chlorpromazine has been researched along with Intraocular Pressure in 34 studies
Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.
Intraocular Pressure: The pressure of the fluids in the eye.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To report the efficacy of primary retrobulbar chlorpromazine injections for the management of blind and seeing painful eyes." | 9.10 | Retrobulbar chlorpromazine injections for the management of blind and seeing painful eyes. ( Ahn Yuen, SJ; Chen, TC; Fernando, RE; Leuenberger, EU; Sangalang, MA, 2002) |
| "Intramuscular injection of chlorpromazine in rabbits caused a significant decrease in intraocular pressure (IOP)." | 7.67 | Intramuscular injection of chlorpromazine decreases intraocular pressure by lowering systemic blood pressure. ( Dacus, AC; Liu, JH, 1989) |
| "To report the efficacy of primary retrobulbar chlorpromazine injections for the management of blind and seeing painful eyes." | 5.10 | Retrobulbar chlorpromazine injections for the management of blind and seeing painful eyes. ( Ahn Yuen, SJ; Chen, TC; Fernando, RE; Leuenberger, EU; Sangalang, MA, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (88.24) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (5.88) | 29.6817 |
| 2010's | 2 (5.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Galindo-Ferreiro, A | 1 |
| Akaishi, P | 1 |
| Cruz, A | 1 |
| Khandekar, R | 1 |
| Al Dosairi, S | 1 |
| Dufaileej, M | 1 |
| Al Salem, A | 1 |
| Galvez-Ruiz, A | 1 |
| Craven, ER | 1 |
| Kuruvilla, R | 1 |
| Sahu, PD | 1 |
| Meltzer, MA | 1 |
| Cioffi, GA | 1 |
| Chen, TC | 1 |
| Ahn Yuen, SJ | 1 |
| Sangalang, MA | 1 |
| Fernando, RE | 1 |
| Leuenberger, EU | 1 |
| WISTRAND, P | 1 |
| WAITZMAN, MB | 1 |
| DAL FIUME, E | 1 |
| GUERRINI, O | 1 |
| BOCK, R | 1 |
| SWAIN, J | 1 |
| REHAK, S | 1 |
| SKRANC, O | 1 |
| JURAN, J | 1 |
| BHATNAGAR, BS | 1 |
| GEORGIADES, G | 1 |
| KYRATSOS, C | 1 |
| MICHAILIDES, G | 1 |
| TSINOPOULOS, T | 1 |
| MIKHEEVA, EG | 1 |
| Wood, WB | 1 |
| Powers, MF | 1 |
| Hamilton, RS | 1 |
| Ramos, L | 2 |
| Caldeira, JA | 2 |
| Ramos, AO | 2 |
| Gol'dovskaia, IL | 1 |
| Smolen, VF | 1 |
| de Feo, G | 1 |
| Piccinelli, D | 2 |
| Putzolu, S | 1 |
| Silverstrini, B | 1 |
| Liu, JH | 1 |
| Dacus, AC | 1 |
| Treister, G | 1 |
| Bárány, EH | 1 |
| MacDougald, TJ | 1 |
| Pecoldowa, K | 2 |
| Macri, FJ | 1 |
| Mathalone, MB | 1 |
| Marré, E | 1 |
| Schmiedeberg, W | 1 |
| Thiel, HJ | 1 |
| van Zwieten, PA | 1 |
| Isayama, Y | 1 |
| Yasui, T | 1 |
| Burberi, P | 1 |
| Silvestrini, B | 1 |
| Arita, M | 1 |
| Mashiba, H | 1 |
| Sarmány, BJ | 1 |
| Pecold, K | 1 |
| Romashenkov, FA | 1 |
| Gershteĭn, LM | 1 |
| Giesbrecht, AM | 1 |
| Siddall, JR | 1 |
2 reviews available for chlorpromazine and Intraocular Pressure
| Article | Year |
|---|---|
[Psychotropic therapy and intraocular pressure].
Topics: Amitriptyline; Analgesics; Antidepressive Agents; Chlorpromazine; Diazepam; Diphenhydramine; Eye Dis | 1975 |
Pharmacology and toxicology of ophthalmic drugs.
