chlorpromazine has been researched along with Multiple Sclerosis in 7 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Multiple Sclerosis: An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
Excerpt | Relevance | Reference |
---|---|---|
"To report a case of risperidone-induced Pisa syndrome in a patient with multiple sclerosis (MS) that resolved with lurasidone, recurred with chlorpromazine, and was complicated by possible drug-drug interactions." | 7.79 | Risperidone-induced Pisa syndrome in MS: resolution with lurasidone and recurrence with Chlorpromazine. ( Diefenderfer, LA; Iuppa, CA, 2013) |
"To report a case of risperidone-induced Pisa syndrome in a patient with multiple sclerosis (MS) that resolved with lurasidone, recurred with chlorpromazine, and was complicated by possible drug-drug interactions." | 3.79 | Risperidone-induced Pisa syndrome in MS: resolution with lurasidone and recurrence with Chlorpromazine. ( Diefenderfer, LA; Iuppa, CA, 2013) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 5 (71.43) | 18.7374 |
1990's | 1 (14.29) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (14.29) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Iuppa, CA | 1 |
Diefenderfer, LA | 1 |
SEYFFERT, HM | 1 |
BOCK, E | 1 |
BOCKOVA, V | 1 |
KELLY, R | 1 |
Bloch, M | 1 |
Gur, E | 1 |
Shalev, A | 1 |
Baykuschev, S | 1 |
Ambrozy, G | 1 |
7 other studies available for chlorpromazine and Multiple Sclerosis
Article | Year |
---|---|
Risperidone-induced Pisa syndrome in MS: resolution with lurasidone and recurrence with Chlorpromazine.
Topics: Adult; Antipsychotic Agents; Child Development Disorders, Pervasive; Chlorpromazine; Gait Ataxia; Hu | 2013 |
[The effect of phenothiazine derivatives in multiple sclerosis].
Topics: Antipsychotic Agents; Autonomic Agents; Chlorpromazine; Multiple Sclerosis; Phenothiazines; Psychoth | 1955 |
[Possibilities of a new method of symptomatic therapy of multiple sclerosis].
Topics: Chlorpromazine; Humans; Hyaluronoglucosaminidase; Multiple Sclerosis; Psychotherapy, Multiple | 1959 |
TREATMENT OF DISSEMINATED SCLEROSIS.
Topics: Antidepressive Agents; Chlorpromazine; Electroconvulsive Therapy; Exercise Therapy; Humans; Mephenes | 1963 |
Chlorpromazine prophylaxis of steroid-induced psychosis.
Topics: Adult; Chlorpromazine; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Male; | 1994 |
[The effect of chlorpromazine on inhibitory processes in the spinal cord of patients with spastic paralyses].
Topics: Cerebrovascular Disorders; Chlorpromazine; Electromyography; Encephalitis; Humans; Motor Neurons; Mu | 1968 |
[On tonic attacks].
Topics: Adolescent; Adult; Barbiturates; Chlorpromazine; Electromyography; Encephalitis; Female; Humans; Mal | 1966 |