Page last updated: 2024-10-25

chlorpromazine and Mouth Neoplasms

chlorpromazine has been researched along with Mouth Neoplasms in 3 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Mouth Neoplasms: Tumors or cancer of the MOUTH.

Research Excerpts

ExcerptRelevanceReference
"In this study, treatment of human oral cancer cells with CPZ inhibited their proliferation and induced G2/M phase arrest."1.62Chlorpromazine, an antipsychotic agent, induces G2/M phase arrest and apoptosis via regulation of the PI3K/AKT/mTOR-mediated autophagy pathways in human oral cancer. ( Chang, HC; Han, KF; Hung, CC; Jhou, AJ; Lai, YW; Lee, CH; Lee, YC; Lin, HC; Lin, MY; Liu, WT, 2021)
"A 57-year-old schizoaffective disorder patient was placed on chlorpromazine because of its sedative properties and low profile for extrapyramidal side effects."1.29Cutaneous and ocular changes associated with the use of chlorpromazine. ( Berk, MA; Mosnaim, AD; Richer, S; Wolf, ME, 1993)
"Twenty-nine patients with advanced mouth cancer have completed a course of this treatment, of whom five of nine were free of disease after 2 years and 10 of 21 at 1 year, with three intercurrent deaths."1.27A feasibility study of a new approach to clinical radiosensitisation: hypothermia and hyperbaric oxygen in combination with pharmacological vasodilatation. ( Barry, L; Blekkenhorst, G; Boniaszczuk, J; Fataar, AB; Gregory, A; Harrison, GG; Hering, ER; Korrubel, J; Morrell, D; Sealy, R, 1986)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Jhou, AJ1
Chang, HC1
Hung, CC1
Lin, HC1
Lee, YC1
Liu, WT1
Han, KF1
Lai, YW1
Lin, MY1
Lee, CH1
Wolf, ME1
Richer, S1
Berk, MA1
Mosnaim, AD1
Sealy, R1
Harrison, GG1
Morrell, D1
Korrubel, J1
Gregory, A1
Barry, L1
Blekkenhorst, G1
Hering, ER1
Fataar, AB1
Boniaszczuk, J1

Other Studies

3 other studies available for chlorpromazine and Mouth Neoplasms

ArticleYear
Chlorpromazine, an antipsychotic agent, induces G2/M phase arrest and apoptosis via regulation of the PI3K/AKT/mTOR-mediated autophagy pathways in human oral cancer.
    Biochemical pharmacology, 2021, Volume: 184

    Topics: Animals; Antineoplastic Agents; Antipsychotic Agents; Autophagy; Cell Line, Tumor; Chlorpromazine; E

2021
Cutaneous and ocular changes associated with the use of chlorpromazine.
    International journal of clinical pharmacology, therapy, and toxicology, 1993, Volume: 31, Issue:8

    Topics: Carcinoma, Basal Cell; Chlorpromazine; Drug Eruptions; Eye Diseases; Humans; Male; Middle Aged; Mout

1993
A feasibility study of a new approach to clinical radiosensitisation: hypothermia and hyperbaric oxygen in combination with pharmacological vasodilatation.
    The British journal of radiology, 1986, Volume: 59, Issue:707

    Topics: Anesthesia, Intravenous; Carcinoma, Squamous Cell; Chlorpromazine; Feasibility Studies; Humans; Hype

1986