Topics: Adrenal Cortex Hormones; Animals; Anti-Bacterial Agents; Cats; Chlorpromazine; Ciliary Body; Cornea; | 1969 |
4 trials available for chlorpromazine and Intraocular Pressure
| Article | Year |
|---|---|
Retrobulbar Injections for Blind Painful Eyes: A Comparative Study of Retrobulbar Alcohol Versus Chlorpromazine.
Topics: Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Blindness; Central Nervous System Depressants; | 2016 |
Retrobulbar chlorpromazine injections for the management of blind and seeing painful eyes.
Topics: Adolescent; Adult; Aged; Blindness; Child; Chlorpromazine; Dopamine Antagonists; Female; Glaucoma; H | 2002 |
[Experimental and clinical studies on drugs limiting the increase of intraocular pressure under the effect of succinylcholine. 3. Clinical studies on the effect of chlorpromazine, glycerin and acetazolamide].
Topics: Acetazolamide; Chlorpromazine; Clinical Trials as Topic; Glaucoma; Glycerol; Humans; Intraocular Pre | 1968 |
[Prevention of intraocular pressure increase after succinylcholine].
Topics: Acetazolamide; Anesthesia, General; Chlorpromazine; Glaucoma; Glycerol; Humans; Injections, Intramus | 1967 |
28 other studies available for chlorpromazine and Intraocular Pressure
| Article | Year |
|---|---|
Systemic uptake of chlorpromazine after delivery via retrobulbar injection.
Topics: Antipsychotic Agents; Arrhythmias, Cardiac; Chlorpromazine; Dizziness; Electrocardiography; Eye Pain | 2012 |
If it chance your eye offend you: the blind painful eye.
Topics: Aged; Blindness; Chlorpromazine; Ciliary Body; Dopamine Antagonists; Eye Enucleation; Glaucoma; Glau | 2002 |
The failure of promethazine and chlorpromazine to prevent the eye-pressure response to local irritation of the iris.
Topics: Chlorpromazine; Eye Diseases; Humans; Intraocular Pressure; Iris; Promethazine; Tonometry, Ocular | 1958 |
Influences of chlorpromazine on aqueous humor dynamics.
Topics: Aqueous Humor; Chlorpromazine; Eye Diseases; Intraocular Pressure; Tonometry, Ocular | 1963 |
[Effects of the fluothanechlorpromazine combination on arterial pressure, venous pressure and ophthalmic tonus].
Topics: Blood Pressure; Blood Pressure Determination; Cataract Extraction; Chlorpromazine; Eye; Halothane; H | 1962 |
OPHTHALMOLOGIC FINDINGS IN PATIENTS ON LONG-TERM CHLORPROMAZINE THERAPY.
Topics: Chlorpromazine; Eye Diseases; Glaucoma; Intraocular Pressure; Ophthalmology; Photosensitivity Disord | 1963 |
[ATTEMPT AT COMBINED BLOCKADE OF VOLUME REACTIVE HYPERTENSION].
Topics: Animals; Aqueous Humor; Carotid Arteries; Chlorpromazine; Hypertension; Hypertonic Solutions; Intrao | 1964 |
INTRA-OCULAR PRESSURE IN CATARACT SURGERY.
Topics: Cataract; Cataract Extraction; Chlorpromazine; Humans; Intraocular Pressure; Phenobarbital; Preopera | 1964 |
[OCULAR PRESSURE, NEUROLEPTIC AGENTS AND PARKINSONIAN STATES].
Topics: Antipsychotic Agents; Chlorpromazine; Haloperidol; Intraocular Pressure; Methotrimeprazine; Parkinso | 1963 |
[EFFECT OF EXPERIMENTAL ROENTGEN IRRADIATION ON INTRAOCULAR PRESSURE AND PERMEABILITY OF OCULAR VESSELS].
Topics: Animals; Bis-Trimethylammonium Compounds; Chlorpromazine; Intraocular Pressure; Permeability; Pharma | 1964 |
Effects of transcranial electric currents on intraocular and cerebrospinal fluid pressures.
Topics: Animals; Arteries; Atropine; Blood Pressure; Cerebrospinal Fluid; Chlorpromazine; Dogs; Electricity; | 1967 |
Influence of chlorpromazine intracisternal injection on the intraocular pressure of the rabbit.
