chlorpromazine has been researched along with Muscle Contraction in 120 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In both the CPZ-treated and nontreated groups, ischemia induced a decline in muscle glycogen content, with a corresponding increase in muscle lactate and a decrease in mitochondrial respiratory control ratio." | 5.32 | Lack of chlorpromazine effect on skeletal muscle metabolism after ischemia and a short reperfusion period. ( Cherri, J; Massuda, CA; Piccinato, CE; Salles Roselino, JE, 2004) |
| "5-100 microM chlorpromazine hydrochloride (CPZ) on the major steps of the excitation-contraction (E-C) coupling to elucidate the involvement of skeletal muscle in the neuroleptic malignant syndrome (NMS)." | 3.72 | Effects of chlorpromazine on excitation-contraction coupling events in fast-twitch skeletal muscle fibres of the rat. ( Fink, RH; Stephenson, DG; Wagner, R, 2004) |
| " The in vitro halothane-caffeine contracture tests are the most reliable method of identifying individuals susceptible to MH." | 3.67 | The association between the neuroleptic malignant syndrome and malignant hyperthermia. ( Adamantidis, MM; Adnet, PJ; Adnet-Bonte, CA; Dupuis, BA; Haudecoeur, G; Krivosic-Horber, RM; Saulnier, F, 1989) |
| "Effects of N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7), chlorpromazine, prenylamine and N2-dansyl-L-arginine-4-t-butylpiperidine amide on vascular smooth muscle contraction were compared by using helically cut strips of rabbit aorta." | 3.66 | Effects of various calmodulin antagonists on contraction of rabbit aortic strips. ( Asano, M; Hidaka, H; Suzuki, Y, 1982) |
| " Dantrolene, a muscle contraction antagonist, and MI-65-S, a muscle spindle suppressant, significantly delayed THE." | 3.65 | Blockade of the tonic hindlimb extensor component of maximal electroshock and pentylenetetrazol-induced seizures by drugs acting on muscle and muscle spindle systems: a perspective on method. ( Anderson, RJ; Britton, LW; Helke, CJ; Iadarola, MJ; Raines, A, 1976) |
| "In both the CPZ-treated and nontreated groups, ischemia induced a decline in muscle glycogen content, with a corresponding increase in muscle lactate and a decrease in mitochondrial respiratory control ratio." | 1.32 | Lack of chlorpromazine effect on skeletal muscle metabolism after ischemia and a short reperfusion period. ( Cherri, J; Massuda, CA; Piccinato, CE; Salles Roselino, JE, 2004) |
| "Chlorpromazine (CPZ) was reported to influence the functions of the sarcoplasmic reticulum (SR)." | 1.31 | [Effects of chlorpromazine on the skeletal muscle--a study using skinned single fibers of the guinea pig]. ( Yoshida, K, 2000) |
| " In comparison with surgical denervation, CPZ produced a similar increase in the maximum response but less leftward shift of the dose-response curves to norepinephrine." | 1.27 | Postjunctional supersensitivity of the smooth muscle of the rat vas deferens induced by calmodulin-antagonizing drugs applied locally to the hypogastric plexus. ( Goto, K, 1983) |
| "This chlorpromazine effect was used to determine if gallbladder agonists act through different intracellular mechanisms." | 1.27 | Effect of chlorpromazine (CPZ) on cholecystokinin-induced gallbladder contraction: the role of calcium. ( Davison, JS; Pomeranz, IS; Shaffer, EA, 1988) |
| "Pentobarbital and Sulpiride produce a biphasyc effect of opposite sign: at small doses Pentobarbital increases the stretch response while Sulpiride reduces it." | 1.26 | [Action of some psychotropic drugs on the electrmyographic response evoked by stretches of the gastrocnemius muscle of rats submitted to stress]. ( Eandi, M; Ricci Gamalero, S; Taglia, P, 1980) |
| " Dose-response curves were established for the blockade of ICSS by the antipsychotic drugs chlorpromazine, thioridazine, clozapine, and pimozide and the alpha-antagonist phenoxybenzamine." | 1.26 | Blockade of intracranial self-stimulation by antipsychotic drugs: failure to correlate with central alpha-noradrenergic blockade. ( Setler, P; Weidley, E; Zarevics, P, 1977) |
