Page last updated: 2024-10-25

chlorpromazine and Metabolic Diseases

chlorpromazine has been researched along with Metabolic Diseases in 5 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Metabolic Diseases: Generic term for diseases caused by an abnormal metabolic process. It can be congenital due to inherited enzyme abnormality (METABOLISM, INBORN ERRORS) or acquired due to disease of an endocrine organ or failure of a metabolically important organ such as the liver. (Stedman, 26th ed)

Research Excerpts

ExcerptRelevanceReference
"Pyridoxine has been reported as having an antilactogenic effect, presumably by suppressing prolactin secretion."2.64Failure of pyridoxine to suppress raised serum prolactin levels. ( de Waal, JM; Harms, JH; Pannall, PR; Slabber, CF; Steyn, AF, 1978)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lange, JH1
Reinders, JH1
Tolboom, JT1
Glennon, JC1
Coolen, HK1
Kruse, CG1
WOOLLEY, DW1
VANDERHOEVEN, T1
de Waal, JM1
Steyn, AF1
Harms, JH1
Slabber, CF1
Pannall, PR1
Zimmerman, HJ1
Lambotte, L1
Rocmans, P1

Trials

1 trial available for chlorpromazine and Metabolic Diseases

ArticleYear
Failure of pyridoxine to suppress raised serum prolactin levels.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1978, Feb-25, Volume: 53, Issue:8

    Topics: Chlorpromazine; Female; Galactorrhea; Humans; Lactation; Metabolic Diseases; Pregnancy; Prolactin; P

1978

Other Studies

4 other studies available for chlorpromazine and Metabolic Diseases

ArticleYear
Principal component analysis differentiates the receptor binding profiles of three antipsychotic drug candidates from current antipsychotic drugs.
    Journal of medicinal chemistry, 2007, Oct-18, Volume: 50, Issue:21

    Topics: Antipsychotic Agents; Basal Ganglia Diseases; Benzoxazines; Biogenic Monoamines; Humans; Hyperprolac

2007
SEROTONIN DEFICIENCY IN INFANCY AS ONE CAUSE OF A MENTAL DEFECT IN PHENYLKETONURIA.
    Science (New York, N.Y.), 1964, May-15, Volume: 144, Issue:3620

    Topics: Animals; Animals, Newborn; Behavior; Catecholamines; Chlorpromazine; Genetics; Learning; Metabolic D

1964
The spectrum of hepatotoxicity.
    Perspectives in biology and medicine, 1968,Autumn, Volume: 12, Issue:1

    Topics: Aminosalicylic Acids; Anti-Bacterial Agents; Antimetabolites; Benzene Derivatives; Carbon Tetrachlor

1968
[Toxi-infectious shock].
    Acta chirurgica Belgica, 1973, Volume: 72, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; Blood Transfusion; Chlorpromazine; Digitalis G

1973