Compounds > chlorpromazine
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chlorpromazine and Nervous System Diseases

chlorpromazine has been researched along with Nervous System Diseases in 36 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Nervous System Diseases: Diseases of the central and peripheral nervous system. This includes disorders of the brain, spinal cord, cranial nerves, peripheral nerves, nerve roots, autonomic nervous system, neuromuscular junction, and muscle.

Research Excerpts

ExcerptRelevanceReference
"A vitamin B12 deficiency is unusual in pregnant women who consume a normal, varied diet."2.37Clinical chemistry of vitamin B12. ( Davis, RE, 1985)
"Symptoms consisted of confusion, extrapyramidal symptoms, and slow-wave EEG disturbances."1.27A case of lithium-chlorpromazine interaction. ( Yassa, R, 1986)

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199035 (97.22)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (2.78)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kale, OE1
Awodele, O1
Ogundare, TF1
Ekor, M1
BUSTAMANTE, M1
GIACOBINI, E1
OSTERMAN, E1
MACGREGOR, JM1
BOON, AA1
LINDQVIST, R1
GADE, EB1
HEINRICH, K1
TURNER, M1
BERARD, E1
TURNER, N1
FRANCO, N1
DELAY, J1
SADOUN, R1
ROPERT, R1
GUIBERT, M1
BENTE, D2
FLUGEL, F2
GIBSON, JW1
BLUESTONE, SS1
LOWMAN, EW1
SHTEINBERG, SM1
WENDE, S1
ZIOLKO, HU1
DONNADIEU, A1
FLORENTIN, M1
FLORENTIN, C1
BARR, MN1
LEVITA, E1
CHAMBLISS, HC1
SARACLI, T1
SCOTT, RB1
NISHIZONO, M1
MACKIEWICZ, J1
GERSHON, S1
TARASOV, GK1
Swett, C2
Rovinskaia, SA1
Revva, LI1
Roĭzin, L1
O'Connor, M1
Johnson, GH1
James, DI1
Hopkin, DA1
Laplane, R1
Vogt, M1
Yassa, R1
Davis, RE1
Swahn, CG1
Debreceni, L1
Tényi, I1
Csete, B1
Csonka-Takács, L1
Vannotti, A1
Hertrich, O1
Zolotnitskii, RI1
Kutsenok, BM1
Gastev, MD1
Yoshida, H1

Reviews

2 reviews available for chlorpromazine and Nervous System Diseases

ArticleYear
[Multifactorial nature of the pathogenesis of pathological reactions observed following the administration of psychotropic drugs].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1980, Volume: 80, Issue:7

    Topics: Animals; Brain; Chemical and Drug Induced Liver Injury; Chlorpromazine; Female; Humans; Liver; Liver

1980
Clinical chemistry of vitamin B12.
    Advances in clinical chemistry, 1985, Volume: 24

    Topics: Absorption; Adult; Alcoholism; Anemia, Pernicious; Ascorbic Acid; Autoantibodies; Biguanides; Biolog

1985

Trials

1 trial available for chlorpromazine and Nervous System Diseases

ArticleYear
Adverse reactions to chlorpromazine in medical patients: a report from the Boston Collaborative Drug Surveillance Program, Boston University Medical Center.
    Current therapeutic research, clinical and experimental, 1975, Volume: 18, Issue:1 pt 2

    Topics: Adult; Aged; Boston; Cardiovascular Diseases; Chemical and Drug Induced Liver Injury; Chlorpromazine

1975

Other Studies

33 other studies available for chlorpromazine and Nervous System Diseases

ArticleYear
Amlodipine, an L-type calcium channel blocker, protects against chlorpromazine-induced neurobehavioural deficits in mice.
    Fundamental & clinical pharmacology, 2017, Volume: 31, Issue:3

    Topics: Amlodipine; Animals; Antioxidants; Bromocriptine; Calcium Channels, L-Type; Catalase; Chlorpromazine

2017
[Artificial hibernation in neurology and psychiatry; results with R.P. 4560 (largactil)].
    Boletin cultural e informativo - Consejo General de Colegios Medicos de Espana, 1954, Volume: 17, Issue:81

    Topics: Chlorpromazine; Hibernation; Mental Disorders; Nervous System Diseases; Neuralgia; Neurology; Psychi

1954
[Neurological disorders due to hibernal therapy].
    Nordisk medicin, 1954, Nov-04, Volume: 52, Issue:45

    Topics: Chlorpromazine; Movement; Movement Disorders; Nervous System Diseases

1954
Largactil; a new psychomotor brake.
    South African journal of clinical science. Suid-Afrikaanse tydskrif vir kliniese wetenskap, 1955, Volume: 5, Issue:4

    Topics: Chlorpromazine; Mental Disorders; Nervous System Diseases; Psychosurgery; Psychotherapy