| " CPZ moved the dose-response curves to the right and depressed maximal responses." | 1.26 | Influence of chlorpromazine on calcium movements and contractile responses of guinea-pig ileum longitudinal smooth muscle to agonists. ( Chaturvedi, AK; Landon, EJ; Rama Sastry, BV, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 106 (88.33) | 18.7374 |
| 1990's | 6 (5.00) | 18.2507 |
| 2000's | 5 (4.17) | 29.6817 |
| 2010's | 2 (1.67) | 24.3611 |
| 2020's | 1 (0.83) | 2.80 |
| Authors | Studies |
|---|---|
| Hernández-Romero, Y | 1 |
| Rojas, JI | 1 |
| Castillo, R | 1 |
| Rojas, A | 1 |
| Mata, R | 1 |
| Obara, K | 1 |
| Matsuoka, Y | 1 |
| Iwata, N | 1 |
| Abe, Y | 1 |
| Ikegami, Y | 1 |
| Shioda, N | 1 |
| Hattori, Y | 1 |
| Hamamatsu, S | 1 |
| Yoshioka, K | 1 |
| Yamaki, F | 1 |
| Matsuo, K | 1 |
| Yoshio, T | 1 |
| Tanaka, Y | 1 |
| Vecherskiĭ, IuIu | 1 |
| Andreev, SL | 1 |
| Zatolokin, VV | 1 |
| Gusakova, SV | 1 |
| Kovalev, IV | 2 |
| Eremenko, KV | 1 |
| Dronova, IV | 1 |
| Alemán, V | 1 |
| Morales, E | 1 |
| Young, JM | 1 |
| Shimada, AL | 1 |
| Lino-Dos-Santos-Franco, A | 1 |
| Bolonheis, SM | 1 |
| Nakasato, A | 1 |
| Damazo, AS | 1 |
| Tavares-de-Lima, W | 1 |
| Farsky, SH | 1 |
| CALDEYRO-BARCIA, R | 1 |
| POSEIRO, JJ | 1 |
| ALVAREZ, H | 1 |
| TOST, P | 1 |
| NAKAZAWA, T | 2 |
| BARDOS, A | 1 |
| ROSENBLUM, W | 1 |
| SWEIFACH, BW | 1 |
| ACKER, CW | 1 |
| Wagner, R | 1 |
| Fink, RH | 1 |
| Stephenson, DG | 1 |
| Piccinato, CE | 1 |
| Salles Roselino, JE | 1 |
| Massuda, CA | 1 |
| Cherri, J | 1 |
| Goto, K | 1 |
| Baskakov, MB | 1 |
| Medvedev, MA | 1 |
| Larionov, NP | 1 |
| Takagi, A | 2 |
| Barron, JT | 1 |
| Bárány, M | 1 |
| Bárány, K | 1 |
| Storti, RV | 1 |
| Hershkowitz, N | 1 |
| Mahany, TM | 1 |
| Raines, A | 2 |
| Sporn, P | 1 |
| Asano, M | 2 |
| Suzuki, Y | 1 |
| Hidaka, H | 2 |
| Itoh, T | 1 |
| Kuriyama, H | 1 |
| Suzuki, H | 1 |
| Kerrick, WG | 1 |
| Hoar, PE | 1 |
| Cassidy, PS | 1 |
| Eandi, M | 1 |
| Ricci Gamalero, S | 1 |
| Taglia, P | 1 |
| Lorković, H | 2 |
| Jäger, U | 1 |
| Sokabe, M | 1 |
| Hasegawa, N | 1 |
| Yamamori, K | 1 |
| Koizumi, T | 1 |
| Yoshida, K | 1 |
| Coscia, L | 1 |
| Causa, P | 1 |
| Giuliani, E | 1 |
| Nunziata, A | 1 |
| Jaques, R | 1 |
| Naito, J | 1 |
| Kuga, T | 1 |
| Zarevics, P | 1 |
| Weidley, E | 1 |
| Setler, P | 1 |
| Finkbeiner, AE | 1 |
| Bissada, NK | 1 |
| Helke, CJ | 1 |
| Iadarola, MJ | 1 |
| Britton, LW | 1 |
| Anderson, RJ | 1 |
| Radomirov, R | 1 |
| Petkov, V | 1 |
| Nakanishi, H | 1 |
| Kaneko, M | 1 |
| Tilson, HA | 1 |
| Cabe, PA | 1 |
| Chaturvedi, AK | 1 |
| Landon, EJ | 1 |
| Rama Sastry, BV | 1 |
| Ferko, AP | 2 |
| Frederickson, RC | 1 |
| Hewes, CR | 1 |
| Aiken, JW | 1 |
| Murakami, W | 1 |
| Shibata, S | 4 |
| van Heiningen, PN | 1 |
| Batink, HD | 1 |
| van Zwieten, PA | 1 |
| Kimura, M | 2 |
| Kimura, I | 2 |
| Kondoh, T | 2 |
| Tsuneki, H | 2 |
| Flaim, SF | 1 |
| Brannan, MD | 1 |
| Swigart, SC | 1 |
| Gleason, MM | 1 |
| Muschek, LD | 1 |
| Adnet, PJ | 1 |
| Krivosic-Horber, RM | 1 |
| Adamantidis, MM | 1 |
| Haudecoeur, G | 1 |
| Adnet-Bonte, CA | 1 |
| Saulnier, F | 1 |
| Dupuis, BA | 1 |
| Taukulis, HK | 1 |
| Brake, LD | 1 |
| Ogawa, Y | 1 |
| Kurebayashi, N | 1 |
| Ozaki, H | 1 |
| Karaki, H | 1 |
| Nagase, H | 1 |
| Urakawa, N | 1 |
| Azuma, H | 1 |
| Nakajima, T | 1 |
| Martin, RE | 1 |
| Donahue, MJ | 1 |
| Nedergaard, OA | 1 |
| Abrahamsen, J | 1 |
| Pomeranz, IS | 2 |
| Davison, JS | 2 |
| Shaffer, EA | 2 |
| Nasu, T | 1 |
| Ishida, Y | 1 |
| Bonetto, R | 1 |
| Arany, E | 1 |
| del Castillo, E | 1 |
| Uranga, J | 1 |
| St George, C | 1 |
| Singhal, PC | 1 |
| Scharschmidt, LA | 1 |
| Gibbons, N | 1 |
| Hays, RM | 1 |
| Geter, RK | 1 |
| Winters, RR | 1 |
| Puckett, CL | 1 |
| Nagai, H | 1 |
| Yamada, H | 1 |
| Goto, S | 1 |
| Inagaki, N | 1 |
| Koda, A | 1 |
| Matsubara, S | 1 |
| Omori, T | 1 |
| Frankhuyzen, AL | 1 |
| Bonta, IL | 1 |
| Singh, KP | 1 |
| Baltzer, V | 1 |
