chlorpromazine has been researched along with Leukemia P388 in 9 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Leukemia P388: An experimental lymphocytic leukemia originally induced in DBA/2 mice by painting with methylcholanthrene.
| Excerpt | Relevance | Reference |
|---|---|---|
| " A similar dose-response relationship was observed for chlorpromazine in increasing net intracellular pirarubicin accumulation." | 1.28 | [Augmentation of pirarubicin cytotoxicity by chlorpromazine in doxorubicin-resistant mouse P388 leukemia cells]. ( Furusawa, S; Kawauchi, H; Sano, F; Sasaki, K; Shibata, H; Takayanagi, Y, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (66.67) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Krishan, A | 4 |
| Bourguignon, LY | 1 |
| Shibata, H | 2 |
| Maekawa, I | 1 |
| Furusawa, S | 2 |
| Kawauchi, H | 2 |
| Takayanagi, Y | 2 |
| Sasaki, K | 2 |
| Sano, F | 1 |
| Kuramochi, H | 1 |
| Takahashi, K | 1 |
| Takeuchi, T | 1 |
| Gailis, L | 1 |
| Dumas, L | 1 |
| Page, M | 1 |
| Sauerteig, A | 1 |
| Gordon, K | 1 |
| Swinkin, C | 1 |
| Borowitz, JL | 1 |
| Hadley, R | 1 |
| Stebbins, G | 1 |
9 other studies available for chlorpromazine and Leukemia P388
| Article | Year |
|---|---|
Cell cycle related phenothiazine effects on adriamycin transport.
Topics: Animals; Biological Transport; Cell Cycle; Chlorpromazine; DNA, Neoplasm; Doxorubicin; Flow Cytometr | 1984 |
Rapid determination of cellular resistance-related drug efflux in tumor cells.
Topics: Animals; Antibiotics, Antineoplastic; Biological Transport; Chlorpromazine; Doxorubicin; Drug Resist | 1990 |
Potentiation of antitumor activity of pirarubicin by chlorpromazine in mice bearing doxorubicin-resistant P388 leukemia.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Chlorpromazine; Doxorubicin; Drug Evaluatio | 1990 |
[Augmentation of pirarubicin cytotoxicity by chlorpromazine in doxorubicin-resistant mouse P388 leukemia cells].
Topics: Animals; Antineoplastic Agents; Chlorpromazine; Doxorubicin; Drug Resistance; Drug Synergism; Leukem | 1990 |
Tumor cell permeability to peplomycin.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Carcinoma, Ehrlich Tumor; Chlorpromazine; Chromatog | 1989 |
Ambiguous effect of chlorpromazine on doxorubicin activity against P388D1 tumours in mice.
Topics: Animals; Body Weight; Chlorpromazine; Doxorubicin; Female; Leukemia P388; Leukemia, Experimental; Mi | 1988 |
Flow cytometric monitoring of anthracycline transport in tumor cells.
Topics: Animals; Antibiotics, Antineoplastic; Biological Transport; Chlorpromazine; Daunorubicin; Flow Cytom | 1986 |
Flow cytometric monitoring of cellular anthracycline accumulation in murine leukemic cells.
Topics: Animals; Biological Transport; Cell Line; Chlorpromazine; Daunorubicin; Doxorubicin; Flow Cytometry; | 1986 |
Effects of calcium and verapamil on normal and tumor murine leukocytes.
Topics: Animals; Calcium; Chlorpromazine; Ethanol; Leukemia P388; Leukemia, Experimental; Leukocytes; Mice; | 1985 |