1955
[Largactil and related remedies in psychiatry and neurology].
    Nederlands tijdschrift voor geneeskunde, 1955, Sep-10, Volume: 99, Issue:37

    Topics: Chlorpromazine; Mental Disorders; Nervous System Diseases; Neurology; Psychiatry

1955
[Comments on chlorpromazine therapy, with special reference to neuropsychiatric cases].
    Svenska lakartidningen, 1955, Sep-23, Volume: 52, Issue:38

    Topics: Chlorpromazine; Electroconvulsive Therapy; Mental Disorders; Nervous System Diseases; Psychotherapy

1955
[The importance of the phenothiazine derivatives for psychiatry and neurology, with special reference to chlorpromazine].
    Fortschritte der Neurologie, Psychiatrie, und ihrer Grenzgebiete, 1955, Volume: 23, Issue:8

    Topics: Chlorpromazine; Mental Disorders; Nervous System Diseases; Neurology; Phenothiazines; Psychiatry

1955
[Electroencephalography, electrodermography and electromyography changes caused by chlorpromazine in humans].
    Electroencephalography and clinical neurophysiology, 1956, Volume: 8, Issue:1

    Topics: Chlorpromazine; Electroencephalography; Electromyography; Galvanic Skin Response; Humans; Nervous Sy

1956
[Case of neurological complications of chlorpromazine therapy; clinical and pathogenic data].
    Annales medico-psychologiques, 1955, Volume: 113, Issue:5

    Topics: Chlorpromazine; Humans; Nervous System Diseases

1955
[Akinetic-abulic syndrome and its importance in pharmacological-psychiatric research].
    Deutsche medizinische Wochenschrift (1946), 1956, Dec-21, Volume: 81, Issue:51

    Topics: Chlorpromazine; Humans; Mental Disorders; Nervous System Diseases; Research; Reserpine; Syndrome

1956
[Akinetic-abulic syndrome and its importance in pharmacological-psychiatric research].
    Deutsche medizinische Wochenschrift (1946), 1956, Dec-21, Volume: 81, Issue:51

    Topics: Chlorpromazine; Humans; Mental Disorders; Nervous System Diseases; Research; Reserpine; Syndrome

1956
[Akinetic-abulic syndrome and its importance in pharmacological-psychiatric research].
    Deutsche medizinische Wochenschrift (1946), 1956, Dec-21, Volume: 81, Issue:51

    Topics: Chlorpromazine; Humans; Mental Disorders; Nervous System Diseases; Research; Reserpine; Syndrome

1956
[Akinetic-abulic syndrome and its importance in pharmacological-psychiatric research].
    Deutsche medizinische Wochenschrift (1946), 1956, Dec-21, Volume: 81, Issue:51

    Topics: Chlorpromazine; Humans; Mental Disorders; Nervous System Diseases; Research; Reserpine; Syndrome

1956
Zoxazolamine and/or chlorpromazine for muscle spasm.
    Journal of the American Medical Association, 1957, Sep-07, Volume: 165, Issue:1

    Topics: Chlorpromazine; Disease; Muscle Relaxants, Central; Muscles; Muscular Diseases; Nervous System Disea

1957
[Use of aminazine in the treatment of psychic and nervous diseases and also in other fields of medicine; review of Soviet and foreign literature for the year of 1956].
    Klinicheskaia meditsina, 1957, Volume: 35, Issue:9

    Topics: Chlorpromazine; Humans; Nervous System Diseases

1957
[Neurologic side-effects in megaphen therapy].
    Arztliche Wochenschrift, 1957, Aug-23, Volume: 12, Issue:34

    Topics: Biological Phenomena; Chlorpromazine; Humans; Nervous System Diseases; Physiological Phenomena

1957
[Nervous system complications of prolonged treatment with chlorpromazine].
    Journal de medecine de Bordeaux et du Sud-Ouest, 1958, Volume: 135, Issue:2

    Topics: Chlorpromazine; Humans; Nervous System Diseases

1958
Effect of chlorpromazine on muscle spasm in human tetanus.
    Lancet (London, England), 1958, May-10, Volume: 1, Issue:7028

    Topics: Chlorpromazine; Disease; Muscles; Muscular Diseases; Nervous System Diseases; Spasm; Tetanus; Tetanu

1958
Effects of chlorpromazine and promazine on perseveration.
    The Journal of general psychology, 1961, Volume: 65

    Topics: Behavior; Chlorpromazine; Humans; Mental Disorders; Nervous System Diseases; Promazine

1961
CEREBELLAR ATAXIA AS A NEUROLOGIC COMPLICATION OF VARICELLA IN A CHILD. CHLORPROMAZINE AS A THERAPEUTIC AGENT.
    The Medical annals of the District of Columbia, 1963, Volume: 32

    Topics: Ataxia; Cerebellar Ataxia; Chickenpox; Child; Chlorpromazine; Herpesvirus 3, Human; Humans; Nervous