| Bein, HJ | 1 |
| Pascoe, JE | 1 |
| Majumdar, DK | 1 |
| Zipf, HF | 1 |
| Hamacher, J | 1 |
| Balzer, H | 2 |
| Hellenbrecht, D | 3 |
| Martel, RR | 1 |
| Strand, FL | 1 |
| Stoboy, H | 1 |
| Chang, CC | 1 |
| Chuang, ST | 1 |
| Oye, I | 1 |
| Langslet, A | 4 |
| Méhes, J | 1 |
| Decsi, L | 1 |
| Várszegi, MK | 1 |
| Hideg, H | 1 |
| Hankovszky, OH | 1 |
| Fielden, R | 1 |
| Green, AL | 1 |
| Carrier, O | 2 |
| Hrdina, P | 1 |
| Garattini, S | 1 |
| Frankenheim, J | 1 |
| Scriabine, A | 2 |
| Moore, PF | 2 |
| Iorio, LC | 2 |
| Goldman, IM | 1 |
| McShane, WK | 1 |
| Booher, KD | 1 |
| Leszkovszky, GP | 1 |
| Korbonits, D | 1 |
| Janssen, PA | 1 |
| Niemegeers, CJ | 1 |
| Schellekens, KH | 1 |
| Dresse, A | 1 |
| Lenaerts, FM | 1 |
| Pinchard, A | 1 |
| Schaper, WK | 1 |
| van Nueten, JM | 1 |
| Verbruggen, FJ | 1 |
| György, L | 1 |
| Pfeifer, AK | 1 |
| Dóda, M | 1 |
| Galambos, E | 1 |
| Molnár, J | 1 |
| Kraiss, G | 1 |
| Nádor, K | 1 |
| Jacoby, HI | 1 |
| Marshall, CH | 1 |
| Godfraind, T | 3 |
| Kaba, A | 3 |
| Faeder, IR | 1 |
| O'Brien, RD | 1 |
| Kelkar, VV | 1 |
| Doctor, RB | 1 |
| Jindal, MN | 1 |
| Tarakhovskii, ML | 1 |
| Bennett, JM | 1 |
| Andersson, KE | 2 |
| Yamabe, S | 1 |
| Suzuki, A | 1 |
| Matsumoto, H | 1 |
| Bieger, D | 2 |
| Larochelle, L | 1 |
| Hornykiewicz, O | 1 |
| Kania, BF | 1 |
| Teuchmann, JK | 1 |
| Takikita, A | 1 |
| Simionescu, S | 1 |
| Daniel, B | 1 |
| Stancu, C | 1 |
| Hodgson, BJ | 1 |
| Daniel, EE | 1 |
| Maeda, T | 1 |
| Caprino, L | 1 |
| Borrelli, F | 1 |
| Falchetti, R | 1 |
| Capetola, R | 1 |
| Calesnick, B | 1 |
| Lomax, P | 1 |
| Kirkpatrick, WE | 1 |
| Ellis, KO | 1 |
| Carpenter, JF | 1 |
| Muller, P | 1 |
| Seeman, P | 1 |
| Spero, L | 1 |
| Cremer, JE | 1 |
| Bligh, J | 1 |
| Kim, ND | 1 |
| Bailey, LE | 1 |
| Dresel, PE | 1 |
| Ueki, S | 1 |
| Watanabe, S | 1 |
| Morimot, Y | 1 |
| Masuda, M | 1 |
| Ryg, M | 1 |
| Prindle, KH | 1 |
| Gold, HK | 1 |
| Cardon, PV | 1 |
| Epstein, SE | 1 |
| Mitolo-Chieppa, D | 1 |
| Dow, RW | 1 |
| Fry, WJ | 1 |
| Frankenheim, JM | 1 |
| Agarwal, SL | 1 |
| Bhargava, V | 1 |
| Bittar, EE | 1 |
4 reviews available for chlorpromazine and Muscle Contraction
| Article | Year |
|---|---|
[Physiology and biochemistry of muscle fibers and the effect of disease. Skinned fiber technic].
Topics: Biomechanical Phenomena; Chlorpromazine; Cytological Techniques; Humans; Malignant Hyperthermia; Mus | 1982 |
[Kinetic analysis of drug disposition and biological response].
Topics: Analgesics, Non-Narcotic; Animals; Body Temperature; Body Temperature Regulation; Chlorpromazine; Di | 2000 |
The role of calcium in the action of drugs on vascular smooth muscle.
Topics: Animals; Aorta; Calcium; Calcium Isotopes; Chlorpromazine; Cinnamates; In Vitro Techniques; Muscle C | 1972 |
Body-temperature and responses to drugs.
Topics: Acetylcholine; Anesthetics; Animals; Body Temperature; Body Temperature Regulation; Cats; Chlorproma | 1969 |
116 other studies available for chlorpromazine and Muscle Contraction
| Article | Year |
|---|---|
Spasmolytic effects, mode of action, and structure-activity relationships of stilbenoids from Nidema boothii.
Topics: Animals; Bibenzyls; Brain; Cattle; Dose-Response Relationship, Drug; Flavonoids; Guaiacol; Guinea Pi | 2004 |
Inhibitory Effects of Antipsychotics on the Contractile Response to Acetylcholine in Rat Urinary Bladder Smooth Muscles.
Topics: Acetylcholine; Aging; Animals; Antipsychotic Agents; Chlorpromazine; Cholinergic Antagonists; Clozap | 2021 |
[In vitro study of the radial artery vasodilatory reactions].
Topics: Chlorpromazine; Dopamine Antagonists; Heparin; Humans; Muscle Contraction; Muscle, Smooth; Nifedipin | 2014 |
On the nature of the interaction between chlorpromazine and the muscarinic receptor.
Topics: Animals; Binding, Competitive; Carbachol; Chlorpromazine; Cholinergic Agonists; Dose-Response Relati | 1981 |
In vivo hydroquinone exposure causes tracheal hyperresponsiveness due to TNF secretion by epithelial cells.
