chlorpromazine has been researched along with Leukemia L 1210 in 4 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The therapeutic usefulness of chlorpromazine (CPZ) and caffeine (CAF) in combination with selected nitrosoureas was investigated in mice bearing L1210 leukemia, Lewis lung carcinoma, and B16 melanoma." | 3.66 | Therapeutic potentiation of nitrosoureas using chlorpromazine and caffeine in the treatment of murine tumors. ( Dykes, DJ; Laster, WR; Rose, WC; Schabel, FM; Trader, MW, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rose, WC | 1 |
| Trader, MW | 1 |
| Dykes, DJ | 1 |
| Laster, WR | 1 |
| Schabel, FM | 1 |
| Kuramochi, H | 1 |
| Takahashi, K | 1 |
| Takeuchi, T | 1 |
| Lazo, JS | 1 |
| Hait, WN | 1 |
| Kennedy, KA | 1 |
| Braun, ID | 1 |
| Meandzija, B | 1 |
| Cohen, MH | 1 |
4 other studies available for chlorpromazine and Leukemia L 1210
| Article | Year |
|---|---|
Therapeutic potentiation of nitrosoureas using chlorpromazine and caffeine in the treatment of murine tumors.
Topics: Animals; Caffeine; Carmustine; Chlorpromazine; Drug Synergism; Drug Therapy, Combination; Female; Le | 1978 |
Tumor cell permeability to peplomycin.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Carcinoma, Ehrlich Tumor; Chlorpromazine; Chromatog | 1989 |
Enhanced bleomycin-induced DNA damage and cytotoxicity with calmodulin antagonists.
Topics: Animals; Bleomycin; Calmodulin; Cell Survival; Chlorpromazine; DNA; Drug Synergism; Intercellular Si | 1985 |
Brief communication: Enhancement of the antitumor effect of 1,-3-bis(2-chloroethyl)-1-nitrosourea by chlorpromazine and caffeine.
Topics: Animals; Caffeine; Carmustine; Chlorpromazine; Dose-Response Relationship, Drug; Drug Therapy, Combi | 1973 |