Topics: Animals; Chlorpromazine; Injections, Intravenous; Intraocular Pressure; Rabbits | 1967 |
Proceedings: Bioavailability and pharmacokinetic analysis of chlorpromazine in humans and animals using pharmacological data.
Topics: Animals; Biological Availability; Blood Pressure; Chlorpromazine; Dose-Response Relationship, Drug; | 1974 |
Effects of topically instilled drugs on intraocular pressure in rabbits.
Topics: Acetazolamide; Administration, Topical; Amphetamine; Animals; Blood Pressure; Chlorothiazide; Chlorp | 1975 |
Intramuscular injection of chlorpromazine decreases intraocular pressure by lowering systemic blood pressure.
Topics: Animals; Blood Pressure; Central Nervous System; Chlorpromazine; Dose-Response Relationship, Drug; F | 1989 |
Degeneration mydriasis and hyperemia of the iris after superior cervical ganglionectomy in the rabbit. Evidence for release of more than norepinephrine during degeneration of adrenergic terminals.
Topics: Accommodation, Ocular; Adrenergic alpha-Antagonists; Animals; Atropine; Bretylium Compounds; Chlorpr | 1970 |
The treatment of traumatic hyphaema.
Topics: Chlorpromazine; Eye Injuries; Humans; Hyphema; Intraocular Pressure; Pilocarpine; Promethazine; Rest | 1972 |
Ocular complications of phenothiazines.
Topics: Adult; Chlorpromazine; Conjunctiva; Cornea; Eye Diseases; Female; Fundus Oculi; Humans; Intraocular | 1966 |
[Intraocular pressure regulation. II. Modification of the intraocular pressure regulation by drugs with various central nervous system effectiveness].
Topics: Animals; Body Weight; Chlorpromazine; Infusions, Parenteral; Intraocular Pressure; Phenelzine; Rabbi | 1968 |
The influence of drugs involved in general anaesthesia and of antihypertensive agents on intraocular and blood pressure in the rabbit.
Topics: Acetazolamide; Anesthesia, General; Anesthetics; Animals; Antihypertensive Agents; Barbiturates; Ben | 1971 |
[Glaucomatous symptoms produced by the possible side effects after administration of massive doses of psychodrugs. II].
Topics: Adult; Chlorpromazine; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Schizophre | 1970 |
Effects of systemically administered drugs on intraocular pressure in rabbits.
Topics: Acetazolamide; Amphetamine; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Blood Pressu | 1970 |
Effects of phenothiazine and propranolol on ECG. The effects of propranolol on the electrocardiographic abnormalities induced by phenothiazine derivatives.
Topics: Adult; Blood Pressure; Chlorpromazine; Electrocardiography; Female; Fluphenazine; Heart; Heart Rate; | 1970 |
[On the effect of various narcotics on intraocular pressure].
Topics: Adult; Anesthesia, General; Anesthetics; Barbiturates; Chlorpromazine; Female; Halothane; Humans; In | 1967 |
Experimental and clinical investigations of drugs limiting the rise of intraocular tension caused by succinylcholine. 3. Clinical studies on the effect of chloropromazine, glycerol and acetazoleamide.
Topics: Acetazolamide; Anesthesia, General; Barbiturates; Chlorpromazine; Glycerol; Intraocular Pressure; Pr | 1968 |
[The distribution and concentration of nucleic acids and proteins in the structural elements of the rabbit eye following aminazin administration].
Topics: Animals; Chlorpromazine; Eye Proteins; Intraocular Pressure; Rabbits; Retina; RNA | 1968 |
Changes of intraocular pressure and of chloride, sodium and potassium concentrations in aqueous humor and serum of rabbits following chlorpromazine.
Topics: Acetazolamide; Animals; Aqueous Humor; Chlorides; Chlorpromazine; Ethanol; Female; Intraocular Press | 1969 |
Ocular toxic changes associated with chlorpromazine and thioridazine.
Topics: Adolescent; Adult; Aged; Cataract; Chlorpromazine; Eye; Female; Fundus Oculi; Gonioscopy; Humans; In | 1966 |