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chlorpromazine and Muscular Diseases

chlorpromazine has been researched along with Muscular Diseases in 23 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Muscular Diseases: Acquired, familial, and congenital disorders of SKELETAL MUSCLE and SMOOTH MUSCLE.

Research Excerpts

ExcerptRelevanceReference
"The incidence of muscle pains and changes in serum concentrations of potassium, calcium and creatine kinase following suxamethonium were investigated after no pretreatment or pretreatment with intravenous tubocurarine 0."5.07Muscle pains and biochemical changes following suxamethonium administration after six pretreatment regimens. ( Elliott, P; McCarthy, G; McLoughlin, C; Mirakhur, RK, 1992)
"After receiving 90 mg of haloperidol and 100 mg of chlorpromazine hydrochloride within 25 hours, a 29-year-old man was found to have neuroleptic malignant syndrome (NMS), characterized by the acute onset of hyperpyrexia, extreme muscular rigidity, autonomic instability, and coma."3.67Neuroleptic malignant syndrome and dopaminergic blockade. ( Hashimoto, F; Jeffery, WH; Sherman, CB, 1984)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199020 (86.96)18.7374
1990's3 (13.04)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
GUIRAL, RJ2
BLANC, M1
LOISEAU, P1
DES TERMES, M1
STAEFFEN, J1
GIBSON, JW1
BLUESTONE, SS1
LOWMAN, EW1
BARR, MN1
Keary, EM1
Maxwell, DR1
Brumback, RA2
Empting, L1
Susag, ME1
Staton, RD2
Svendsen, O1
Ichijo, M1
Ishihara, T1
Uchida, A1
Mori, K1
Hashimoto, F1
Sherman, CB1
Jeffery, WH1
Takagi, A1
Saito, K1
Kakei, M1
Uchimura, S1
Kashima, T1
Tanaka, H1
Faucher, L1
Marcoux, D1
Babu, AS1
Gowda, TV1
Mann, SC1
Boger, WP1
Drenckhahn, D1
Lüllmann-Rauch, R1
McLoughlin, C1
Elliott, P1
McCarthy, G1
Mirakhur, RK1
James, IP1
Voiculescu, V1
Călcăianu, G1
Stănescu, A1
Penn, AS1
Rowland, LP1
Fraser, DW1
Bree, MM1
Cohen, BJ1
Abrams, GD1
Patten, JP1
Cottom, DG1
Newman, CG1

Reviews

1 review available for chlorpromazine and Muscular Diseases

ArticleYear
[Physiology and biochemistry of muscle fibers and the effect of disease. Skinned fiber technic].
    No to shinkei = Brain and nerve, 1982, Volume: 34, Issue:10

    Topics: Biomechanical Phenomena; Chlorpromazine; Cytological Techniques; Humans; Malignant Hyperthermia; Mus

1982

Trials

1 trial available for chlorpromazine and Muscular Diseases

ArticleYear
Muscle pains and biochemical changes following suxamethonium administration after six pretreatment regimens.
    Anaesthesia, 1992, Volume: 47, Issue:3

    Topics: Adolescent; Adult; Aged; Aspirin; Calcium; Calcium Chloride; Chlorpromazine; Creatine Kinase; Female

1992

Other Studies

21 other studies available for chlorpromazine and Muscular Diseases

ArticleYear
[Use of chlorpromazine in the psychosomatic type of autonomic dystonias].
    L'Encephale, 1956, Volume: 45, Issue:4

    Topics: Autonomic Nervous System; Autonomic Nervous System Diseases; Chlorpromazine; Disease; Dystonia; Huma

1956
[Use of chlorpromazine in the psychosomatic type of autonomic dystonias].
    L'Encephale, 1956, Volume: 45, Issue:4

    Topics: Autonomic Nervous System; Autonomic Nervous System Diseases; Chlorpromazine; Disease; Dystonia; Huma

1956
[Use of chlorpromazine in the psychosomatic type of autonomic dystonias].
    L'Encephale, 1956, Volume: 45, Issue:4

    Topics: Autonomic Nervous System; Autonomic Nervous System Diseases; Chlorpromazine; Disease; Dystonia; Huma

1956
[Use of chlorpromazine in the psychosomatic type of autonomic dystonias].
    L'Encephale, 1956, Volume: 45, Issue:4

    Topics: Autonomic Nervous System; Autonomic Nervous System Diseases; Chlorpromazine; Disease; Dystonia; Huma

1956
[Myoclonias during chlorpromazine treatment; analysis].
    Journal de medecine de Bordeaux et du Sud-Ouest, 1957, Volume: 134, Issue:4

    Topics: Chlorpromazine; Humans; Movement Disorders; Muscular Diseases; Myoclonus

1957
Zoxazolamine and/or chlorpromazine for muscle spasm.
    Journal of the American Medical Association, 1957, Sep-07, Volume: 165, Issue:1

    Topics: Chlorpromazine; Disease; Muscle Relaxants, Central; Muscles; Muscular Diseases; Nervous System Disea

1957
Effect of chlorpromazine on muscle spasm in human tetanus.
    Lancet (London, England), 1958, May-10, Volume: 1, Issue:7028

