chlorpromazine has been researched along with Neoplasms in 74 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The single-institution, prospective, randomized trial was performed to evaluate the efficacy of tropisetron and chlorpromazine in the management of nausea and vomiting of terminal cancer patients." | 9.08 | Comparison of tropisetron and chlorpromazine combinations in the control of nausea and vomiting of patients with advanced cancer. ( Befon, S; Liossi, C; Mystakidou, K; Vlachos, L, 1998) |
| "These data suggest that 5-HT3 receptor antagonists such as tropisetron clinically are more effective in the control of emesis of patients with far advanced cancer than previously used agents." | 9.08 | Comparison of the efficacy and safety of tropisetron, metoclopramide, and chlorpromazine in the treatment of emesis associated with far advanced cancer. ( Befon, S; Liossi, C; Mystakidou, K; Vlachos, L, 1998) |
| "To investigate factors affecting the effectiveness and safety of intravenous chlorpromazine for irreversible delirium in patients with terminal cancer." | 7.88 | Factors Associated with the Effectiveness of Intravenous Administration of Chlorpromazine for Delirium in Patients with Terminal Cancer. ( Fujii, R; Fukunaga, M; Hasuo, H; Kanbara, K; Sakuma, H; Uchitani, K, 2018) |
| "The single-institution, prospective, randomized trial was performed to evaluate the efficacy of tropisetron and chlorpromazine in the management of nausea and vomiting of terminal cancer patients." | 5.08 | Comparison of tropisetron and chlorpromazine combinations in the control of nausea and vomiting of patients with advanced cancer. ( Befon, S; Liossi, C; Mystakidou, K; Vlachos, L, 1998) |
| "These data suggest that 5-HT3 receptor antagonists such as tropisetron clinically are more effective in the control of emesis of patients with far advanced cancer than previously used agents." | 5.08 | Comparison of the efficacy and safety of tropisetron, metoclopramide, and chlorpromazine in the treatment of emesis associated with far advanced cancer. ( Befon, S; Liossi, C; Mystakidou, K; Vlachos, L, 1998) |
| " In addition, characterization of the UGT1A locus and genetic studies directed at understanding the role of bilirubin glucuronidation and the biochemical basis of the clinical symptoms found in unconjugated hyperbilirubinemia have uncovered the structural gene polymorphisms associated with Crigler-Najjar's and Gilbert's syndrome." | 4.80 | Human UDP-glucuronosyltransferases: metabolism, expression, and disease. ( Strassburg, CP; Tukey, RH, 2000) |
| "To investigate factors affecting the effectiveness and safety of intravenous chlorpromazine for irreversible delirium in patients with terminal cancer." | 3.88 | Factors Associated with the Effectiveness of Intravenous Administration of Chlorpromazine for Delirium in Patients with Terminal Cancer. ( Fujii, R; Fukunaga, M; Hasuo, H; Kanbara, K; Sakuma, H; Uchitani, K, 2018) |
| "The antiemetic effect of domperidone against nausea, vomiting, and anorexia induced by antineoplastic agents was compared with that of chlorpromazine." | 3.66 | [Prophylactic antiemetic treatment for cancer chemotherapy--comparison of domperidone and chlorpromazine]. ( Araki, Y; Seita, M; Tamura, K, 1983) |
| "Chlorpromazine is an antipsychotic phenothiazine, safe at high doses and by many routes." | 2.67 | The use of chlorpromazine for symptom control in dying cancer patients. ( McIver, B; Nelson, K; Walsh, D, 1994) |
