chlorpromazine has been researched along with Pancreatitis in 13 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Pancreatitis: INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A nondiabetic young male patient in hypomanic phase of bipolar disorder on maintenance treatment with sodium valproate, developed transient episode of acute pancreatitis and diabetic ketoacidosis after addition of chlorpromazine and halopridol." | 7.72 | Acute pancreatitis and diabetic ketoacidosis in non-diabetic person while on treatment with sodium valproate, chlorpromazine and haloperidol. ( Gupta, SB; Laghate, VD, 2004) |
| "Acute pancreatitis was induced in 20 piglets." | 5.26 | Chlorpromazine treatment of experimental acute fulminant pancreatitis in pigs. ( Kinnunen, PK; Lempinen, M; Nordling, S; Schröder, T, 1981) |
| "A nondiabetic young male patient in hypomanic phase of bipolar disorder on maintenance treatment with sodium valproate, developed transient episode of acute pancreatitis and diabetic ketoacidosis after addition of chlorpromazine and halopridol." | 3.72 | Acute pancreatitis and diabetic ketoacidosis in non-diabetic person while on treatment with sodium valproate, chlorpromazine and haloperidol. ( Gupta, SB; Laghate, VD, 2004) |
| "In mongrel dogs with induced pancreatitis we studied the effects of the nonspecific phospholipase A2-inhibitors chlorpromazine, gabexate mesilate and CaNa2EDTA on the course of pancreatogenic shock and the intrapancreatic lysolecithin production." | 3.67 | [Phospholipase A2 inhibitors in hemorrhagic-necrotizing pancreatitis. Animal experiment evaluation of a new treatment concept]. ( Alles, JU; Kahle, M; Klein, U; König, W; Martin, U, 1985) |
| "Acute pancreatitis was induced in 20 piglets." | 1.26 | Chlorpromazine treatment of experimental acute fulminant pancreatitis in pigs. ( Kinnunen, PK; Lempinen, M; Nordling, S; Schröder, T, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (69.23) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| de Arriba Méndez, JJ | 1 |
| TSUKUYAMA, Y | 1 |
| RIKHY, SS | 1 |
| SINGH, JP | 1 |
| MISRA, P | 1 |
| BALASUNDARAM, S | 1 |
| CACHIN, M | 1 |
| RICHARDS, W | 1 |
| PATRICK, JR | 1 |
| Laghate, VD | 1 |
| Gupta, SB | 1 |
| Schröder, T | 2 |
| Lempinen, M | 1 |
| Nordling, S | 1 |
| Kinnunen, PK | 1 |
| Mäkelä, A | 1 |
| Kuusi, T | 1 |
| Saĭdalikhodzhaeva, OZ | 1 |
| Iuldashev, NM | 1 |
| Daniiarov, AN | 1 |
| Muratova, UZ | 1 |
| Kahle, M | 2 |
| König, H | 1 |
| Filler, RD | 1 |
| Klein, U | 1 |
| König, W | 1 |
| Martin, U | 1 |
| Alles, JU | 1 |
| Loeb, FX | 1 |
| King, TL | 1 |
| Ankudinov, FS | 1 |
| Zhits, NZ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Single Center, Randomized, Double-Blind Controlled Study of Topical Endoluminal Pancreatic Duct Lidocaine for Prevention of Post-ERCP Pancreatitis[NCT00953199] | 506 participants (Actual) | Interventional | 2010-03-31 | Completed | |||
| A Randomized Controlled Trial of IV Ketorolac to Prevent Post-ERCP Pancreatitis[NCT02465138] | Phase 4 | 0 participants (Actual) | Interventional | 2023-11-30 | Withdrawn (stopped due to Lack of Funding) | ||
| Effects of High Intra-procedural Oxygen Fraction on Post-ERCP Pancreatitis: A Randomized Clinical Trial[NCT04876768] | 25 participants (Actual) | Interventional | 2021-05-18 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The primary outcome of interest will be development of acute pancreatitis defined as new or worsening abdominal pain post-ERCP associated with an increase in serum amylase at least 3 times the upper limit of normal. (NCT00953199)
Timeframe: 24-48 hours post-procedure
| Intervention | participants (Number) |
|---|---|
| Lidocaine | 26 |
| Normal Saline | 20 |
serum amylase levels are measure by a blood draw (NCT00953199)
Timeframe: measurement is taken 2 hrs after ERCP
| Intervention | units/liter (Mean) |
|---|---|
| Lidocaine | 130 |
| Normal Saline | 128 |
1 review available for chlorpromazine and Pancreatitis
| Article | Year |
|---|---|
[Dexamethasone-induced hiccup].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Chlorpromazine; Dex | 2016 |
12 other studies available for chlorpromazine and Pancreatitis
| Article | Year |
|---|---|
[Early diagnosis and conservative treatment of pancreatitis].