Topics: Animals; Chlorpromazine; Dose-Response Relationship, Drug; Hydroquinones; Male; Mast Cells; Methacho | 2012 |
The action of chlorpromazine on uterine contractility and arterial pressure in normal and toxemic pregnant women.
Topics: Blood Pressure; Blood Pressure Determination; Chlorpromazine; Female; Humans; Muscle Contraction; Pr | 1958 |
Effects of chlorpromazine and related substances on the contractility of oligodendrocytes.
Topics: Central Nervous System; Chlorpromazine; Muscle Contraction; Oligodendroglia | 1960 |
[Contribution to the study of the contractility of the uterus after long-term application of small doses of chlorpromazine and reserpine].
Topics: Chlorpromazine; Female; Humans; Muscle Contraction; Reserpine; Uterus | 1962 |
THE EFFECT OF TRANQUILIZERS ON THE CONTRACTILE RESPONSE OF CEREBRAL ARTERIES.
Topics: Acetylcholine; Atropine; Barium; Cerebral Arteries; Cerebrovascular Circulation; Chlorides; Chlorpro | 1964 |
AN INVESTIGATION OF THE VARIABILITY IN REPEATED PSYCHOPHYSIOLOGICAL MEASUREMENTS IN TRANQUILIZED MENTAL PATIENTS.
Topics: Blood Pressure; Chlorpromazine; Drug Therapy; Galvanic Skin Response; Heart; Heart Rate; Humans; Men | 1964 |
Effects of chlorpromazine and serotonin on the contractility of oligodendrocytes.
Topics: Chlorpromazine; Muscle Contraction; Neuroglia; Oligodendroglia; Serotonin | 1960 |
Effects of chlorpromazine on excitation-contraction coupling events in fast-twitch skeletal muscle fibres of the rat.
Topics: Algorithms; Animals; Antipsychotic Agents; Calcium Channel Blockers; Chlorpromazine; Dose-Response R | 2004 |
Lack of chlorpromazine effect on skeletal muscle metabolism after ischemia and a short reperfusion period.
Topics: Animals; Chlorpromazine; Disease Models, Animal; Dogs; Glycogen; Hydrogen-Ion Concentration; Ischemi | 2004 |
Postjunctional supersensitivity of the smooth muscle of the rat vas deferens induced by calmodulin-antagonizing drugs applied locally to the hypogastric plexus.
Topics: Animals; Calcium-Binding Proteins; Calmodulin; Chlorpromazine; Dose-Response Relationship, Drug; Ele | 1983 |
[Study of electromechanical coupling in smooth muscle cells of the ureter using phenothiazines].
Topics: Animals; Calmodulin; Chlorpromazine; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Muscle, S | 1984 |
Reversible phosphorylation and dephosphorylation of the 20,000-dalton light chain of myosin during the contraction-relaxation-contraction cycle of arterial smooth muscle.
Topics: Animals; Calcium; Carotid Arteries; Chlorpromazine; Egtazic Acid; Muscle Contraction; Muscle Relaxat | 1980 |
Effects of carbamazepine on muscle tone in the decerebrate cat.
Topics: Animals; Carbamazepine; Cats; Chlorpromazine; Decerebrate State; Electric Stimulation; Female; Male; | 1983 |
[Malignant hyperthermia-results of familial investigations in Austria (author's transl)].
Topics: Adenosine Triphosphate; Austria; Caffeine; Calcium; Chlorpromazine; Creatine Kinase; Halothane; Huma | 1981 |
Effects of various calmodulin antagonists on contraction of rabbit aortic strips.
Topics: Animals; Aorta, Thoracic; Calcium-Binding Proteins; Calmodulin; Chlorpromazine; Diamines; Female; In | 1982 |
Effects of chlorpromazine on the electrical and mechanical properties of intact and skinned muscle cells of guinea-pig mesenteric artery.
Topics: Animals; Calcium; Calmodulin; Chlorpromazine; Drug Interactions; Electrophysiology; Female; Guinea P | 1982 |
Biopharmacological assessment of calmodulin function: utility of calmodulin antagonist naphthalenesulfonamide.
Topics: Animals; Calcium-Binding Proteins; Calmodulin; Chlorpromazine; Diamines; In Vitro Techniques; Muscle | 1981 |
Chlorpromazine and skeletal muscle: a study of skinned single fibers of the guinea pig.
Topics: Animals; Calcium; Chlorpromazine; Foot; Guinea Pigs; Male; Muscle Contraction; Muscles; Sarcoplasmic | 1981 |
Calcium-activated tension: the role of myosin light chain phosphorylation.
Topics: Animals; Calcium; Chlorpromazine; Enzyme Activation; Muscle Contraction; Muscle, Smooth; Muscles; My | 1980 |
[Action of some psychotropic drugs on the electrmyographic response evoked by stretches of the gastrocnemius muscle of rats submitted to stress].
Topics: Amitriptyline; Animals; Chlorpromazine; Dextroamphetamine; Meprobamate; Muscle Contraction; Muscle R | 1980 |
Acetylcholine contractures of skeletal muscles: inhibition by chlorpromazine and diltiazem.
Topics: Acetylcholine; Animals; Chlorpromazine; Diltiazem; Female; Mice; Mice, Inbred BALB C; Muscle Contrac | 1995 |
Chlorpromazine and diltiazem effects in muscle: blockage of acetylcholine-evoked contractures, membrane currents and tracer calcium uptake.
Topics: Acetylcholine; Animals; Calcium; Calcium Channel Blockers; Chlorpromazine; Diltiazem; Dopamine Antag | 1996 |
Blockers and activators for stretch-activated ion channels of chick skeletal muscle.
