chlorpromazine has been researched along with MODS in 2 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chlorpromazine mitigates the development of zymosan-induced MODS, possibly by reducing macrophage TNF-alpha production." | 3.70 | Chlorpromazine down-regulates tumor necrosis factor-alpha and attenuates experimental multiple organ dysfunction syndrome in mice. ( Goris, RJ; Hendriks, T; Jansen, MJ; Knapen, MF; van der Meer, JW; van Kempen, LC, 1998) |
| "Drug-induced agranulocytosis (DIA) is a potentially fatal disorder." | 1.31 | Hematopoietic growth factors in drug-induced agranulocytosis. ( Pavithran, K; Thomas, M, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pavithran, K | 1 |
| Thomas, M | 1 |
| Jansen, MJ | 1 |
| Hendriks, T | 1 |
| Knapen, MF | 1 |
| van Kempen, LC | 1 |
| van der Meer, JW | 1 |
| Goris, RJ | 1 |
2 other studies available for chlorpromazine and MODS
| Article | Year |
|---|---|
Hematopoietic growth factors in drug-induced agranulocytosis.
Topics: Adolescent; Adult; Agranulocytosis; Chlorpromazine; Dapsone; Dipyrone; Female; Granulocyte-Macrophag | 2002 |
Chlorpromazine down-regulates tumor necrosis factor-alpha and attenuates experimental multiple organ dysfunction syndrome in mice.
Topics: Animals; Chlorpromazine; Disease Models, Animal; Down-Regulation; Drug Administration Schedule; Immu | 1998 |