| "Sixty-nine patients with malignant tumors receiving cancer chemotherapy, 90% including cis-platinum, were evaluated in a randomized crossover study for the antiemetic efficacy and the side effects of two antiemetic regimens: chlorpromazine (CPM) 2." | 2.66 | Chlorpromazine and dexamethasone versus high-dose metoclopramide and dexamethasone in patients receiving cancer chemotherapy, particularly cis-platinum: a prospective randomized crossover study. ( Ben-Yosef, R; Biran, S; Brufman, G; Catane, R; Gez, E, 1989) |
| "Chlorpromazine was administered at a dose of 12." | 2.65 | [Randomized comparative trial of a new anti-emetic: nabilone, in cancer patients treated with cisplatin]. ( George, M; Kramar, A; Pejovic, MH; Thuaire, M; Wolff, JP, 1983) |
| "Thirty-seven adults with advanced cancer who were treated with cisplatin were randomly assigned to receive either synthetic long-acting ACTH (1 mg IM given 24 hours, 12 hours, and immediately preceding the administration of cisplatin) or a placebo given under the same conditions." | 2.65 | Adrenocorticotropic hormone in the prevention of cisplatin-induced nausea and vomiting. ( Colbert, N; Izrael, V; Laugier, A; Lotz, JP; Pene, F; Schlienger, M; Stoppa-Lyonnet, D; Vannetzel, JM, 1983) |
| "Subgroup analysis according to type of cancer was not possible due to insufficient data." | 2.55 | Corticosteroids for adult patients with advanced cancer who have nausea and vomiting (not related to chemotherapy, radiotherapy, or surgery). ( Good, P; Hardy, JR; Haywood, A; Khan, S; Rickett, K; Vayne-Bossert, P, 2017) |
| " There is no information on either long term dosing with these drugs or their use in patients with cancer related breathlessness." | 2.39 | The therapeutics of dyspnoea. ( Davis, CL, 1994) |
| "A vitamin B12 deficiency is unusual in pregnant women who consume a normal, varied diet." | 2.37 | Clinical chemistry of vitamin B12. ( Davis, RE, 1985) |
| "Hiccups occur in 15-40% of cancer patients, but previous research has not sought the perspectives of cancer healthcare providers." | 1.91 | Healthcare Providers' Experiences with Hiccups in Patients with Cancer: Report of a United States National Survey. ( Jatoi, A; Martin, N; Wieland, J, 2023) |
| " Patients were classified into single administration group (received a single dosage within 24 h before the assessment) and multiple administration group (received more than one dosage)." | 1.91 | Influence of dosing pattern of antipsychotics on treatment outcome of delirium in patients with advanced cancer. ( Abe, A; Fujisawa, D; Imai, K; Iwase, S; Maeda, I; Matsuda, Y; Matsuo, N; Mimura, M; Miyajima, K; Ogawa, A; Takeuchi, E; Takeuchi, M; Uemura, K; Watanabe, H; Yoshiuchi, K, 2023) |
| "However, many patients with incurable cancer have difficulty receiving oral administrations, which limits treatment options during disease progression." | 1.62 | The efficacy and safety of intravenous chlorpromazine treatment for sleep disturbance in patients with incurable cancer, with oral administration difficulty: a 1-week, prospective observational study. ( Fujii, R; Hasuo, H; Okada, M; Sakuma, H; Uchitani, K, 2021) |
