chlorpromazine has been researched along with Leucocythaemia in 8 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
| Excerpt | Relevance | Reference |
|---|---|---|
| "2-Chlorpromazine was shown previously [Syed SK, Christopherson RI and Roufogalis BD (1996) Biochem Mol Biol Int 39: 687-696] to be actively transported into vesicles from multidrug-resistant cells." | 1.30 | Reversal of vinblastine transport by chlorpromazine in membrane vesicles from multidrug-resistant human CCRF-CEM leukaemia cells. ( Christopherson, RI; Roufogalis, BD; Syed, SK, 1998) |
| "Chlorpromazine (CPZ) has been previously shown to protect against endotoxin [lipopolysaccharide (LPS)] lethality and inhibit the release of tumour necrosis factor in vivo." | 1.29 | Chlorpromazine inhibits tumour necrosis factor synthesis and cytotoxicity in vitro. ( Alzani, R; Cozzi, E; Demitri, MT; Fantuzzi, G; Fratelli, M; Galli, G; Ghezzi, P; Minto, M; Zinetti, M, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (62.50) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tamura, M | 1 |
| Kawano, M | 1 |
| Sato, M | 1 |
| Nashimoto, M | 1 |
| WIEK, K | 1 |
| DOAN, CA | 1 |
| DUHAMEL, M | 1 |
| Zinetti, M | 1 |
| Galli, G | 1 |
| Demitri, MT | 1 |
| Fantuzzi, G | 1 |
| Minto, M | 1 |
| Ghezzi, P | 1 |
| Alzani, R | 1 |
| Cozzi, E | 1 |
| Fratelli, M | 1 |
| Syed, SK | 1 |
| Christopherson, RI | 1 |
| Roufogalis, BD | 1 |
| Weisenthal, LM | 1 |
| Su, YZ | 1 |
| Duarte, TE | 1 |
| Dill, PL | 1 |
| Nagourney, RA | 1 |
| Ter-Grigorova, EN | 1 |
| Afanas'eva, VM | 1 |
| Ivanovskaia, TE | 1 |
8 other studies available for chlorpromazine and Leucocythaemia
| Article | Year |
|---|---|
Involvement of an intracellular vesicular transport process in naked-sgRNA-mediated TRUE gene silencing.
Topics: Apoptosis; bcl-2-Associated X Protein; beta-Cyclodextrins; Cell Line, Tumor; Chlorpromazine; Endocyt | 2015 |
[ON THE CLINICAL ASPECTS OF AGRANULOCYTOSIS].
Topics: Agranulocytosis; Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Chlorpromazine; Dr | 1964 |
APLASTIC VERSUS HYPERPLASTIC BLOOD DYSCRASIAS.
Topics: Anemia; Anemia, Aplastic; Anti-Bacterial Agents; Benzene; Bone Marrow Diseases; Chlorpromazine; Coba | 1964 |
[AGRANULOCYTOSIS AND NEUTROPENIA].
Topics: Adrenal Cortex Hormones; Agranulocytosis; Aminopyrine; Analgesics; Analgesics, Non-Narcotic; Antipyr | 1964 |
Chlorpromazine inhibits tumour necrosis factor synthesis and cytotoxicity in vitro.
Topics: Apoptosis; Cell Line; Chlorpromazine; Cytotoxicity Tests, Immunologic; Depression, Chemical; Humans; | 1995 |
Reversal of vinblastine transport by chlorpromazine in membrane vesicles from multidrug-resistant human CCRF-CEM leukaemia cells.
Topics: Biological Transport; Calcium; Cell Membrane; Chlorpromazine; Colchicine; Drug Resistance, Multiple; | 1998 |
Perturbation of in vitro drug resistance in human lymphatic neoplasms by combinations of putative inhibitors of protein kinase C.
Topics: Cell Survival; Chlorpromazine; Drug Resistance; Drug Synergism; Haloperidol; Humans; Imipramine; In | 1987 |
[Pathology of therapy and pathomorphosis of some diseases in children].
Topics: Adrenal Cortex Hormones; Adrenal Insufficiency; Anti-Bacterial Agents; Antimetabolites; Bone and Bon | 1967 |