Topics: Animals; Cells, Cultured; Chickens; Chlorpromazine; Ion Channel Gating; Ion Channels; Kanamycin; Mec | 1993 |
[Effects of chlorpromazine on the skeletal muscle--a study using skinned single fibers of the guinea pig].
Topics: Animals; Binding Sites; Calcium; Chlorpromazine; Dose-Response Relationship, Drug; Guinea Pigs; Huma | 2000 |
Pharmacological properties of new neuroleptic compounds.
Topics: Aggression; Amphetamine; Animals; Apomorphine; Avoidance Learning; Behavior, Animal; Blood Pressure; | 1975 |
Beta-adrenergic blocking agents as potent antagonists of mescaline-induced contractions in the rat uterus.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Amitriptyline; Animals; Chlorpromazine; Femal | 1976 |
[Pharmacological analysis of effects of perimetazine on isolated smooth muscle].
Topics: Acetylcholine; Animals; Antipsychotic Agents; Appendix; Barium; Chlorpromazine; Dose-Response Relati | 1976 |
Blockade of intracranial self-stimulation by antipsychotic drugs: failure to correlate with central alpha-noradrenergic blockade.
Topics: Animals; Antipsychotic Agents; Chlorpromazine; Clozapine; Depression, Chemical; Electric Stimulation | 1977 |
In vitro study of phenothiazine effects on urinary bladder.
Topics: Animals; Antipsychotic Agents; Chlorpromazine; Depression, Chemical; Guinea Pigs; In Vitro Technique | 1979 |
Blockade of the tonic hindlimb extensor component of maximal electroshock and pentylenetetrazol-induced seizures by drugs acting on muscle and muscle spindle systems: a perspective on method.
Topics: Animals; Anticonvulsants; Chlorpromazine; Dantrolene; Electroshock; Gallamine Triethiodide; Hindlimb | 1976 |
Nicotine-like effect of prostaglandin F2alpha on longitudinal smooth muscle of cat jejunum.
Topics: Animals; Cats; Chlorpromazine; Hexamethonium Compounds; In Vitro Techniques; Jejunum; Male; Muscle C | 1977 |
Is thioridazine-induced ejaculation failure peripheral in origin?
Topics: Animals; Chlorpromazine; Depression, Chemical; Ejaculation; Electric Stimulation; In Vitro Technique | 1978 |
Assessment of chemically-induced changes in the neuromuscular function of rats using a new recording grip meter.
Topics: Animals; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Male; Muscle Contraction; Neuromuscula | 1978 |
Influence of chlorpromazine on calcium movements and contractile responses of guinea-pig ileum longitudinal smooth muscle to agonists.
Topics: Animals; Calcium; Chlorpromazine; Drug Interactions; Guinea Pigs; Ileum; In Vitro Techniques; Male; | 1978 |
The inhibitory action of dopamine on the anterior tibialis muscle preparation antagonized by pimozide and chlorpromazine.
Topics: Animals; Blood Pressure; Cats; Chlorpromazine; Dopamine; Dopamine Antagonists; Drug Interactions; Ed | 1976 |
Correlation between the in vivo and an in vitro expression of opiate withdrawal precipitated by naloxone: their antagonism by l-(-)-delta9-tetrahydrocannabinol.
Topics: Acetylcholine; Animals; Chlorpromazine; Codeine; Dose-Response Relationship, Drug; Dronabinol; Femal | 1976 |
Evidence for a dopamine sensitive receptor in the young rat aorta.
Topics: Animals; Aorta, Thoracic; Chlorpromazine; Dopamine; Haloperidol; In Vitro Techniques; Isoproterenol; | 1976 |
Angiotensin II-induced increase in slowly exchanging 45Ca2+ in relation to contractile responses of rat and guinea-pig aorta.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Calcium; Calcium Channel Blockers; Calcium Radioisotopes; | 1991 |
Noncontractile acetylcholine receptor-operated Ca++ mobilization: suppression of activation by open channel blockers and acceleration of desensitization by closed channel blockers in mouse diaphragm muscle.
Topics: Aequorin; Animals; Anti-Ulcer Agents; Bupivacaine; Calcium; Calcium Channel Blockers; Chlorpromazine | 1991 |
Enhancing effect by nicotinic acetylcholine receptor channel blockers, including beta-eudesmol, on succinylcholine-induced inhibition of twitch tension and intracellular Ca++ in mouse diaphragm muscle.
Topics: Aequorin; Animals; Bupivacaine; Calcium; Chlorpromazine; Diaphragm; Dose-Response Relationship, Drug | 1991 |
Neuroleptic drugs attenuate calcium influx and tension development in rabbit thoracic aorta: effects of pimozide, penfluridol, chlorpromazine, and haloperidol.
Topics: Animals; Antipsychotic Agents; Aorta, Thoracic; Calcium; Calcium Channel Blockers; Chlorpromazine; H | 1985 |
The association between the neuroleptic malignant syndrome and malignant hyperthermia.
Topics: Adult; Caffeine; Chlorpromazine; Contracture; Disease Susceptibility; Female; Halothane; Humans; Mal | 1989 |
Therapeutic and hypothermic properties of diazepam altered by a diazepam-chlorpromazine association.
Topics: Animals; Anxiety; Behavior, Animal; Body Temperature; Chlorpromazine; Diazepam; Drug Administration | 1989 |
Modulations by drugs of the relationship between calcium binding to troponin C and tension.