| "HSP27 is overexpressed in many cancer types and influences cellular processes such as apoptosis, DNA repair, recombination, and formation of metastases." | 1.43 | New HSP27 inhibitors efficiently suppress drug resistance development in cancer cells. ( Donakonda, S; Haupt, VJ; Heinrich, JC; Lennig, P; Schroeder, M; Zhang, Y, 2016) |
| "With regard to cancer treatment, replication competent oncolytic adenoviruses have been safe in humans, although their efficacy has been variable." | 1.36 | Human adenovirus replication in immunocompetent Syrian hamsters can be attenuated with chlorpromazine or cidofovir. ( Bauerschmitz, GJ; Cerullo, V; Diaconu, I; Escutenaire, S; Hemminki, A; Hernandez-Alcoceba, R; Kanerva, A; Pesonen, S, 2010) |
| "Midazolam was used in 18 PS cases (10%)." | 1.35 | Use of palliative sedation for intractable symptoms in the palliative care unit of a comprehensive cancer center. ( Boohene, J; Bruera, E; Calderon, B; Curry Iii, E; Elsayem, A; Hung, F; Munsell, MF, 2009) |
| "Selective destruction of cancerous tissue can be achieved by modulating energy metabolism in malignant cells." | 1.29 | Successful cancer therapy with promethazine: the rationale. ( Jones, GR, 1996) |
| "Also, antiemesis was demonstrated in 66% of patients receiving such highly emetogenic chemotherapy." | 1.27 | Prolonged chlorpromazine infusion as antiemetic in patients on daily cisplatin infusion. A pilot study. ( Habbal, Z; Saab, GA; Shamseddine, A, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 46 (62.16) | 18.7374 |
| 1990's | 8 (10.81) | 18.2507 |
| 2000's | 3 (4.05) | 29.6817 |
| 2010's | 12 (16.22) | 24.3611 |
| 2020's | 5 (6.76) | 2.80 |
| Authors | Studies |
|---|---|
| Tukey, RH | 1 |
| Strassburg, CP | 1 |
| Choi, E | 1 |
| Lee, C | 1 |
| Park, JE | 1 |
| Seo, JJ | 1 |
| Cho, M | 1 |
| Kang, JS | 1 |
| Kim, HM | 1 |
| Park, SK | 1 |
| Lee, K | 1 |
| Han, G | 1 |
| Kastrinsky, DB | 1 |
| Sangodkar, J | 1 |
| Zaware, N | 1 |
| Izadmehr, S | 1 |
| Dhawan, NS | 1 |
| Narla, G | 1 |
| Ohlmeyer, M | 1 |
| Lin, R | 1 |
| Elf, S | 1 |
| Shan, C | 1 |
| Kang, HB | 1 |
| Ji, Q | 1 |
| Zhou, L | 1 |
| Hitosugi, T | 1 |
| Zhang, L | 1 |
| Zhang, S | 1 |
| Seo, JH | 1 |
| Xie, J | 1 |
| Tucker, M | 1 |
| Gu, TL | 1 |
| Sudderth, J | 1 |
| Jiang, L | 1 |
| Mitsche, M | 1 |
| DeBerardinis, RJ | 1 |
| Wu, S | 1 |
| Li, Y | 2 |
| Mao, H | 1 |
| Chen, PR | 1 |
| Wang, D | 1 |
| Chen, GZ | 1 |
| Hurwitz, SJ | 1 |
| Lonial, S | 1 |
| Arellano, ML | 1 |
| Khoury, HJ | 1 |
| Khuri, FR | 1 |
| Lee, BH | 1 |
| Lei, Q | 1 |
| Brat, DJ | 1 |
| Ye, K | 1 |
| Boggon, TJ | 1 |
| He, C | 1 |
| Kang, S | 1 |
| Fan, J | 1 |
| Chen, J | 1 |
| Pluta, K | 1 |
| Jeleń, M | 1 |
| Morak-Młodawska, B | 1 |
| Zimecki, M | 1 |
| Artym, J | 1 |
| Kocięba, M | 1 |
| Zaczyńska, E | 1 |
| Peterková, L | 1 |
| Kmoníčková, E | 1 |
| Ruml, T | 1 |
| Rimpelová, S | 1 |
| Brown, JS | 1 |
| Wieland, J | 1 |
| Martin, N | 1 |
| Jatoi, A | 1 |
| Abe, A | 1 |
| Fujisawa, D | 1 |
| Miyajima, K | 1 |
| Takeuchi, E | 1 |
| Takeuchi, M | 1 |
| Mimura, M | 1 |
| Imai, K | 1 |
| Uemura, K | 1 |
| Watanabe, H | 1 |
| Matsuo, N | 1 |
| Matsuda, Y | 1 |
| Maeda, I | 1 |
| Ogawa, A | 1 |
| Yoshiuchi, K | 1 |
| Iwase, S | 1 |
| Fujii, R | 2 |
| Hasuo, H | 2 |
| Sakuma, H | 2 |
| Okada, M | 1 |
| Uchitani, K | 2 |
| Vayne-Bossert, P | 1 |
| Haywood, A | 1 |
| Good, P | 1 |
| Khan, S | 1 |
| Rickett, K | 1 |
| Hardy, JR | 1 |
| Kanbara, K | 1 |
| Fukunaga, M | 1 |
| Qi, L | 1 |
| Ding, Y | 1 |
| Dong, S | 1 |
| Cho, HJ | 1 |
| Lee, YW | 1 |
| Roman, M | 1 |
