Page last updated: 2024-10-25

chlorpromazine and Intestinal Obstruction

chlorpromazine has been researched along with Intestinal Obstruction in 26 studies

Chlorpromazine: The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
chlorpromazine : A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety.

Intestinal Obstruction: Any impairment, arrest, or reversal of the normal flow of INTESTINAL CONTENTS toward the ANAL CANAL.

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199026 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
REIFFERSCHEID, M1
BARNETT, DA1
WENDEL, OW1
CHARKEY, LW1
Grenier, J1
Ruelland, R1
TURAI, I1
FONI, I1
PAUSESCU, E1
CIUREL, M1
YAMASHITA, Y1
Warnes, H1
Lehmann, HE1
Ban, TA1
Grund, KE2
Jügelt, U1
Catania, A1
Caimi, G1
Falterman, CG1
Richardson, CJ1
Nechaĭ, AI1
Ostrovskaia, MS1
Watts, GT1
Giordano, J1
Canter, JW1
Huang, A1
Kinnaert, P1
Panda, M1
Deuvaert, F1
Sriram, K1
Schumer, W1
Ehrenpreis, S1
Comaty, JE1
Scheller, J1
Petri, G3
Tárnoky, K1
Szenohradszky, J2
Matkó, I1
Vasilev, N1
Ianchev, D1
Filipov, A1
Sorbie, C1
Furness, JB1
Costa, M1
Pórszász, J2
Pórszász-Gibiszer, K1
Davis, JT1
Nusbaum, M1
Milner, G1
Kaltiala, EH1
Summers, RW1
Kent, TH1
Osborne, JW1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Mosapride on Postoperative Ileus in Patients Undergoing Colorectal Surgery[NCT02056405]Phase 490 participants (Anticipated)Interventional2015-12-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for chlorpromazine and Intestinal Obstruction

ArticleYear
Adynamic ileus, its pathogenesis and treatment.
    Medical biology, 1974, Volume: 52, Issue:2

    Topics: Bethanechol Compounds; Chlorpromazine; Ganglia, Autonomic; Gastrointestinal Motility; Guanethidine;

1974
Gastro-intestinal side effects and psychotropic drugs.
    The Medical journal of Australia, 1969, Jul-19, Volume: 2, Issue:3

    Topics: Amitriptyline; Animals; Chlorpromazine; Constipation; Digestive System; Drug Synergism; Ethanol; Gas

1969

Other Studies

24 other studies available for chlorpromazine and Intestinal Obstruction

ArticleYear
[Ileus shock and an attempt of its control in animal experiments].
    Langenbecks Archiv fur klinische Chirurgie ... vereinigt mit Deutsche Zeitschrift fur Chirurgie, 1954, Volume: 279

    Topics: Animal Experimentation; Animals; Chlorpromazine; Ileus; Intestinal Obstruction; Shock; Sympatholytic

1954
Chlorpromazine as masking agent intestinal obstruction.
    The Journal of the Oklahoma State Medical Association, 1958, Volume: 51, Issue:1

    Topics: Chlorpromazine; Humans; Intestinal Obstruction

1958
Influence of environmental temperature and chlorpromazine on biochemical changes following bowel shock.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1958, Volume: 98, Issue:3

    Topics: Chlorpromazine; Intestinal Obstruction; Intestines; Shock; Temperature

1958
[He was paralytic and chlorpromazine].
    Laval medical, 1959, Volume: 27, Issue:5

    Topics: Chlorpromazine; Intestinal Obstruction

1959
[Influence of certain ganglioplegic and neuroplegic substances on the evolution of experimental intestinal occlusions].
    Probleme de terapeutica, 1959, Volume: 10(4)

    Topics: Bis-Trimethylammonium Compounds; Chlorpromazine; Intestinal Obstruction

1959
[VOMITING IN INFANTS AND PREVENTIVE MEASURES, WITH SPECIAL REFERENCE TO INTESTINAL OBSTRUCTION].
    [Chiryo] [Therapy], 1963, Volume: 45

    Topics: Atropine; Chlorpromazine; Esophageal Achalasia; Humans; Infant; Infant, Newborn; Intestinal Obstruct

1963
Adynamic ileus during psychoactive medication: a report of three fatal and five severe cases.
    Canadian Medical Association journal, 1967, Apr-15, Volume: 96, Issue:15

    Topics: Adult; Chlorpromazine; Female; Humans; Imipramine; Intestinal Obstruction; Male; Mental Disorders; M

1967
[Treatment of ileus with sympathicolysis: therapy protocol].
    Intensivmedizinische Praxis, 1983, Volume: 6

    Topics: Auscultation; Ceruletide; Chlorpromazine; Dihydroergotamine; Gastrointestinal Motility; Humans; Infu