Topics: Animals; Caffeine; Calcium; Calmodulin; Chlorpromazine; In Vitro Techniques; Isometric Contraction; | 1989 |
Divergent pharmacological effects of three calmodulin antagonists, N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7), chlorpromazine and calmidazolium, on isometric tension development and myosin light chain phosphorylation in intact bovine trachea
Topics: Animals; Atropine; Calmodulin; Carbachol; Cattle; Chlorpromazine; Imidazoles; In Vitro Techniques; M | 1989 |
Contractile effects of jellyfish toxin extracted from Carybdea rastonii on isolated rabbit aorta.
Topics: Animals; Aorta, Thoracic; Chlorpromazine; Cnidarian Venoms; Drug Interactions; In Vitro Techniques; | 1986 |
Correlation of myosin light chain phosphorylation and gamma aminobutyric acid receptors in Ascaris suum muscle.
Topics: Acetylcholine; Animals; Anthelmintics; Ascaris; Chlorpromazine; Female; gamma-Aminobutyric Acid; Ive | 1987 |
Effect of chlorpromazine on sympathetic neuroeffector transmission in the rabbit isolated pulmonary artery and aorta.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Chlorpromazine; Electric Stimulation; In Vit | 1988 |
Effect of chlorpromazine (CPZ) on cholecystokinin-induced gallbladder contraction: the role of calcium.
Topics: Animals; Bethanechol; Bethanechol Compounds; Calcium; Chlorpromazine; Cholecystokinin; Dose-Response | 1988 |
Effects of cadmium ions, D-600 and chlorpromazine on the skinned smooth muscle of guinea-pig taenia coli.
Topics: Animals; Biological Transport, Active; Cadmium; Chlorpromazine; Edetic Acid; Gallopamil; Guinea Pigs | 1986 |
Effect of glomerulopressin on several isolated veins and arteries of different species.
Topics: Animals; Arteries; Chlorpromazine; Cricetinae; Dogs; Glucuronates; Glucuronidase; Muscle Contraction | 1987 |
The effect of chlorpromazine on cholecystokinin induced gallbladder contraction.
Topics: Animals; Chlorpromazine; Cholecystokinin; Gallbladder; Guinea Pigs; In Vitro Techniques; Muscle Cont | 1987 |
Contraction and relaxation of cultured mesangial cells on a silicone rubber surface.
Topics: Angiotensin II; Animals; Cell Adhesion; Cells, Cultured; Chlorpromazine; Culture Media; Cytochalasin | 1986 |
Resolution of experimental microvascular spasm and improvement in anastomotic patency by direct topical agent application.
Topics: Administration, Topical; Animals; Chlorpromazine; Disease Models, Animal; Drug Evaluation; Epinephri | 1986 |
Reduction of antigen-induced contraction of sensitized guinea-pig tracheal smooth muscle in vitro by calmodulin inhibitors.
Topics: Animals; Antigens; Calmodulin; Chlorpromazine; Female; Guinea Pigs; Histamine; Imidazoles; Immunizat | 1985 |
Rapid cooling contracture in frog striated muscles treated with chlorpromazine and haloperidol.
Topics: Animals; Caffeine; Chlorpromazine; Cold Temperature; Dantrolene; Haloperidol; Muscle Contraction; Mu | 1985 |
Effect of mianserin, a potent anti-serotonin agent, on the isolated rat stomach fundus preparation.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Binding Sites; Calcium; Chlorpromazine; Cyproh | 1974 |
Cardiovascular effects of some phenothiazine derivatives following intracoronary injection in dogs.
Topics: Animals; Blood Pressure; Cardiac Catheterization; Cardiac Complexes, Premature; Chlorpromazine; Coro | 1969 |
Pharmacological investigations with benzoctamine (Tacitin), a new psycho-active agent.
Topics: Adjuvants, Anesthesia; Aggression; Animals; Anthracenes; Cats; Central Nervous System; Chlordiazepox | 1973 |
The effects of ethyl chloride on the muscle spindles of the triceps surae of the rabbit.
Topics: Animals; Chlorpromazine; Decerebrate State; Electrophysiology; Ethyl Chloride; In Vitro Techniques; | 1965 |
[Comparative studies on the effect of Veratrum alkaloids on cardiac contraction kinetics].
Topics: Acetylcholine; Biomechanical Phenomena; Bradycardia; Chloroform; Chlorpromazine; Depression, Chemica | 1967 |
[On the contraction unleashing effect of inhibitors of active calcium transport (chlorpromazine, prenylamine, reserpine) on the frog rectus and sartorius].
Topics: Animals; Anura; Biological Transport, Active; Calcium; Calcium Isotopes; Chlorpromazine; Depression, | 1968 |
[Influence of chlorpromazine, prenylamine, imipramine and reserpine on calcium exchange and muscle function (m. rectus and sartorius of frog)].
Topics: Acetylcholine; Animals; Anura; Biological Transport, Active; Calcium; Calcium Isotopes; Chlorpromazi | 1969 |
Stabilizing-labilizing effects of reserpine, chlorpromazine, tetracaine, and quinidine on frog skeletal muscle fibers.
Topics: Animals; Anura; Cell Membrane; Chlorides; Chlorpromazine; Membrane Potentials; Muscle Contraction; M | 1971 |
Nonequilibrium alpha adrenergic blockade and neuroleptic activity of N-ethoxycarbonyl-1,dihydroquinoline (BC-347).
Topics: Acetylcholine; Angiotensin II; Animals; Aorta; Avoidance Learning; Blood Pressure; Catalepsy; Cats; | 1969 |
Effect of hormones on muscle action potentials, contractions and temperature in rats.
Topics: Action Potentials; Adrenocorticotropic Hormone; Animals; Body Temperature; Chlorpromazine; Cold Temp | 1969 |
Effects of desipramine and imipramine on the nerve, muscle and synaptic transmission of rat diaphragms.
