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chlorpromazine and Multiple Sclerosis

chlorpromazine has been researched along with Multiple Sclerosis in 7 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Multiple Sclerosis: An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)

Research Excerpts

ExcerptRelevanceReference
"To report a case of risperidone-induced Pisa syndrome in a patient with multiple sclerosis (MS) that resolved with lurasidone, recurred with chlorpromazine, and was complicated by possible drug-drug interactions."7.79Risperidone-induced Pisa syndrome in MS: resolution with lurasidone and recurrence with Chlorpromazine. ( Diefenderfer, LA; Iuppa, CA, 2013)
"To report a case of risperidone-induced Pisa syndrome in a patient with multiple sclerosis (MS) that resolved with lurasidone, recurred with chlorpromazine, and was complicated by possible drug-drug interactions."3.79Risperidone-induced Pisa syndrome in MS: resolution with lurasidone and recurrence with Chlorpromazine. ( Diefenderfer, LA; Iuppa, CA, 2013)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19905 (71.43)18.7374
1990's1 (14.29)18.2507
2000's0 (0.00)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Iuppa, CA1
Diefenderfer, LA1
SEYFFERT, HM1
BOCK, E1
BOCKOVA, V1
KELLY, R1
Bloch, M1
Gur, E1
Shalev, A1
Baykuschev, S1
Ambrozy, G1

Other Studies

7 other studies available for chlorpromazine and Multiple Sclerosis

ArticleYear
Risperidone-induced Pisa syndrome in MS: resolution with lurasidone and recurrence with Chlorpromazine.
    The Annals of pharmacotherapy, 2013, Volume: 47, Issue:9

    Topics: Adult; Antipsychotic Agents; Child Development Disorders, Pervasive; Chlorpromazine; Gait Ataxia; Hu

2013
[The effect of phenothiazine derivatives in multiple sclerosis].
    Munchener medizinische Wochenschrift (1950), 1955, Dec-02, Volume: 97, Issue:48

    Topics: Antipsychotic Agents; Autonomic Agents; Chlorpromazine; Multiple Sclerosis; Phenothiazines; Psychoth

1955
[Possibilities of a new method of symptomatic therapy of multiple sclerosis].
    Ceskoslovenska neurologie, 1959, Volume: 22

    Topics: Chlorpromazine; Humans; Hyaluronoglucosaminidase; Multiple Sclerosis; Psychotherapy, Multiple

1959
TREATMENT OF DISSEMINATED SCLEROSIS.
    Physiotherapy, 1963, Volume: 49

    Topics: Antidepressive Agents; Chlorpromazine; Electroconvulsive Therapy; Exercise Therapy; Humans; Mephenes

1963
Chlorpromazine prophylaxis of steroid-induced psychosis.
    General hospital psychiatry, 1994, Volume: 16, Issue:1

    Topics: Adult; Chlorpromazine; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Male;

1994
[The effect of chlorpromazine on inhibitory processes in the spinal cord of patients with spastic paralyses].
    Deutsche Zeitschrift fur Nervenheilkunde, 1968, Volume: 194, Issue:4

    Topics: Cerebrovascular Disorders; Chlorpromazine; Electromyography; Encephalitis; Humans; Motor Neurons; Mu

1968
[On tonic attacks].
    Psychiatria et neurologia, 1966, Volume: 151, Issue:3

    Topics: Adolescent; Adult; Barbiturates; Chlorpromazine; Electromyography; Encephalitis; Female; Humans; Mal

1966