chlorpromazine has been researched along with Niemann-Pick Disease in 7 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 3 (42.86) | 18.7374 |
1990's | 2 (28.57) | 18.2507 |
2000's | 1 (14.29) | 29.6817 |
2010's | 1 (14.29) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Lange, Y | 1 |
Ye, J | 1 |
Steck, TL | 1 |
Fox, JT | 1 |
Kane, FJ | 1 |
Maor, I | 1 |
Mandel, H | 1 |
Aviram, M | 1 |
Mikami, T | 1 |
Takahashi, T | 1 |
Ishida, A | 1 |
Minamiya, Y | 1 |
Ida, H | 1 |
Takada, G | 1 |
Masson, M | 1 |
Spezzatti, B | 1 |
Chapman, J | 1 |
Battisti, C | 1 |
Baumann, N | 2 |
Clerici, C | 1 |
Lacronique, J | 1 |
Kemeny, J | 1 |
Albouz, S | 1 |
Le Saux, F | 1 |
Wenger, D | 1 |
Hauw, JJ | 1 |
7 other studies available for chlorpromazine and Niemann-Pick Disease
Article | Year |
---|---|
Activation mobilizes the cholesterol in the late endosomes-lysosomes of Niemann Pick type C cells.
Topics: Androstenes; Biological Transport; Cells, Cultured; Chlorpromazine; Cholesterol; Cholesterol Oxidase | 2012 |
Niemann-Pick's disease manifesting as schizophrenia.
Topics: Adolescent; Chlorpromazine; Diagnosis, Differential; Humans; Male; Niemann-Pick Diseases; Schizophre | 1967 |
Macrophage uptake of oxidized LDL inhibits lysosomal sphingomyelinase, thus causing the accumulation of unesterified cholesterol-sphingomyelin-rich particles in the lysosomes. A possible role for 7-Ketocholesterol.
Topics: Animals; Cell Line; Cell Membrane; Chlorpromazine; Cholesterol; Cholesterol Esters; Humans; Ketochol | 1995 |
Signaling pathway for radiation-induced apoptosis in the lymphoblasts from neuronopathic (type A) and non-neuronopathic (type B) forms of Niemann-Pick disease.
Topics: Amino Acid Substitution; Animals; Apoptosis; Cell Line, Transformed; Child, Preschool; Chlorpromazin | 2002 |
Calmodulin antagonists chlorpromazine and W-7 inhibit exogenous cholesterol esterification and sphingomyelinase activity in human skin fibroblast cultures. Similarities between drug-induced and Niemann-Pick type C lipidoses.
Topics: Calmodulin; Chlorpromazine; Cholesterol; Cholesterol Esters; Depression, Chemical; Fibroblasts; Huma | 1992 |
[Bioclinical conference in pneumology. Hôpital Laënnec. Case n. 4--February 1985. Interstitial pneumopathy associated with pulmonary infiltration by foamy macrophages].
Topics: Adult; Chlorpromazine; Humans; Lung; Macrophages; Male; Niemann-Pick Diseases; Pulmonary Alveoli; Pu | 1986 |
Modifications of sphingomyelin and phosphatidylcholine metabolism by tricyclic antidepressants and phenothiazines.
Topics: Animals; Antidepressive Agents, Tricyclic; Cell Line; Chlorpromazine; Desipramine; Dose-Response Rel | 1986 |