Topics: Acetylcholine; Action Potentials; Animals; Axons; Chlorpromazine; Desipramine; Diaphragm; Electric S | 1972 |
The role of cyclic AMP in the inotropic response to isoprenaline and glucagon.
Topics: Adenylyl Cyclase Inhibitors; Animals; Butyrates; Chlorpromazine; Cyclic AMP; Female; Glucagon; Heart | 1972 |
Inhibitory effect of 1-alkylbenzimidazoles on gastric secretion in the rat.
Topics: Acetylcholine; Animals; Behavior, Animal; Blood Pressure; Bradycardia; Carbachol; Cats; Central Nerv | 1966 |
A comparison of aralkylamines and aralkylguanidines as antagonists of adrenergic neurone blockade.
Topics: Amines; Amphetamine; Animals; Blepharoptosis; Cats; Chlorpromazine; Choline; Drug Antagonism; Electr | 1966 |
Antagonizing action of chlorpromazine, dibenamine, and phenoxybenzamine on potassium-induced contraction.
Topics: Angiotensin II; Animals; Aorta; Calcium; Calcium Isotopes; Chlorpromazine; Dibenzylchlorethamine; Dr | 1967 |
Effect of desipramine on the depolarized isolated renal artery.
Topics: Animals; Calcium; Chlorpromazine; Cocaine; Desipramine; Electrophysiology; Muscle Contraction; Pheno | 1967 |
Effect of chlorpromazine, dibenamine and phenoxybenzamine on the contractile response of taenia coli to potassium, acetylcholine, angiotensin and barium.
Topics: Acetylcholine; Angiotensin II; Animals; Barium; Calcium; Calcium Isotopes; Chlorpromazine; Colon; Di | 1968 |
Quinterenol, a new beta adrenergic stimulant.
Topics: Acetylcholine; Anaphylaxis; Animals; Blood Pressure; Cardiac Output; Cats; Chlorpromazine; Dogs; Fem | 1968 |
[On the pharmacology of new isoquinoline derivatives].
Topics: Anesthetics, Local; Animals; Antihypertensive Agents; Atropine; Barbiturates; Blood Pressure; Centra | 1967 |
Pimozide, a chemically novel, highly potent and orally long-acting neuroleptic drug. I. The comparative pharmacology of pimozide, haloperidol, and chlorpromazine.
Topics: Amphetamine; Animals; Apomorphine; Behavior, Animal; Benzimidazoles; Blepharoptosis; Body Temperatur | 1968 |
Pharmacology of new tropine ethers with central activity.
Topics: Acetylcholine; Anesthetics, Local; Animals; Anura; Behavior, Animal; Blood Pressure; Brain Chemistry | 1968 |
Gastric motor-stimulating activity of gastrin tetrapeptide in dogs.
Topics: Animals; Atropine; Blood Pressure; Carbachol; Chlorpromazine; Colon; Dogs; Duodenum; Gastrins; Gastr | 1969 |
Inhibition by cinnarizine and chlorpromazine of the contraction induced by calcium and adrenaline in vascular smooth muscle.
Topics: Animals; Calcium; Chlorpromazine; Epinephrine; Histamine H1 Antagonists; In Vitro Techniques; Mesent | 1969 |
Blockade or reversal of the contraction induced by calcium and adrenaline in depolarized arterial smooth muscle.
Topics: Animals; Calcium; Chlorpromazine; Epinephrine; Histamine H1 Antagonists; In Vitro Techniques; Mesent | 1969 |
Responses of perfused isolated leg preparations of the cockroach, Gromphadorhina portentosa, to L-glutamate, gaba, picrotoxin, strychnine and chlorpromazine.
Topics: Aminobutyrates; Animals; Chlorpromazine; Forelimb; Glutamates; Insecta; Muscle Contraction; Neuromus | 1970 |
Unique beta adrenergic stimulation and blockade by quinterenol.
Topics: Adrenergic beta-Agonists; Amino Alcohols; Animals; Chlorpromazine; Drug Antagonism; Female; Heart At | 1971 |
Chlorpromazine-induced contracture of frog rectus abdominis muscle.
Topics: Acetylcholine; Adenosine; Animals; Arsenic; Atropine; Caffeine; Chlorpromazine; Choline; Cocaine; Cy | 1974 |
Role of sulfhydryl groups in the mechanism of uterine contraction in response to stimulation of cholinergic and serotoninergic receptors.
Topics: Animals; Barium; Cadmium; Chlorpromazine; Female; Morphine; Muscle Contraction; Procaine; Quinuclidi | 1974 |
Modification of strychnine-induced convulsions by anticonvulsants in the frog.
Topics: Animals; Anticonvulsants; Anura; Chlorpromazine; Mephenesin; Muscle Contraction; Orphenadrine; Rana | 1972 |
Effects of chlorpromazine, imipramine, and quinidine on the mechanical activity of single skeletal muscle fibres of the frog.
Topics: Animals; Anura; Caffeine; Chlorpromazine; Drug Synergism; Electric Stimulation; Imipramine; Methods; | 1972 |
Inhibition of K-induced tonic contraction in vas deferens of guinea pig by chlorpromazine and its free radical.
Topics: Animals; Cerium; Chlorpromazine; Culture Media; Cysteine; Free Radicals; Guinea Pigs; Hydrogen-Ion C | 1974 |
A model for the quantitative study of central dopaminergic and serotoninergic activity.
Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Caudate Nucleus; Chlorpromazine; Dihydroxyphenylalanine; | 1972 |
Influence of striatal dopamine receptor blockade on a bulbar motor reaction.
Topics: Animals; Chlorpromazine; Corpus Striatum; Dextroamphetamine; Dihydroxyphenylalanine; Electric Stimul | 1974 |
[Studies on the peripheral action of chlorpromazine, reserpine, dehydrobenzperidol, azacyclonol, hydroxyzine, and xylazine].
