chlorpromazine has been researched along with Ornithine Carbamoyltransferase Deficiency Disease in 1 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Ornithine Carbamoyltransferase Deficiency Disease: An inherited urea cycle disorder associated with deficiency of the enzyme ORNITHINE CARBAMOYLTRANSFERASE, transmitted as an X-linked trait and featuring elevations of amino acids and ammonia in the serum. Clinical features, which are more prominent in males, include seizures, behavioral alterations, episodic vomiting, lethargy, and coma. (Menkes, Textbook of Child Neurology, 5th ed, pp49-50)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Symptoms and clinical presentations of OTC deficiency vary widely according to the remaining activity of the enzyme." | 1.51 | Malnutrition with hypoaminoacidemia in a 22-year-old pregnant patient masking a likely ornithine transcarbamylase deficiency. ( Chartier, M; Cynober, L; Lefrère, B; Neveux, N; Patkaï, J; Ulmann, G, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lefrère, B | 1 |
| Ulmann, G | 1 |
| Chartier, M | 1 |
| Patkaï, J | 1 |
| Cynober, L | 1 |
| Neveux, N | 1 |
1 other study available for chlorpromazine and Ornithine Carbamoyltransferase Deficiency Disease
| Article | Year |
|---|---|
Malnutrition with hypoaminoacidemia in a 22-year-old pregnant patient masking a likely ornithine transcarbamylase deficiency.
Topics: Anti-Bacterial Agents; Antiemetics; Chlorpromazine; DNA Mutational Analysis; Female; Humans; Infant, | 2019 |