Topics: Adrenal Cortex Hormones; Chlorpromazine; Diet; Diet Therapy; Early Diagnosis; Humans; Pancreatitis; | 1963 |
MUMPS PANCREATITIS; A CASE REPORT.
Topics: Carbohydrates; Cardiovascular Agents; Child; Chlorpromazine; Humans; Meperidine; Mumps; Muscle Relax | 1963 |
[TREATMENT OF ACUTE AND CHRONIC PANCREATITIS].
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antibiotics, Antitubercular; Autonomic Nerve Block; | 1964 |
DEATH FROM ASTHMA IN CHILDREN.
Topics: Adolescent; Adrenal Cortex Hormones; Aminophylline; Asthma; California; Child; Chlorpromazine; Death | 1965 |
Acute pancreatitis and diabetic ketoacidosis in non-diabetic person while on treatment with sodium valproate, chlorpromazine and haloperidol.
Topics: Acute Disease; Adult; Antimanic Agents; Bipolar Disorder; Chlorpromazine; Diabetic Ketoacidosis; Dia | 2004 |
Chlorpromazine treatment of experimental acute fulminant pancreatitis in pigs.
Topics: Acute Disease; Animals; Chlorpromazine; Lung; Pancreas; Pancreatitis; Phospholipases A; Phospholipas | 1981 |
Inhibition of serum phospholipase-A2 in acute pancreatitis by pharmacological agents in vitro.
Topics: Acute Disease; Adrenergic beta-Antagonists; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Ste | 1997 |
Inhibition of serum phospholipase-A2 in acute pancreatitis by pharmacological agents in vitro.
Topics: Acute Disease; Adrenergic beta-Antagonists; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Ste | 1997 |
Inhibition of serum phospholipase-A2 in acute pancreatitis by pharmacological agents in vitro.
Topics: Acute Disease; Adrenergic beta-Antagonists; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Ste | 1997 |
Inhibition of serum phospholipase-A2 in acute pancreatitis by pharmacological agents in vitro.
Topics: Acute Disease; Adrenergic beta-Antagonists; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Ste | 1997 |
Inhibition of serum phospholipase-A2 in acute pancreatitis by pharmacological agents in vitro.
Topics: Acute Disease; Adrenergic beta-Antagonists; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Ste | 1997 |
Inhibition of serum phospholipase-A2 in acute pancreatitis by pharmacological agents in vitro.
Topics: Acute Disease; Adrenergic beta-Antagonists; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Ste | 1997 |
Inhibition of serum phospholipase-A2 in acute pancreatitis by pharmacological agents in vitro.
Topics: Acute Disease; Adrenergic beta-Antagonists; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Ste | 1997 |
Inhibition of serum phospholipase-A2 in acute pancreatitis by pharmacological agents in vitro.
Topics: Acute Disease; Adrenergic beta-Antagonists; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Ste | 1997 |
Inhibition of serum phospholipase-A2 in acute pancreatitis by pharmacological agents in vitro.
Topics: Acute Disease; Adrenergic beta-Antagonists; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Ste | 1997 |
[Pancreatic enzyme activity in early phases of acute experimental pancreatitis in rats].
Topics: Acute Disease; alpha-Amylases; Animals; Calcium; Calmodulin; Cations, Divalent; Chlorpromazine; Cold | 2002 |
Lysolecithin concentration in pancreatic tissue during therapy with phospholipase A2-inhibitors in acute necrotizing pancreatitis.
Topics: Acute Disease; Animals; Chlorpromazine; Dogs; Dose-Response Relationship, Drug; Edetic Acid; Female; | 1989 |
[Phospholipase A2 inhibitors in hemorrhagic-necrotizing pancreatitis. Animal experiment evaluation of a new treatment concept].
Topics: Acute Disease; Animals; Chlorpromazine; Dogs; Edetic Acid; Female; Gabexate; Guanidines; Hemodynamic | 1985 |
Chronic gastroduodenitis due to laundry bleach.
Topics: Child; Chlorpromazine; Chronic Disease; Clothing; Detergents; Diagnosis, Differential; Duodenal Dise | 1974 |
[Treatment of aucte pancreatiis by gastric hypothermia].
Topics: Acute Disease; Adolescent; Adult; Analgesics; Atropine; Child; Chlorpromazine; Diphenhydramine; Fema | 1968 |