Topics: Aniline Compounds; Animals; Chlorpromazine; Droperidol; Hydroxyzine; Muscle Contraction; Muscles; Pi | 1972 |
[Mechanism of catecholamine release in the excised guinea pig vas deferens, with special reference to the role of acetylcholine].
Topics: Acetylcholine; Animals; Atropine; Bretylium Compounds; Calcium; Catecholamines; Chlorpromazine; Elec | 1972 |
[Non-specific pharmacodynamic properties of chlorpromazine (CPZ) in relationship to the characteristic specific action of the drug].
Topics: Animals; Central Nervous System; Chlorpromazine; Chromaffin System; Dogs; Dose-Response Relationship | 1973 |
Effects of chlorpromazine, imipramine, and quinidine on action potential and tension development in single skeletal muscle fibres of the frog.
Topics: Action Potentials; Animals; Anura; Chlorpromazine; Dose-Response Relationship, Drug; Electric Stimul | 1973 |
Studies concerning the source of calcium for contraction of rat myometrium.
Topics: Acetylcholine; Action Potentials; Animals; Calcium; Calcium Radioisotopes; Carbon Radioisotopes; Chl | 1973 |
[Mode of action of spasmogens (K, acetylcholine, Ba) and antispasmodics (isoproterenol, papaverine, chlorpromazine) on excised vas deferens of the rabbit, with special reference to their relationship with Ca].
Topics: Acetylcholine; Animals; Barium; Calcium; Chlorpromazine; Dinitrophenols; In Vitro Techniques; Isopro | 1973 |
General pharmacological properties of 4,5-diphenyl-2-bis-(2-hydroxyethyl)-aminoxazol (ditazol).
Topics: Amphetamine; Animals; Anti-Inflammatory Agents; Atropine; Blood Pressure; Cats; Chlorpromazine; Etha | 1973 |
The inhibitory action of dopamine on the rat anterior tibialis muscle preparation.
Topics: Animals; Anura; Chlorpromazine; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Ed | 1974 |
Interactions of chlorpromazine with monoamines in the hypothalamic thermoregulatory centers.
Topics: Acetylcholine; Animals; Aorta; Biogenic Amines; Body Temperature; Body Temperature Regulation; Cereb | 1974 |
A comparative study of dantrolene sodium and other skeletal muscle relaxants with the Straub tail mouse.
Topics: Anesthetics, Local; Animals; Chlordiazepoxide; Chlorpromazine; Dantrolene; Diazepam; Gallamine Triet | 1974 |
The additive effects of tranquilizers and dopamine on smooth muscle.
Topics: Animals; Carbachol; Chlorpromazine; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Elec | 1974 |
Correlation of the subcellular distribution of digoxin with the positive inotropic effect.
Topics: Aldosterone; Animals; Carbon Isotopes; Cell Nucleus; Chlorpromazine; Chromatography, Gel; Digoxin; E | 1972 |
Effects of chlorpromazine, d,l-propranolol, and d-propranolol in the isolated rat heart: modification of the response to isoprenaline and glucagon.
Topics: Animals; Chlorpromazine; Drug Interactions; Enzyme Activation; Female; Glucagon; Heart; Heart Rate; | 1971 |
[General pharmacological effects of flupentixol].
Topics: Animals; Anti-Inflammatory Agents; Blood Pressure; Chlorpromazine; Dogs; Electrocardiography; Ethano | 1971 |
Effects of chlorpromazine and propranolol on left ventricular systolic pressure, ECG, and K + efflux in the isolated perfused rat heart.
Topics: Animals; Blood Pressure; Cell Membrane; Chlorpromazine; Electric Stimulation; Electrocardiography; G | 1971 |
Cardiac effects of antiparkinson drugs, local anesthetics, and tranquilizers.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Cell Membrane Permeability; Chlorpromazine; Coronary V | 1970 |
Effects of psychopharmacologic agents on myocardial contractility.
Topics: Animals; Cats; Chlordiazepoxide; Chlorides; Chlorpromazine; Diazepam; Heart; Lithium; Muscle Contrac | 1970 |
[Effects of 5-HT and its antagonists on contraction of the anterior tibial muscle in the rat].
Topics: Animals; Chlorpromazine; Cyproheptadine; Methysergide; Muscle Contraction; Phenoxybenzamine; Rats; S | 1968 |
Regulation of venous capacity: the carotid sinus mechanism.
Topics: Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Carotid Sinus; Chlorpromazine; Dogs | 1968 |
Effects of chlorpromazine, phenoxybenzamine, dibenamine and calcium on electrical and mechanical responses to potassium in guinea-pig taenia coli.
Topics: Acetylcholine; Animals; Calcium; Chlorpromazine; Dibenzylchlorethamine; Drug Antagonism; Electric Co | 1968 |
Some observations on the adrenergic blocking activity of desipramine and amitriptyline on aortic strips of rabbits.
Topics: Amitriptyline; Animals; Aorta; Calcium; Chlorpromazine; Desipramine; In Vitro Techniques; Male; Musc | 1969 |
Study of the effects of tranquillizers on the acetylcholine, 5 hydroxytryptamine, adrenaline and nor-adrenaline responses of the cardiac, smooth and skeletal muscle.
Topics: Acetylcholine; Animals; Anura; Chlorpromazine; Epinephrine; Guinea Pigs; Heart; Intestines; Meprobam | 1964 |
Effect of inhibitors and uncouplers on the Na pump of the Maia muscle fibre.
Topics: Animals; Anti-Bacterial Agents; Antimycin A; Biological Transport; Chlorpromazine; Crustacea; Electr | 1966 |