| Smith, LA | 1 |
| Azariah, F | 1 |
| Lavender, VT | 1 |
| Stoner, NS | 1 |
| Bettiol, S | 1 |
| McGreal, S | 1 |
| Zhao, J | 1 |
| Huang, R | 1 |
| Zhou, Y | 1 |
| Zhong, H | 1 |
| Xia, M | 1 |
| Ding, WX | 1 |
| Heinrich, JC | 1 |
| Donakonda, S | 1 |
| Haupt, VJ | 1 |
| Lennig, P | 1 |
| Zhang, Y | 1 |
| Schroeder, M | 1 |
| Cuervo Pinna, MA | 1 |
| Mota Vargas, R | 1 |
| Redondo Moralo, MJ | 1 |
| Correas, MA | 1 |
| Diaconu, I | 1 |
| Cerullo, V | 1 |
| Escutenaire, S | 1 |
| Kanerva, A | 1 |
| Bauerschmitz, GJ | 1 |
| Hernandez-Alcoceba, R | 1 |
| Pesonen, S | 1 |
| Hemminki, A | 1 |
| SADOVE, MS | 1 |
| LEVIN, MJ | 1 |
| ROSE, RF | 1 |
| SCHWARTZ, L | 1 |
| WITT, FW | 1 |
| HOMBURGER, F | 1 |
| SMITHY, G | 1 |
| MEIER, I | 1 |
| LOFSTROM, B | 1 |
| PETERS, K | 1 |
| GARTNER, H | 1 |
| KRAIS, W | 1 |
| BENZER, A | 1 |
| CAITHAML, W | 1 |
| GROSZSCHEDL, A | 1 |
| STOLZER, H | 1 |
| CERRA, R | 1 |
| PERCESEPE, E | 1 |
| BACIGALUPO, G | 3 |
| ZENEVICH, GV | 1 |
| AMATRUDA, TT | 1 |
| MULROW, PJ | 1 |
| GALLAGHER, JC | 1 |
| SAWYER, WH | 1 |
| OLSZEWSKI, A | 1 |
| HOWARD, JM | 1 |
| STRAWITZ, JG | 1 |
| TANKEVICH, VM | 1 |
| SCHELL, HW | 1 |
| SMITH, EB | 1 |
| SJOERDSMA, A | 1 |
| MELMON, KL | 1 |
| POTTS, AM | 1 |
| MODELL, J | 1 |
| SCHWARTZ, S | 1 |
| CARLINI, GR | 1 |
| FISCHER, GA | 1 |
| GIARMAN, NJ | 1 |
| DAY, M | 1 |
| STOCKBRIDGE, A | 1 |
| LACASSAGNE, A | 1 |
| FINK, S | 1 |
| WINSLOW, WA | 1 |
| FABRIS, F | 1 |
| LUEHRS, W | 1 |
| KADENBACH, B | 1 |
| HEISE, E | 1 |
| SAVINSKAIA, AP | 1 |
| VIALARD, C | 1 |
| Elsayem, A | 1 |
| Curry Iii, E | 1 |
| Boohene, J | 1 |
| Munsell, MF | 1 |
| Calderon, B | 1 |
| Hung, F | 1 |
| Bruera, E | 1 |
| Teschke, R | 1 |
| George, M | 1 |
| Pejovic, MH | 1 |
| Thuaire, M | 1 |
| Kramar, A | 1 |
| Wolff, JP | 1 |
| Colbert, N | 1 |
| Izrael, V | 1 |
| Lotz, JP | 1 |
| Stoppa-Lyonnet, D | 1 |
| Vannetzel, JM | 1 |
| Pene, F | 1 |
| Schlienger, M | 1 |
| Laugier, A | 1 |
| Epstein, LH | 1 |
| Araki, Y | 1 |
| Tamura, K | 1 |
| Seita, M | 1 |
| McIver, B | 1 |
| Walsh, D | 1 |
| Nelson, K | 1 |
| Palmer, R | 1 |
| Davis, CL | 1 |
| Jones, GR | 2 |
| Mystakidou, K | 2 |
| Befon, S | 2 |
| Liossi, C | 2 |
| Vlachos, L | 2 |
| Ding, DC | 1 |
| Ventafridda, V | 1 |
| Spoldi, E | 1 |
| De Conno, F | 1 |
| Vanier, T | 1 |
| Gez, E | 1 |
| Ben-Yosef, R | 1 |
| Catane, R | 1 |
| Brufman, G | 1 |
| Biran, S | 1 |
| Shiu, W | 1 |
| Tsang, V | 1 |
| Lam, YM | 1 |
| Zacharia, A | 1 |
| Martin, WM | 1 |
| Saab, GA | 1 |
| Shamseddine, A | 1 |
| Habbal, Z | 1 |
| Akiyama, S | 1 |
| Shiraishi, N | 1 |
| Kuratomi, Y | 1 |
| Nakagawa, M | 1 |
| Kuwano, M | 1 |
| Shinkai, T | 1 |
| Saijo, N | 1 |
| Sawamura, N | 1 |
| Funaki, U | 1 |
| Takahashi, S | 1 |
| Yokoyama, S | 1 |
| Fujita, J | 1 |
| Futami, H | 1 |
| Sasaki, Y | 1 |
| Shimizu, E | 1 |
| Davis, RE | 1 |
| Csatary, LK | 1 |
| Kast, E | 1 |
| Vándor, F | 1 |
| Németh, G | 1 |
| Ravasz, L | 1 |
| Cutler, SJ | 1 |
| Greenhouse, SW | 1 |
| Cornfield, J | 1 |
| Schneiderman, MA | 1 |
| Kocher, R | 1 |
| Rohrer, G | 1 |
| Mullan, S | 1 |
13 reviews available for chlorpromazine and Neoplasms
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; | 2000 |
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; | 2015 |
Azaphenothiazines - promising phenothiazine derivatives. An insight into nomenclature, synthesis, structure elucidation and biological properties.
Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents; Antiprotozoal Agents; Anti | 2017 |
Sarco/Endoplasmic Reticulum Calcium ATPase Inhibitors: Beyond Anticancer Perspective.
Topics: Animals; Antineoplastic Agents; Enzyme Inhibitors; Gene Regulatory Networks; Humans; Neoplasms; Prot | 2020 |
Treatment of cancer with antipsychotic medications: Pushing the boundaries of schizophrenia and cancer.
Topics: Antipsychotic Agents; Chlorpromazine; Humans; Methylene Blue; Neoplasms; Phenothiazines; Reserpine; | 2022 |
Corticosteroids for adult patients with advanced cancer who have nausea and vomiting (not related to chemotherapy, radiotherapy, or surgery).
Topics: Adrenal Cortex Hormones; Adult; Chlorpromazine; Dexamethasone; Humans; Indoles; Metoclopramide; Naus | 2017 |
Cannabinoids for nausea and vomiting in adults with cancer receiving chemotherapy.
Topics: Adult; Antiemetics; Antineoplastic Agents; Cannabinoids; Chlorpromazine; Dizziness; Domperidone; Eup | 2015 |
The direct effects of compliance on health outcome.
Topics: Alcoholism; Chlorpromazine; Chorionic Gonadotropin; Clofibrate; Coronary Disease; Disulfiram; Drug T | 1984 |
Efficacy and safety of granisetron (Kytril) in two special patient populations: children and adults with impaired hepatic function.
Topics: Adult; Antineoplastic Agents; Child; Child, Preschool; Chlorpromazine; Clinical Trials as Topic; Dex | 1994 |
The therapeutics of dyspnoea.
Topics: Analgesics, Opioid; Anesthetics, Local; Anti-Anxiety Agents; Anti-Inflammatory Agents, Non-Steroidal | 1994 |
[The control of chemotherapy-induced nausea and vomiting].
Topics: Antiemetics; Antineoplastic Agents; Chemoreceptor Cells; Chlorpromazine; Cisplatin; Domperidone; Hum | 1985 |
Cancer therapy: phenothiazines in an unexpected role.
Topics: Animals; Chlorpromazine; Hospitals, Psychiatric; Humans; Neoplasms; Neoplasms, Experimental; Oxidati | 1985 |
Clinical chemistry of vitamin B12.
Topics: Absorption; Adult; Alcoholism; Anemia, Pernicious; Ascorbic Acid; Autoantibodies; Biguanides; Biolog | 1985 |
11 trials available for chlorpromazine and Neoplasms
| Article | Year |
|---|---|
[Randomized comparative trial of a new anti-emetic: nabilone, in cancer patients treated with cisplatin].
Topics: Adolescent; Adult; Aged; Antiemetics; Chlorpromazine; Cisplatin; Clinical Trials as Topic; Double-Bl | 1983 |
Adrenocorticotropic hormone in the prevention of cisplatin-induced nausea and vomiting.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Antiemetics; Chlorpromazine; Cisplatin; Clinical Trials as | 1983 |
The direct effects of compliance on health outcome.
Topics: Alcoholism; Chlorpromazine; Chorionic Gonadotropin; Clofibrate; Coronary Disease; Disulfiram; Drug T | 1984 |
The use of chlorpromazine for symptom control in dying cancer patients.
Topics: Chlorpromazine; Humans; Neoplasms; Terminal Care | 1994 |
Comparison of tropisetron and chlorpromazine combinations in the control of nausea and vomiting of patients with advanced cancer.
Topics: Adult; Aged; Antiemetics; Chlorpromazine; Drug Therapy, Combination; Female; Humans; Indoles; Male; | 1998 |
Comparison of the efficacy and safety of tropisetron, metoclopramide, and chlorpromazine in the treatment of emesis associated with far advanced cancer.
Topics: Adult; Aged; Antiemetics; Chlorpromazine; Dexamethasone; Drug Therapy, Combination; Female; Humans; | 1998 |
The Brompton cocktail.
