chlorpromazine has been researched along with Liver Cirrhosis, Biliary in 14 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Liver Cirrhosis, Biliary: FIBROSIS of the hepatic parenchyma due to obstruction of BILE flow (CHOLESTASIS) in the intrahepatic or extrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC; BILE DUCTS, EXTRAHEPATIC). Primary biliary cholangitis involves the destruction of small intra-hepatic bile ducts and decreased bile secretion. Secondary biliary cholangitis is produced by prolonged obstruction of large intrahepatic or extrahepatic bile ducts from a variety of causes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We describe a 33-yr-old pregnant woman in whom a primary biliary cirrhosis-like syndrome developed after 2 wk of chlorpromazine therapy." | 7.69 | Chlorpromazine-induced vanishing bile duct syndrome leading to biliary cirrhosis. ( Altorfer, J; Flury, R; Greminger, P; Jost, R; Meyenberger, C; Moradpour, D; Schmid, M, 1994) |
| "We describe a 33-yr-old pregnant woman in whom a primary biliary cirrhosis-like syndrome developed after 2 wk of chlorpromazine therapy." | 3.69 | Chlorpromazine-induced vanishing bile duct syndrome leading to biliary cirrhosis. ( Altorfer, J; Flury, R; Greminger, P; Jost, R; Meyenberger, C; Moradpour, D; Schmid, M, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (92.86) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| MYERS, JD | 1 |
| OLSON, RE | 1 |
| LEWIS, JH | 1 |
| MORAN, TJ | 1 |
| HURT, P | 1 |
| WEGMANN, T | 1 |
| READ, AE | 1 |
| HARRISON, CV | 1 |
| SHERLOVK, S | 1 |
| KOHN, NN | 1 |
| MYERSON, RM | 1 |
| Barancik, M | 1 |
| Brandborg, LL | 1 |
| Albion, MJ | 1 |
| Seeff, LB | 1 |
| Moradpour, D | 1 |
| Altorfer, J | 1 |
| Flury, R | 1 |
| Greminger, P | 1 |
| Meyenberger, C | 1 |
| Jost, R | 1 |
| Schmid, M | 1 |
| Morera Prat, J | 1 |
| Vidal Pla, R | 1 |
| Mari, ML | 1 |
| Olomu, AB | 1 |
| Vickers, CR | 1 |
| Waring, RH | 1 |
| Clements, D | 1 |
| Babbs, C | 1 |
| Warnes, TW | 1 |
| Elias, E | 1 |
| Kaplowitz, N | 1 |
| Aw, TY | 1 |
| Simon, FR | 1 |
| Stolz, A | 1 |
| Kühn, HA | 1 |
| Richter, E | 1 |
| Levine, RA | 1 |
| Briggs, GW | 1 |
| Lowell, DM | 1 |
| Alcalá-Santaella, R | 1 |
| Pacheco, AF | 1 |
| Robles, J | 1 |
| Bevan, G | 1 |
| Baldus, WP | 1 |
| Gleich, GJ | 1 |
3 reviews available for chlorpromazine and Liver Cirrhosis, Biliary
| Article | Year |
|---|---|
Drug-induced chronic liver disease, with emphasis on chronic active hepatitis.
Topics: Biopsy; Chemical and Drug Induced Liver Injury; Chlorpromazine; Dantrolene; Diagnosis, Differential; | 1981 |
Drug-induced hepatotoxicity.
Topics: Acetaminophen; Bile; Bile Acids and Salts; Biotransformation; Cell Survival; Chemical and Drug Induc | 1986 |
[Pathophysiology and clinical aspects of intrahepatic cholestasis].
Topics: Alkaline Phosphatase; Animals; Arsphenamine; Bile Acids and Salts; Bilirubin; Chlorpromazine; Cholan | 1970 |
11 other studies available for chlorpromazine and Liver Cirrhosis, Biliary
| Article | Year |
|---|---|
Xanthomatous biliary cirrhosis following chlorpromazine, with observations indicating overproduction of cholesterol, hyperprothrombinemia, and the development of portal hypertension.
Topics: Chlorpromazine; Cholesterol; Humans; Hypertension; Hypertension, Portal; Lipidoses; Liver Cirrhosis; | 1957 |
[Protracted Largactil jaundice developing into primary biliary cirrhosis].
Topics: Chlorpromazine; Humans; Jaundice; Liver Cirrhosis; Liver Cirrhosis, Biliary | 1961 |
Chronic chlorpromazine jaundice: with particular reference to its relationship to primary biliary cirrhosis.
Topics: Chlorpromazine; Humans; Jaundice; Jaundice, Obstructive; Liver Cirrhosis, Biliary | 1961 |
Xanthomatous biliary cirrhosis following chlorpromazine.
Topics: Chlorpromazine; Lipidoses; Liver Cirrhosis; Liver Cirrhosis, Biliary; Splenomegaly | 1961 |
Thioridazine-induced cholestasis.
Topics: Adult; Biliary Tract Diseases; Chlorpromazine; Cholestasis; Diagnosis, Differential; Humans; Liver C | 1967 |
Chlorpromazine-induced vanishing bile duct syndrome leading to biliary cirrhosis.
Topics: Adult; Bile Ducts; Biopsy; Chlorpromazine; Cholestasis; Female; Humans; Liver; Liver Cirrhosis, Bili | 1994 |
[Primary biliary cirrhosis after a prolonged ingestion of chlorpromazine].
Topics: Administration, Oral; Adult; Chlorpromazine; Female; Humans; Liver Cirrhosis, Biliary | 1976 |
High incidence of poor sulfoxidation in patients with primary biliary cirrhosis.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Carbocysteine; Chlorpromazine; Cholestasis; | 1988 |
Chronic chlorpromazine cholangiolitic hepatitis. Report of a case with immunofluorescent studies.
Topics: Adult; Chemical and Drug Induced Liver Injury; Chlorpromazine; Cholangitis; Diagnosis, Differential; | 1966 |
[Apropos of primary biliary cirrhosis induced by chlorpromazine and its therapy with cholestyramine].
Topics: Aged; Chlorpromazine; Cholestyramine Resin; Female; Humans; Liver Cirrhosis; Liver Cirrhosis, Biliar | 1968 |
Serum immunoglobulin levels in cholestasis.
Topics: Adult; Aged; Chlorpromazine; Cholelithiasis; Cholestasis; Female; Humans; Immunoglobulin G; Immunogl | 1969 |