chlorpromazine has been researched along with Muscle Spasticity in 14 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Muscle Spasticity: A form of muscle hypertonia associated with upper MOTOR NEURON DISEASE. Resistance to passive stretch of a spastic muscle results in minimal initial resistance (a free interval) followed by an incremental increase in muscle tone. Tone increases in proportion to the velocity of stretch. Spasticity is usually accompanied by HYPERREFLEXIA and variable degrees of MUSCLE WEAKNESS. (From Adams et al., Principles of Neurology, 6th ed, p54)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Reduction of motor tone in spastic muscles, as well as improvement in functiional status, was observed." | 1.26 | Phenytoin and chlorpromazine in the treatment of spasticity. ( Armitage, P; Cohan, SL; Panagakos, J; Raines, A, 1980) |
| "Symptoms of a spastic paresis only develop later when the spinal interneurones are destroyed as a consequence of the lesion of the neuroglia." | 1.26 | Spastic paresis after 6-aminonicotinamide: metabolic disorders in the spinal cord and electromyographically recorded changes in the hind limbs of rats. ( Halbhübner, K; Herken, H; Loos, D; Meyer-Estorf, G, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (92.86) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| D'Amico, JM | 1 |
| Murray, KC | 1 |
| Li, Y | 1 |
| Chan, KM | 1 |
| Finlay, MG | 1 |
| Bennett, DJ | 1 |
| Gorassini, MA | 1 |
| BASMAJIAN, JV | 2 |
| SZATMARI, A | 2 |
| HENATSCH, HD | 2 |
| INGVAR, DH | 2 |
| KRIZ, K | 2 |
| KUKUEV, LA | 1 |
| ABOVIAN, VA | 1 |
| SKORPIL, V | 1 |
| DRECHSLFR, B | 1 |
| JANDA, V | 1 |
| PFEIFFER, J | 1 |
| PEDERSEN, E | 2 |
| Cohan, SL | 1 |
| Raines, A | 1 |
| Panagakos, J | 1 |
| Armitage, P | 1 |
| Hopkin, DA | 1 |
| Herken, H | 1 |
| Meyer-Estorf, G | 1 |
| Halbhübner, K | 1 |
| Loos, D | 1 |
| Vakil, BJ | 1 |
| Singhal, BS | 1 |
| Pandya, SS | 1 |
| Irani, PF | 1 |
| Baykuschev, S | 1 |
1 review available for chlorpromazine and Muscle Spasticity
| Article | Year |
|---|---|
[MEDICAL TREATMENT OF SPASTICITY].
Topics: Barbiturates; Chlordiazepoxide; Chlormezanone; Chlorpromazine; Curare; Humans; Mephenesin; Meprobama | 1964 |
13 other studies available for chlorpromazine and Muscle Spasticity
| Article | Year |
|---|---|
Constitutively active 5-HT2/α1 receptors facilitate muscle spasms after human spinal cord injury.
Topics: Action Potentials; Adult; Aged; Biogenic Monoamines; Calcium; Case-Control Studies; Chlorpromazine; | 2013 |
Effect of largactil (chlorpromazine) on human spasticity and electromyogram; preliminary report.
Topics: Brain Diseases; Cerebral Cortex; Chlorpromazine; Disease; Electromyography; Muscle Spasticity; Spasm | 1955 |
Chlorpromazine and human spasticity; an electromyographic study.
Topics: Chlorpromazine; Electromyography; Humans; Muscle Spasticity; Spasm | 1955 |
[Chlorpromazine and spasticity; an experimental electrophysiological study].
Topics: Chlorpromazine; Muscle Spasticity | 1956 |
[Chlorpromazine and spasticity; an experimental electrophysiological study].
Topics: Chlorpromazine; Muscle Spasticity | 1956 |
[Chlorpromazine and spasticity; an experimental electrophysiological study].
Topics: Chlorpromazine; Muscle Spasticity | 1956 |
[Chlorpromazine and spasticity; an experimental electrophysiological study].
Topics: Chlorpromazine; Muscle Spasticity | 1956 |
[Chlorpromazine in rehabilitation in spastic paralysis].
Topics: Chlorpromazine; Humans; Medicine; Muscle Spasticity; Paralysis | 1956 |
[Chlorpromazine in rehabilitation in spastic paralysis].
Topics: Chlorpromazine; Humans; Medicine; Muscle Spasticity; Paralysis | 1956 |
[Chlorpromazine in rehabilitation in spastic paralysis].
Topics: Chlorpromazine; Humans; Medicine; Muscle Spasticity; Paralysis | 1956 |
[Chlorpromazine in rehabilitation in spastic paralysis].
Topics: Chlorpromazine; Humans; Medicine; Muscle Spasticity; Paralysis | 1956 |
[Use of aminazine in spastic paralysis following insultus].
Topics: Chlorpromazine; Humans; Muscle Spasticity; Paralysis | 1959 |
[Pharmacological influences in reflex neuromuscular irritability in spastic subjects].
Topics: Chlorpromazine; Humans; Leadership; Muscle Spasticity; Paralysis; Reflex | 1959 |
Phenytoin and chlorpromazine in the treatment of spasticity.
Topics: Adult; Aged; Chlorpromazine; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Motor Neu | 1980 |
Management of spasticity on neurophysiological basis.
Topics: Baclofen; Chlorpromazine; Cryosurgery; Curare; Dantrolene; Diazepam; Humans; Moxisylyte; Muscle Spas | 1980 |
Postoperative spasticity and shivering.
Topics: Chlorpromazine; Humans; Muscle Spasticity; Postoperative Complications; Shivering | 1984 |
Spastic paresis after 6-aminonicotinamide: metabolic disorders in the spinal cord and electromyographically recorded changes in the hind limbs of rats.
Topics: 6-Aminonicotinamide; Action Potentials; Animals; Baclofen; Brain; Chlorpromazine; Electromyography; | 1976 |
Cephalic tetanus.
Topics: Adult; Antitoxins; Barbiturates; Chlorpromazine; Electromyography; Facial Nerve; Facial Paralysis; F | 1973 |
[The effect of chlorpromazine on inhibitory processes in the spinal cord of patients with spastic paralyses].
Topics: Cerebrovascular Disorders; Chlorpromazine; Electromyography; Encephalitis; Humans; Motor Neurons; Mu | 1968 |