Topics: Chemistry, Pharmaceutical; Chlorpromazine; Clinical Trials as Topic; Cocaine; Drug Combinations; Dru | 1979 |
Chlorpromazine and dexamethasone versus high-dose metoclopramide and dexamethasone in patients receiving cancer chemotherapy, particularly cis-platinum: a prospective randomized crossover study.
Topics: Adolescent; Adult; Aged; Antiemetics; Chlorpromazine; Cisplatin; Clinical Trials as Topic; Dexametha | 1989 |
A randomised cross-over trial comparing low-dose metoclopramide and chlorpromazine with high-dose metoclopramide in Chinese patients with advanced cancer receiving cisplatinum and 5-fluorouracil.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorpromazine; Cisplatin; Clinical Tri | 1987 |
The role of hypothesis testing in clinical trials. Biometrics seminar.
Topics: Biometry; Cardiovascular Diseases; Chlorpromazine; Clinical Trials as Topic; Coronary Disease; Estro | 1966 |
[Treatment of severe chronic pains with a combination of thymoleptics and neuroleptics (author's transl)].
Topics: Adult; Antidepressive Agents; Atropine; Chlorpromazine; Clinical Trials as Topic; Clomipramine; Drug | 1974 |
51 other studies available for chlorpromazine and Neoplasms
| Article | Year |
|---|---|
Structure and property based design, synthesis and biological evaluation of γ-lactam based HDAC inhibitors.
Topics: Animals; Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Cell Membrane Permeability; Compute | 2011 |
Reengineered tricyclic anti-cancer agents.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Dibenzazepines; Heterocyclic Compou | 2015 |
Healthcare Providers' Experiences with Hiccups in Patients with Cancer: Report of a United States National Survey.
Topics: Baclofen; Chlorpromazine; Hiccup; Humans; Neoplasms; United States | 2023 |
Influence of dosing pattern of antipsychotics on treatment outcome of delirium in patients with advanced cancer.
Topics: Antipsychotic Agents; Chlorpromazine; Delirium; Female; Humans; Male; Neoplasms; Treatment Outcome | 2023 |
The efficacy and safety of intravenous chlorpromazine treatment for sleep disturbance in patients with incurable cancer, with oral administration difficulty: a 1-week, prospective observational study.
Topics: Administration, Oral; Chlorpromazine; Humans; Neoplasms; Sleep; Sleep Wake Disorders | 2021 |
Factors Associated with the Effectiveness of Intravenous Administration of Chlorpromazine for Delirium in Patients with Terminal Cancer.
Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Chlorpromazine; D | 2018 |
Potential antitumor mechanisms of phenothiazine drugs.
Topics: Antineoplastic Agents; Cell Proliferation; Chlorpromazine; Computational Biology; Drug Delivery Syst | 2013 |
Synthesis and cellular uptake of folic acid-conjugated cellulose nanocrystals for cancer targeting.
Topics: Animals; Caveolae; Cellulose; Chlorpromazine; Clathrin; Drug Carriers; Endocytosis; Folate Receptors | 2014 |
A cell-based quantitative high-throughput image screening identified novel autophagy modulators.
Topics: A549 Cells; Animals; Antineoplastic Agents; Autophagy; Biological Assay; Chlorpromazine; Dopamine An | 2016 |
New HSP27 inhibitors efficiently suppress drug resistance development in cancer cells.
Topics: Antipsychotic Agents; Apoptosis; Cell Line, Tumor; Chlorpromazine; Computational Biology; Cytostatic | 2016 |
Pharmacologic intervention for cancer-related dyspnea.
Topics: Analgesics, Opioid; Chlorpromazine; Dyspnea; Fentanyl; Humans; Neoplasms; Palliative Care; Randomize | 2008 |
Human adenovirus replication in immunocompetent Syrian hamsters can be attenuated with chlorpromazine or cidofovir.
Topics: Adenoviridae Infections; Adenoviruses, Human; Animals; Biological Transport; Cell Death; Cell Line; | 2010 |
Chlorpromazine and narcotics in the management of pain of malignant lesions.
Topics: Autonomic Agents; Chlorpromazine; Disease Management; Narcotics; Neoplasms; Pain Management | 1954 |
Chlorpromazine in patients with nausea and vomiting due to advanced cancer.
Topics: Chlorpromazine; Humans; Nausea; Neoplasms; Vomiting | 1954 |
[The analgetic significance and effects of chlorpromazine, with special reference to cancer].
Topics: Chlorpromazine; Humans; Neoplasms; Pain Management | 1954 |
[Chlorpromazine analgetics in therapy of pain in advanced cancer; case survey].
