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chlorpromazine and Leishmaniasis

chlorpromazine has been researched along with Leishmaniasis in 5 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Leishmaniasis: A disease caused by any of a number of species of protozoa in the genus LEISHMANIA. There are four major clinical types of this infection: cutaneous (Old and New World) (LEISHMANIASIS, CUTANEOUS), diffuse cutaneous (LEISHMANIASIS, DIFFUSE CUTANEOUS), mucocutaneous (LEISHMANIASIS, MUCOCUTANEOUS), and visceral (LEISHMANIASIS, VISCERAL).

Research Excerpts

ExcerptRelevanceReference
"Chlorpromazine (CPZ) was effective in vitro against leishmanial promastigotes and amastigotes."1.27In vitro and in vivo anti-leishmanial activity of chlorpromazine alone and combined with N-meglumine antimonate. ( el-On, J; Kernbaum, S; Rubinstein, N; Schnur, LF, 1986)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19905 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Henriksen, TH1
Lende, S1
Evans, AT2
Croft, SL2
Peters, W1
el-On, J1
Rubinstein, N1
Kernbaum, S1
Schnur, LF1
Neal, RA1
Várnai, F1
Fülöp, E1
Bánhegyi, D1

Other Studies

5 other studies available for chlorpromazine and Leishmaniasis

ArticleYear
Treatment of diffuse cutaneous leishmaniasis with chlorpromazine ointment.
    Lancet (London, England), 1983, Jan-15, Volume: 1, Issue:8316

    Topics: Chlorpromazine; Humans; Leishmaniasis; Ointments

1983
Failure of chlorpromazine or amitriptyline ointments to influence the course of experimental cutaneous leishmaniasis.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1988, Volume: 82, Issue:2

    Topics: Amitriptyline; Animals; Chlorpromazine; Leishmaniasis; Mice; Mice, Inbred Strains; Ointments

1988
In vitro and in vivo anti-leishmanial activity of chlorpromazine alone and combined with N-meglumine antimonate.
    Annals of tropical medicine and parasitology, 1986, Volume: 80, Issue:5

    Topics: Animals; Antiprotozoal Agents; Chlorpromazine; Drug Therapy, Combination; Leishmania; Leishmaniasis;

1986
The activity of plumbagin and other electron carriers against Leishmania donovani and Leishmania mexicana amazonensis.
    Annals of tropical medicine and parasitology, 1985, Volume: 79, Issue:6

    Topics: Animals; Antiprotozoal Agents; Chlorpromazine; Clofazimine; Electron Transport; Leishmania donovani;

1985
[Cases of cutaneous leishmaniasis imported by Hungarian citizens].
    Orvosi hetilap, 1985, Oct-13, Volume: 126, Issue:41

    Topics: Administration, Topical; Chloroquine; Chlorpromazine; Humans; Hungary; Leishmaniasis; Travel; Tropic

1985