1983
[Acute intermittent porphyria].
    Minerva medica, 1983, Nov-10, Volume: 74, Issue:43

    Topics: Acute Disease; Chlorpromazine; Diarrhea; Heme; Hemin; Humans; Intestinal Obstruction; Mitochondria,

1983
[Treatment of functional ileus: adrenergic blockade and stimulation (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1982, Feb-12, Volume: 107, Issue:6

    Topics: Adolescent; Adult; Aged; Ceruletide; Child; Child, Preschool; Chlorpromazine; Dihydroergotamine; Fem

1982
Small left colon syndrome associated with maternal ingestion of psychotropic drugs.
    The Journal of pediatrics, 1980, Volume: 97, Issue:2

    Topics: Benztropine; Biperiden; Chlorpromazine; Colonic Diseases, Functional; Doxepin; Female; Humans; Infan

1980
[Use of preparations with sympatholytic activity for prevention and treatment of postoperative intestinal paresis].
    Vestnik khirurgii imeni I. I. Grekova, 1977, Volume: 118, Issue:1

    Topics: Adrenergic alpha-Antagonists; Chlorpromazine; Ganglionic Blockers; Hexamethonium Compounds; Humans;

1977
Chlorpromazine and fluid-loss in cholera.
    Lancet (London, England), 1979, Mar-17, Volume: 1, Issue:8116

    Topics: Chlorpromazine; Flatulence; Humans; Intestinal Obstruction; Intestinal Pseudo-Obstruction; Peristals

1979
Fatal paralytic ileus complicating phenothiazine therapy.
    Southern medical journal, 1975, Volume: 68, Issue:3

    Topics: Adult; Antipsychotic Agents; Benztropine; Chlorpromazine; Colon; Female; Humans; Intestinal Mucosa;

1975
Use of chlorpromazine in the treatment of adynamic ileus.
    World journal of surgery, 1977, Volume: 1, Issue:5

    Topics: Adult; Aged; Chlorpromazine; Female; Humans; Intestinal Obstruction; Intestinal Pseudo-Obstruction;

1977
Phenothiazine effect on gastrointestinal tract function.
    American journal of surgery, 1979, Volume: 137, Issue:1

    Topics: Animals; Chlorpromazine; Dilatation, Pathologic; Electric Stimulation; Gastrointestinal Motility; Gu

1979
[Sympatholytic therapy of paralytic ileus].
    Minerva medica, 1975, Jun-09, Volume: 66, Issue:42

    Topics: Caffeine; Catecholamines; Chlorpromazine; Drug Therapy, Combination; Humans; Intestinal Obstruction;

1975
[Method of combined sympathetic blockade for preventing postoperative intestinal paralysis].
    Khirurgiia, 1985, Volume: 38, Issue:2

    Topics: Adult; Aged; Autonomic Nerve Block; Chlorpromazine; Female; Humans; Intestinal Obstruction; Intestin

1985
Peristalsis and sympathetic activity.
    Lancet (London, England), 1968, Apr-13, Volume: 1, Issue:7546

    Topics: Chlorpromazine; Humans; Intestinal Obstruction; Spinal Injuries; Sympathetic Nervous System

1968
The action of sympatholytic drugs in experimental intestinal paralysis.
    Acta chirurgica Academiae Scientiarum Hungaricae, 1971, Volume: 12, Issue:4

    Topics: Anesthesia; Animals; Cats; Chlorpromazine; Disease Models, Animal; Ganglionic Blockers; Gastrointest

1971
Chlorpromazine therapy and functional large bowel obstruction.
    The American journal of gastroenterology, 1973, Volume: 60, Issue:6

    Topics: Affective Symptoms; Chlorpromazine; Colon; Colonic Diseases, Functional; Humans; Intestinal Obstruct

1973
The effect of intestinal obstruction on liver microsomal enzymes in rats.
    Acta chirurgica Scandinavica. Supplementum, 1968, Volume: 402

    Topics: Anesthesia; Animals; Body Temperature; Body Weight; Chlorpromazine; Hematocrit; Intestinal Obstructi

1968
Effects of drugs, ileal obstruction, and irradiation on rat gastrointestinal propulsion.
    Gastroenterology, 1970, Volume: 59, Issue:5

    Topics: Animals; Chlorisondamine; Chlorpromazine; Chromium Isotopes; Fasting; Gastrointestinal Motility; Ile

1970
[Pathogenesis and a new therapy of "paralytic ileus"].
    Langenbecks Archiv fur Chirurgie, 1968, Volume: 322

    Topics: Animals; Butyrophenones; Cats; Chlorpromazine; Gastrointestinal Motility; Humans; Intestinal Obstruc

1968