Topics: Chlorpromazine; Data Collection; Neoplasms; Pain | 1954 |
[Separate and combined effects of radium and megaphen on ascitic tumor in mice].
Topics: Animals; Chlorpromazine; Mice; Neoplasms; Neoplasms, Experimental; Radium | 1955 |
[Surgery of cancer of the esophagus, of the cardia and of the upper gastric portion with suppression of the autonomic nervous system].
Topics: Autonomic Nervous System; Cardia; Chlorpromazine; Esophageal Neoplasms; Humans; Neoplasms; Stomach N | 1955 |
[Clinical study of the use of a drug containing a combination of chlorpromazine, gardenal and theophylline-ethylenediamine in patients of malignant neoplasms].
Topics: Aminophylline; Biomedical Research; Chlorpromazine; Electroencephalography; Humans; Neoplasms; Pheno | 1958 |
[Clinical results of a new combined procedure for the treatment of malignant tumors in man].
Topics: Antineoplastic Agents; Chlorpromazine; Neoplasms; Triiodothyronine | 1960 |
[On remissions in patients with schizophrenia after treatment with neuroleptic substances and supportive therapy].
Topics: Antipsychotic Agents; Chlorpromazine; Neoplasms; Schizophrenia | 1961 |
CARCINOMA OF THE LUNG WITH INAPPROPRIATE ANTIDIURESIS. DEMONSTRATION OF ANTIDIURETIC-HORMONE-LIKE ACTIVITY IN TUMOR EXTRACT.
Topics: Autonomic Nerve Block; Carcinoma; Chlorpromazine; Geriatrics; Histocytochemistry; Humans; Kidney Dis | 1963 |
THE USE OF SEROTONIN, CHLORPROMAZINE AND OTHER AGENTS FOR CONDITIONING HOSTS FOR TUMOR HETEROTRANSPLANTATION.
Topics: Chlorpromazine; Cortisone; Neoplasms; Neoplasms, Experimental; Phenoxybenzamine; Radiation Effects; | 1963 |
[GASEOUS STATE OF THE BLOOD AND REMOTE HEMODYNAMIC INDICES IN PATIENTS SURGICALLY TREATED UNDER POTENTIATED ANESTHESIA AND INTUBATION ANESTHESIA].
Topics: Anesthesia; Anesthesia, Endotracheal; Blood Gas Analysis; Chlorpromazine; Hemodynamics; Hibernation; | 1963 |
CURRENT STATUS OF 5-FLUOROURACIL THERAPY IN FAR-ADVANCED NEOPLASTIC DISEASE.
Topics: Alopecia; Chlorpromazine; Diarrhea; Erythema; Fluorouracil; Leukopenia; Nausea; Neoplasms; Thrombocy | 1964 |
SURGICAL MANAGEMENT OF THE NEUROPSYCHIATRIC PATIENT.
Topics: Appendicitis; Chlorpromazine; Gastrectomy; Geriatrics; Humans; Mental Disorders; Mortality; Neoplasm | 1964 |
UNCOUPLING THE OXIDATIVE PHOSPHORYLATION IN THE COMBINED CHEMOTHERAPY OF CANCER.
Topics: Adenosine Triphosphate; Antimetabolites; Antineoplastic Agents; Carcinoma 256, Walker; Chlorpromazin | 1964 |
THE CARCINOID SPECTRUM.
Topics: 5-Hydroxytryptophan; Angiotensins; Antineoplastic Agents; Bronchial Neoplasms; Carcinoid Tumor; Chlo | 1964 |
TRACER STUDIES ON A TRANSPLANTABLE HAMSTER MELANOMA.
Topics: Animals; Chlorpromazine; Cricetinae; Eye Neoplasms; Fluoresceins; Idoxuridine; Iodine Isotopes; Mela | 1964 |
SOME ANTAGONISTIC EFFECTS OF "HEMATOPORPHYRIN" AND PROTOPORPHYRIN IN MICE.
Topics: Atropine; Chlorpheniramine; Chlorpromazine; Dinitrophenols; Edetic Acid; Hematoporphyrins; Heparin; | 1964 |
DIFFERENCES IN CHARACTERISTICS OF RELEASE OF SEROTONIN FROM NEOPLASTIC MAST CELLS IN CULTURE BY RESERPINE AND CHLORPROMAZINE.
Topics: Chlorpromazine; Mast Cells; Metabolism; Monoamine Oxidase Inhibitors; Neoplasms; Neoplasms, Experime | 1964 |
THE EFFECTS OF DRUGS ON THE UPTAKE OF AMINES BY MAST CELLS.
