
[Pharmaco-biochemical mechanisms and modern therapy in Parkinsonian syndromes].
Topics: Animals; Central Nervous System; Chlorpromazine; Dihydroxyphenylalanine; Dopamine; Extrapyramidal Tr | 1970 |
More on tick bite in Parkinson's disease.
Topics: Animals; Chlorpromazine; Dogs; Humans; Motor Activity; Parkinson Disease; Peripheral Nerves; Tick To | 1971 |
[On the clinical picture of current forms of epidemic encephalitis].
Topics: Adolescent; Adult; Autonomic Nervous System; Child; Chlorpromazine; Depersonalization; Encephalitis, | 1968 |
Antiparkinsonism medication for the phenothiazine-induced pyramidal-extrapyramidal syndrome in elderly brain-damaged patients.
Topics: Aged; Brain Damage, Chronic; Chlorpromazine; Female; Humans; Male; Parkinson Disease; Perphenazine; | 1965 |
[Comparative analysis of mechanical and electrical monosynaptic reflexes in patients with Parkinson's disease in various experimental conditions].
Topics: Chlorpromazine; Humans; Parkinson Disease; Phenothiazines; Reflex | 1964 |
[Etiology and therapy of Parkinson's syndrome and related pharmacological concepts shown in experimental models].
Topics: Animals; Brain Chemistry; Chlorpromazine; Dihydroxyphenylalanine; Dopamine; Humans; Hypothermia; Mic | 1966 |
A controlled trial of anti-Parkinson drugs in drug-induced Parkinsonism.
Topics: Adolescent; Adult; Chlorpromazine; Haloperidol; Humans; Middle Aged; Orphenadrine; Parasympatholytic | 1966 |