1963
[NERVOUS DISEASES AND DRUG THERAPY].
    [Chiryo] [Therapy], 1964, Volume: 46

    Topics: Chlordiazepoxide; Chlorpromazine; Meprobamate; Nervous System Diseases; Neurologic Manifestations; P

1964
AN EXPERIMENTAL STUDY OF THE NEUROPATHOLOGICAL AND TOXICOLOGICAL EFFECTS OF CHLORPROMAZINE AND RESERPINE.
    Journal of neuropsychiatry, 1964, Volume: 5

    Topics: Cerebellum; Cerebrovascular Circulation; Chlorpromazine; Guinea Pigs; Nervous System Diseases; Parki

1964
[New concepts in the concept of nervous functioning and the effect of chlorpromazine].
    Die Medizinische, 1955, Feb-12, Volume: 7

    Topics: Chlorpromazine; Humans; Nervous System Diseases

1955
[Aminasine; review of the literature in psychiatric practice of one of phenothiazine derivatives].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1955, Volume: 55, Issue:4

    Topics: Chlorpromazine; Mental Disorders; Nervous System Diseases; Phenothiazines; Psychotherapy

1955
Adverse reactions to chlorpromazine in psychiatric patients.
    Diseases of the nervous system, 1974, Volume: 35, Issue:11

    Topics: Administration, Oral; Adult; Antipsychotic Agents; Autonomic Nervous System Diseases; Cardiovascular

1974
[Sensory disorders arising during neuroleptic therapy].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1980, Volume: 80, Issue:6

    Topics: Adolescent; Adult; Antipsychotic Agents; Basal Ganglia Diseases; Chlorpromazine; Female; Haloperidol

1980
Intrauterine effect of phenothiazines.
    The Medical journal of Australia, 1981, Apr-18, Volume: 1, Issue:8

    Topics: Adult; Chlorpromazine; Dystonia; Female; Fluphenazine; Humans; Infant; Infant, Newborn; Infant, Newb

1981
James Reilly and the autonomic nervous system. A prophet unheeded?
    Annals of the Royal College of Surgeons of England, 1978, Volume: 60, Issue:2

    Topics: Animals; Autonomic Nervous System; Capillary Permeability; Chlorpromazine; Gastrointestinal Hemorrha

1978
The impact on neurology of 40 years' advances in pharmacology.
    Brain : a journal of neurology, 1979, Volume: 102, Issue:3

    Topics: Acetylcholine; Chemical Phenomena; Chemistry; Chlorpromazine; Depression; Endorphins; Enkephalins; H

1979
A case of lithium-chlorpromazine interaction.
    The Journal of clinical psychiatry, 1986, Volume: 47, Issue:2

    Topics: Basal Ganglia Diseases; Chlorpromazine; Confusion; Drug Interactions; Drug Therapy, Combination; Hum

1986
Gas chromatographic-mass spectrometric determination of myo-inositol in human cerebrospinal fluid.
    Journal of neurochemistry, 1985, Volume: 45, Issue:2

    Topics: Adult; Arthritis, Rheumatoid; Chlorpromazine; Female; Gas Chromatography-Mass Spectrometry; Humans;

1985
The effect of dehydrobenzperidol, chlorpromazine and reserpine on the pituitary-adrenal system in human.
    Endokrinologie, 1971, Volume: 58, Issue:3

    Topics: Adrenocorticotropic Hormone; Arthritis, Rheumatoid; Benperidol; Chlorpromazine; Dexamethasone; Human

1971
[Treatment of the porphyrias].
    Bibliotheca psychiatrica et neurologica, 1969, Volume: 139

    Topics: Adenine Nucleotides; Barbiturates; Catalase; Cathartics; Chlorpromazine; Cholagogues and Choleretics

1969
[Neuroleptics, thymoleptics and tranquilizers in neurological therapy].
    Bibliotheca psychiatrica et neurologica, 1969, Volume: 139

    Topics: Basal Ganglia Diseases; Chlordiazepoxide; Chlorpromazine; Diazepam; Epilepsy; Extrapyramidal Tracts;

1969
[On the results of treatment and complications during the use of haloperidol in patients with long-term schizophrenia].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1969, Volume: 69, Issue:5

    Topics: Adult; Blood Pressure; Cardiovascular Diseases; Catatonia; Chlorpromazine; Cognition Disorders; Hall

1969
[Clinical studies on the circulatory dynamics of autonomic dysfunction in children. 3. Changes in the results of the Mark orthostatic test by loading and therapy with several drugs].
    Nihon Shonika Gakkai zasshi. Acta paediatrica Japonica, 1967, May-01, Volume: 71, Issue:5

    Topics: Adolescent; Atropine; Autonomic Nervous System; Child; Child, Preschool; Chlorpromazine; Epinephrine

1967