chlorpromazine has been researched along with Kidney Failure, Chronic in 10 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the importance of disease-induced increases in plasma concentrations of alpha1 acid glycoprotein (an acute-phase plasma protein that binds cationic drugs), we determined binding of propranolol in plasma from 53 patients and 25 healthy volunteers." | 7.66 | Increased plasma protein binding of propranolol and chlorpromazine mediated by disease-induced elevations of plasma alpha1 acid glycoprotein. ( Borgá, O; Johansson, C; Odar-Cederlöf, I; Piafsky, KM; Sjöqvist, F, 1978) |
| "To assess the importance of disease-induced increases in plasma concentrations of alpha1 acid glycoprotein (an acute-phase plasma protein that binds cationic drugs), we determined binding of propranolol in plasma from 53 patients and 25 healthy volunteers." | 3.66 | Increased plasma protein binding of propranolol and chlorpromazine mediated by disease-induced elevations of plasma alpha1 acid glycoprotein. ( Borgá, O; Johansson, C; Odar-Cederlöf, I; Piafsky, KM; Sjöqvist, F, 1978) |
| "A case of sudden death following chlorpromazine administration in a schizophrenic patient is presented." | 1.27 | Chlorpromazine accumulation and sudden death in a patient with renal insufficiency. ( Crismon, ML; Dorson, PG, 1988) |
| "Four patients with chronic renal failure requiring hemodialysis were given doses of chlorpromazine ranging from 100--1000 mg over time intervals varying from 2--7 days." | 1.26 | Toxic psychosis induced by phenothiazine administration in patients with chronic renal failure. ( McAllister, CJ; Scowden, EB; Stone, WJ, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (90.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fabre, J | 2 |
| de Freudenreich, J | 2 |
| Duckert, A | 2 |
| Pitton, JS | 2 |
| Rudhardt, M | 2 |
| Virieux, C | 1 |
| Grzeszczak, W | 1 |
| Kokot, F | 1 |
| Dulawa, J | 1 |
| Piafsky, KM | 1 |
| Borgá, O | 1 |
| Odar-Cederlöf, I | 1 |
| Johansson, C | 1 |
| Sjöqvist, F | 1 |
| Ramirez, G | 1 |
| O'Neill, WM | 1 |
| Bloomer, HA | 1 |
| Jubiz, W | 1 |
| McAllister, CJ | 1 |
| Scowden, EB | 1 |
| Stone, WJ | 1 |
| Kalra, OP | 1 |
| Aggarwal, HK | 1 |
| Mahajan, SK | 1 |
| Seth, RK | 1 |
| Dorson, PG | 1 |
| Crismon, ML | 1 |
| Stage, P | 1 |
| Milman, N | 1 |
| Brix, E | 1 |
| Murphy, KJ | 1 |
1 trial available for chlorpromazine and Kidney Failure, Chronic
| Article | Year |
|---|---|
Effect of vasodilator and surface active drugs on the efficacy of peritoneal dialysis.
Topics: Acute Kidney Injury; Adult; Aged; Chlorpromazine; Dialysis Solutions; Female; Humans; Kidney Failure | 1992 |
9 other studies available for chlorpromazine and Kidney Failure, Chronic
| Article | Year |
|---|---|
Influence of renal insufficiency on the excretion of chloroquine, phenobarbital, phenothiazines and methacycline.
Topics: Adult; Aged; Chloroquine; Chlorpromazine; Glomerular Filtration Rate; Humans; Kidney Failure, Chroni | 1967 |
Influence of naloxone on prolactin secretion in patients with acute and chronic renal failure.
Topics: Acute Kidney Injury; Adult; Chlorpromazine; Female; Humans; Kidney Failure, Chronic; Male; Naloxone; | 1984 |
Increased plasma protein binding of propranolol and chlorpromazine mediated by disease-induced elevations of plasma alpha1 acid glycoprotein.
Topics: Adult; Aged; alpha-Macroglobulins; Arthritis; Chlorpromazine; Crohn Disease; Disease; Female; Humans | 1978 |
Abnormalities in the regulation of prolactin in patients with chronic renal failure.
Topics: Adult; Chlorpromazine; Humans; Kidney Failure, Chronic; Levodopa; Male; Middle Aged; Prolactin; Thyr | 1977 |
Toxic psychosis induced by phenothiazine administration in patients with chronic renal failure.
Topics: Aged; Chlorpromazine; Humans; Kidney Failure, Chronic; Male; Middle Aged; Promethazine; Psychoses, S | 1978 |
Chlorpromazine accumulation and sudden death in a patient with renal insufficiency.
Topics: Chlorpromazine; Death, Sudden; Humans; Kidney Failure, Chronic; Male; Middle Aged; Schizophrenia | 1988 |
High-dose urography in advanced renal failure. I. Evaluation of diagnostic value.
Topics: Acute Kidney Injury; Adult; Aged; Aniline Compounds; Benzyl Compounds; Blood Urea Nitrogen; Blood Vi | 1973 |
[Influence of renal insufficiency on the excretion of diverse drugs (chloroquine, sedatives, methacycline)].
Topics: Barbiturates; Chloroquine; Chlorpromazine; Creatinine; Humans; Hypnotics and Sedatives; Kidney Failu | 1966 |
Uraemic accentuation of chlorpromazine pigmentation.
Topics: Adult; Chlorpromazine; Conjunctiva; Humans; Kidney Failure, Chronic; Male; Melanosis; Nausea; Uremia | 1966 |