    Topics: Chlorpromazine; Disease; Muscles; Muscular Diseases; Nervous System Diseases; Spasm; Tetanus; Tetanu

1958
A comparison of the effects of chlorpromazine and some related phenothiazines in reducing the rigidity of the decerebrate cat and in some other central actions.
    British journal of pharmacology and chemotherapy, 1967, Volume: 30, Issue:2

    Topics: Animals; Barbiturates; Blood Pressure; Cats; Chlordiazepoxide; Chlorpromazine; Decerebrate State; El

1967
Muscle fibrosis associated with intramuscular chlorpromazine administration. A preliminary report.
    The Journal of pharmacy and pharmacology, 1982, Volume: 34, Issue:8

    Topics: Animals; Chlorpromazine; Humans; Injections, Intramuscular; Male; Middle Aged; Muscular Diseases; Ne

1982
Local muscle damage and oily vehicles: a study on local reactions in rabbits after intramuscular injection of neuroleptic drugs in aqueous or oily vehicles.
    Acta pharmacologica et toxicologica, 1983, Volume: 52, Issue:4

    Topics: Animals; Antipsychotic Agents; Chlorpromazine; Clopenthixol; Female; Haloperidol; Injections, Intram

1983
[Case of syndrome malin with a transient appearance of "multicore"].
    Rinsho shinkeigaku = Clinical neurology, 1983, Volume: 23, Issue:9

    Topics: Adult; Chlorpromazine; Coxsackievirus Infections; Dehydration; Enterovirus B, Human; Humans; Hypergl

1983
Neuroleptic malignant syndrome and dopaminergic blockade.
    Archives of internal medicine, 1984, Volume: 144, Issue:3

    Topics: Adult; Chlorpromazine; Dopamine; Haloperidol; Humans; Male; Muscular Diseases; Receptors, Dopamine;

1984
Muscle granulomas after injection.
    Muscle & nerve, 1983, Volume: 6, Issue:5

    Topics: Animals; Chlorpromazine; Granuloma; Injections, Intramuscular; Muscular Diseases; Pentazocine; Rabbi

1983
Toxic effects of chlorpromazine on red and white muscles in rats: an ultrastructural study.
    Toxicology and applied pharmacology, 1982, Sep-30, Volume: 65, Issue:3

    Topics: Animals; Chlorpromazine; Male; Mitochondria, Muscle; Muscles; Muscular Diseases; Myelin Sheath; Rats

1982
What syndrome is this? Nicolau syndrome.
    Pediatric dermatology, 1995, Volume: 12, Issue:2

    Topics: Child, Preschool; Chlorpromazine; Drug Eruptions; Erythema; Humans; Injections, Intramuscular; Leg U

1995
Effects of chlorpromazine on the enzymatic and toxic properties of the most basic phospholipase A2 from Vipera russelli snake venom.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1995, Volume: 44, Issue:8

    Topics: Animals; Anticoagulants; Chlorpromazine; Edema; Hemolysis; L-Lactate Dehydrogenase; Lethal Dose 50;

1995
Psychotropic drugs, summer heat and humidity, and hyperpyrexia: a danger restated.
    The American journal of psychiatry, 1978, Volume: 135, Issue:9

    Topics: Antipsychotic Agents; Body Temperature Regulation; Chlorpromazine; Humans; Kidney Tubular Necrosis,

1978
Experimental myopathy induced by amphiphilic cationic compounds including several psychotropic drugs.
    Neuroscience, 1979, Volume: 4, Issue:4

    Topics: Amitriptyline; Animals; Chloroquine; Chlorphentermine; Chlorpromazine; Female; Imipramine; Iprindole

1979
Acute phenothiazine dystonia in narcotic addicts.
    Lancet (London, England), 1969, Nov-29, Volume: 2, Issue:7631

    Topics: Chlorpromazine; Humans; Muscular Diseases; Parasympatholytics; Substance Withdrawal Syndrome; Substa

1969
Abnormal reflexes in the "stiff-man" syndrome.
    Revue roumaine de neurologie, 1970, Volume: 7, Issue:3

    Topics: Adrenocorticotropic Hormone; Chloral Hydrate; Chlorpromazine; Cortisone; Electromyography; Female; F

1970
Drugs, coma, and myoglobinuria.
    Archives of neurology, 1972, Volume: 26, Issue:4

    Topics: Acute Kidney Injury; Adult; Aspartate Aminotransferases; Barbiturates; Chlorpromazine; Coma; Drug-Re

1972
Injection lesions following intramuscular administration of chlorpromazine in rabbits.
    Journal of the American Veterinary Medical Association, 1971, Dec-01, Volume: 159, Issue:11

    Topics: Animals; Chlorpromazine; Inflammation; Injections, Intramuscular; Male; Muscular Diseases; Necrosis;

1971
Chlorpromazine in dystonic reactions.
    British medical journal, 1968, Mar-09, Volume: 1, Issue:5592

    Topics: Adult; Chlorpromazine; Female; Humans; Muscular Diseases

1968
Dystonic reactions to phenothiazine derivatives.
    Archives of disease in childhood, 1966, Volume: 41, Issue:219

    Topics: Adolescent; Child; Child, Preschool; Chlorpromazine; Female; Fluphenazine; Humans; Male; Muscular Di

1966