Topics: Amines; Animals; Chlorpromazine; Cocaine; Ethanolamines; Guanethidine; Hallucinogens; Histamine; Imi | 1964 |
[RELATIONS BETWEEN THE TUMOR AND ORGANISM. THE ROLE OF THE HYPOTHALAMUS].
Topics: Chlorpromazine; Gold; Hypothalamus; Neoplasms; Neoplasms, Experimental; Neurophysiology; Pharmacolog | 1964 |
Anti-emetic effect of chlorpromazine (thorazine) in cancer patients.
Topics: Antiemetics; Chlorpromazine; Humans; Nausea; Neoplasms; Radiotherapy; Uremia | 1955 |
[Treatment of pain in cancer].
Topics: Anti-Allergic Agents; Chlorpromazine; Histamine H1 Antagonists; Neoplasms; Pain Management | 1955 |
[The influence of chlorpromazine on oxidative phosphorylation in tumor mitochondria].
Topics: Chlorpromazine; Leadership; Liver; Mitochondria; Neoplasms; Oxidative Phosphorylation | 1959 |
[Effect of aminazin and iprazide on the appearance and development of induced tumors in rats].
Topics: Animals; Chlorpromazine; Iproniazid; Neoplasms; Neoplasms, Experimental; Rats | 1962 |
[Note on the utilization of largactil (4560 RP) as potentiator of analgesics in painful cancer resistant to opiates].
Topics: Analgesics; Analgesics, Opioid; Autonomic Agents; Chlorpromazine; Humans; Neoplasms; Pain | 1953 |
Use of palliative sedation for intractable symptoms in the palliative care unit of a comprehensive cancer center.
Topics: Adult; Aged; Aged, 80 and over; Cancer Care Facilities; Chlorpromazine; Female; Humans; Hypnotics an | 2009 |
[Alcoholic liver diseases. Biochemical and clinical studies on pathogenesis and early diagnosis].
Topics: Acetaldehyde; Alcohol Oxidoreductases; Biochemical Phenomena; Biochemistry; Catalase; Chlorpromazine | 1980 |
[Prophylactic antiemetic treatment for cancer chemotherapy--comparison of domperidone and chlorpromazine].
Topics: Adult; Aged; Antineoplastic Agents; Chlorpromazine; Domperidone; Female; Humans; Male; Middle Aged; | 1983 |
Successful cancer therapy with promethazine: the rationale.
Topics: Antineoplastic Agents; Breast Neoplasms; Chlorpromazine; Cyclophosphamide; Female; Humans; Male; Neo | 1996 |
[Clinical multivariate statistical analysis of nephrotoxicity induced by cisplatin].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; beta 2-Microglobulin; Chlorpromazine; Cisplat | 1992 |
Control of dyspnea in advanced cancer patients.
Topics: Chlorpromazine; Drug Therapy, Combination; Dyspnea; Humans; Morphine; Neoplasms; Palliative Care | 1990 |
[The control of pain].
Topics: Adult; Aged; Chlorpromazine; Female; Humans; Male; Middle Aged; Morphine; Neoplasms; Nerve Block; Pa | 1986 |
Prolonged chlorpromazine infusion as antiemetic in patients on daily cisplatin infusion. A pilot study.
Topics: Adult; Aged; Antiemetics; Chlorpromazine; Cisplatin; Female; Humans; Infusions, Intravenous; Male; M | 1988 |
Circumvention of multiple-drug resistance in human cancer cells by thioridazine, trifluoperazine, and chlorpromazine.
Topics: Calmodulin; Cell Line; Chlorpromazine; Daunorubicin; Drug Resistance; Humans; KB Cells; Lysosomes; N | 1986 |
Chlorpromazines and cancer.
Topics: Animals; Chlorpromazine; Cricetinae; Humans; Mental Disorders; Mice; Neoplasms; Oxidative Phosphoryl | 1972 |
LSD and the dying patient.
Topics: Chlorpromazine; Death; Humans; Lysergic Acid Diethylamide; Neoplasms; Palliative Care | 1966 |
[Hibernal in the treatment of tumor patients].
Topics: Animals; Chlorpromazine; Humans; Male; Middle Aged; Neoplasms; Palliative Care; Rats | 1967 |
Surgical management of pain in cancer of the head and neck.
Topics: Alcohols; Autonomic Nerve Block; Carbamazepine; Chlorpromazine; Cranial Nerves; Gastrostomy; Head; H | 1973 |